JP2016532632A5 - - Google Patents
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- Publication number
- JP2016532632A5 JP2016532632A5 JP2016515425A JP2016515425A JP2016532632A5 JP 2016532632 A5 JP2016532632 A5 JP 2016532632A5 JP 2016515425 A JP2016515425 A JP 2016515425A JP 2016515425 A JP2016515425 A JP 2016515425A JP 2016532632 A5 JP2016532632 A5 JP 2016532632A5
- Authority
- JP
- Japan
- Prior art keywords
- fibrosis
- pharmaceutically acceptable
- pharmaceutically
- stereoisomers
- pharmaceutical composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000001875 compounds Chemical class 0.000 claims 9
- 150000003839 salts Chemical class 0.000 claims 8
- 239000011780 sodium chloride Substances 0.000 claims 8
- 206010016654 Fibrosis Diseases 0.000 claims 6
- 230000004761 fibrosis Effects 0.000 claims 6
- 239000003795 chemical substances by application Substances 0.000 claims 5
- 239000008194 pharmaceutical composition Substances 0.000 claims 5
- 206010020772 Hypertension Diseases 0.000 claims 3
- 230000001225 therapeutic Effects 0.000 claims 3
- 206010028594 Myocardial fibrosis Diseases 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 201000002793 renal fibrosis Diseases 0.000 claims 2
- 206010065918 Prehypertension Diseases 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 239000000546 pharmaceutic aid Substances 0.000 claims 1
- 201000011461 pre-eclampsia Diseases 0.000 claims 1
Claims (10)
- 式:
- 化合物が、式:
- 請求項1又は2に記載の化合物又はその立体異性体若しくは医薬として許容される塩と、医薬として許容される賦形剤とを含む医薬組成物。
- 請求項1又は2に記載の化合物若しくはその立体異性体若しくは医薬として許容される塩、又は請求項3に記載の組成物を含む、高血圧又は高血圧前症の治療的処置薬。
- 請求項1又は2に記載の化合物若しくはその立体異性体若しくは医薬として許容される塩、又は請求項3に記載の医薬組成物を含む、線維症の予防的処置薬。
- 請求項1又は2に記載の化合物若しくはその立体異性体若しくは医薬として許容される塩、又は請求項3に記載の医薬組成物を含む、線維症の治療的処置薬。
- 請求項1又は2に記載の化合物若しくはその立体異性体若しくは医薬として許容される塩、又は請求項3に記載の医薬組成物を含む、高血圧及び線維症の治療的処置薬。
- 請求項1又は2に記載の化合物若しくはその立体異性体若しくは医薬として許容される塩、又は請求項3に記載の医薬組成物を含む、高血圧前症及び線維症の処置薬。
- 線維症が心筋線維症又は腎線維症である、請求項5〜8のいずれか1項に記載の処置薬。
- 線維症が心筋線維症及び腎線維症である、請求項5〜8のいずれか1項に記載の処置薬。
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2013903573A AU2013903573A0 (en) | 2013-09-17 | Compositions for the treatment of hypertension and/or fibrosis | |
| AU2013903573 | 2013-09-17 | ||
| PCT/AU2014/000923 WO2015039173A1 (en) | 2013-09-17 | 2014-09-17 | Compositions for the treatment of hypertension and/or fibrosis |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016532632A JP2016532632A (ja) | 2016-10-20 |
| JP2016532632A5 true JP2016532632A5 (ja) | 2016-12-08 |
| JP6122548B2 JP6122548B2 (ja) | 2017-04-26 |
Family
ID=52687998
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016515425A Active JP6122548B2 (ja) | 2013-09-17 | 2014-09-17 | 高血圧及び／又は線維症の処置用組成物 |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US9458093B2 (ja) |
| EP (1) | EP3046901B1 (ja) |
| JP (1) | JP6122548B2 (ja) |
| KR (1) | KR101736416B1 (ja) |
| CN (1) | CN105683152B (ja) |
| AP (1) | AP2016009079A0 (ja) |
| AU (1) | AU2014324078B2 (ja) |
| BR (1) | BR112016005601B1 (ja) |
| CA (1) | CA2924356C (ja) |
| DK (1) | DK3046901T3 (ja) |
| ES (1) | ES2655455T3 (ja) |
| IL (1) | IL244621A (ja) |
| MX (1) | MX368865B (ja) |
| MY (1) | MY172557A (ja) |
| NO (1) | NO3046901T3 (ja) |
| NZ (1) | NZ717927A (ja) |
| PH (1) | PH12016500497A1 (ja) |
| PL (1) | PL3046901T3 (ja) |
| RU (1) | RU2635564C2 (ja) |
| SG (1) | SG11201601642WA (ja) |
| UA (1) | UA118111C2 (ja) |
| WO (1) | WO2015039173A1 (ja) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9956166B2 (en) | 2013-09-18 | 2018-05-01 | Sorrento Therapeutics, Inc. | Methods for administration and methods for treating cardiovascular diseases with resiniferatoxin |
| WO2016145478A1 (en) * | 2015-03-18 | 2016-09-22 | Vectus Biosystems Limited | Compositions for the treatment of kidney and/or liver disease |
| JP6734294B2 (ja) * | 2015-03-18 | 2020-08-05 | ヴェクタス バイオシステムズ リミテッド | 線維症及び線維症に関連する状態の処置のための組成物 |
| US10752578B2 (en) | 2015-09-22 | 2020-08-25 | Vectus Biosystems Limited | Synthesis of terphenyl compounds |
| IL298314A (en) * | 2016-04-13 | 2023-01-01 | Univ Nebraska | Methods for administration and methods for treating cardiovascular diseases with resiniparatoxin |
| NZ750495A (en) * | 2016-07-28 | 2022-07-01 | Vectus Biosystems Ltd | Compositions for the treatment of pulmonary fibrosis |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2694288B1 (fr) * | 1992-06-30 | 1994-09-09 | Rhone Poulenc Agrochimie | Phenylbenzamides fongicides et procédés pour les préparer. |
| KR20140057411A (ko) * | 2004-06-11 | 2014-05-12 | 벡투스 바이오시스템즈 피티와이 리미티드 | 심혈관 질환의 치료를 위한 조성물 및 방법 |
| US8470778B2 (en) * | 2005-12-09 | 2013-06-25 | Vectus Biosystems Limited | VIP fragments and methods of use |
| US20120088737A2 (en) * | 2009-10-02 | 2012-04-12 | Ajinomoto Co., Inc | Novel acyl guanidine derivatives |
| UA117254C2 (uk) * | 2013-09-17 | 2018-07-10 | Вектус Байосистемз Лімітед | Композиція (варіанти) для лікування гіпертензії та/або фіброзу |
-
2014
- 2014-09-17 ES ES14845373.1T patent/ES2655455T3/es active Active
- 2014-09-17 UA UAA201602267A patent/UA118111C2/uk unknown
- 2014-09-17 NO NO14845373A patent/NO3046901T3/no unknown
- 2014-09-17 KR KR1020167008664A patent/KR101736416B1/ko active IP Right Grant
- 2014-09-17 EP EP14845373.1A patent/EP3046901B1/en active Active
- 2014-09-17 NZ NZ717927A patent/NZ717927A/en unknown
- 2014-09-17 PL PL14845373T patent/PL3046901T3/pl unknown
- 2014-09-17 JP JP2016515425A patent/JP6122548B2/ja active Active
- 2014-09-17 WO PCT/AU2014/000923 patent/WO2015039173A1/en active Application Filing
- 2014-09-17 BR BR112016005601-9A patent/BR112016005601B1/pt active IP Right Grant
- 2014-09-17 AP AP2016009079A patent/AP2016009079A0/xx unknown
- 2014-09-17 RU RU2016112257A patent/RU2635564C2/ru active
- 2014-09-17 US US15/022,278 patent/US9458093B2/en active Active
- 2014-09-17 DK DK14845373.1T patent/DK3046901T3/en active
- 2014-09-17 CA CA2924356A patent/CA2924356C/en active Active
- 2014-09-17 MX MX2016003371A patent/MX368865B/es active IP Right Grant
- 2014-09-17 AU AU2014324078A patent/AU2014324078B2/en active Active
- 2014-09-17 MY MYPI2016000482A patent/MY172557A/en unknown
- 2014-09-17 SG SG11201601642WA patent/SG11201601642WA/en unknown
- 2014-09-17 CN CN201480050979.1A patent/CN105683152B/zh active Active
-
2016
- 2016-03-14 PH PH12016500497A patent/PH12016500497A1/en unknown
- 2016-03-16 IL IL244621A patent/IL244621A/en active IP Right Grant
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