JP2016537029A - 三次元ｄｎａ構造におけるヌクレオチド配列の相互作用を分析する方法 - Google Patents

三次元ｄｎａ構造におけるヌクレオチド配列の相互作用を分析する方法 Download PDF

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JP2016537029A
JP2016537029A JP2016553748A JP2016553748A JP2016537029A JP 2016537029 A JP2016537029 A JP 2016537029A JP 2016553748 A JP2016553748 A JP 2016553748A JP 2016553748 A JP2016553748 A JP 2016553748A JP 2016537029 A JP2016537029 A JP 2016537029A
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dna
interaction
restriction enzyme
nucleotide sequence
restriction
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JP2016537029A5 (enExample
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グロスヴェルド，フランク
クノッホ，トビアス
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エラスムス ユニベルジテート メディッシュ セントルム ロッテルダム
エラスムス ユニベルジテート メディッシュ セントルム ロッテルダム
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/682—Signal amplification
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    • C12Q2521/00—Reaction characterised by the enzymatic activity
    • C12Q2521/30—Phosphoric diester hydrolysing, i.e. nuclease
    • C12Q2521/301—Endonuclease
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    • C12Q2521/00—Reaction characterised by the enzymatic activity
    • C12Q2521/50—Other enzymatic activities
    • C12Q2521/501—Ligase
    • C—CHEMISTRY; METALLURGY
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    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2523/00—Reactions characterised by treatment of reaction samples
    • C12Q2523/10—Characterised by chemical treatment
    • C12Q2523/101—Crosslinking agents, e.g. psoralen
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    • C12Q2565/00—Nucleic acid analysis characterised by mode or means of detection
    • C12Q2565/10—Detection mode being characterised by the assay principle
    • C12Q2565/133—Detection mode being characterised by the assay principle conformational analysis
    • C—CHEMISTRY; METALLURGY
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    • C12Q2565/00—Nucleic acid analysis characterised by mode or means of detection
    • C12Q2565/50—Detection characterised by immobilisation to a surface
    • C12Q2565/501—Detection characterised by immobilisation to a surface being an array of oligonucleotides

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  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
JP2016553748A 2013-11-18 2014-11-18 三次元ｄｎａ構造におけるヌクレオチド配列の相互作用を分析する方法 Pending JP2016537029A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1320351.8 2013-11-18
GBGB1320351.8A GB201320351D0 (en) 2013-11-18 2013-11-18 Method
PCT/IB2014/002485 WO2015071748A1 (en) 2013-11-18 2014-11-18 Method for analysing the interaction of nucleotide sequences in a three-dimensional dna structure

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JP2016537029A true JP2016537029A (ja) 2016-12-01
JP2016537029A5 JP2016537029A5 (enExample) 2017-10-19

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US (1) US10934575B2 (enExample)
EP (1) EP3071710B1 (enExample)
JP (1) JP2016537029A (enExample)
KR (1) KR102332522B1 (enExample)
CN (1) CN105992825A (enExample)
AU (1) AU2014349817B2 (enExample)
CA (1) CA2928012C (enExample)
GB (1) GB201320351D0 (enExample)
WO (1) WO2015071748A1 (enExample)

Cited By (2)

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JP2020525046A (ja) * 2017-06-26 2020-08-27 フェーズ ジェノミクス インコーポレイテッド Ｄｎａ配列のクラスター化のための方法
JP2021534807A (ja) * 2018-09-05 2021-12-16 マックス−デルブリュック−ツェントルム フューア モレキュラーレ メディツィン イン デア ヘルムホルツ−ゲマインシャフト 合成シス調節ｄｎａを操作する方法

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GB2554572B (en) * 2015-03-26 2021-06-23 Dovetail Genomics Llc Physical linkage preservation in DNA storage
JP2018518203A (ja) * 2015-06-24 2018-07-12 オックスフォード バイオダイナミックス リミテッド エピジェネティックな染色体相互作用
WO2017066908A1 (zh) * 2015-10-19 2017-04-27 安诺优达基因科技(北京)有限公司 构建高分辨率、大信息量单细胞Hi-C文库的方法
CN115369161A (zh) * 2015-12-04 2022-11-22 10X 基因组学有限公司 用于核酸分析的方法和组合物
GB201608000D0 (en) * 2016-05-06 2016-06-22 Oxford Biodynamics Ltd Chromosome detection
EP3455356B1 (en) 2016-05-13 2021-08-04 Dovetail Genomics LLC Recovering long-range linkage information from preserved samples
CA3045070A1 (en) * 2016-12-01 2018-06-07 Oxford Biodynamics Limited Application of epigenetic chromsomal interactions in cancer diagnostics
CN108300767B (zh) * 2017-10-27 2021-08-20 清华大学 一种核酸复合体中核酸区段相互作用的分析方法
CN108197431B (zh) * 2018-01-24 2022-04-05 清华大学 染色质相互作用差异的分析方法和系统
US12378592B2 (en) * 2018-01-31 2025-08-05 Dovetail Genomics, Llc. Sample prep for DNA linkage recovery
WO2020234608A1 (en) * 2019-05-22 2020-11-26 Oxford Nanopore Technologies Limited Protocol for detecting interactions within one or more dna molecules within a cell
GB2607514B (en) 2020-07-20 2023-06-21 Enanta Pharm Inc Functionalized peptides as antiviral agents
US11384090B2 (en) 2020-11-23 2022-07-12 Enanta Pharmaceuticals, Inc. Spiropyrrolidine derived antiviral agents
CN116829571A (zh) 2020-11-23 2023-09-29 英安塔制药有限公司 新型螺旋吡咯烷衍生的抗病毒药物
US11352363B1 (en) 2020-11-23 2022-06-07 Enanta Pharmaceuticals, Inc. Spiropyrrolidine derived antiviral agents
CN113215141A (zh) * 2021-02-23 2021-08-06 华南农业大学 细菌hi-c基因组及质粒构象捕获方法
US11319325B1 (en) 2021-05-11 2022-05-03 Enanta Pharmaceuticals, Inc. Macrocyclic spiropyrrolidine derived antiviral agents
US11325916B1 (en) 2021-07-29 2022-05-10 Enanta Pharmaceuticals, Inc. Spiropyrrolidine derived antiviral agents
US11339170B1 (en) 2021-07-23 2022-05-24 Enanta Pharmaceuticals, Inc. Spiropyrrolidine derived antiviral agents
GB202111195D0 (en) * 2021-08-03 2021-09-15 Cergentis B V Method for targeted sequencing
CN113946730B (zh) * 2021-10-19 2023-03-17 四川大学 一种基于基因数据的染色质层次结构分析的可视化方法
US20240095226A1 (en) * 2022-09-15 2024-03-21 Rodney Kuhn Haffnerson King Methods and related devices for storing and accessing data using multi-level fractal grids

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JP2009500031A (ja) * 2005-07-04 2009-01-08 エラスムス ユニバーシティ メディカル センター 染色体コンフォメーションキャプチャ−オン−チップ（４ｃ）アッセイ
JP2010515449A (ja) * 2007-01-11 2010-05-13 エラスムス ユニバーシティ メディカル センター 環状染色体コンホメーション捕捉（４ｃ）
JP2013530709A (ja) * 2010-07-09 2013-08-01 セルゲンティス ビー．ブイ． 対象の３−ｄゲノム領域配列決定戦略
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JP2010515449A (ja) * 2007-01-11 2010-05-13 エラスムス ユニバーシティ メディカル センター 環状染色体コンホメーション捕捉（４ｃ）
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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020525046A (ja) * 2017-06-26 2020-08-27 フェーズ ジェノミクス インコーポレイテッド Ｄｎａ配列のクラスター化のための方法
JP7277058B2 (ja) 2017-06-26 2023-05-18 フェーズ ジェノミクス インコーポレイテッド Ｄｎａ配列のクラスター化のための方法
US11753637B2 (en) 2017-06-26 2023-09-12 Phase Genomics Inc. Method for the clustering of DNA sequences
JP2021534807A (ja) * 2018-09-05 2021-12-16 マックス−デルブリュック−ツェントルム フューア モレキュラーレ メディツィン イン デア ヘルムホルツ−ゲマインシャフト 合成シス調節ｄｎａを操作する方法
JP2024156849A (ja) * 2018-09-05 2024-11-06 マックス－デルブリュック－ツェントルム フューア モレキュラーレ メディツィン イン デア ヘルムホルツ－ゲマインシャフト 合成シス調節ｄｎａを操作する方法

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EP3071710A1 (en) 2016-09-28
AU2014349817B2 (en) 2020-11-12
WO2015071748A1 (en) 2015-05-21
CA2928012A1 (en) 2015-05-21
KR102332522B1 (ko) 2021-11-29
GB201320351D0 (en) 2014-01-01
CN105992825A (zh) 2016-10-05
US10934575B2 (en) 2021-03-02
CA2928012C (en) 2023-05-16
AU2014349817A1 (en) 2016-05-19
US20160289738A1 (en) 2016-10-06
KR20160079120A (ko) 2016-07-05
EP3071710B1 (en) 2019-05-15

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