JP2017153484A5 - - Google Patents
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- Publication number
- JP2017153484A5 JP2017153484A5 JP2017096499A JP2017096499A JP2017153484A5 JP 2017153484 A5 JP2017153484 A5 JP 2017153484A5 JP 2017096499 A JP2017096499 A JP 2017096499A JP 2017096499 A JP2017096499 A JP 2017096499A JP 2017153484 A5 JP2017153484 A5 JP 2017153484A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- acid sequences
- capsid proteins
- consensus sequence
- circulating strains
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 125000003275 alpha amino acid group Chemical group 0.000 claims 5
- 108090000565 Capsid Proteins Proteins 0.000 claims 4
- 102100023321 Ceruloplasmin Human genes 0.000 claims 4
- 108091035707 Consensus sequence Proteins 0.000 claims 4
- 150000001413 amino acids Chemical class 0.000 claims 2
- 239000002131 composite material Substances 0.000 claims 2
- 239000002245 particle Substances 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 244000309711 non-enveloped viruses Species 0.000 claims 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8750408P | 2008-08-08 | 2008-08-08 | |
| US61/087,504 | 2008-08-08 | ||
| US21860309P | 2009-06-19 | 2009-06-19 | |
| US61/218,603 | 2009-06-19 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015075955A Division JP6448445B2 (ja) | 2008-08-08 | 2015-04-02 | 交差反応性の増強のための複合カプシドアミノ酸配列を含むウイルス様粒子 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017153484A JP2017153484A (ja) | 2017-09-07 |
| JP2017153484A5 true JP2017153484A5 (enExample) | 2018-02-22 |
Family
ID=41664003
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011522301A Active JP5852883B2 (ja) | 2008-08-08 | 2009-08-10 | 交差反応性の増強のための複合カプシドアミノ酸配列を含むウイルス様粒子 |
| JP2015075955A Active JP6448445B2 (ja) | 2008-08-08 | 2015-04-02 | 交差反応性の増強のための複合カプシドアミノ酸配列を含むウイルス様粒子 |
| JP2017096499A Pending JP2017153484A (ja) | 2008-08-08 | 2017-05-15 | 交差反応性の増強のための複合カプシドアミノ酸配列を含むウイルス様粒子 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011522301A Active JP5852883B2 (ja) | 2008-08-08 | 2009-08-10 | 交差反応性の増強のための複合カプシドアミノ酸配列を含むウイルス様粒子 |
| JP2015075955A Active JP6448445B2 (ja) | 2008-08-08 | 2015-04-02 | 交差反応性の増強のための複合カプシドアミノ酸配列を含むウイルス様粒子 |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US8841120B2 (enExample) |
| EP (2) | EP3382011A1 (enExample) |
| JP (3) | JP5852883B2 (enExample) |
| KR (2) | KR101793161B1 (enExample) |
| CN (2) | CN104911154A (enExample) |
| AU (1) | AU2009279456B2 (enExample) |
| CA (1) | CA2733589C (enExample) |
| DK (1) | DK2324113T3 (enExample) |
| ES (1) | ES2668836T3 (enExample) |
| HK (1) | HK1215051A1 (enExample) |
| NO (1) | NO2324113T3 (enExample) |
| PL (1) | PL2324113T3 (enExample) |
| SG (1) | SG2013057732A (enExample) |
| WO (1) | WO2010017542A1 (enExample) |
Families Citing this family (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2007345768B2 (en) * | 2006-07-27 | 2013-08-01 | Ligocyte Pharmaceuticals, Inc. | Chimeric influenza virus-like particles |
| EP2641613A1 (en) | 2006-09-29 | 2013-09-25 | Ligocyte Pharmaceuticals, Inc. | Liquid norovirus vaccine formulations comprising toll-like receptor (TLR) agonist as adjuvant |
| KR20150098681A (ko) | 2007-03-14 | 2015-08-28 | 다케다 백신즈 인코포레이티드 | 바이러스 유사 입자 정제 |
| US20100266636A1 (en) | 2007-09-18 | 2010-10-21 | Ligocyte Pharmaceuticals, Inc. | Method of conferring a protective immune response to norovirus |
| US10130696B2 (en) | 2007-09-18 | 2018-11-20 | Takeda Vaccines, Inc. | Method of conferring a protective immune response to norovirus |
| EP3382011A1 (en) | 2008-08-08 | 2018-10-03 | Takeda Vaccines, Inc. | Virus-like particles comprising composite capsid amino acid sequences for enhanced cross reactivity |
| US10130697B2 (en) | 2010-03-23 | 2018-11-20 | Wisconsin Alumni Research Foundation (Warf) | Vaccines comprising mutant attenuated influenza viruses |
| US20130171185A1 (en) * | 2010-07-06 | 2013-07-04 | Ethan Settembre | Norovirus derived immunogenic compositions and methods |
| MX379496B (es) | 2011-07-11 | 2025-03-11 | Takeda Vaccines Inc | Formulaciones parenterales de vacunas contra los norovirus. |
| EP2747778B1 (en) | 2011-08-26 | 2017-12-06 | Wisconsin Alumni Research Foundation | Influenza viruses with mutant pb2 gene segment as live attenuated vaccines |
| JP6567824B2 (ja) * | 2011-10-12 | 2019-08-28 | ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア | ヒトパピローマウイルスのワクチンおよびその使用方法 |
| JOP20130186B1 (ar) | 2012-06-22 | 2021-08-17 | Takeda Vaccines Montana Inc | تنقية الجزيئات الشبيهة بالفيروسات |
| HK1220905A1 (zh) | 2013-03-12 | 2017-05-19 | The Trustees Of The University Of Pennsylvania | 用於人乳头状瘤病毒的改进疫苗及其使用方法 |
| JP6479305B2 (ja) | 2013-07-12 | 2019-03-06 | 株式会社Umnファーマ | ウイルス様粒子の精製方法 |
| JP2015015931A (ja) | 2013-07-12 | 2015-01-29 | 株式会社Umnファーマ | ウイルス様粒子を含む培養物の製造方法 |
| US10524493B2 (en) * | 2013-09-16 | 2020-01-07 | The Johns Hopkins University | Compositions and methods for preventing or relieving symptoms of infections |
| EP3052631B1 (en) | 2013-10-03 | 2019-08-07 | Takeda Vaccines, Inc. | Methods of detection and removal of rhabdoviruses from cell lines |
| CN112057613A (zh) | 2013-11-29 | 2020-12-11 | 宾夕法尼亚大学理事会 | MERS-CoV疫苗 |
| US10053671B2 (en) | 2014-06-20 | 2018-08-21 | Wisconsin Alumni Research Foundation (Warf) | Mutations that confer genetic stability to additional genes in influenza viruses |
| MX2018002419A (es) * | 2015-08-28 | 2018-11-29 | Ology Bioservices Inc | Vacuna de norovirus. |
| US10494613B2 (en) * | 2015-08-28 | 2019-12-03 | Wisconsin Alumni Research Foundation (Warf) | Generation of infectious influenza viruses from virus-like particles |
| WO2017092711A1 (zh) * | 2015-12-04 | 2017-06-08 | 厦门大学 | 一种人乳头瘤病毒11型l1蛋白的突变体 |
| EP3417056A1 (en) | 2016-02-19 | 2018-12-26 | Wisconsin Alumni Research Foundation (WARF) | Improved influenza b virus replication for vaccine development |
| BR112018074853A2 (pt) | 2016-06-03 | 2019-04-02 | Quest Diagnostics Investments Llc | métodos para detectar a presença de pelo menos um genogrupo de norovírus em uma amostra de fezes e para selecionar um paciente que sofre de gastroenterite aguda, e, kit |
| WO2018170603A1 (en) * | 2017-03-23 | 2018-09-27 | Medicago Inc. | Norovirus fusion proteins and vlps comprising norovirus fusion proteins |
| EP3604540A4 (en) | 2017-03-31 | 2020-12-23 | The University of Tokyo | NOROVIRUS ANTIBODIES |
| JP6795468B2 (ja) * | 2017-07-14 | 2020-12-02 | ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア | ヒトパピローマウイルスのワクチンおよびその使用方法 |
| US11566050B2 (en) | 2017-10-18 | 2023-01-31 | The University Of North Carolina At Chapel Hill | Methods and compositions for norovirus vaccines and diagnostics |
| EP3700562A1 (en) | 2017-10-25 | 2020-09-02 | Wisconsin Alumni Research Foundation (WARF) | Recombinant influenza viruses with stabilized ha for replication in eggs |
| CN109776657B (zh) * | 2017-11-14 | 2021-11-26 | 北京康乐卫士生物技术股份有限公司 | 重组诺如病毒vlp颗粒和制备方法及其用途 |
| BR112020010799A2 (pt) * | 2017-11-30 | 2020-11-10 | Medicago Inc. | proteínas vp1 modificadas de norovírus e vlps que compreendem proteínas vp1 modificadas de norovírus |
| US11918646B2 (en) | 2017-12-11 | 2024-03-05 | Board Of Regents, The University Of Texas System | Dry adjuvanted immune stimulating compositions and use thereof for mucosal administration |
| CN110551183A (zh) * | 2018-06-04 | 2019-12-10 | 厦门大学 | 一种人乳头瘤病毒39型l1蛋白的突变体 |
| KR102075393B1 (ko) * | 2018-06-28 | 2020-02-11 | 한국과학기술원 | 중증 열성 혈소판 감소 증후군(sfts) 바이러스 감염 질환 예방 또는 치료용 백신 조성물 |
| US11759512B2 (en) | 2018-07-13 | 2023-09-19 | Medicago Inc. | Modified norovirus VP1 proteins and VLPs comprising modified norovirus VP1 proteins |
| JP7783047B2 (ja) | 2018-08-07 | 2025-12-09 | ウィスコンシン アルムニ リサーチ ファンデイション | 組換えの生物学的に封じ込められたフィロウイルスワクチン |
| WO2020041192A1 (en) | 2018-08-20 | 2020-02-27 | Takeda Vaccines, Inc. | Vlp formulations |
| US11389523B2 (en) | 2018-08-20 | 2022-07-19 | Wisconsin Alumni Research Foundation (Warf) | Vectors for eliciting immune responses to non-dominant epitopes in the hemagglutinin (HA) protein |
| AR117462A1 (es) * | 2018-12-20 | 2021-08-04 | Takeda Vaccines Inc | Vacuna contra norovirus, formulaciones y métodos |
| WO2020163804A1 (en) | 2019-02-08 | 2020-08-13 | Wisconsin Alumni Research Foundation (Warf) | Humanized cell line |
| WO2020223699A1 (en) | 2019-05-01 | 2020-11-05 | Wisconsin Alumni Research Foundation (Warf) | Improved influenza virus replication for vaccine development |
| US11807872B2 (en) | 2019-08-27 | 2023-11-07 | Wisconsin Alumni Research Foundation (Warf) | Recombinant influenza viruses with stabilized HA for replication in eggs |
| JP7075130B2 (ja) * | 2019-10-25 | 2022-05-25 | ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア | ヒトパピローマウイルスのワクチンおよびその使用方法 |
| WO2021150874A1 (en) | 2020-01-24 | 2021-07-29 | Wisconsin Alumni Research Foundation (Warf) | Recombinant influenza viruses with stabilized na |
| US12290562B2 (en) | 2020-03-25 | 2025-05-06 | Wisconsin Alumni Research Foundation (Warf) | Recombinant multivalent influenza viruses |
| CN114316033A (zh) * | 2020-09-29 | 2022-04-12 | 香港理工大学深圳研究院 | 一种特异性识别诺如病毒的单克隆抗体及制备方法与应用 |
| WO2022143282A1 (zh) * | 2020-12-30 | 2022-07-07 | 远大赛威信生命科学(南京)有限公司 | 诺如病毒病毒样颗粒、免疫组合物或试剂盒及其用途 |
| WO2022244860A1 (ja) * | 2021-05-20 | 2022-11-24 | デンカ株式会社 | 抗ノロウイルス抗体 |
| JP2024519800A (ja) | 2021-05-21 | 2024-05-21 | タケダ ワクチン,インコーポレイテッド | 固体組成物、フリーズドライ方法およびガラスバイアル |
| US20240402174A1 (en) | 2021-10-04 | 2024-12-05 | Takeda Vaccines, Inc. | Methods for determining norovirus-reactive antibodies |
| US20250205328A1 (en) * | 2022-03-25 | 2025-06-26 | Merck Sharp & Dohme Llc | Controlled release vaccine formulations |
Family Cites Families (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6572862B1 (en) | 1989-11-08 | 2003-06-03 | Baylor College Of Medicine | Methods and reagents to detect and characterize Norwalk and related viruses |
| AU1893592A (en) | 1991-03-25 | 1992-10-21 | Board Of Trustees Of The Leland Stanford Junior University | Norwalk virus human gastroenteritis agent and molecular cloning of corresponding cdnas |
| AU683211B2 (en) * | 1992-04-08 | 1997-11-06 | United States of America as represented by The Secretary Department of Health and Human Services, The | Wild-type measles virus glycoproteins: vaccine and detection method therefor |
| AU4851493A (en) | 1992-09-07 | 1994-03-29 | Baylor College Of Medicine | Methods and reagents to detect and characterize norwalk and related viruses |
| US5788970A (en) * | 1994-03-29 | 1998-08-04 | The University Of Maryland College Park | Chimeric infectious bursal disease virus CDNA clones, expression products and vaccines based thereon |
| PT757717E (pt) * | 1994-05-16 | 2006-09-29 | Merck & Co Inc | Vacinas de papilomavirus |
| US5645051A (en) * | 1995-04-21 | 1997-07-08 | Dura Pharmaceuticals, Inc. | Unit dose dry powder inhaler |
| US5861241A (en) * | 1995-08-16 | 1999-01-19 | University Of Massachusetts | Monoclonal antibodies for detecting Norwalk virus |
| GB9525083D0 (en) * | 1995-12-07 | 1996-02-07 | Danbiosyst Uk | Vaccine compositions |
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| US6491919B2 (en) * | 1997-04-01 | 2002-12-10 | Corixa Corporation | Aqueous immunologic adjuvant compostions of monophosphoryl lipid A |
| JP2002508748A (ja) * | 1997-05-01 | 2002-03-19 | カイロン コーポレイション | アジュバントとしてのウイルス様粒子の使用 |
| US20040265377A1 (en) * | 1997-10-27 | 2004-12-30 | Harry Seager | Solid dispersing vaccine composition for oral delivery |
| ES2262333T3 (es) * | 1998-08-14 | 2006-11-16 | MERCK & CO., INC. | Procedimiento para purificar particulas similares a virus de papilomavirus humano. |
| DE69930960T2 (de) | 1998-12-17 | 2007-04-19 | Merck & Co., Inc. | Synthetische virus-ähnliche partikel mit heterologen epitopen. |
| AU768992B2 (en) | 1999-06-22 | 2004-01-15 | Denka Seiken Co., Ltd. | SRSV detection kit |
| JP2002020399A (ja) | 2000-07-10 | 2002-01-23 | Osaka Prefecture | ノルウォークウイルス(nv)を認識するモノクローナル抗体 |
| WO2003068163A2 (en) * | 2002-02-14 | 2003-08-21 | Novavax, Inc. | Optimization of gene sequences of chimeric virus-like particles for expression in insect cells |
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| US7879338B2 (en) * | 2003-07-21 | 2011-02-01 | Boyce Thompson Institute For Plant Research | Vectors and methods for immunization against norovirus using transgenic plants |
| EP1670824A2 (en) * | 2003-09-24 | 2006-06-21 | Montana State University | Norovirus monoclonal antibodies and peptides |
| WO2005037223A2 (en) * | 2003-10-15 | 2005-04-28 | Brigham And Women's Hospital, Inc. | Methods and compositions for immunomodulation |
| US20050215501A1 (en) * | 2003-10-24 | 2005-09-29 | Coley Pharmaceutical Group, Inc. | Methods and products for enhancing epitope spreading |
| FR2863890B1 (fr) | 2003-12-19 | 2006-03-24 | Aventis Pasteur | Composition immunostimulante |
| US7481997B1 (en) * | 2004-02-12 | 2009-01-27 | Montana State University | Snow mountain virus genome sequence, virus-like particles and methods of use |
| US20050260225A1 (en) * | 2004-05-18 | 2005-11-24 | Goldberg Joanna B | Intranasal recombinant Salmonella vaccine encoding heterologous polysaccharide antigens |
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| JP4993301B2 (ja) | 2004-10-20 | 2012-08-08 | サノフィ パスツール バイオロジクス リミテッド ライアビリティ カンパニー | 日本脳炎ウイルスおよび西ナイルウイルスに対するワクチン |
| GB0428394D0 (en) | 2004-12-24 | 2005-02-02 | Chiron Srl | Saccharide conjugate vaccines |
| EP1846439A2 (en) * | 2005-01-31 | 2007-10-24 | The Johns Hopkins University | Use of consensus sequence as vaccine antigen to enhance recognition of virulent viral variants |
| AU2006216844B2 (en) | 2005-02-18 | 2012-11-08 | Novartis Vaccines And Diagnostics S.R.L. | Immunogens from uropathogenic escherichia coli |
| NZ561040A (en) | 2005-03-18 | 2009-04-30 | Cytos Biotechnology Ag | Cat allergen fusion proteins and use thereof |
| EP1736538A1 (en) | 2005-06-21 | 2006-12-27 | Cytos Biotechnology AG | Process for the preparative purification of virus-like-particles (VLPs) |
| JP4825958B2 (ja) * | 2005-08-10 | 2011-11-30 | 財団法人ヒューマンサイエンス振興財団 | 高リスク群ヒトパピローマウイルスの中和抗体を誘導する抗原 |
| CA2630220C (en) * | 2005-11-22 | 2020-10-13 | Doris Coit | Norovirus and sapovirus antigens |
| JP2007145775A (ja) * | 2005-11-29 | 2007-06-14 | Falco Life Science:Kk | ノロウイルスgiの高感度検出方法 |
| EP2641613A1 (en) * | 2006-09-29 | 2013-09-25 | Ligocyte Pharmaceuticals, Inc. | Liquid norovirus vaccine formulations comprising toll-like receptor (TLR) agonist as adjuvant |
| US20100266636A1 (en) * | 2007-09-18 | 2010-10-21 | Ligocyte Pharmaceuticals, Inc. | Method of conferring a protective immune response to norovirus |
| US10130696B2 (en) | 2007-09-18 | 2018-11-20 | Takeda Vaccines, Inc. | Method of conferring a protective immune response to norovirus |
| EP3382011A1 (en) | 2008-08-08 | 2018-10-03 | Takeda Vaccines, Inc. | Virus-like particles comprising composite capsid amino acid sequences for enhanced cross reactivity |
| SG182636A1 (en) * | 2010-01-21 | 2012-08-30 | Ligocyte Pharmaceuticals Inc | Targeted heterologous antigen presentation on calicivirus virus-like particles |
-
2009
- 2009-08-10 EP EP18158843.5A patent/EP3382011A1/en active Pending
- 2009-08-10 WO PCT/US2009/053249 patent/WO2010017542A1/en not_active Ceased
- 2009-08-10 SG SG2013057732A patent/SG2013057732A/en unknown
- 2009-08-10 DK DK09805653.4T patent/DK2324113T3/en active
- 2009-08-10 ES ES09805653.4T patent/ES2668836T3/es active Active
- 2009-08-10 JP JP2011522301A patent/JP5852883B2/ja active Active
- 2009-08-10 KR KR1020117005478A patent/KR101793161B1/ko active Active
- 2009-08-10 KR KR1020177030841A patent/KR102118458B1/ko active Active
- 2009-08-10 CN CN201510127943.5A patent/CN104911154A/zh active Pending
- 2009-08-10 NO NO09805653A patent/NO2324113T3/no unknown
- 2009-08-10 AU AU2009279456A patent/AU2009279456B2/en active Active
- 2009-08-10 CA CA2733589A patent/CA2733589C/en active Active
- 2009-08-10 CN CN200980139886.5A patent/CN102177233B/zh active Active
- 2009-08-10 PL PL09805653T patent/PL2324113T3/pl unknown
- 2009-08-10 EP EP09805653.4A patent/EP2324113B8/en active Active
-
2011
- 2011-02-08 US US13/023,363 patent/US8841120B2/en active Active
-
2014
- 2014-07-25 US US14/341,375 patent/US9518096B2/en active Active
-
2015
- 2015-04-02 JP JP2015075955A patent/JP6448445B2/ja active Active
-
2016
- 2016-03-16 HK HK16103047.9A patent/HK1215051A1/zh unknown
-
2017
- 2017-05-15 JP JP2017096499A patent/JP2017153484A/ja active Pending
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