JP2017502666A5 - - Google Patents

Download PDF

Info

Publication number
JP2017502666A5
JP2017502666A5 JP2016542737A JP2016542737A JP2017502666A5 JP 2017502666 A5 JP2017502666 A5 JP 2017502666A5 JP 2016542737 A JP2016542737 A JP 2016542737A JP 2016542737 A JP2016542737 A JP 2016542737A JP 2017502666 A5 JP2017502666 A5 JP 2017502666A5
Authority
JP
Japan
Prior art keywords
bioreactor
standing wave
acoustic standing
cell separator
fluid communication
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2016542737A
Other languages
English (en)
Japanese (ja)
Other versions
JP2017502666A (ja
JP6896242B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/SE2014/051575 external-priority patent/WO2015102528A1/en
Publication of JP2017502666A publication Critical patent/JP2017502666A/ja
Publication of JP2017502666A5 publication Critical patent/JP2017502666A5/ja
Application granted granted Critical
Publication of JP6896242B2 publication Critical patent/JP6896242B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2016542737A 2013-12-30 2014-12-29 細胞培養のための装置 Expired - Fee Related JP6896242B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361921626P 2013-12-30 2013-12-30
US61/921,626 2013-12-30
US201461983482P 2014-04-24 2014-04-24
US61/983,482 2014-04-24
PCT/SE2014/051575 WO2015102528A1 (en) 2013-12-30 2014-12-29 Apparatus for cell cultivation

Publications (3)

Publication Number Publication Date
JP2017502666A JP2017502666A (ja) 2017-01-26
JP2017502666A5 true JP2017502666A5 (enExample) 2018-02-15
JP6896242B2 JP6896242B2 (ja) 2021-06-30

Family

ID=53493759

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016542737A Expired - Fee Related JP6896242B2 (ja) 2013-12-30 2014-12-29 細胞培養のための装置

Country Status (4)

Country Link
US (2) US20160312168A1 (enExample)
EP (1) EP3089800A4 (enExample)
JP (1) JP6896242B2 (enExample)
WO (1) WO2015102528A1 (enExample)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8691145B2 (en) 2009-11-16 2014-04-08 Flodesign Sonics, Inc. Ultrasound and acoustophoresis for water purification
US9752114B2 (en) 2012-03-15 2017-09-05 Flodesign Sonics, Inc Bioreactor using acoustic standing waves
US9745548B2 (en) 2012-03-15 2017-08-29 Flodesign Sonics, Inc. Acoustic perfusion devices
US9458450B2 (en) 2012-03-15 2016-10-04 Flodesign Sonics, Inc. Acoustophoretic separation technology using multi-dimensional standing waves
US10704021B2 (en) 2012-03-15 2020-07-07 Flodesign Sonics, Inc. Acoustic perfusion devices
US9752113B2 (en) 2012-03-15 2017-09-05 Flodesign Sonics, Inc. Acoustic perfusion devices
US9783775B2 (en) 2012-03-15 2017-10-10 Flodesign Sonics, Inc. Bioreactor using acoustic standing waves
US9796956B2 (en) 2013-11-06 2017-10-24 Flodesign Sonics, Inc. Multi-stage acoustophoresis device
US10689609B2 (en) 2012-03-15 2020-06-23 Flodesign Sonics, Inc. Acoustic bioreactor processes
US9272234B2 (en) 2012-03-15 2016-03-01 Flodesign Sonics, Inc. Separation of multi-component fluid through ultrasonic acoustophoresis
US10967298B2 (en) 2012-03-15 2021-04-06 Flodesign Sonics, Inc. Driver and control for variable impedence load
US10953436B2 (en) 2012-03-15 2021-03-23 Flodesign Sonics, Inc. Acoustophoretic device with piezoelectric transducer array
US10322949B2 (en) 2012-03-15 2019-06-18 Flodesign Sonics, Inc. Transducer and reflector configurations for an acoustophoretic device
US9567559B2 (en) 2012-03-15 2017-02-14 Flodesign Sonics, Inc. Bioreactor using acoustic standing waves
US10370635B2 (en) 2012-03-15 2019-08-06 Flodesign Sonics, Inc. Acoustic separation of T cells
US9950282B2 (en) 2012-03-15 2018-04-24 Flodesign Sonics, Inc. Electronic configuration and control for acoustic standing wave generation
US10737953B2 (en) 2012-04-20 2020-08-11 Flodesign Sonics, Inc. Acoustophoretic method for use in bioreactors
US9745569B2 (en) 2013-09-13 2017-08-29 Flodesign Sonics, Inc. System for generating high concentration factors for low cell density suspensions
CA2935960C (en) 2014-01-08 2023-01-10 Bart Lipkens Acoustophoresis device with dual acoustophoretic chamber
US9744483B2 (en) 2014-07-02 2017-08-29 Flodesign Sonics, Inc. Large scale acoustic separation device
US9944894B2 (en) 2015-01-16 2018-04-17 General Electric Company Pluripotent stem cell expansion and passage using a rocking platform bioreactor
US10106770B2 (en) 2015-03-24 2018-10-23 Flodesign Sonics, Inc. Methods and apparatus for particle aggregation using acoustic standing waves
US11377651B2 (en) 2016-10-19 2022-07-05 Flodesign Sonics, Inc. Cell therapy processes utilizing acoustophoresis
US11021699B2 (en) 2015-04-29 2021-06-01 FioDesign Sonics, Inc. Separation using angled acoustic waves
US11708572B2 (en) 2015-04-29 2023-07-25 Flodesign Sonics, Inc. Acoustic cell separation techniques and processes
US11474085B2 (en) 2015-07-28 2022-10-18 Flodesign Sonics, Inc. Expanded bed affinity selection
US11459540B2 (en) 2015-07-28 2022-10-04 Flodesign Sonics, Inc. Expanded bed affinity selection
SG11201809051YA (en) * 2016-04-15 2018-11-29 Boehringer Ingelheim Int Cell retention device and method
US10710006B2 (en) 2016-04-25 2020-07-14 Flodesign Sonics, Inc. Piezoelectric transducer for generation of an acoustic standing wave
US11214789B2 (en) 2016-05-03 2022-01-04 Flodesign Sonics, Inc. Concentration and washing of particles with acoustics
CN114891635A (zh) 2016-05-03 2022-08-12 弗洛设计声能学公司 利用声泳的治疗细胞洗涤、浓缩和分离
US11085035B2 (en) 2016-05-03 2021-08-10 Flodesign Sonics, Inc. Therapeutic cell washing, concentration, and separation utilizing acoustophoresis
CA3034208A1 (en) * 2016-08-16 2018-02-22 Flodesign Sonics, Inc. Bioreactor using acoustic standing waves
CN110494543A (zh) * 2016-10-19 2019-11-22 弗洛设计声能学公司 通过声学的亲和细胞提取
CA2994643A1 (en) * 2017-02-14 2018-08-14 Bart Lipkens Bioreactor using acoustic standing waves
SG11202003765RA (en) * 2017-04-06 2020-05-28 Flodesign Sonics Inc Acoustic perfusion devices
KR20220066413A (ko) 2017-12-14 2022-05-24 프로디자인 소닉스, 인크. 음향 트랜스듀서 구동기 및 제어기
US11905508B2 (en) * 2017-12-20 2024-02-20 Global Life Sciences Solutions Usa Llc Cell harvesting and isolation
JP7091861B2 (ja) 2018-01-17 2022-06-28 株式会社Ihi 細胞培養システム及び細胞培養方法
JP7087704B2 (ja) 2018-06-13 2022-06-21 株式会社Ihi 細胞培養システム及び細胞培養方法
US11028359B2 (en) * 2018-09-11 2021-06-08 Global Life Sciences Solutions Usa Llc Separation devices, associated methods, and systems
US20220364034A1 (en) * 2018-11-02 2022-11-17 WuXi Biologics Ireland Limited Cell culture process by intensified perfusion with continuous harvest and without cell bleeding
WO2020154334A1 (en) * 2019-01-21 2020-07-30 Flodesign Sonics, Inc. Parameters for concentration and washing of particles with acoustics
CN114867837A (zh) * 2020-01-07 2022-08-05 思拓凡瑞典有限公司 用于控制生物反应器中流体流的系统和方法
KR102835183B1 (ko) * 2020-11-11 2025-07-17 센젠 후이신 라이프 테크놀로지스 컴퍼니 리미티드 분리 칩 조립체
CN115449482A (zh) * 2021-06-09 2022-12-09 佛山汉腾生物科技有限公司 一种细胞培养设备、细胞培养方法

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT389235B (de) * 1987-05-19 1989-11-10 Stuckart Wolfgang Verfahren zur reinigung von fluessigkeiten mittels ultraschall und vorrichtungen zur durchfuehrung dieses verfahrens
JP3078067B2 (ja) * 1991-11-14 2000-08-21 ユニチカ株式会社 耐熱性アデノシン−5’−3リン酸スルフリラーゼ及びその製造法
US5626767A (en) * 1993-07-02 1997-05-06 Sonosep Biotech Inc. Acoustic filter for separating and recycling suspended particles
US5503750A (en) * 1993-10-04 1996-04-02 Russo, Jr.; Lawrence J. Membrane-based process for the recovery of lactic acid by fermentation of carbohydrate substrates containing sugars
US5951456A (en) * 1997-05-16 1999-09-14 Scott; Harold W. Ultrasonic methods and apparatus for separating materials in a fluid mixture
JPH11326155A (ja) * 1998-05-20 1999-11-26 Hitachi Ltd 細胞分画装置
EP1057785A1 (en) * 1998-11-20 2000-12-06 Proudo Co., Ltd. Method of treating liquid, liquid treatment apparatus, and liquid treatment system
EP1175931A1 (en) * 2000-07-25 2002-01-30 Computer Cell Culture Center S.A. Integration of high cell density bioreactor operation with ultra fast on-line downstream processing
EP1354941A1 (en) * 2002-04-19 2003-10-22 Computer Cell Culture Center S.A. Apparatus and method for a cell culture in a bioreactor at high cell concentration
US6749666B2 (en) * 2002-04-26 2004-06-15 Board Of Regents, The University Of Texas System Modulated acoustic aggiomeration system and method
US9109193B2 (en) * 2007-07-30 2015-08-18 Ge Healthcare Bio-Sciences Corp. Continuous perfusion bioreactor system
EP3327132A3 (en) * 2007-08-09 2018-07-18 Wyeth LLC Use of perfusion to enhance production of fed-batch cell culture in bioreactors
US9011699B2 (en) * 2010-08-23 2015-04-21 Flodesign Sonics, Inc. Ultrasonic agglomeration of microalgae
KR101251191B1 (ko) * 2010-11-04 2013-04-08 김성천 세포배양을 통한 세포 및 지용성물질의 생산 방법 및 장치
CN103380210B (zh) * 2011-02-24 2016-11-09 通用电气健康护理生物科学股份公司 具有通过过滤组件的给料流和收获流的生物反应器
CN104160013B (zh) * 2012-01-18 2017-07-28 拜尔健康护理有限责任公司 灌流式生物反应器系统及操作其的方法
US9416344B2 (en) * 2012-03-15 2016-08-16 Flodesign Sonics, Inc. Bioreactor using acoustic standing waves
WO2013177466A1 (en) * 2012-05-23 2013-11-28 Lanzatech New Zealand Limited A fermentation and simulated moving bed process

Similar Documents

Publication Publication Date Title
JP2017502666A5 (enExample)
JP6896242B2 (ja) 細胞培養のための装置
CN110997893B (zh) 用于灌注应用的切向流过滤设备
US9752114B2 (en) Bioreactor using acoustic standing waves
US9550016B2 (en) Passive separation of whole blood
US20170191022A1 (en) Bioreactor using acoustic standing waves
US10518196B2 (en) Devices for separation of particulates, associated methods and systems
KR20180019753A (ko) 잔류물의 재순환을 이용한 싱글 패스 접선 유동 여과 시스템 및 접선 유동 여과 시스템
CN105592913B (zh) 用于使用单程切向流过滤系统和具有渗余物的再循环的切向流过滤系统过滤液体的方法
WO2012115790A3 (en) Extended area filter
EA201691859A1 (ru) Последовательное удаление газоконденсатных жидкостей из потока природного газа
JP2013538588A5 (enExample)
WO2012149582A3 (en) Concentrator filter
JP2018516579A5 (enExample)
BR112017000545B1 (pt) sistema e método para produção de um composto orgânico de uma fonte de açúcar por fermentação
MA34044B1 (fr) Dispositif pour filtrer et separer des milieux en ecoulement
CN101229531B (zh) 含u型滤网的组合式离心管
RU2014146207A (ru) Отделитель для диоксида углерода, способ его эксплуатации и отделительный узел
KR101791307B1 (ko) 수처리 장치 및 이를 이용한 수처리방법
CN204625401U (zh) 一种用于药品生产的纯净水供给系统
CN206710392U (zh) 一种气质联用仪样品预处理装置
CN203886427U (zh) 一种超滤监测装置
CN206414980U (zh) 一种具有连续式在线加水功能的膜分离系统
JP6637998B2 (ja) フィルム結合型フラットパック
Ahmed et al. Computational modeling for visualization of flow patterns in a membrane testing device