JP2016536360A5 - - Google Patents
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- JP2016536360A5 JP2016536360A5 JP2016550994A JP2016550994A JP2016536360A5 JP 2016536360 A5 JP2016536360 A5 JP 2016536360A5 JP 2016550994 A JP2016550994 A JP 2016550994A JP 2016550994 A JP2016550994 A JP 2016550994A JP 2016536360 A5 JP2016536360 A5 JP 2016536360A5
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- JP
- Japan
- Prior art keywords
- substituted
- unsubstituted
- alkyl
- compound
- pharmaceutical composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP20130191457 EP2868662A1 (en) | 2013-11-04 | 2013-11-04 | Stable pantetheine derivatives for the treatment of pantothenate kinase associated neurodegeneration (pkan) and methods for the synthesis of such compounds |
| EP13191457.4 | 2013-11-04 | ||
| PCT/EP2014/073258 WO2015063177A1 (en) | 2013-11-04 | 2014-10-29 | Stable pantetheine derivatives for the treatment of pantothenate kinase associated neurodegeneration (pkan) and methods for the synthesis of such compounds |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016536360A JP2016536360A (ja) | 2016-11-24 |
| JP2016536360A5 true JP2016536360A5 (enExample) | 2017-12-21 |
| JP6568536B2 JP6568536B2 (ja) | 2019-08-28 |
Family
ID=49518786
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016550994A Expired - Fee Related JP6568536B2 (ja) | 2013-11-04 | 2014-10-29 | パントテン酸キナーゼ関連神経変性症（ｐｋａｎ）の治療のための安定なパンテテイン誘導体およびそのような化合物の合成方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US9963472B2 (enExample) |
| EP (2) | EP2868662A1 (enExample) |
| JP (1) | JP6568536B2 (enExample) |
| CN (1) | CN105764909B (enExample) |
| AU (1) | AU2014343730B2 (enExample) |
| CA (1) | CA2929369C (enExample) |
| DK (1) | DK3066106T3 (enExample) |
| ES (1) | ES2743921T3 (enExample) |
| WO (1) | WO2015063177A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI24899A (sl) * | 2014-12-23 | 2016-06-30 | Acies Bio D.O.O. | Fosfopanteteinske spojine,same ali v kombinaciji z inhibitorji HMG-COA reduktaze za zniževanje serumskega holesterola in serumskih trigliceridov |
| EP3386995A1 (en) * | 2015-12-08 | 2018-10-17 | Retrophin, Inc. | Cyclic phosphates and cyclic phosphoramidates for the treatment of neurologic disorders |
| EP3471828A1 (en) | 2016-06-16 | 2019-04-24 | Acies Bio d.o.o. | Compositions and methods useful for treating diseases characterized by insufficient pantothenate kinase activity |
| JP2019523259A (ja) * | 2016-07-25 | 2019-08-22 | レトロフィン， インコーポレイテッド | 神経性障害の処置のためのパンテテイン誘導体 |
| CN106365998A (zh) * | 2016-08-19 | 2017-02-01 | 陕西思尔生物科技有限公司 | 一种特戊酸碘甲酯的制备方法 |
| CN107422056B (zh) * | 2017-08-17 | 2020-04-24 | 山东裕欣药业有限公司 | 一种特戊酸碘甲酯的气相色谱检测方法及其制备方法 |
| AU2019389168A1 (en) * | 2018-11-30 | 2021-06-24 | Comet Therapeutics, Inc. | Pantetheine derivatives and uses thereof |
| CN115919822A (zh) * | 2022-10-12 | 2023-04-07 | 深圳大学 | 泛硫乙胺在治疗阿尔茨海默病中的应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE532299A (enExample) * | 1953-10-07 | |||
| AU2002326412A1 (en) | 2001-07-20 | 2003-03-03 | Oregon Health And Science University | Novel human nucleic acids encoding a pantothenate kinase and methods of use |
| WO2012017400A1 (en) | 2010-08-03 | 2012-02-09 | North-West University | Synthesis of acyl-pantetheine derivatives and the use thereof in the synthesis of acyl-coenzyme a derivatives |
| SI3112372T1 (sl) * | 2012-04-27 | 2019-04-30 | Retrophin, Inc. | Derivati pantotenata za zdravljenje nevroloških motenj |
-
2013
- 2013-11-04 EP EP20130191457 patent/EP2868662A1/en not_active Withdrawn
-
2014
- 2014-10-29 US US15/034,244 patent/US9963472B2/en not_active Expired - Fee Related
- 2014-10-29 CN CN201480060274.8A patent/CN105764909B/zh active Active
- 2014-10-29 EP EP14790616.8A patent/EP3066106B1/en active Active
- 2014-10-29 CA CA2929369A patent/CA2929369C/en active Active
- 2014-10-29 DK DK14790616.8T patent/DK3066106T3/da active
- 2014-10-29 ES ES14790616T patent/ES2743921T3/es active Active
- 2014-10-29 AU AU2014343730A patent/AU2014343730B2/en not_active Ceased
- 2014-10-29 WO PCT/EP2014/073258 patent/WO2015063177A1/en not_active Ceased
- 2014-10-29 JP JP2016550994A patent/JP6568536B2/ja not_active Expired - Fee Related
-
2017
- 2017-12-21 US US15/850,252 patent/US20180118767A1/en not_active Abandoned
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