JP2016540503A5 - - Google Patents
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- JP2016540503A5 JP2016540503A5 JP2016532031A JP2016532031A JP2016540503A5 JP 2016540503 A5 JP2016540503 A5 JP 2016540503A5 JP 2016532031 A JP2016532031 A JP 2016532031A JP 2016532031 A JP2016532031 A JP 2016532031A JP 2016540503 A5 JP2016540503 A5 JP 2016540503A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody polypeptide
- antibody
- seq
- emitters
- polypeptide according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1320408.6A GB2520353A (en) | 2013-11-19 | 2013-11-19 | Antibody polypeptides and uses thereof |
| GB1320408.6 | 2013-11-19 | ||
| GB1401973.1 | 2014-02-05 | ||
| GB201401973A GB201401973D0 (en) | 2014-02-05 | 2014-02-05 | Antibody polypeptides and uses thereof |
| PCT/GB2014/053420 WO2015075445A1 (en) | 2013-11-19 | 2014-11-19 | Humanised anti kallikrein-2 antibody |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019181801A Division JP7051777B2 (ja) | 2013-11-19 | 2019-10-02 | ヒト化抗カリクレイン-2抗体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016540503A JP2016540503A (ja) | 2016-12-28 |
| JP2016540503A5 true JP2016540503A5 (https=) | 2017-12-28 |
| JP6599859B2 JP6599859B2 (ja) | 2019-10-30 |
Family
ID=52114029
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016532031A Active JP6599859B2 (ja) | 2013-11-19 | 2014-11-19 | ヒト化抗カリクレイン−2抗体 |
| JP2019181801A Active JP7051777B2 (ja) | 2013-11-19 | 2019-10-02 | ヒト化抗カリクレイン-2抗体 |
| JP2022003634A Active JP7592654B2 (ja) | 2013-11-19 | 2022-01-13 | ヒト化抗カリクレイン-2抗体 |
| JP2024201463A Pending JP2025019101A (ja) | 2013-11-19 | 2024-11-19 | ヒト化抗カリクレイン-2抗体 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019181801A Active JP7051777B2 (ja) | 2013-11-19 | 2019-10-02 | ヒト化抗カリクレイン-2抗体 |
| JP2022003634A Active JP7592654B2 (ja) | 2013-11-19 | 2022-01-13 | ヒト化抗カリクレイン-2抗体 |
| JP2024201463A Pending JP2025019101A (ja) | 2013-11-19 | 2024-11-19 | ヒト化抗カリクレイン-2抗体 |
Country Status (24)
| Country | Link |
|---|---|
| US (3) | US10100125B2 (https=) |
| EP (2) | EP3553088B1 (https=) |
| JP (4) | JP6599859B2 (https=) |
| KR (3) | KR102442738B1 (https=) |
| CN (2) | CN112898431B (https=) |
| AU (3) | AU2014351611B2 (https=) |
| BR (1) | BR112016011025B1 (https=) |
| CA (1) | CA2930493A1 (https=) |
| CY (1) | CY1121900T1 (https=) |
| DK (2) | DK3071595T3 (https=) |
| ES (1) | ES2728515T3 (https=) |
| FI (1) | FI3553088T3 (https=) |
| HR (1) | HRP20191095T1 (https=) |
| HU (1) | HUE043875T2 (https=) |
| IL (5) | IL297678B2 (https=) |
| LT (1) | LT3071595T (https=) |
| MX (2) | MX383543B (https=) |
| PL (1) | PL3071595T3 (https=) |
| PT (1) | PT3071595T (https=) |
| RS (1) | RS58831B1 (https=) |
| RU (1) | RU2687163C1 (https=) |
| SI (1) | SI3071595T1 (https=) |
| SM (1) | SMT201900338T1 (https=) |
| WO (1) | WO2015075445A1 (https=) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013061083A2 (en) | 2011-10-28 | 2013-05-02 | Fredax Ab | Therapeutic agents and uses thereof |
| MY193914A (en) | 2012-03-05 | 2022-11-01 | Oy Arctic Partners Ab | Methods and apparatuses for predicting risk of prostate cancer and prostate gland volume |
| SMT201900338T1 (it) | 2013-11-19 | 2019-07-11 | Fredax Ab | Anticopri anti-callicreina-2 umanizzato |
| DK3123381T3 (da) | 2014-03-28 | 2023-11-27 | Opko Diagnostics Llc | Sammensætninger og fremgangsmåder relateret til diagnose af prostatacancer |
| US12326453B2 (en) | 2014-03-28 | 2025-06-10 | Opko Diagnostics, Llc | Compositions and methods for active surveillance of prostate cancer |
| WO2016160545A1 (en) | 2015-03-27 | 2016-10-06 | Opko Diagnostics, Llc | Prostate antigen standards and uses thereof |
| WO2017087826A1 (en) * | 2015-11-18 | 2017-05-26 | Memorial Sloan Kettering Cancer Center | Systems, methods, and compositions for imaging androgen receptor axis activity in carcinoma, and related therapeutic compositions and methods |
| EP4649966A3 (en) | 2016-12-01 | 2026-02-18 | Regeneron Pharmaceuticals, Inc. | Radiolabeled anti-pd-l1 antibodies for immuno-pet imaging |
| EA201991673A1 (ru) | 2017-02-10 | 2020-01-17 | Регенерон Фармасьютикалз, Инк. | Меченные радиоактивным изотопом антитела к lag3 для иммуно-пэт-визуализации |
| KR102317805B1 (ko) * | 2017-03-30 | 2021-10-27 | 이씨에스-프로가스트린 에스에이 | 전립선암을 검출하기 위한 조성물 및 방법 |
| SG11202000073XA (en) | 2017-07-24 | 2020-02-27 | Regeneron Pharma | Anti-cd8 antibodies and uses thereof |
| BR112021022237A2 (pt) | 2019-05-10 | 2022-03-29 | Janssen Biotech Inc | Queladores macrocíclicos e métodos de uso dos mesmos |
| AU2020322221A1 (en) | 2019-07-26 | 2022-03-24 | Janssen Biotech, Inc. | Anti-hK2 chimeric antigen receptor (CAR) |
| BR112022001368A2 (pt) | 2019-07-26 | 2022-05-24 | Janssen Biotech Inc | Proteínas que compreendem domínios de ligação ao antígeno de peptidase 2 relacionada à calicreína e seus usos |
| AU2020349462A1 (en) | 2019-09-16 | 2022-03-03 | Regeneron Pharmaceuticals, Inc. | Radiolabeled MET binding proteins for immuno-PET imaging |
| CN116249714A (zh) | 2020-05-27 | 2023-06-09 | 詹森生物科技公司 | 包含cd3抗原结合结构域的蛋白质及其用途 |
| EP4182353A1 (en) | 2020-07-17 | 2023-05-24 | Janssen Biotech, Inc. | Anti-idiotypic antibodies against anti-klk2 antibodies |
| UY39510A (es) * | 2020-11-10 | 2022-05-31 | Janssen Biotech Inc | Compuestos macrocíclicos y métodos para usarlos |
| CN112608365B (zh) * | 2020-12-22 | 2021-07-30 | 吉林省特医食品生物科技有限公司 | 一种减轻体重的发酵型小分子肽及其制备方法和应用 |
| CN114790245A (zh) * | 2021-01-25 | 2022-07-26 | 成都康弘生物科技有限公司 | 一种抗体及其用途 |
| JP2024503924A (ja) * | 2021-01-27 | 2024-01-29 | ヤンセン バイオテツク,インコーポレーテツド | カリクレイン関連ペプチダーゼ2抗原結合ドメインを含む免疫コンジュゲート及びその使用 |
| WO2022165130A1 (en) * | 2021-01-28 | 2022-08-04 | Astria Therapeutics, Inc. | Plasma kallikrein antibodies and uses thereof |
| US20230011134A1 (en) * | 2021-05-27 | 2023-01-12 | Janssen Biotech, Inc. | Compositions and methods for the treatment of prostate cancer |
| CA3240194A1 (en) | 2021-11-09 | 2023-05-19 | Edward Cleator | Macrocyclic compounds and methods of making the same |
| JP2024543046A (ja) | 2021-11-09 | 2024-11-19 | ヤンセン バイオテツク,インコーポレーテツド | 大環状化合物及びその診断上の使用 |
| EP4469095A1 (en) | 2022-01-26 | 2024-12-04 | Janssen Biotech, Inc. | Immunoconjugates comprising kallikrein related peptidase 2 antigen binding domains and their uses |
| WO2025244971A1 (en) | 2024-05-20 | 2025-11-27 | Janssen Biotech, Inc. | Compositions and methods for the treatment of prostate cancer |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4235871A (en) | 1978-02-24 | 1980-11-25 | Papahadjopoulos Demetrios P | Method of encapsulating biologically active materials in lipid vesicles |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| SE459005B (sv) | 1985-07-12 | 1989-05-29 | Aake Rikard Lindahl | Saett att framstaella sfaeriska polymerpartiklar |
| US5807978A (en) | 1995-06-07 | 1998-09-15 | Kokolus; William J. | Immunogenic peptides of prostate specific antigen |
| US6379669B1 (en) | 1995-08-04 | 2002-04-30 | Akhouri A. Sinha | Targeting of organs by immunoconjugates |
| CA2192782C (en) | 1995-12-15 | 2008-10-14 | Nobuyuki Takechi | Production of microspheres |
| CN1238013A (zh) | 1996-11-14 | 1999-12-08 | 梅奥医学教育及研究基金会 | 转移性前列腺癌的检测方法 |
| US7053042B1 (en) | 1999-07-29 | 2006-05-30 | Samuel Denmeade | Activation of peptide prodrugs by hK2 |
| WO2001012218A1 (en) | 1999-08-16 | 2001-02-22 | Zonagen, Inc. | Methods and materials for the treatment of prostatic carcinoma |
| FI20002127A0 (fi) | 2000-09-27 | 2000-09-27 | Artic Partners Oy Ab | Uusi vasta-aine, immunomääritys ja menetelmä eturauhassyövän havaitsemiseksi |
| WO2002098897A2 (en) | 2001-06-01 | 2002-12-12 | Cornell Research Foundation, Inc. | Modified antibodies to prostate-specific membrane antigen and uses thereof |
| US7514078B2 (en) * | 2001-06-01 | 2009-04-07 | Cornell Research Foundation, Inc. | Methods of treating prostate cancer with anti-prostate specific membrane antigen antibodies |
| US20040219163A1 (en) * | 2001-10-03 | 2004-11-04 | Frelinger John G. | Human glandular kallikrein (hk2)-specific monoclonal antibodies that enhance or inhibit the enzymatic activity of hk2 |
| AU2003210060B2 (en) | 2002-03-22 | 2010-02-25 | Aprogen, Inc. | Humanized antibody and process for preparing same |
| EP2347767A3 (en) | 2003-01-31 | 2013-06-12 | Albor Biologics, Inc. | Immune regulation based on the targeting of early activation molecules |
| WO2005094882A1 (en) * | 2004-03-03 | 2005-10-13 | Millennium Pharmaceuticals, Inc. | Modified antibodies to prostate-specific membrane antigen and uses thereof |
| CN101094869A (zh) * | 2004-08-03 | 2007-12-26 | 戴埃克斯有限公司 | Hk1结合蛋白 |
| US7462697B2 (en) | 2004-11-08 | 2008-12-09 | Epitomics, Inc. | Methods for antibody engineering |
| US8663600B2 (en) * | 2005-02-17 | 2014-03-04 | Diaprost Ab | Diagnosis of prostate cancer |
| CN101160324B (zh) * | 2005-02-18 | 2013-04-24 | 米德列斯公司 | 缺乏岩藻糖残基的抗前列腺特异性膜抗原(psma)单克隆抗体 |
| CL2007002225A1 (es) | 2006-08-03 | 2008-04-18 | Astrazeneca Ab | Agente de union especifico para un receptor del factor de crecimiento derivado de plaquetas (pdgfr-alfa); molecula de acido nucleico que lo codifica; vector y celula huesped que la comprenden; conjugado que comprende al agente; y uso del agente de un |
| US8481683B2 (en) | 2006-12-01 | 2013-07-09 | Medarex, Inc. | Human antibodies that bind CD22 and uses thereof |
| ES2560868T3 (es) * | 2006-12-22 | 2016-02-23 | Phadia Ab | Alérgeno de calicreína de próstata novedoso |
| JP2012505654A (ja) * | 2008-10-14 | 2012-03-08 | ヤンセン バイオテツク,インコーポレーテツド | 抗体をヒト化及び親和性成熟する方法 |
| WO2013061083A2 (en) * | 2011-10-28 | 2013-05-02 | Fredax Ab | Therapeutic agents and uses thereof |
| SMT201900338T1 (it) | 2013-11-19 | 2019-07-11 | Fredax Ab | Anticopri anti-callicreina-2 umanizzato |
| WO2023278463A1 (en) | 2021-06-29 | 2023-01-05 | Volastra Therapeutics, Inc. | Anti-enpp1 antibodies and uses thereof |
-
2014
- 2014-11-19 SM SM20190338T patent/SMT201900338T1/it unknown
- 2014-11-19 KR KR1020167016169A patent/KR102442738B1/ko active Active
- 2014-11-19 FI FIEP19161698.6T patent/FI3553088T3/fi active
- 2014-11-19 WO PCT/GB2014/053420 patent/WO2015075445A1/en not_active Ceased
- 2014-11-19 AU AU2014351611A patent/AU2014351611B2/en active Active
- 2014-11-19 ES ES14814696T patent/ES2728515T3/es active Active
- 2014-11-19 KR KR1020237029468A patent/KR102894975B1/ko active Active
- 2014-11-19 CN CN202011566401.5A patent/CN112898431B/zh active Active
- 2014-11-19 EP EP19161698.6A patent/EP3553088B1/en active Active
- 2014-11-19 MX MX2016006561A patent/MX383543B/es unknown
- 2014-11-19 HR HRP20191095TT patent/HRP20191095T1/hr unknown
- 2014-11-19 BR BR112016011025-0A patent/BR112016011025B1/pt active IP Right Grant
- 2014-11-19 EP EP14814696.2A patent/EP3071595B1/en active Active
- 2014-11-19 HU HUE14814696A patent/HUE043875T2/hu unknown
- 2014-11-19 RU RU2016124229A patent/RU2687163C1/ru active
- 2014-11-19 CN CN201480072422.8A patent/CN105980404B/zh active Active
- 2014-11-19 DK DK14814696.2T patent/DK3071595T3/da active
- 2014-11-19 CA CA2930493A patent/CA2930493A1/en active Pending
- 2014-11-19 US US15/036,170 patent/US10100125B2/en active Active
- 2014-11-19 PL PL14814696T patent/PL3071595T3/pl unknown
- 2014-11-19 IL IL297678A patent/IL297678B2/en unknown
- 2014-11-19 JP JP2016532031A patent/JP6599859B2/ja active Active
- 2014-11-19 SI SI201431143T patent/SI3071595T1/sl unknown
- 2014-11-19 IL IL311788A patent/IL311788B2/en unknown
- 2014-11-19 LT LTEP14814696.2T patent/LT3071595T/lt unknown
- 2014-11-19 DK DK19161698.6T patent/DK3553088T3/da active
- 2014-11-19 PT PT14814696T patent/PT3071595T/pt unknown
- 2014-11-19 KR KR1020227003223A patent/KR102574537B1/ko active Active
- 2014-11-19 RS RS20190729A patent/RS58831B1/sr unknown
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2016
- 2016-05-11 IL IL245617A patent/IL245617B/en active IP Right Grant
- 2016-05-19 MX MX2021007006A patent/MX2021007006A/es unknown
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2018
- 2018-08-30 US US16/117,522 patent/US11230609B2/en active Active
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2019
- 2019-06-20 CY CY20191100645T patent/CY1121900T1/el unknown
- 2019-10-02 JP JP2019181801A patent/JP7051777B2/ja active Active
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2020
- 2020-07-20 AU AU2020207775A patent/AU2020207775B2/en active Active
- 2020-11-04 IL IL278493A patent/IL278493B2/en unknown
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2021
- 2021-09-16 US US17/476,683 patent/US12404343B2/en active Active
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2022
- 2022-01-13 JP JP2022003634A patent/JP7592654B2/ja active Active
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2023
- 2023-08-30 AU AU2023222879A patent/AU2023222879A1/en active Pending
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2024
- 2024-11-19 JP JP2024201463A patent/JP2025019101A/ja active Pending
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2025
- 2025-09-28 IL IL323633A patent/IL323633A/en unknown
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