JP2017500279A5 - - Google Patents

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JP2017500279A5
JP2017500279A5 JP2016523932A JP2016523932A JP2017500279A5 JP 2017500279 A5 JP2017500279 A5 JP 2017500279A5 JP 2016523932 A JP2016523932 A JP 2016523932A JP 2016523932 A JP2016523932 A JP 2016523932A JP 2017500279 A5 JP2017500279 A5 JP 2017500279A5
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channel
well
impedance
region
pressure
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JP2016523932A
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Japanese (ja)
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JP2017500279A (ja
JP6640079B2 (ja
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Priority claimed from PCT/US2014/060961 external-priority patent/WO2015057998A1/en
Publication of JP2017500279A publication Critical patent/JP2017500279A/ja
Publication of JP2017500279A5 publication Critical patent/JP2017500279A5/ja
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JP2016523932A 2013-10-16 2014-10-16 小容積の粒子を調製するためのデバイス及び方法 Active JP6640079B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361891758P 2013-10-16 2013-10-16
US61/891,758 2013-10-16
PCT/US2014/060961 WO2015057998A1 (en) 2013-10-16 2014-10-16 Device for formulating particles at small volumes

Publications (3)

Publication Number Publication Date
JP2017500279A JP2017500279A (ja) 2017-01-05
JP2017500279A5 true JP2017500279A5 (enExample) 2017-11-09
JP6640079B2 JP6640079B2 (ja) 2020-02-05

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JP2016523932A Active JP6640079B2 (ja) 2013-10-16 2014-10-16 小容積の粒子を調製するためのデバイス及び方法

Country Status (6)

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US (2) US10159652B2 (enExample)
EP (1) EP3057693A4 (enExample)
JP (1) JP6640079B2 (enExample)
CN (1) CN105813721B (enExample)
CA (1) CA2927358C (enExample)
WO (1) WO2015057998A1 (enExample)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6764870B2 (ja) 2015-02-24 2020-10-07 ザ・ユニバーシティ・オブ・ブリティッシュ・コロンビア 連続フローマイクロ流体システム
WO2016165825A1 (en) 2015-04-13 2016-10-20 Curevac Ag Method for producing rna compositions
JP2018525209A (ja) 2015-04-28 2018-09-06 ザ・ユニバーシティ・オブ・ブリティッシュ・コロンビア 使い捨てマイクロ流体カートリッジ
USD771833S1 (en) 2015-04-28 2016-11-15 University Of British Columbia Microfluidic cartridge
USD771834S1 (en) 2015-04-28 2016-11-15 University Of British Columbia Microfluidic cartridge
USD772427S1 (en) 2015-04-28 2016-11-22 University Of British Columbia Microfluidic cartridge
WO2017048770A1 (en) * 2015-09-15 2017-03-23 Regulus Therapeutics, Inc. Systems, compositions, and methods for formulating nucleic acid compositions
JP7349788B2 (ja) * 2016-01-06 2023-09-25 ザ・ユニバーシティ・オブ・ブリティッシュ・コロンビア 分岐ミキサー並びにその使用及び製造方法
CA3027643C (en) 2016-07-06 2021-01-19 Precision Nanosystems Inc Smart microfluidic mixing instrument and cartridges
WO2018064755A1 (en) * 2016-10-03 2018-04-12 Precision Nanosystems Inc. Compositions for transfecting resistant cell types
US11938456B2 (en) 2016-12-16 2024-03-26 Delphi Scientific, Llc Layered particles and processes thereof
WO2019139997A1 (en) * 2018-01-09 2019-07-18 Trucode Gene Repair, Inc. Polymer-based nanoparticles, related formulation methods, and apparatus
CA3097203C (en) * 2018-04-29 2023-09-05 Precision Nanosystems Inc. Compositions for transfecting resistant cell types
AU2019362031A1 (en) * 2018-10-19 2021-04-08 Translate Bio, Inc. Pumpless encapsulation of messenger RNA
AU2020260280B2 (en) * 2019-04-15 2023-06-29 Global Life Sciences Solutions Canada Ulc Nonviral modification of t cell gene expression
TWI851862B (zh) * 2019-12-23 2024-08-11 美商胡桃夾子治療公司 微流體裝置及其使用方法
AU2021252164A1 (en) 2020-04-09 2022-12-15 Finncure Oy Mimetic nanoparticles for preventing the spreading and lowering the infection rate of novel coronaviruses
US12194157B2 (en) 2020-04-09 2025-01-14 Finncure Oy Carrier for targeted delivery to a host
DE102020214601A1 (de) * 2020-11-19 2022-05-19 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung eingetragener Verein Verfahren und Vorrichtung zur Herstellung einer Flüssigkeit enthaltend Liposomen und hergestellte Flüssigkeit
CN116887910A (zh) 2020-11-30 2023-10-13 精密纳米系统无限责任公司 非聚集微流体混合器和用于其的方法
CN114247398A (zh) * 2021-12-17 2022-03-29 沈磊 一种脂质纳米颗粒制备系统及设备
WO2024006863A1 (en) 2022-06-30 2024-01-04 Precision NanoSystems ULC Lipid nanoparticle formulations for vaccines
KR20250120406A (ko) 2022-12-12 2025-08-08 글로벌 라이프 사이언시즈 솔루션즈 캐나다 유엘씨 지질 나노입자 동결건조 방법 및 조성물
WO2025005990A1 (en) 2023-06-28 2025-01-02 Global Life Sciences Solutions Canada Ulc Lipid nanoparticle formulations for cell therapy and related methods
WO2025049579A1 (en) 2023-08-31 2025-03-06 Global Life Sciences Solutions Canada Ulc Intranasal formulation for pulmonary delivery of nanoparticles, compositions, uses, and manufacturing methods thereof
WO2025219528A1 (en) 2024-04-17 2025-10-23 Global Life Sciences Solutions Canada Ulc Non-destructive plasmid delivery to immune cells
WO2025219491A1 (en) 2024-04-17 2025-10-23 Global Life Sciences Solutions Canada Ulc Method and composition for hdr template dna delivery

Family Cites Families (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4469863A (en) 1980-11-12 1984-09-04 Ts O Paul O P Nonionic nucleic acid alkyl and aryl phosphonates and processes for manufacture and use thereof
US5034506A (en) 1985-03-15 1991-07-23 Anti-Gene Development Group Uncharged morpholino-based polymers having achiral intersubunit linkages
US5235033A (en) 1985-03-15 1993-08-10 Anti-Gene Development Group Alpha-morpholino ribonucleoside derivatives and polymers thereof
US5216141A (en) 1988-06-06 1993-06-01 Benner Steven A Oligonucleotide analogs containing sulfur linkages
JP3119871B2 (ja) 1990-07-26 2000-12-25 株式会社医薬分子設計研究所 オリゴデオキシリボヌクレオチド類
US5602240A (en) 1990-07-27 1997-02-11 Ciba Geigy Ag. Backbone modified oligonucleotide analogs
US5386023A (en) 1990-07-27 1995-01-31 Isis Pharmaceuticals Backbone modified oligonucleotide analogs and preparation thereof through reductive coupling
US5432272A (en) 1990-10-09 1995-07-11 Benner; Steven A. Method for incorporating into a DNA or RNA oligonucleotide using nucleotides bearing heterocyclic bases
DK51092D0 (da) 1991-05-24 1992-04-15 Ole Buchardt Oligonucleotid-analoge betegnet pna, monomere synthoner og fremgangsmaade til fremstilling deraf samt anvendelser deraf
US5766855A (en) 1991-05-24 1998-06-16 Buchardt, Deceased; Ole Peptide nucleic acids having enhanced binding affinity and sequence specificity
US5539082A (en) 1993-04-26 1996-07-23 Nielsen; Peter E. Peptide nucleic acids
US5714331A (en) 1991-05-24 1998-02-03 Buchardt, Deceased; Ole Peptide nucleic acids having enhanced binding affinity, sequence specificity and solubility
US5641625A (en) 1992-05-22 1997-06-24 Isis Pharmaceuticals, Inc. Cleaving double-stranded DNA with peptide nucleic acids
US5719262A (en) 1993-11-22 1998-02-17 Buchardt, Deceased; Ole Peptide nucleic acids having amino acid side chains
US5644048A (en) 1992-01-10 1997-07-01 Isis Pharmaceuticals, Inc. Process for preparing phosphorothioate oligonucleotides
GB9211979D0 (en) 1992-06-05 1992-07-15 Buchard Ole Uses of nucleic acid analogues
US5417956A (en) * 1992-08-18 1995-05-23 Worcester Polytechnic Institute Preparation of nanophase solid state materials
US5527675A (en) 1993-08-20 1996-06-18 Millipore Corporation Method for degradation and sequencing of polymers which sequentially eliminate terminal residues
DE4331012A1 (de) 1993-09-13 1995-03-16 Bayer Ag Nukleinsäuren-bindende Oligomere mit N-Verzweigung für Therapie und Diagnostik
GB2284209A (en) 1993-11-25 1995-05-31 Ole Buchardt Nucleic acid analogue-induced transcription of RNA from a double-stranded DNA template
US5637684A (en) 1994-02-23 1997-06-10 Isis Pharmaceuticals, Inc. Phosphoramidate and phosphorothioamidate oligomeric compounds
US5705333A (en) 1994-08-05 1998-01-06 The Regents Of The University Of California Peptide-based nucleic acid mimics(PENAMS)
US5753789A (en) 1996-07-26 1998-05-19 Yale University Oligonucleotides containing L-nucleosides
US6043060A (en) 1996-11-18 2000-03-28 Imanishi; Takeshi Nucleotide analogues
JP3756313B2 (ja) 1997-03-07 2006-03-15 武 今西 新規ビシクロヌクレオシド及びオリゴヌクレオチド類縁体
US6251666B1 (en) 1997-03-31 2001-06-26 Ribozyme Pharmaceuticals, Inc. Nucleic acid catalysts comprising L-nucleotide analogs
US6107470A (en) 1997-05-29 2000-08-22 Nielsen; Peter E. Histidine-containing peptide nucleic acids
KR100414936B1 (ko) 1997-09-12 2004-01-13 엑시콘 에이/에스 이환 및 삼환 뉴클레오시드, 뉴클레오타이드 및올리고뉴클레오타이드 동족체
KR100694914B1 (ko) 1998-07-09 2007-03-14 바이오셉트 인코포레이티드 디엔에이 서열 하이브리드화를 최적화하기 위한 개선된펩티드 핵산 유니버셜 라이브러리의 사용방법
JP2002026134A (ja) 2000-07-12 2002-01-25 Seiko Epson Corp 半導体集積回路の製造方法及びこの方法により製造した半導体集積回路
WO2003011443A2 (en) 2001-07-27 2003-02-13 President And Fellows Of Harvard College Laminar mixing apparatus and methods
GB0126716D0 (en) * 2001-11-07 2002-01-02 Advanced Phytonics Ltd Method for the production of particles
JP3775305B2 (ja) * 2002-01-31 2006-05-17 コニカミノルタホールディングス株式会社 液体混合機構及び液体混合方法
US7718099B2 (en) 2002-04-25 2010-05-18 Tosoh Corporation Fine channel device, fine particle producing method and solvent extraction method
EP1391237B1 (en) 2002-08-01 2011-09-21 Tosoh Corporation Fine channel device, desksize chemical plant and fine particle producing apparatus employing them
JP2006527093A (ja) * 2003-03-10 2006-11-30 ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン プログラム可能な触覚アクチュエータを用いた集積化したマイクロ流体コントロール
JP4346456B2 (ja) 2004-01-19 2009-10-21 株式会社Ｋｒｉ 微粒子製造装置
GB0418447D0 (en) * 2004-08-19 2004-09-22 Advanced Phytonics Ltd Process for preparing particles and apparatus
JP4822689B2 (ja) * 2004-10-29 2011-11-24 株式会社Ｋｒｉ 微生物単離装置、微生物の単離方法および該方法で得られた微生物含有微粒子
JP4713397B2 (ja) * 2006-01-18 2011-06-29 株式会社リコー 微小流路構造体及び微小液滴生成システム
WO2007150030A2 (en) * 2006-06-23 2007-12-27 Massachusetts Institute Of Technology Microfluidic synthesis of organic nanoparticles
US7985388B2 (en) * 2006-10-02 2011-07-26 Nanomaterials Technology Pte Ltd Process for making nano-sized and micro-sized precipitate particles
JP5823405B2 (ja) 2009-11-04 2015-11-25 ザ ユニバーシティ オブ ブリティッシュ コロンビア 核酸含有脂質粒子および関連方法
US20130323269A1 (en) 2010-07-30 2013-12-05 Muthiah Manoharan Methods and compositions for delivery of active agents

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