JP2017502666A5 - - Google Patents

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Publication number
JP2017502666A5
JP2017502666A5 JP2016542737A JP2016542737A JP2017502666A5 JP 2017502666 A5 JP2017502666 A5 JP 2017502666A5 JP 2016542737 A JP2016542737 A JP 2016542737A JP 2016542737 A JP2016542737 A JP 2016542737A JP 2017502666 A5 JP2017502666 A5 JP 2017502666A5
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JP
Japan
Prior art keywords
bioreactor
standing wave
acoustic standing
cell separator
fluid communication
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JP2016542737A
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English (en)
Japanese (ja)
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JP2017502666A (ja
JP6896242B2 (ja
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Priority claimed from PCT/SE2014/051575 external-priority patent/WO2015102528A1/en
Publication of JP2017502666A publication Critical patent/JP2017502666A/ja
Publication of JP2017502666A5 publication Critical patent/JP2017502666A5/ja
Application granted granted Critical
Publication of JP6896242B2 publication Critical patent/JP6896242B2/ja
Expired - Fee Related legal-status Critical Current
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JP2016542737A 2013-12-30 2014-12-29 細胞培養のための装置 Expired - Fee Related JP6896242B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361921626P 2013-12-30 2013-12-30
US61/921,626 2013-12-30
US201461983482P 2014-04-24 2014-04-24
US61/983,482 2014-04-24
PCT/SE2014/051575 WO2015102528A1 (en) 2013-12-30 2014-12-29 Apparatus for cell cultivation

Publications (3)

Publication Number Publication Date
JP2017502666A JP2017502666A (ja) 2017-01-26
JP2017502666A5 true JP2017502666A5 (enExample) 2018-02-15
JP6896242B2 JP6896242B2 (ja) 2021-06-30

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Family Applications (1)

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JP2016542737A Expired - Fee Related JP6896242B2 (ja) 2013-12-30 2014-12-29 細胞培養のための装置

Country Status (4)

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US (2) US20160312168A1 (enExample)
EP (1) EP3089800A4 (enExample)
JP (1) JP6896242B2 (enExample)
WO (1) WO2015102528A1 (enExample)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8691145B2 (en) 2009-11-16 2014-04-08 Flodesign Sonics, Inc. Ultrasound and acoustophoresis for water purification
US10689609B2 (en) 2012-03-15 2020-06-23 Flodesign Sonics, Inc. Acoustic bioreactor processes
US9272234B2 (en) 2012-03-15 2016-03-01 Flodesign Sonics, Inc. Separation of multi-component fluid through ultrasonic acoustophoresis
US9796956B2 (en) 2013-11-06 2017-10-24 Flodesign Sonics, Inc. Multi-stage acoustophoresis device
US9745548B2 (en) 2012-03-15 2017-08-29 Flodesign Sonics, Inc. Acoustic perfusion devices
US9752113B2 (en) 2012-03-15 2017-09-05 Flodesign Sonics, Inc. Acoustic perfusion devices
US9458450B2 (en) 2012-03-15 2016-10-04 Flodesign Sonics, Inc. Acoustophoretic separation technology using multi-dimensional standing waves
US10704021B2 (en) 2012-03-15 2020-07-07 Flodesign Sonics, Inc. Acoustic perfusion devices
US9950282B2 (en) 2012-03-15 2018-04-24 Flodesign Sonics, Inc. Electronic configuration and control for acoustic standing wave generation
US9752114B2 (en) 2012-03-15 2017-09-05 Flodesign Sonics, Inc Bioreactor using acoustic standing waves
US10967298B2 (en) 2012-03-15 2021-04-06 Flodesign Sonics, Inc. Driver and control for variable impedence load
US10370635B2 (en) 2012-03-15 2019-08-06 Flodesign Sonics, Inc. Acoustic separation of T cells
US10953436B2 (en) 2012-03-15 2021-03-23 Flodesign Sonics, Inc. Acoustophoretic device with piezoelectric transducer array
US9567559B2 (en) 2012-03-15 2017-02-14 Flodesign Sonics, Inc. Bioreactor using acoustic standing waves
US9783775B2 (en) 2012-03-15 2017-10-10 Flodesign Sonics, Inc. Bioreactor using acoustic standing waves
US10322949B2 (en) 2012-03-15 2019-06-18 Flodesign Sonics, Inc. Transducer and reflector configurations for an acoustophoretic device
US10737953B2 (en) 2012-04-20 2020-08-11 Flodesign Sonics, Inc. Acoustophoretic method for use in bioreactors
US9745569B2 (en) 2013-09-13 2017-08-29 Flodesign Sonics, Inc. System for generating high concentration factors for low cell density suspensions
CN105939767B (zh) 2014-01-08 2018-04-06 弗洛设计声能学公司 具有双声电泳腔的声电泳装置
US9744483B2 (en) 2014-07-02 2017-08-29 Flodesign Sonics, Inc. Large scale acoustic separation device
US9944894B2 (en) 2015-01-16 2018-04-17 General Electric Company Pluripotent stem cell expansion and passage using a rocking platform bioreactor
US10106770B2 (en) 2015-03-24 2018-10-23 Flodesign Sonics, Inc. Methods and apparatus for particle aggregation using acoustic standing waves
US11021699B2 (en) 2015-04-29 2021-06-01 FioDesign Sonics, Inc. Separation using angled acoustic waves
US11708572B2 (en) 2015-04-29 2023-07-25 Flodesign Sonics, Inc. Acoustic cell separation techniques and processes
US11377651B2 (en) 2016-10-19 2022-07-05 Flodesign Sonics, Inc. Cell therapy processes utilizing acoustophoresis
US11459540B2 (en) 2015-07-28 2022-10-04 Flodesign Sonics, Inc. Expanded bed affinity selection
US11474085B2 (en) 2015-07-28 2022-10-18 Flodesign Sonics, Inc. Expanded bed affinity selection
WO2017180814A1 (en) * 2016-04-15 2017-10-19 Boehringer Ingelheim International Gmbh Cell retention device and method
US10710006B2 (en) 2016-04-25 2020-07-14 Flodesign Sonics, Inc. Piezoelectric transducer for generation of an acoustic standing wave
US11214789B2 (en) 2016-05-03 2022-01-04 Flodesign Sonics, Inc. Concentration and washing of particles with acoustics
US11085035B2 (en) 2016-05-03 2021-08-10 Flodesign Sonics, Inc. Therapeutic cell washing, concentration, and separation utilizing acoustophoresis
CN114891635A (zh) 2016-05-03 2022-08-12 弗洛设计声能学公司 利用声泳的治疗细胞洗涤、浓缩和分离
EP3500659A1 (en) * 2016-08-16 2019-06-26 Flodesign Sonics, Inc. Bioreactor using acoustic standing waves
EP3529347A1 (en) * 2016-10-19 2019-08-28 Flodesign Sonics, Inc. Affinity cell extraction by acoustics
CA2994643A1 (en) * 2017-02-14 2018-08-14 Bart Lipkens Bioreactor using acoustic standing waves
WO2018187789A1 (en) * 2017-04-06 2018-10-11 Flodesign Sonics, Inc. Acoustic perfusion devices
CN114900773A (zh) 2017-12-14 2022-08-12 弗洛设计声能学公司 声泳系统及其操作方法、控制声换能器及声学系统的方法
EP3728551A1 (en) * 2017-12-20 2020-10-28 Global Life Sciences Solutions USA LLC Cell harvesting and isolation
JP7091861B2 (ja) 2018-01-17 2022-06-28 株式会社Ihi 細胞培養システム及び細胞培養方法
JP7087704B2 (ja) 2018-06-13 2022-06-21 株式会社Ihi 細胞培養システム及び細胞培養方法
US11028359B2 (en) * 2018-09-11 2021-06-08 Global Life Sciences Solutions Usa Llc Separation devices, associated methods, and systems
WO2020088180A1 (en) * 2018-11-02 2020-05-07 Wuxi Biologics (Shanghai) Co., Ltd. Cell culture process by intensified perfusion with continuous harvest and without cell bleeding
BR112021013791A2 (pt) * 2019-01-21 2021-09-21 Flodesign Sonics, Inc. Parâmetros para concentração e lavagem de partículas com acústica
US20230031710A1 (en) * 2020-01-07 2023-02-02 Cytiva Sweden Ab Systems and method for controlling fluid flow in bioreactors
EP4182427A1 (en) 2020-07-15 2023-05-24 Global Life Sciences Solutions USA LLC Bioprocessing perfusion system having a plurality of filters and method of operating the same
CN116249884A (zh) * 2020-11-11 2023-06-09 深圳汇芯生物医疗科技有限公司 分离芯片组件
CN115449482A (zh) * 2021-06-09 2022-12-09 佛山汉腾生物科技有限公司 一种细胞培养设备、细胞培养方法
WO2024218715A1 (en) 2023-04-19 2024-10-24 Btl Healthcare Technologies A.S. Culture media based on protein hydrolysate and a process for preparing thereof
US12668774B2 (en) 2023-10-12 2026-06-30 Btl Healthcare Technologies A.S. Product, system and method of cell cultivation

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT389235B (de) * 1987-05-19 1989-11-10 Stuckart Wolfgang Verfahren zur reinigung von fluessigkeiten mittels ultraschall und vorrichtungen zur durchfuehrung dieses verfahrens
JP3078067B2 (ja) * 1991-11-14 2000-08-21 ユニチカ株式会社 耐熱性アデノシン−5’−3リン酸スルフリラーゼ及びその製造法
US5626767A (en) * 1993-07-02 1997-05-06 Sonosep Biotech Inc. Acoustic filter for separating and recycling suspended particles
US5503750A (en) * 1993-10-04 1996-04-02 Russo, Jr.; Lawrence J. Membrane-based process for the recovery of lactic acid by fermentation of carbohydrate substrates containing sugars
US5951456A (en) * 1997-05-16 1999-09-14 Scott; Harold W. Ultrasonic methods and apparatus for separating materials in a fluid mixture
JPH11326155A (ja) * 1998-05-20 1999-11-26 Hitachi Ltd 細胞分画装置
KR20010024864A (ko) * 1998-11-20 2001-03-26 도시가주 모리 액체처리 방법 및 액체처리 장치 및 액체처리 시스템
EP1175931A1 (en) * 2000-07-25 2002-01-30 Computer Cell Culture Center S.A. Integration of high cell density bioreactor operation with ultra fast on-line downstream processing
EP1354941A1 (en) * 2002-04-19 2003-10-22 Computer Cell Culture Center S.A. Apparatus and method for a cell culture in a bioreactor at high cell concentration
US6749666B2 (en) * 2002-04-26 2004-06-15 Board Of Regents, The University Of Texas System Modulated acoustic aggiomeration system and method
US9109193B2 (en) * 2007-07-30 2015-08-18 Ge Healthcare Bio-Sciences Corp. Continuous perfusion bioreactor system
WO2009023562A2 (en) * 2007-08-09 2009-02-19 Wyeth Use of perfusion to enhance production of fed-batch cell culture in bioreactors
US9011699B2 (en) * 2010-08-23 2015-04-21 Flodesign Sonics, Inc. Ultrasonic agglomeration of microalgae
KR101251191B1 (ko) * 2010-11-04 2013-04-08 김성천 세포배양을 통한 세포 및 지용성물질의 생산 방법 및 장치
JP5926747B2 (ja) * 2011-02-24 2016-05-25 ジーイー・ヘルスケア・バイオサイエンス・アクチボラグ フィルターアセンブリを通る供給流及び回収流を有するバイオリアクター
WO2013109520A1 (en) * 2012-01-18 2013-07-25 Bayer Healthcare Llc Perfusion bioreactor systems and methods of operating the same
US9416344B2 (en) * 2012-03-15 2016-08-16 Flodesign Sonics, Inc. Bioreactor using acoustic standing waves
US8980596B2 (en) * 2012-05-23 2015-03-17 Lanzatech New Zealand Limited Fermentation and simulated moving bed process

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