JP2017160268A5 - - Google Patents
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- JP2017160268A5 JP2017160268A5 JP2017123029A JP2017123029A JP2017160268A5 JP 2017160268 A5 JP2017160268 A5 JP 2017160268A5 JP 2017123029 A JP2017123029 A JP 2017123029A JP 2017123029 A JP2017123029 A JP 2017123029A JP 2017160268 A5 JP2017160268 A5 JP 2017160268A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical
- composition
- antiarrhythmic
- administration
- minutes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 239000000203 mixture Substances 0.000 claims 21
- 239000003416 antiarrhythmic agent Substances 0.000 claims 17
- 206010003658 Atrial Fibrillation Diseases 0.000 claims 5
- 210000003748 coronary sinus Anatomy 0.000 claims 5
- 239000000443 aerosol Substances 0.000 claims 3
- 230000000694 effects Effects 0.000 claims 3
- 206010003130 Arrhythmia supraventricular Diseases 0.000 claims 2
- 206010003662 Atrial flutter Diseases 0.000 claims 2
- 208000003734 Supraventricular Tachycardia Diseases 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 229940079593 drug Drugs 0.000 claims 2
- 239000000843 powder Substances 0.000 claims 2
- 230000033764 rhythmic process Effects 0.000 claims 2
- 239000007921 spray Substances 0.000 claims 2
- 230000007704 transition Effects 0.000 claims 2
- DJBNUMBKLMJRSA-UHFFFAOYSA-N Flecainide Chemical compound FC(F)(F)COC1=CC=C(OCC(F)(F)F)C(C(=O)NCC2NCCCC2)=C1 DJBNUMBKLMJRSA-UHFFFAOYSA-N 0.000 claims 1
- 208000006011 Stroke Diseases 0.000 claims 1
- 208000001871 Tachycardia Diseases 0.000 claims 1
- 230000003288 anthiarrhythmic effect Effects 0.000 claims 1
- 239000002246 antineoplastic agent Substances 0.000 claims 1
- 206010003119 arrhythmia Diseases 0.000 claims 1
- 230000006793 arrhythmia Effects 0.000 claims 1
- 230000002763 arrhythmic effect Effects 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 238000002565 electrocardiography Methods 0.000 claims 1
- 229960000449 flecainide Drugs 0.000 claims 1
- 230000000977 initiatory effect Effects 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
- 230000002085 persistent effect Effects 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 210000003492 pulmonary vein Anatomy 0.000 claims 1
- 239000002904 solvent Substances 0.000 claims 1
- 230000006794 tachycardia Effects 0.000 claims 1
- 210000003462 vein Anatomy 0.000 claims 1
- 206010047302 ventricular tachycardia Diseases 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21038209P | 2009-03-18 | 2009-03-18 | |
| US61/210,382 | 2009-03-18 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015149197A Division JP2015193657A (ja) | 2009-03-18 | 2015-07-29 | 経肺投与によって心疾患を治療するための単位用量、エアロゾル、キット、および方法 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018204914A Division JP6715305B2 (ja) | 2009-03-18 | 2018-10-31 | 経肺投与によって心疾患を治療するための単位用量、エアロゾル、キット、および方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017160268A JP2017160268A (ja) | 2017-09-14 |
| JP2017160268A5 true JP2017160268A5 (https=) | 2017-10-26 |
Family
ID=42739985
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012500945A Withdrawn JP2012520890A (ja) | 2009-03-18 | 2010-03-18 | 経肺投与によって心疾患を治療するための単位用量、エアロゾル、キット、および方法 |
| JP2015149197A Withdrawn JP2015193657A (ja) | 2009-03-18 | 2015-07-29 | 経肺投与によって心疾患を治療するための単位用量、エアロゾル、キット、および方法 |
| JP2017123029A Pending JP2017160268A (ja) | 2009-03-18 | 2017-06-23 | 経肺投与によって心疾患を治療するための単位用量、エアロゾル、キット、および方法 |
| JP2018204914A Active JP6715305B2 (ja) | 2009-03-18 | 2018-10-31 | 経肺投与によって心疾患を治療するための単位用量、エアロゾル、キット、および方法 |
| JP2019162836A Active JP7071949B2 (ja) | 2009-03-18 | 2019-09-06 | 経肺投与によって心疾患を治療するための単位用量、エアロゾル、キット、および方法 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012500945A Withdrawn JP2012520890A (ja) | 2009-03-18 | 2010-03-18 | 経肺投与によって心疾患を治療するための単位用量、エアロゾル、キット、および方法 |
| JP2015149197A Withdrawn JP2015193657A (ja) | 2009-03-18 | 2015-07-29 | 経肺投与によって心疾患を治療するための単位用量、エアロゾル、キット、および方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018204914A Active JP6715305B2 (ja) | 2009-03-18 | 2018-10-31 | 経肺投与によって心疾患を治療するための単位用量、エアロゾル、キット、および方法 |
| JP2019162836A Active JP7071949B2 (ja) | 2009-03-18 | 2019-09-06 | 経肺投与によって心疾患を治療するための単位用量、エアロゾル、キット、および方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (5) | US8974828B2 (https=) |
| EP (3) | EP3552603B1 (https=) |
| JP (5) | JP2012520890A (https=) |
| AU (1) | AU2010226613B2 (https=) |
| CA (2) | CA2835771C (https=) |
| DK (1) | DK2413902T3 (https=) |
| ES (3) | ES3003038T3 (https=) |
| PL (1) | PL2413902T3 (https=) |
| WO (1) | WO2010107964A1 (https=) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2835771C (en) | 2009-03-18 | 2017-01-24 | Incarda Therapeutics, Inc. | Unit doses, aerosols, kits, and methods for treating heart conditions by pulmonary administration |
| IL298116A (en) | 2010-12-22 | 2023-01-01 | Syqe Medical Ltd | Method and system for drug delivery |
| US9713687B2 (en) | 2012-08-21 | 2017-07-25 | Philip Morris Usa Inc. | Ventilator aerosol delivery system with transition adapter for introducing carrier gas |
| US11191755B2 (en) | 2014-01-17 | 2021-12-07 | Cornell University | Compositions and methods for providing cardioprotective effects |
| TWI590837B (zh) * | 2014-03-25 | 2017-07-11 | 林信湧 | 一種用於治療心臟病之吸入式醫藥組成物及其備製方法 |
| EP3160565B1 (en) * | 2014-06-30 | 2021-08-18 | Syqe Medical Ltd. | Devices and systems for pulmonary delivery of active agents |
| US11298477B2 (en) | 2014-06-30 | 2022-04-12 | Syqe Medical Ltd. | Methods, devices and systems for pulmonary delivery of active agents |
| KR102482733B1 (ko) | 2014-06-30 | 2022-12-29 | 사이키 메디컬 엘티디. | 유동 조절 흡입기 디바이스 |
| PL3160552T3 (pl) | 2014-06-30 | 2020-03-31 | Syqe Medical Ltd. | Wkład z dawką leku dla urządzenia inhalacyjnego |
| US10668015B2 (en) | 2015-01-20 | 2020-06-02 | Incarda Therapeutics, Inc. | Unit aerosol doses for anticoagulation |
| EP4428119A3 (en) * | 2015-04-14 | 2024-11-13 | Milestone Pharmaceuticals Inc. | Highly water-soluble salts of a short acting phenylalkylamine calcium channel blocker and uses thereof |
| EP3851102B1 (en) | 2016-01-06 | 2025-04-16 | Syqe Medical Ltd. | Low dose therapeutic treatment |
| CN114847965A (zh) | 2016-02-01 | 2022-08-05 | 英凯达治疗公司 | 电子监测联合吸入药理学疗法管理心律失常 |
| CA3060702A1 (en) * | 2017-05-10 | 2018-11-15 | Incarda Therapeutics, Inc. | Unit doses, aerosols, kits, and methods for treating heart conditions by pulmonary administration |
| ES3040411T3 (en) * | 2018-03-22 | 2025-10-30 | Incarda Therapeutics Inc | A novel method to slow ventricular rate |
| WO2019236694A1 (en) * | 2018-06-05 | 2019-12-12 | Incarda Therapeutics, Inc. | Methods for diagnosing brugada syndrome using an aerosol |
| WO2019241597A1 (en) * | 2018-06-14 | 2019-12-19 | Cornell University | Compositions and methods for providing cardioprotective effects |
| US10512620B1 (en) | 2018-08-14 | 2019-12-24 | AltaThera Pharmaceuticals, LLC | Method of initiating and escalating sotalol hydrochloride dosing |
| US12396970B2 (en) | 2021-08-20 | 2025-08-26 | AltaThera Pharmaceuticals LLC | Anti-arrhythmic compositions and methods |
| US11344518B2 (en) | 2018-08-14 | 2022-05-31 | AltaThera Pharmaceuticals LLC | Method of converting atrial fibrillation to normal sinus rhythm and loading oral sotalol in a shortened time frame |
| US11610660B1 (en) | 2021-08-20 | 2023-03-21 | AltaThera Pharmaceuticals LLC | Antiarrhythmic drug dosing methods, medical devices, and systems |
| US11696902B2 (en) | 2018-08-14 | 2023-07-11 | AltaThera Pharmaceuticals, LLC | Method of initiating and escalating sotalol hydrochloride dosing |
| US11007185B2 (en) | 2019-08-01 | 2021-05-18 | Incarda Therapeutics, Inc. | Antiarrhythmic formulation |
| KR102891439B1 (ko) * | 2019-08-01 | 2025-11-25 | 인카다 테라퓨틱스, 인크. | 항부정맥 제제 |
| CN116867483A (zh) * | 2020-12-17 | 2023-10-10 | 英凯达治疗公司 | 用于诱导患有房性心律失常的对象的心脏复律的试剂盒和方法 |
| AU2021400335A1 (en) * | 2020-12-17 | 2023-06-22 | Incarda Therapeutics, Inc. | Kits and methods for induction of cardioversion in subjects with atrial arrhythmias |
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-
2010
- 2010-03-18 CA CA2835771A patent/CA2835771C/en active Active
- 2010-03-18 EP EP19176305.1A patent/EP3552603B1/en active Active
- 2010-03-18 WO PCT/US2010/027740 patent/WO2010107964A1/en not_active Ceased
- 2010-03-18 CA CA2755809A patent/CA2755809C/en active Active
- 2010-03-18 EP EP10754091.6A patent/EP2413902B1/en active Active
- 2010-03-18 DK DK10754091.6T patent/DK2413902T3/da active
- 2010-03-18 AU AU2010226613A patent/AU2010226613B2/en active Active
- 2010-03-18 US US13/257,249 patent/US8974828B2/en active Active
- 2010-03-18 ES ES19176305T patent/ES3003038T3/es active Active
- 2010-03-18 JP JP2012500945A patent/JP2012520890A/ja not_active Withdrawn
- 2010-03-18 ES ES10754091T patent/ES2750359T3/es active Active
- 2010-03-18 PL PL10754091T patent/PL2413902T3/pl unknown
- 2010-03-18 ES ES19176272T patent/ES3036464T3/es active Active
- 2010-03-18 EP EP19176272.3A patent/EP3552602B1/en active Active
-
2015
- 2015-02-26 US US14/632,252 patent/US10045939B2/en active Active
- 2015-07-29 JP JP2015149197A patent/JP2015193657A/ja not_active Withdrawn
-
2017
- 2017-06-23 JP JP2017123029A patent/JP2017160268A/ja active Pending
-
2018
- 2018-06-20 US US16/013,165 patent/US20180296480A1/en not_active Abandoned
- 2018-06-20 US US16/013,178 patent/US20180318213A1/en not_active Abandoned
- 2018-10-26 US US16/172,456 patent/US20190060230A1/en not_active Abandoned
- 2018-10-31 JP JP2018204914A patent/JP6715305B2/ja active Active
-
2019
- 2019-09-06 JP JP2019162836A patent/JP7071949B2/ja active Active
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