JP2016535019A5 - - Google Patents

Download PDF

Info

Publication number
JP2016535019A5
JP2016535019A5 JP2016525563A JP2016525563A JP2016535019A5 JP 2016535019 A5 JP2016535019 A5 JP 2016535019A5 JP 2016525563 A JP2016525563 A JP 2016525563A JP 2016525563 A JP2016525563 A JP 2016525563A JP 2016535019 A5 JP2016535019 A5 JP 2016535019A5
Authority
JP
Japan
Prior art keywords
adenosine
pain
methyl
group
bromothien
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2016525563A
Other languages
English (en)
Japanese (ja)
Other versions
JP2016535019A (ja
JP6534997B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2014/061734 external-priority patent/WO2015061426A1/en
Publication of JP2016535019A publication Critical patent/JP2016535019A/ja
Publication of JP2016535019A5 publication Critical patent/JP2016535019A5/ja
Application granted granted Critical
Publication of JP6534997B2 publication Critical patent/JP6534997B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2016525563A 2013-10-23 2014-10-22 神経変性疾患及び疼痛の予防及び治療における使用のための化合物 Active JP6534997B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361894699P 2013-10-23 2013-10-23
US61/894,699 2013-10-23
PCT/US2014/061734 WO2015061426A1 (en) 2013-10-23 2014-10-22 Compounds for use in prevention and treatment of neurodegenerative diseases and pain

Publications (3)

Publication Number Publication Date
JP2016535019A JP2016535019A (ja) 2016-11-10
JP2016535019A5 true JP2016535019A5 (enExample) 2017-11-09
JP6534997B2 JP6534997B2 (ja) 2019-06-26

Family

ID=52993493

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016525563A Active JP6534997B2 (ja) 2013-10-23 2014-10-22 神経変性疾患及び疼痛の予防及び治療における使用のための化合物

Country Status (14)

Country Link
US (1) US10301348B2 (enExample)
EP (1) EP3060566B1 (enExample)
JP (1) JP6534997B2 (enExample)
KR (1) KR102313314B1 (enExample)
CN (1) CN106414456B (enExample)
AU (1) AU2014340114B2 (enExample)
BR (1) BR112016008901B1 (enExample)
CA (1) CA2927699C (enExample)
IL (1) IL245103B (enExample)
MX (1) MX367707B (enExample)
RU (1) RU2695358C2 (enExample)
SG (1) SG11201603063WA (enExample)
WO (1) WO2015061426A1 (enExample)
ZA (1) ZA201603118B (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CR20170544A (es) 2015-05-29 2018-03-20 Univ Nat Yang Ming Agentes nucleosidos para la reducción de la actividad perjudicial de los genes que contienen repeticiones de nucleótidos extendidas.
WO2018140734A1 (en) 2017-01-27 2018-08-02 Academia Sinica Compound with analgesic effect for use in prevention and treatment of pain
AU2023219172B2 (en) * 2022-02-10 2026-02-19 Academia Sinica Method of treating spinal cord injury and composition for use therein
JP2025520975A (ja) * 2022-07-07 2025-07-03 中央研究院 統合失調症を治療する方法及びそれにおける使用のための組成物
AU2023416981A1 (en) * 2022-12-29 2025-06-12 Academia Sinica Method of treating sleep disruptions and composition for use therein
TW202500138A (zh) * 2023-03-17 2025-01-01 中央研究院 治療結節性硬化症或癲癇之方法及用於其中之組成物

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU8274187A (en) * 1986-10-31 1988-05-25 Warner-Lambert Company Heteroaromatic derivatives of adenosine
US5034381A (en) * 1988-01-07 1991-07-23 Ciba-Geigy Corporation 2-(substituted amino) adenosines as antihypertensives
CA2092305C (en) * 1990-09-25 2003-02-11 Alfred P. Spada Compounds having antihypertensive and anti-ischemic properties
US5561134A (en) * 1990-09-25 1996-10-01 Rhone-Poulenc Rorer Pharmaceuticals Inc. Compounds having antihypertensive, cardioprotective, anti-ischemic and antilipolytic properties
UY27939A1 (es) * 2002-08-21 2004-03-31 Glaxo Group Ltd Compuestos
CN106377540B (zh) * 2009-11-13 2019-08-16 中央研究院 预防及治疗神经退化疾病的双功能化合物
CA2783859A1 (en) 2009-12-10 2011-06-16 Institute Of Materia Medica, Chinese Academy Of Medical Sciences N6-substituted adenosine derivatives and n6-substituted adenine derivatives and uses thereof
AU2013216773B2 (en) 2012-02-09 2016-06-09 Brandbumps, Llc Decorative detectable warning panel having improved grip
CN104363757B (zh) * 2012-02-11 2017-05-24 中央研究院 治疗疼痛的方法及组合物

Similar Documents

Publication Publication Date Title
CA2813183C (en) Morpholino nucleic acid derivatives
US9879096B2 (en) Process for preparation of sugammadex sodium
JP7334228B2 (ja) 細胞毒性ベンゾジアゼピン誘導体の調製方法
JP2017538712A5 (enExample)
JP2015051994A5 (enExample)
US10654884B2 (en) Purine derivatives as CD73 inhibitors for the treatment of cancer
WO2016041508A1 (zh) 一种噁唑烷酮类化合物及其中间体的制备方法
JP2016536316A5 (enExample)
EP3083630B1 (en) Process methods for phosphatidylinositol 3-kinase inhibitors
JP2016503391A5 (enExample)
JP2015508092A5 (enExample)
JP2018502077A5 (enExample)
JP2016537346A5 (enExample)
JP2010529986A5 (enExample)
RU2016118282A (ru) Соединения для предотвращения и лечения нейродегенеративных заболеваний и боли
EP3083580A1 (en) A process for preparation of trelagliptin succinate
KR20170129264A (ko) 글리코시드 화합물의 제조 방법
JP2021500354A5 (enExample)
CN102958931B (zh) 碳环核苷和其中使用的中间体的合成方法
JP2014516968A5 (enExample)
CN107074858A (zh) 制备(2s,5r)‑6‑(苄氧基)‑7‑氧代‑1,6‑二氮杂二环[3.2.1]辛烷‑2‑羧酸钠的方法
CN101939289A (zh) 用于制备伏立诺他的新方法
US20180258091A1 (en) Process for manufacture of forodesine
CN103087080B (zh) 一种盐酸头孢卡品酯的制备方法及其合成中间体
JPH069650A (ja) セフェムプロドラッグエステルの製造方法