JP2017500123A5 - - Google Patents

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JP2017500123A5
JP2017500123A5 JP2016541160A JP2016541160A JP2017500123A5 JP 2017500123 A5 JP2017500123 A5 JP 2017500123A5 JP 2016541160 A JP2016541160 A JP 2016541160A JP 2016541160 A JP2016541160 A JP 2016541160A JP 2017500123 A5 JP2017500123 A5 JP 2017500123A5
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JP
Japan
Prior art keywords
inner tube
treatment device
retinal
retinal treatment
retina
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JP2016541160A
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English (en)
Japanese (ja)
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JP2017500123A (ja
JP6438030B2 (ja
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Priority claimed from US14/132,859 external-priority patent/US10010447B2/en
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JP2016541160A 2013-12-18 2014-11-06 治療薬の網膜下の送達のためのシステム Active JP6438030B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14/132,859 2013-12-18
US14/132,859 US10010447B2 (en) 2013-12-18 2013-12-18 Systems and methods for subretinal delivery of therapeutic agents
PCT/US2014/064407 WO2015094507A1 (en) 2013-12-18 2014-11-06 Systems and methods for subretinal delivery of therapeutic agents

Publications (3)

Publication Number Publication Date
JP2017500123A JP2017500123A (ja) 2017-01-05
JP2017500123A5 true JP2017500123A5 (cg-RX-API-DMAC7.html) 2017-11-16
JP6438030B2 JP6438030B2 (ja) 2018-12-12

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ID=53367065

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JP2016541160A Active JP6438030B2 (ja) 2013-12-18 2014-11-06 治療薬の網膜下の送達のためのシステム

Country Status (8)

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US (1) US10010447B2 (cg-RX-API-DMAC7.html)
EP (1) EP3068353B1 (cg-RX-API-DMAC7.html)
JP (1) JP6438030B2 (cg-RX-API-DMAC7.html)
CN (1) CN105979914B (cg-RX-API-DMAC7.html)
AU (1) AU2014367150C1 (cg-RX-API-DMAC7.html)
CA (1) CA2932912C (cg-RX-API-DMAC7.html)
ES (1) ES2733398T3 (cg-RX-API-DMAC7.html)
WO (1) WO2015094507A1 (cg-RX-API-DMAC7.html)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9730834B2 (en) * 2013-12-20 2017-08-15 Novartis Ag Variable stiffness cannula and methods for a surgical system
US9925088B2 (en) * 2014-06-06 2018-03-27 Janssen Biotech, Inc. Sub-retinal tangential needle catheter guide and introducer
US20160331584A1 (en) * 2015-05-14 2016-11-17 Novartis Ag Surgical tool tracking to control surgical system
US10507134B2 (en) 2015-05-27 2019-12-17 Novartis Ag Systems and methods for pulsed posterior vitreous detachment creation
AU2016372824B2 (en) 2015-12-14 2021-05-20 Alcon Inc. Uni-port hybrid gauge surgical apparatuses and methods
WO2017103744A1 (en) * 2015-12-14 2017-06-22 Novartis Ag Patch for sealing retinal breaks and associated devices, systems, and methods
TW201722377A (zh) 2015-12-16 2017-07-01 諾華公司 用於插管遞送式治療材料施加裝置之裝置及方法
US10478553B2 (en) * 2016-03-09 2019-11-19 Orbit Biomedical Limited Apparatus for subretinal administration of therapeutic agent via a curved needle
US10646374B2 (en) * 2016-06-17 2020-05-12 Orbit Biomedical Limited Apparatus and method to form entry bleb for subretinal delivery of therapeutic agent
US11033427B2 (en) 2017-04-13 2021-06-15 Alcon Inc. Vitreoretinal instruments for fluid aspiration
WO2019082082A1 (en) * 2017-10-27 2019-05-02 Novartis Ag OCT DISPLAY CONTROLLED BY LEVER OF FOOT CONTROL FOR VITREO-RETINAL SURGERY
US11433174B2 (en) * 2018-12-12 2022-09-06 Alcon Inc. Retractable backflush instrument
US12318343B2 (en) 2019-05-29 2025-06-03 Alcon Inc. Retina massage and smoothing device
DE102020115346A1 (de) * 2020-06-09 2021-12-09 Carl Zeiss Meditec Ag Kontrollierte Injektion zwischen zwei Gewebeschichten des menschlichen Auges
TWI757205B (zh) * 2020-06-30 2022-03-01 財團法人工業技術研究院 微針電轉染裝置
AU2021360288A1 (en) * 2020-10-15 2023-05-11 Alcon Inc. Wireless injector
CA3201659A1 (en) * 2020-12-17 2022-06-23 Reto GRUEEBLER A retractable backflush instrument
CA3204137A1 (en) 2021-01-25 2022-07-28 Niels Alexander Abt Method and apparatus for subretinal injection
JP6964912B1 (ja) * 2021-05-28 2021-11-10 株式会社中京メディカル 眼球装着管
US20240350312A1 (en) * 2021-08-10 2024-10-24 Nallakrishnan Family Trust Surgical Instrument And Method For Goniotomy Procedure
WO2024013559A1 (en) * 2022-07-11 2024-01-18 Gyroscope Therapeutics Limited Transvitreal subretinal injector
CN119770839B (zh) * 2025-03-11 2025-07-04 瑞安市人民医院(瑞安市人民医院医疗服务集团瑞安市红十字医院) 一种食道精准上药器

Family Cites Families (118)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4830877B1 (cg-RX-API-DMAC7.html) * 1966-11-25 1973-09-25
US5164188A (en) 1989-11-22 1992-11-17 Visionex, Inc. Biodegradable ocular implants
US5084009A (en) * 1990-04-18 1992-01-28 Mackool Richard J Fluid infusion sleeve for use during eye surgery
US5273530A (en) 1990-11-14 1993-12-28 The University Of Rochester Intraretinal delivery and withdrawal instruments
US5767079A (en) 1992-07-08 1998-06-16 Celtrix Pharmaceuticals, Inc. Method of treating ophthalmic disorders using TGF -β
CA2150554A1 (en) 1992-12-02 1994-06-09 Sheng-Wan Tsao Cyclodextrin and polymer based drug delivery system
US5399352A (en) 1993-04-14 1995-03-21 Emory University Device for local drug delivery and methods for using the same
US5985307A (en) 1993-04-14 1999-11-16 Emory University Device and method for non-occlusive localized drug delivery
WO1995003009A1 (en) 1993-07-22 1995-02-02 Oculex Pharmaceuticals, Inc. Method of treatment of macular degeneration
US5443505A (en) 1993-11-15 1995-08-22 Oculex Pharmaceuticals, Inc. Biocompatible ocular implants
WO1995017673A1 (en) 1993-12-21 1995-06-29 Ocutech, Inc. Ocular diagnostics and therapies
SE9402816D0 (sv) 1994-08-24 1994-08-24 Pharmacia Ab Method and meams for drug administration
AU3584895A (en) 1994-09-28 1996-04-19 Celtrix Pharmaceuticals, Inc. Method of treating macular degeneration using tgf-beta
US5899882A (en) 1994-10-27 1999-05-04 Novoste Corporation Catheter apparatus for radiation treatment of a desired area in the vascular system of a patient
CN1177919A (zh) * 1995-03-10 1998-04-01 托马斯·J·钱伯斯 柔性眼内晶状体插入系统
US5755700A (en) * 1995-07-27 1998-05-26 Michiel S. Kritzinger Corneal irrigation cannula and method of using
US6015403A (en) 1996-02-26 2000-01-18 Alcon Laboratories, Inc. Ophthalmic surgery probe with soft tip
US5948427A (en) 1996-04-25 1999-09-07 Point Medical Corporation Microparticulate surgical adhesive
US5941250A (en) * 1996-11-21 1999-08-24 University Of Louisville Research Foundation Inc. Retinal tissue implantation method
HUP0003393A3 (en) 1997-05-16 2001-03-28 Amgen Inc Thousand Oaks Ustained-release delayed gels
AU743819B2 (en) 1997-10-27 2002-02-07 California Institute Of Technology Methods and pharmaceutical compositions for the closure of retinal breaks
US6764461B2 (en) * 1997-12-01 2004-07-20 Scimed Life Systems, Inc. Catheter system for the delivery of a low volume bolus
US7344499B1 (en) 1998-06-10 2008-03-18 Georgia Tech Research Corporation Microneedle device for extraction and sensing of bodily fluids
US6503231B1 (en) 1998-06-10 2003-01-07 Georgia Tech Research Corporation Microneedle device for transport of molecules across tissue
US6936053B1 (en) 1998-07-02 2005-08-30 Jeffrey N. Weiss Ocular implant needle
US6378526B1 (en) 1998-08-03 2002-04-30 Insite Vision, Incorporated Methods of ophthalmic administration
US6309374B1 (en) 1998-08-03 2001-10-30 Insite Vision Incorporated Injection apparatus and method of using same
US6219575B1 (en) 1998-10-23 2001-04-17 Babak Nemati Method and apparatus to enhance optical transparency of biological tissues
JP2002534139A (ja) 1999-01-05 2002-10-15 マサチューセッツ・アイ・アンド・イア・インファーマリー 網膜と脈絡膜への経強膜徐放性薬剤標的送達
JP2003515359A (ja) 1999-02-17 2003-05-07 ボシュ・アンド・ロム・インコーポレイテッド 哺乳類の眼から水晶体を切除する方法、装置およびシステム
EP1178791A2 (en) 1999-05-07 2002-02-13 Johns Hopkins University School of Medicine The use of a protein tyrosine kinase pathway inhibitor in the treatment of ocular disorders
US6159218A (en) * 1999-05-19 2000-12-12 Aramant; Robert B. Retinal tissue implantation tool
US6743211B1 (en) 1999-11-23 2004-06-01 Georgia Tech Research Corporation Devices and methods for enhanced microneedle penetration of biological barriers
JP2003509349A (ja) 1999-09-15 2003-03-11 エラン ファーマシューティカルズ，インコーポレイテッド ヘテロアリールメタンスルホンアミドを使用するニューロパシー性疼痛を処置するための方法。
DE60018777T2 (de) 1999-10-21 2006-02-02 Alcon Inc. Medikamentenversorgung der sub-tenon
WO2001037767A1 (de) * 1999-11-24 2001-05-31 Grieshaber & Co. Ag Einrichtung zum verbessern des kammerwasserabflusses im auge eines lebewesens
KR100855740B1 (ko) 1999-12-10 2008-09-03 아이싸이언스 인터벤셔날 코포레이션 안 질환의 치료방법
US20030211166A1 (en) 2001-07-31 2003-11-13 Yamamoto Ronald K Microparticulate biomaterial composition for medical use
US6491670B1 (en) 2000-04-04 2002-12-10 Duke University Miniaturized surgical instruments especially useful for the opthalmologic surgical procedures and methods of making the same
AU2001259085A1 (en) 2000-04-17 2001-10-30 Childrens Hospital Research Foundation Treatment of ocular neovascularization and related diseases
ATE363902T1 (de) 2000-06-14 2007-06-15 Us Health Isoflavonen gegen strahlungsinduzierte mortalität
US7331944B2 (en) * 2000-10-23 2008-02-19 Medical Instill Technologies, Inc. Ophthalmic dispenser and associated method
US20030171722A1 (en) 2001-01-04 2003-09-11 Michel Paques Microsurgical injection and/or distending instruments and surgical method and apparatus utilizing same
AU2002240004A1 (en) 2001-01-25 2002-08-06 Philip J. Ferrone Infusion cannula
US6827738B2 (en) * 2001-01-30 2004-12-07 Timothy R. Willis Refractive intraocular implant lens and method
US6945984B2 (en) 2001-08-23 2005-09-20 Alcon Grieshaber Ag Micro surgical instrument
JP4303116B2 (ja) 2001-11-21 2009-07-29 アイサイエンス コーポレイション 眼科マイクロサージャリー装置
US20050089545A1 (en) 2002-02-22 2005-04-28 Mitsuaki Kuwano Drug delivery system for the subconjunctival administration of fine grains
US20050165413A1 (en) 2002-03-22 2005-07-28 Conston Stanley R. Ophthalmic microfiducial device and method for use
CA2492140A1 (en) 2002-07-12 2004-01-22 Iscience Surgical Corporation Ultrasound interfacing device for tissue imaging
WO2004026347A2 (en) 2002-09-17 2004-04-01 Iscience Surgical Corporation Apparatus and method for surgical bypass of aqueous humor
US6899717B2 (en) 2002-09-18 2005-05-31 Allergan, Inc. Methods and apparatus for delivery of ocular implants
CA2498191C (en) 2002-09-18 2012-04-10 Trustees Of The University Of Pennsylvania Method of inhibiting choroidal neovascularization
US20040221855A1 (en) 2002-10-17 2004-11-11 Paul Ashton Methods for monitoring treatment of disease
US7141048B1 (en) 2002-10-17 2006-11-28 Alcon, Inc. Vitreoretinal instrument
US7285107B1 (en) 2002-10-17 2007-10-23 Alcon, Inc. Vitreoretinal instrument
US20060167435A1 (en) 2003-02-18 2006-07-27 Adamis Anthony P Transscleral drug delivery device and related methods
AU2004231968B2 (en) 2003-04-16 2011-02-24 Iscience Surgical Corporation Opthalmic microsurgical instruments
US20050009910A1 (en) 2003-07-10 2005-01-13 Allergan, Inc. Delivery of an active drug to the posterior part of the eye via subconjunctival or periocular delivery of a prodrug
JP4180993B2 (ja) 2003-08-06 2008-11-12 日本化薬株式会社 ガス発生器
JP2007520276A (ja) 2004-01-12 2007-07-26 アイサイエンス・インターベンショナル・コーポレーション 粘性材料のための注入器
AU2011221361A1 (en) 2004-01-23 2011-09-29 Iscience Surgical Corporation Composite Ophthalmic Microcannula
AU2011218623B2 (en) 2004-01-23 2014-01-23 Nova Eye, Inc. Composite Ophthalmic Microcannula
PL1715827T3 (pl) 2004-01-23 2011-07-29 Iscience Interventional Corp Złożona okulistyczna mikrokaniula
US20100173866A1 (en) 2004-04-29 2010-07-08 Iscience Interventional Corporation Apparatus and method for ocular treatment
CA2564840A1 (en) 2004-04-29 2005-11-17 Michael Hee Apparatus and method for ocular treatment
US20080058704A1 (en) 2004-04-29 2008-03-06 Michael Hee Apparatus and Method for Ocular Treatment
EP1740239A4 (en) 2004-04-29 2008-12-03 Iscience Interventional Corp DEVICE AND METHOD FOR THE SURGICAL REINFORCEMENT OF THE DRAINAGE OF AQUEOUS HUMOR
US20050244462A1 (en) 2004-04-30 2005-11-03 Allergan, Inc. Devices and methods for treating a mammalian eye
US9138228B2 (en) 2004-08-11 2015-09-22 Emory University Vascular conduit device and system for implanting
WO2006042252A2 (en) 2004-10-08 2006-04-20 Potentia Pharmeceuticals, Inc. Viral complement control proteins for eye disorders
ATE448826T1 (de) * 2004-12-07 2009-12-15 Cook Inc Einführvorrichtung
EP2215996B1 (en) 2004-12-16 2013-04-03 Iscience Interventional Corporation Ophthalmic implant for treatment of glaucoma
AU2012200785A1 (en) 2004-12-16 2012-03-01 Iscience Interventional Corporation Ophthalmic implant for treatment of glaucoma
JP5388582B2 (ja) 2006-01-17 2014-01-15 トランセンド・メディカル・インコーポレイテッド 薬剤投与処置装置
US20070202186A1 (en) 2006-02-22 2007-08-30 Iscience Interventional Corporation Apparatus and formulations for suprachoroidal drug delivery
US7918814B2 (en) 2006-05-02 2011-04-05 Georgia Tech Research Corporation Method for drug delivery to ocular tissue using microneedle
US8197435B2 (en) 2006-05-02 2012-06-12 Emory University Methods and devices for drug delivery to ocular tissue using microneedle
US20080097335A1 (en) 2006-08-04 2008-04-24 Allergan, Inc. Ocular implant delivery assemblies
US9681947B2 (en) * 2006-10-23 2017-06-20 Novartis Ag Intraocular lens delivery system with temperature control
EP2124857B1 (en) * 2007-01-09 2017-03-29 Fovea Pharmaceuticals Apparatus for intra-ocular injection
EP2111821A4 (en) 2007-02-08 2013-10-23 Kaneka Corp INJECTOR FOR EYES
US20080195135A1 (en) 2007-02-12 2008-08-14 Alcon, Inc. Surgical Probe
US7846123B2 (en) 2007-04-24 2010-12-07 Emory University Conduit device and system for implanting a conduit device in a tissue wall
US8147512B1 (en) 2007-06-06 2012-04-03 Scanlan International, Inc. Dual closing guide for a surgical instrument
US20090036827A1 (en) 2007-07-31 2009-02-05 Karl Cazzini Juxtascleral Drug Delivery and Ocular Implant System
WO2009089409A2 (en) 2008-01-10 2009-07-16 Bausch & Lomb Incorporated Intravitreal injection system having coaxial cannulae and use thereof
WO2009105690A2 (en) * 2008-02-21 2009-08-27 Targeted Genetics Corporation Devices and methods for delivering polynucleotides into retinal cells of the macula and fovea
WO2009120960A2 (en) 2008-03-27 2009-10-01 Iscience Interventional Corporation Microliter injector
US8425473B2 (en) 2009-01-23 2013-04-23 Iscience Interventional Corporation Subretinal access device
US20100191177A1 (en) 2009-01-23 2010-07-29 Iscience Interventional Corporation Device for aspirating fluids
US8057483B2 (en) 2009-02-14 2011-11-15 Ocular Transplantation Llc Subretinal implantation instrument
EP2429607A4 (en) 2009-05-15 2014-01-08 Iscience Interventional Corp METHOD AND DEVICE FOR SUBRETINAL CATHETERIZATION
US8419673B2 (en) * 2009-09-21 2013-04-16 Alcon Research, Ltd. Glaucoma drainage device with pump
WO2011057283A1 (en) 2009-11-09 2011-05-12 Iscience Interventional Corporation Expandable cannula for infusion of fluids
US8177747B2 (en) 2009-12-22 2012-05-15 Alcon Research, Ltd. Method and apparatus for drug delivery
WO2011106781A1 (en) 2010-02-26 2011-09-01 Iscience Interventional Corporation Apparatus for enhancement of aqueous humor drainage from the eye
JP5931847B2 (ja) 2010-03-31 2016-06-08 オキュジェクト， エルエルシー 眼内薬剤送達のためのデバイスおよび方法
US9408746B2 (en) 2010-03-31 2016-08-09 Ocuject, Llc Device and method for intraocular drug delivery
US8702644B2 (en) * 2010-05-13 2014-04-22 Ethicon Endo-Surgery, Inc. Instrument for debriding tissue and applying therapeutic cells
JP2013526969A (ja) 2010-05-27 2013-06-27 アイサイエンス・インターベンショナル・コーポレーション シュレム管内に管状インプラントを配置するための装置
EP2588011B1 (en) * 2010-06-30 2015-08-12 Laurimed, Llc Devices for cutting and evacuating tissue
ES2626182T3 (es) 2010-07-21 2017-07-24 Eastern Virginia Medical School Compuestos peptídicos para regular el sistema del complemento
US8821135B2 (en) 2010-08-25 2014-09-02 Emory University Devices and systems for medical fluid treatment
US20120271272A1 (en) * 2010-10-15 2012-10-25 Iscience Interventional Corporation Device for ocular access
US8535268B2 (en) 2010-12-22 2013-09-17 Alcon Research, Ltd. Device for at least one of injection or aspiration
EP2670346A2 (en) 2011-02-01 2013-12-11 Georgia Tech Research Corporation Systems for implanting and using a conduit within a tissue wall
US20120322144A1 (en) 2011-06-14 2012-12-20 Emory University Microfluidic devices and systems
US20130149214A1 (en) 2011-12-12 2013-06-13 Emory University Microvascular fluidic devices, systems and methods related thereto
US9101444B2 (en) * 2012-01-12 2015-08-11 Innfocus, Inc. Method, surgical kit and device for treating glaucoma
JOP20200175A1 (ar) 2012-07-03 2017-06-16 Novartis Ag حقنة
US9757536B2 (en) 2012-07-17 2017-09-12 Novartis Ag Soft tip cannula
WO2014036009A1 (en) 2012-08-27 2014-03-06 Clearside Biomedical, Inc. Apparatus and methods for drug delivery using microneedles
CN110893188A (zh) 2012-11-08 2020-03-20 克莱尔塞德生物医学股份有限公司 用于在人类受试者中治疗眼部疾病的方法和装置
CN105246529B (zh) 2013-05-03 2019-06-14 科尼尔赛德生物医学公司 用于眼部注射的设备和方法
US10188550B2 (en) 2013-06-03 2019-01-29 Clearside Biomedical, Inc. Apparatus and methods for drug delivery using multiple reservoirs
US20150148838A1 (en) 2013-11-26 2015-05-28 Novartis Ag Systems and Methods for a Surgical Tissue Manipulator
US9730834B2 (en) 2013-12-20 2017-08-15 Novartis Ag Variable stiffness cannula and methods for a surgical system

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