JP2016536983A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2016536983A5 JP2016536983A5 JP2016525617A JP2016525617A JP2016536983A5 JP 2016536983 A5 JP2016536983 A5 JP 2016536983A5 JP 2016525617 A JP2016525617 A JP 2016525617A JP 2016525617 A JP2016525617 A JP 2016525617A JP 2016536983 A5 JP2016536983 A5 JP 2016536983A5
- Authority
- JP
- Japan
- Prior art keywords
- region
- microfluidic
- channel
- con
- enclosure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims 19
- 238000002955 isolation Methods 0.000 claims 11
- 230000014759 maintenance of location Effects 0.000 claims 8
- 238000004720 dielectrophoresis Methods 0.000 claims 7
- 239000003795 chemical substances by application Substances 0.000 claims 6
- 239000000758 substrate Substances 0.000 claims 6
- 230000004913 activation Effects 0.000 claims 5
- 239000000463 material Substances 0.000 claims 5
- 230000003213 activating effect Effects 0.000 claims 4
- 239000012491 analyte Substances 0.000 claims 4
- 239000012530 fluid Substances 0.000 claims 4
- 238000002372 labelling Methods 0.000 claims 3
- 239000004065 semiconductor Substances 0.000 claims 3
- 239000000427 antigen Substances 0.000 claims 2
- 102000036639 antigens Human genes 0.000 claims 2
- 108091007433 antigens Proteins 0.000 claims 2
- 238000009792 diffusion process Methods 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 230000035515 penetration Effects 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 102000004169 proteins and genes Human genes 0.000 claims 2
- 238000000926 separation method Methods 0.000 claims 2
- 101710120037 Toxin CcdB Proteins 0.000 claims 1
- 230000004888 barrier function Effects 0.000 claims 1
- 150000001720 carbohydrates Chemical class 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 239000007850 fluorescent dye Substances 0.000 claims 1
- 239000002207 metabolite Substances 0.000 claims 1
- 238000012544 monitoring process Methods 0.000 claims 1
- 102000039446 nucleic acids Human genes 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
- 150000007523 nucleic acids Chemical class 0.000 claims 1
- 238000005406 washing Methods 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2019129854A JP6944490B2 (ja) | 2013-10-22 | 2019-07-12 | 隔離囲いを有するマイクロ流体デバイスおよびそれによる生物学的微小物体の試験方法 |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361996969P | 2013-10-22 | 2013-10-22 | |
| US61/996,969 | 2013-10-22 | ||
| US201462058658P | 2014-10-01 | 2014-10-01 | |
| US62/058,658 | 2014-10-01 | ||
| US14/520,568 US10010882B2 (en) | 2013-10-22 | 2014-10-22 | Microfluidic devices having isolation pens and methods of testing biological micro-objects with same |
| US14/520,568 | 2014-10-22 | ||
| PCT/US2014/061837 WO2015061497A1 (en) | 2013-10-22 | 2014-10-22 | Microfluidic devices having isolation pens and methods of testing biological micro-objects with same |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019129854A Division JP6944490B2 (ja) | 2013-10-22 | 2019-07-12 | 隔離囲いを有するマイクロ流体デバイスおよびそれによる生物学的微小物体の試験方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016536983A JP2016536983A (ja) | 2016-12-01 |
| JP2016536983A5 true JP2016536983A5 (cg-RX-API-DMAC7.html) | 2017-11-30 |
| JP6557658B2 JP6557658B2 (ja) | 2019-08-07 |
Family
ID=52993522
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016525617A Active JP6557658B2 (ja) | 2013-10-22 | 2014-10-22 | 隔離囲いを有するマイクロ流体デバイスおよびそれによる生物学的微小物体の試験方法 |
| JP2019129854A Active JP6944490B2 (ja) | 2013-10-22 | 2019-07-12 | 隔離囲いを有するマイクロ流体デバイスおよびそれによる生物学的微小物体の試験方法 |
| JP2021147377A Active JP7333365B2 (ja) | 2013-10-22 | 2021-09-10 | 隔離囲いを有するマイクロ流体デバイスおよびそれによる生物学的微小物体の試験方法 |
| JP2023091448A Pending JP2023115034A (ja) | 2013-10-22 | 2023-06-02 | 隔離囲いを有するマイクロ流体デバイスおよびそれによる生物学的微小物体の試験方法 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019129854A Active JP6944490B2 (ja) | 2013-10-22 | 2019-07-12 | 隔離囲いを有するマイクロ流体デバイスおよびそれによる生物学的微小物体の試験方法 |
| JP2021147377A Active JP7333365B2 (ja) | 2013-10-22 | 2021-09-10 | 隔離囲いを有するマイクロ流体デバイスおよびそれによる生物学的微小物体の試験方法 |
| JP2023091448A Pending JP2023115034A (ja) | 2013-10-22 | 2023-06-02 | 隔離囲いを有するマイクロ流体デバイスおよびそれによる生物学的微小物体の試験方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (4) | US10010882B2 (cg-RX-API-DMAC7.html) |
| EP (3) | EP3473700B1 (cg-RX-API-DMAC7.html) |
| JP (4) | JP6557658B2 (cg-RX-API-DMAC7.html) |
| KR (4) | KR102113377B1 (cg-RX-API-DMAC7.html) |
| AU (3) | AU2014340089B2 (cg-RX-API-DMAC7.html) |
| CA (2) | CA2927701C (cg-RX-API-DMAC7.html) |
| IL (3) | IL283153B2 (cg-RX-API-DMAC7.html) |
| SG (2) | SG10202006525PA (cg-RX-API-DMAC7.html) |
| WO (1) | WO2015061497A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (67)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8535241B2 (en) | 2011-10-13 | 2013-09-17 | Magnolia Medical Technologies, Inc. | Fluid diversion mechanism for bodily-fluid sampling |
| EP2856177B1 (en) | 2012-05-25 | 2020-11-18 | The University of North Carolina At Chapel Hill | Microfluidic devices, solid supports for reagents and related methods |
| WO2014022275A1 (en) | 2012-08-01 | 2014-02-06 | Magnolia Medical Technologies, Inc. | Fluid diversion mechanism for bodily-fluid sampling |
| IL321622A (en) | 2012-12-04 | 2025-08-01 | Magnolia Medical Technologies Inc | Sterile bodily-fluid collection device and methods |
| AU2014340089B2 (en) | 2013-10-22 | 2019-09-26 | Berkeley Lights, Inc. | Microfluidic devices having isolation pens and methods of testing biological micro-objects with same |
| US9889445B2 (en) | 2013-10-22 | 2018-02-13 | Berkeley Lights, Inc. | Micro-fluidic devices for assaying biological activity |
| GB201320146D0 (en) | 2013-11-14 | 2014-01-01 | Cambridge Entpr Ltd | Fluidic separation and detection |
| US11192107B2 (en) | 2014-04-25 | 2021-12-07 | Berkeley Lights, Inc. | DEP force control and electrowetting control in different sections of the same microfluidic apparatus |
| US20150352547A1 (en) | 2014-06-06 | 2015-12-10 | Berkeley Lights, Inc. | Isolating Microfluidic Structures and Trapping Bubbles |
| US11754563B2 (en) * | 2014-11-20 | 2023-09-12 | Global Life Sciences Solutions Operations UK Ltd | Porous membranes with a polymer grafting, methods and uses thereof |
| EP3227025B1 (en) | 2014-12-05 | 2019-03-27 | The Regents of The University of California | Single-sided light-actuated microfluidic device with integrated mesh ground |
| US10058865B2 (en) | 2014-12-08 | 2018-08-28 | Berkeley Lights, Inc. | Actuated microfluidic structures for directed flow in a microfluidic device and methods of use thereof |
| KR102369770B1 (ko) | 2014-12-08 | 2022-03-02 | 버클리 라잇츠, 인크. | 측방향/수직 트랜지스터 구조들을 포함하는 미세유체 디바이스 및 그 제조 및 사용 프로세스 |
| EP3230718B1 (en) | 2014-12-09 | 2022-03-02 | Berkeley Lights, Inc. | Automated detection of assay-positive areas or of analyte quantities in microfluidic devices |
| CN107223208B (zh) | 2014-12-09 | 2021-04-09 | 伯克利之光生命科技公司 | 微流体装置中微物体的自动检测和重新定位 |
| TWI700125B (zh) | 2014-12-10 | 2020-08-01 | 美商柏克萊燈光有限公司 | 用於操作電氣動力裝置之系統 |
| WO2016094715A2 (en) | 2014-12-10 | 2016-06-16 | Berkeley Lights, Inc. | Movement and selection of micro-objects in a microfluidic apparatus |
| HK1248750A1 (zh) * | 2015-04-22 | 2018-10-19 | 伯克利之光生命科技公司 | 用於微流体装置的培养站 |
| US10751715B1 (en) | 2015-04-22 | 2020-08-25 | Berkeley Lights, Inc. | Microfluidic reporter cell assay methods and kits thereof |
| CA3176018A1 (en) | 2015-04-22 | 2016-10-27 | Berkeley Lights, Inc. | Microfluidic device for culturing biological cells and methods of use thereof |
| WO2016172623A1 (en) | 2015-04-22 | 2016-10-27 | Berkeley Lights, Inc. | Manipulation of cell nuclei in a micro-fluidic device |
| JP2018512875A (ja) | 2015-04-22 | 2018-05-24 | バークレー ライツ,インコーポレイテッド | マイクロ流体デバイスにおける細胞の凍結及び保管 |
| GB201512600D0 (en) * | 2015-07-17 | 2015-08-26 | Koniku Ltd | Cell culture, transport and investigation |
| CN114272966B (zh) * | 2015-07-22 | 2023-11-07 | 北卡罗来纳-查佩尔山大学 | 含有具有空间分离的珠保留和信号检测段的珠孔几何结构的流体装置和相关方法 |
| US10799865B2 (en) | 2015-10-27 | 2020-10-13 | Berkeley Lights, Inc. | Microfluidic apparatus having an optimized electrowetting surface and related systems and methods |
| IL299366A (en) * | 2015-11-23 | 2023-02-01 | Berkeley Lights Inc | In situ-generated microfluidic isolation structures, kits and methods of use thereof |
| CN108603878A (zh) * | 2015-12-08 | 2018-09-28 | 伯克利之光生命科技公司 | 微流体设备和试剂盒及其使用方法 |
| IL299835A (en) | 2015-12-30 | 2023-03-01 | Berkeley Lights Inc | Microfluidic devices for optically activated convection and displacement, and their kits and methods |
| TWI808934B (zh) | 2015-12-31 | 2023-07-21 | 美商伯克利之光生命科技公司 | 經工程化以表現促發炎多肽之腫瘤浸潤細胞 |
| WO2017123697A1 (en) * | 2016-01-13 | 2017-07-20 | Duke University | Platforms for single cell analysis |
| TWI821913B (zh) * | 2016-01-15 | 2023-11-11 | 美商伯克利之光生命科技公司 | 製造患者專一性抗癌治療劑之方法及使用該治療劑之治療方法 |
| WO2017160991A1 (en) | 2016-03-16 | 2017-09-21 | Lavieu Gregory G | Methods, systems and devices for selection and generation of genome edited clones |
| AU2017234787B2 (en) * | 2016-03-17 | 2022-12-22 | Berkeley Lights, Inc. | Selection and cloning of T lymphocytes in a microfluidic device |
| CN109311930B (zh) * | 2016-03-31 | 2023-02-24 | 伯克利之光生命科技公司 | 核酸稳定试剂、试剂盒及其使用方法 |
| CN115184315A (zh) * | 2016-04-15 | 2022-10-14 | 伯克利之光生命科技公司 | 用于坞内测定的方法、系统和试剂盒 |
| US10675625B2 (en) | 2016-04-15 | 2020-06-09 | Berkeley Lights, Inc | Light sequencing and patterns for dielectrophoretic transport |
| WO2017205830A1 (en) | 2016-05-26 | 2017-11-30 | Berkeley Lights, Inc. | Covalently modified surfaces, kits, and methods of preparation and use |
| KR102456488B1 (ko) * | 2016-07-21 | 2022-10-19 | 버클리 라잇츠, 인크. | 미세유체 디바이스에서의 t 림프구들의 분류 |
| JP7280181B2 (ja) * | 2016-10-01 | 2023-05-23 | バークレー ライツ,インコーポレイテッド | Dnaバーコード組成物及びマイクロ流体デバイスによるインサイチュ同定法 |
| DK3529611T3 (da) * | 2016-10-23 | 2023-02-06 | Berkeley Lights Inc | Fremgangsmåder til screening af b-cellelymfocytter |
| CA3045333A1 (en) | 2016-12-01 | 2018-06-07 | Berkeley Lights, Inc. | Automated detection and repositioning of micro-objects in microfluidic devices |
| CN110248733B (zh) | 2016-12-01 | 2022-01-11 | 伯克利之光生命科技公司 | 用于对微物体成像的设备、系统和方法 |
| EP3551745A4 (en) | 2016-12-12 | 2020-07-15 | Xcella Biosciences, Inc. | SCREENING METHODS AND SYSTEMS USING MICROCAPILLARY NETWORKS |
| CA3048645A1 (en) * | 2016-12-30 | 2018-07-05 | The Regents Of The University Of California | Methods for selection and generation of genome edited t cells |
| US11156626B2 (en) | 2016-12-30 | 2021-10-26 | xCella Biosciences, Inc. | Multi-stage sample recovery system |
| WO2018208332A2 (en) | 2017-02-17 | 2018-11-15 | Koniku, Inc. | Systems for detection |
| WO2018226900A2 (en) | 2017-06-06 | 2018-12-13 | Zymergen Inc. | A htp genomic engineering platform for improving fungal strains |
| US20180353117A1 (en) | 2017-06-09 | 2018-12-13 | Magnolia Medical Technologies, Inc. | Fluid control devices and methods of using the same |
| TWI832820B (zh) | 2017-07-21 | 2024-02-21 | 美商伯克利之光生命科技公司 | 抗原呈現合成表面、共價功能化表面、經活化之t細胞及其用途 |
| EP3721209B1 (en) | 2017-10-15 | 2024-02-07 | Berkeley Lights, Inc. | Methods for in-pen assays |
| CN112154190A (zh) | 2018-05-18 | 2020-12-29 | 北卡罗来纳-查佩尔山大学 | 用于改善基材的表面性质的组合物、装置和方法 |
| CA3100701A1 (en) | 2018-05-31 | 2019-12-05 | Berkeley Lights, Inc. | Automated detection and characterization of micro-objects in microfluidic devices |
| KR20210018219A (ko) | 2018-06-06 | 2021-02-17 | 지머젠 인코포레이티드 | 발효 및 생산 중 곰팡이 형태를 제어하기 위한 신호 전달에 포함된 유전자의 조작 |
| EP3849705A4 (en) * | 2018-09-14 | 2022-06-01 | Berkeley Lights, Inc. | Methods for assaying binding affinity |
| EP3853352A4 (en) | 2018-09-21 | 2022-08-10 | Berkeley Lights, Inc. | FUNCTIONALIZED TRUCK PLATE, PROCESS FOR ITS MANUFACTURE AND ITS USE |
| KR20210078510A (ko) | 2018-10-11 | 2021-06-28 | 버클리 라잇츠, 인크. | 최적화된 단백질 생성의 확인을 위한 시스템 및 방법, 및 이를 위한 키트 |
| AU2019362009A1 (en) | 2018-10-18 | 2021-06-03 | Berkeley Lights, Inc. | Proto-antigen-presenting synthetic surfaces, activated t cells, and uses thereof |
| KR20210089193A (ko) * | 2018-11-01 | 2021-07-15 | 버클리 라잇츠, 인크. | 미세유체 디바이스에서 생물학적 세포를 분석하기 위한 방법 |
| EP3883692A4 (en) | 2018-11-19 | 2022-08-31 | Berkeley Lights, Inc. | MICROFLUID DEVICE WITH PROGRAMMABLE SWITCHING ELEMENTS |
| US12318775B2 (en) | 2018-12-06 | 2025-06-03 | xCella Biosciences, Inc. | Lateral loading of microcapillary arrays |
| WO2020168258A1 (en) | 2019-02-15 | 2020-08-20 | Berkeley Lights, Inc. | Laser-assisted repositioning of a micro-object and culturing of an attachment-dependent cell in a microfluidic environment |
| IT201900002777A1 (it) * | 2019-02-26 | 2020-08-26 | Menarini Silicon Biosystems Spa | Metodo e sistema microfluidico per l'isolamento di particelle |
| CN116174068A (zh) | 2019-04-30 | 2023-05-30 | 伯克利之光生命科技公司 | 用于包封和测定细胞的方法 |
| CA3157616A1 (en) | 2019-11-17 | 2021-05-20 | Darshan THAKER | Systems and methods for analyses of biological samples |
| CN115516318A (zh) | 2020-03-09 | 2022-12-23 | 伯克利之光生命科技公司 | 用于坞内测定的方法、系统和试剂盒 |
| US11479779B2 (en) | 2020-07-31 | 2022-10-25 | Zymergen Inc. | Systems and methods for high-throughput automated strain generation for non-sporulating fungi |
| AU2021338364A1 (en) | 2020-09-07 | 2023-03-30 | Berkeley Lights, Inc. | Methods of assaying a biological cell |
Family Cites Families (74)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997040385A1 (en) | 1996-04-25 | 1997-10-30 | Bioarray Solutions, Llc | Light-controlled electrokinetic assembly of particles near surfaces |
| US6294063B1 (en) | 1999-02-12 | 2001-09-25 | Board Of Regents, The University Of Texas System | Method and apparatus for programmable fluidic processing |
| EP1106244A3 (en) * | 1999-03-03 | 2001-11-21 | Symyx Technologies, Inc. | Chemical processing microsystems and controlling reaction conditions in same |
| US6942776B2 (en) | 1999-05-18 | 2005-09-13 | Silicon Biosystems S.R.L. | Method and apparatus for the manipulation of particles by means of dielectrophoresis |
| EP1194693B1 (en) | 1999-06-28 | 2006-10-25 | California Institute Of Technology | Microfabricated elastomeric valve and pump systems |
| US20030007894A1 (en) | 2001-04-27 | 2003-01-09 | Genoptix | Methods and apparatus for use of optical forces for identification, characterization and/or sorting of particles |
| ITTO20010411A1 (it) | 2001-05-02 | 2002-11-02 | Silicon Biosystems S R L | Metodo e dispositivo per l'esecuzione di test e saggi ad alta processivita' ed alto valore biologico su cellule e/o composti. |
| US20030175947A1 (en) * | 2001-11-05 | 2003-09-18 | Liu Robin Hui | Enhanced mixing in microfluidic devices |
| US7312085B2 (en) | 2002-04-01 | 2007-12-25 | Fluidigm Corporation | Microfluidic particle-analysis systems |
| EP2666849A3 (en) | 2002-04-01 | 2014-05-28 | Fluidigm Corporation | Microfluidic particle-analysis systems |
| US6958132B2 (en) | 2002-05-31 | 2005-10-25 | The Regents Of The University Of California | Systems and methods for optical actuation of microfluidics based on opto-electrowetting |
| US7790443B2 (en) | 2002-08-27 | 2010-09-07 | Vanderbilt University | Bioreactors with substance injection capacity |
| WO2004065618A2 (en) | 2003-01-16 | 2004-08-05 | Thermogenic Imaging | Methods and devices for monitoring cellular metabolism in microfluidic cell-retaining chambers |
| AU2004228678A1 (en) | 2003-04-03 | 2004-10-21 | Fluidigm Corp. | Microfluidic devices and methods of using same |
| JP4328168B2 (ja) | 2003-10-02 | 2009-09-09 | ソニー株式会社 | 毛細管現象を利用する物質間の相互作用検出部と該検出部を用いる方法及びバイオアッセイ用基板 |
| WO2005072399A2 (en) | 2004-01-29 | 2005-08-11 | Massachusetts Institute Of Technology | Microscale sorting cytometer |
| US8765454B2 (en) | 2004-02-18 | 2014-07-01 | Xiaochuan Zhou | Fluidic devices and methods for multiplex chemical and biochemical reactions |
| JP2007537729A (ja) | 2004-04-12 | 2007-12-27 | ザ・レジェンツ・オブ・ザ・ユニバーシティ・オブ・カリフォルニア | 微粒子及び細胞の操作用の光電子ピンセット |
| JPWO2005121767A1 (ja) * | 2004-05-25 | 2008-04-10 | 有限会社フルイド | マイクロ流体デバイス及びこれを用いる分析分取装置 |
| US20060091015A1 (en) | 2004-11-01 | 2006-05-04 | Applera Corporation | Surface modification for non-specific adsorption of biological material |
| EP3029135B1 (en) | 2005-07-07 | 2021-03-17 | The Regents of the University of California | Apparatus for cell culture array |
| CN101548004A (zh) | 2005-08-19 | 2009-09-30 | 加利福尼亚大学董事会 | 用于诊断学和细胞分析的微流体方法 |
| CA2616504A1 (en) | 2005-08-19 | 2007-03-01 | The Regents Of The University Of California | Microfluidic methods for diagnostics and cellular analysis |
| WO2007102839A2 (en) | 2005-10-27 | 2007-09-13 | Applera Corporation | Optoelectronic separation of biomolecules |
| US7964078B2 (en) * | 2005-11-07 | 2011-06-21 | The Regents Of The University Of California | Microfluidic device for cell and particle separation |
| US7763453B2 (en) | 2005-11-30 | 2010-07-27 | Micronics, Inc. | Microfluidic mixing and analytic apparatus |
| WO2008002462A2 (en) | 2006-06-23 | 2008-01-03 | Micronics, Inc. | Methods and devices for microfluidic point-of-care immunoassays |
| US8124015B2 (en) | 2006-02-03 | 2012-02-28 | Institute For Systems Biology | Multiplexed, microfluidic molecular assay device and assay method |
| US9040288B2 (en) | 2006-03-24 | 2015-05-26 | Handylab, Inc. | Integrated system for processing microfluidic samples, and method of using the same |
| US8980198B2 (en) | 2006-04-18 | 2015-03-17 | Advanced Liquid Logic, Inc. | Filler fluids for droplet operations |
| US9023642B2 (en) | 2006-07-07 | 2015-05-05 | The University Of Houston System | Method and apparatus for a miniature bioreactor system for long-term cell culture |
| EP2125219B1 (en) | 2007-01-19 | 2016-08-10 | Fluidigm Corporation | High precision microfluidic devices and methods |
| WO2008119066A1 (en) | 2007-03-28 | 2008-10-02 | The Regents Of The University Of California | Single-sided lateral-field and phototransistor-based optoelectronic tweezers |
| ATE554859T1 (de) | 2007-05-24 | 2012-05-15 | Univ California | Integrierte fluidische vorrichtungen mit magnetischer sortierung |
| US7736891B2 (en) | 2007-09-11 | 2010-06-15 | University Of Washington | Microfluidic assay system with dispersion monitoring |
| CA2705213C (en) | 2007-11-07 | 2016-10-04 | The University Of British Columbia | Microfluidic device and method of using same |
| JP2011516867A (ja) | 2008-04-03 | 2011-05-26 | ザ レジェンツ オブ ザ ユニヴァースティ オブ カリフォルニア | 細胞、小胞、ナノ粒子およびバイオマーカーを分離および単離するためのエキソビボの多次元システム |
| EP2279238A2 (en) * | 2008-04-21 | 2011-02-02 | Cell Kinetics, Ltd. | Flat cell carriers with cell traps |
| CN101275114A (zh) | 2008-04-22 | 2008-10-01 | 北京大学 | 一种微流细胞培养阵列及其应用 |
| KR100991752B1 (ko) | 2008-07-15 | 2010-11-03 | 한국과학기술원 | 단일 평면 광전자 소자를 이용한 미세입자 구동장치 및구동방법 |
| WO2010014078A1 (en) | 2008-07-28 | 2010-02-04 | Agere Systems Inc. | Systems and methods for variable compensated fly height measurement |
| GB2464300A (en) * | 2008-10-10 | 2010-04-14 | Univ Dublin City | Microfluidic multiplexed cellular and molecular analysis device and method |
| JP2012522518A (ja) | 2009-04-03 | 2012-09-27 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 細胞および生体粒子を選別するための方法および装置 |
| US20100273681A1 (en) | 2009-04-27 | 2010-10-28 | Wisconsin Alumni Research Foundation | Combinatorial chemistry reaction cell with optical tweezers |
| GB0909923D0 (en) | 2009-06-09 | 2009-07-22 | Oxford Gene Tech Ip Ltd | Picowell capture devices for analysing single cells or other particles |
| JP2011000079A (ja) | 2009-06-19 | 2011-01-06 | Univ Of Tokyo | 粒子を操作する方法及びマイクロ流体装置 |
| TW201109653A (en) | 2009-07-06 | 2011-03-16 | Sony Corp | Microfluidic device |
| CN102472697A (zh) | 2009-07-06 | 2012-05-23 | 索尼公司 | 微流体装置 |
| US20110143378A1 (en) | 2009-11-12 | 2011-06-16 | CyVek LLC. | Microfluidic method and apparatus for high performance biological assays |
| US20130118905A1 (en) | 2010-05-26 | 2013-05-16 | Tosoh Corporation | Biological sample immobilizing apparatus |
| CN101947124B (zh) * | 2010-06-25 | 2012-07-04 | 博奥生物有限公司 | 一种集成式微流控芯片装置及其使用方法 |
| US10087408B2 (en) | 2010-07-07 | 2018-10-02 | The University Of British Columbia | System and method for microfluidic cell culture |
| US20130115606A1 (en) | 2010-07-07 | 2013-05-09 | The University Of British Columbia | System and method for microfluidic cell culture |
| US9188593B2 (en) | 2010-07-16 | 2015-11-17 | The University Of British Columbia | Methods for assaying cellular binding interactions |
| US9533306B2 (en) | 2010-08-02 | 2017-01-03 | The Regents Of The University Of California | Single sided continuous optoelectrowetting (SCEOW) device for droplet manipulation with light patterns |
| CA2809877C (en) * | 2010-09-14 | 2021-11-23 | The Regents Of The University Of California | Method and device for isolating cells from heterogeneous solution using microfluidic trapping vortices |
| US8581167B2 (en) | 2010-11-16 | 2013-11-12 | Palo Alto Research Center Incorporated | Optically patterned virtual electrodes and interconnects on polymer and semiconductive substrates |
| WO2012072823A1 (en) * | 2010-12-03 | 2012-06-07 | Mindseeds Laboratories Srl | Rapid screening of monoclonal antibodies |
| CN103392124B (zh) | 2010-12-03 | 2016-04-20 | 塞普莱有限公司 | 细胞功能的微分析 |
| CN103732731A (zh) | 2011-05-27 | 2014-04-16 | 不列颠哥伦比亚大学 | 用于高通量分析的微流控细胞捕获和分析设备 |
| US9227200B2 (en) | 2011-06-03 | 2016-01-05 | The Regents Of The University Of California | Microfluidic devices with flexible optically transparent electrodes |
| CA2842359A1 (en) | 2011-08-01 | 2013-02-07 | Denovo Sciences | Cell capture system and method of use |
| US9050593B2 (en) * | 2011-11-23 | 2015-06-09 | Wisconsin Alumni Research Foundation | Self-loading microfluidic device and methods of use |
| US10626435B2 (en) * | 2012-03-28 | 2020-04-21 | Northeastern University | Nanofluidic device for isolating, growing, and characterizing microbial cells |
| TWI512383B (zh) | 2012-07-04 | 2015-12-11 | Ind Tech Res Inst | 光學感應式介電泳裝置 |
| US9857333B2 (en) * | 2012-10-31 | 2018-01-02 | Berkeley Lights, Inc. | Pens for biological micro-objects |
| US9403172B2 (en) | 2012-11-08 | 2016-08-02 | Berkeley Lights, Inc. | Circuit based optoelectronic tweezers |
| KR102668221B1 (ko) | 2013-03-28 | 2024-05-23 | 더 유니버시티 오브 브리티쉬 콜롬비아 | 미세유동 장치 및 분비물의 다세포 검정법에서의 그의 사용 방법 |
| KR102113990B1 (ko) | 2013-10-22 | 2020-05-25 | 버클리 라잇츠, 인크. | 생물학적 활성물 분석용 미세 유체 소자 |
| US9889445B2 (en) | 2013-10-22 | 2018-02-13 | Berkeley Lights, Inc. | Micro-fluidic devices for assaying biological activity |
| AU2014340089B2 (en) | 2013-10-22 | 2019-09-26 | Berkeley Lights, Inc. | Microfluidic devices having isolation pens and methods of testing biological micro-objects with same |
| KR102369770B1 (ko) | 2014-12-08 | 2022-03-02 | 버클리 라잇츠, 인크. | 측방향/수직 트랜지스터 구조들을 포함하는 미세유체 디바이스 및 그 제조 및 사용 프로세스 |
| WO2016094715A2 (en) | 2014-12-10 | 2016-06-16 | Berkeley Lights, Inc. | Movement and selection of micro-objects in a microfluidic apparatus |
| CA3176018A1 (en) | 2015-04-22 | 2016-10-27 | Berkeley Lights, Inc. | Microfluidic device for culturing biological cells and methods of use thereof |
-
2014
- 2014-10-22 AU AU2014340089A patent/AU2014340089B2/en active Active
- 2014-10-22 JP JP2016525617A patent/JP6557658B2/ja active Active
- 2014-10-22 KR KR1020167013301A patent/KR102113377B1/ko active Active
- 2014-10-22 CA CA2927701A patent/CA2927701C/en active Active
- 2014-10-22 IL IL283153A patent/IL283153B2/en unknown
- 2014-10-22 KR KR1020227003226A patent/KR102514162B1/ko active Active
- 2014-10-22 WO PCT/US2014/061837 patent/WO2015061497A1/en not_active Ceased
- 2014-10-22 EP EP18205544.2A patent/EP3473700B1/en active Active
- 2014-10-22 EP EP20174036.2A patent/EP3760703A1/en active Pending
- 2014-10-22 US US14/520,568 patent/US10010882B2/en active Active
- 2014-10-22 KR KR1020207013753A patent/KR102221894B1/ko active Active
- 2014-10-22 IL IL297654A patent/IL297654A/en unknown
- 2014-10-22 SG SG10202006525PA patent/SG10202006525PA/en unknown
- 2014-10-22 CA CA3095333A patent/CA3095333C/en active Active
- 2014-10-22 SG SG11201602629RA patent/SG11201602629RA/en unknown
- 2014-10-22 KR KR1020217005338A patent/KR102358356B1/ko active Active
- 2014-10-22 EP EP14855668.1A patent/EP3060645B1/en active Active
-
2016
- 2016-04-21 IL IL245254A patent/IL245254B/en active IP Right Grant
-
2018
- 2018-05-25 US US15/989,549 patent/US10646871B2/en active Active
-
2019
- 2019-07-12 JP JP2019129854A patent/JP6944490B2/ja active Active
- 2019-11-14 US US16/683,798 patent/US11565259B2/en active Active
- 2019-12-06 AU AU2019275650A patent/AU2019275650B2/en active Active
-
2021
- 2021-09-10 JP JP2021147377A patent/JP7333365B2/ja active Active
-
2022
- 2022-02-02 AU AU2022200683A patent/AU2022200683B2/en active Active
- 2022-12-19 US US18/068,207 patent/US20230347347A1/en active Pending
-
2023
- 2023-06-02 JP JP2023091448A patent/JP2023115034A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2016536983A5 (cg-RX-API-DMAC7.html) | ||
| ES2390800T3 (es) | Aparatos y métodos para manipular gotitas en una placa de circuito impreso | |
| US10376886B2 (en) | Micro-fluidic devices for assaying biological activity | |
| CN108796038B (zh) | 一种核酸一体化检测方法及检测试剂管 | |
| EP3783094B1 (en) | Micro-fluidic devices for assaying biological activity | |
| CA2945395C (en) | Dep force control and electrowetting control in different sections of the same microfluidic apparatus | |
| Voldman et al. | A microfabrication-based dynamic array cytometer | |
| EP3060645B1 (en) | Microfluidic devices having isolation pens and methods of testing biological micro-objects with same | |
| Chai et al. | Capillarity enabled large‐array liquid metal electrodes for compact and high‐throughput dielectrophoretic microfluidics | |
| US11911763B2 (en) | Microfluidic device and methods | |
| US20170043343A1 (en) | Dep force control and electrowetting control in different sections of the same microfluidic apparatus | |
| EP3060926B1 (en) | Exporting a selected group of micro-objects from a micro-fluidic device | |
| US10308977B2 (en) | Device and method for processing a biological sample and analysis system for analyzing a biological specimen | |
| US20140348706A1 (en) | Microfluidic Device and Microfluidic System | |
| Vaidyanathan et al. | Microfluidics for cell sorting and single cell analysis from whole blood | |
| WO2013101672A2 (en) | Two dimensional nanofluidic ccd arrays for manipulation of charged molecules in solution | |
| CN104789443B (zh) | 一种细胞定位单元、阵列、器件及其形成方法 | |
| US20240189821A1 (en) | Method and Device for Trapping at Least One Nucleated Cell Using at Least One Electrode for a Microfluidic Device | |
| Tirapu-Azpiroz et al. | Dielectrophoretic microbead sorting using modular electrode design and capillary-driven microfluidics | |
| US11446666B2 (en) | Fluid handling device | |
| Kuroda et al. | Microfluidic sedimentation system for separation of plasma from whole blood | |
| WO2015125158A2 (en) | A micro-droplet array for multiple screening of a sample | |
| JP6238397B2 (ja) | 細胞空間分画装置および微細構造刃 | |
| CN117500600A (zh) | 用于使用针对微流体设备的至少一个电极捕获至少一个有核细胞的方法和装置 | |
| HK1228500B (en) | Exporting a selected group of micro-objects from a micro-fluidic device |