JP2016530236A5 - - Google Patents
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- Publication number
- JP2016530236A5 JP2016530236A5 JP2016524801A JP2016524801A JP2016530236A5 JP 2016530236 A5 JP2016530236 A5 JP 2016530236A5 JP 2016524801 A JP2016524801 A JP 2016524801A JP 2016524801 A JP2016524801 A JP 2016524801A JP 2016530236 A5 JP2016530236 A5 JP 2016530236A5
- Authority
- JP
- Japan
- Prior art keywords
- rotavirus
- protein
- adapter
- surface protein
- particles
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 241000702670 Rotavirus Species 0.000 claims description 81
- 102000018697 Membrane Proteins Human genes 0.000 claims description 57
- 108010052285 Membrane Proteins Proteins 0.000 claims description 57
- 102000004169 proteins and genes Human genes 0.000 claims description 41
- 108090000623 proteins and genes Proteins 0.000 claims description 41
- 239000002245 particle Substances 0.000 claims description 38
- 229920001184 polypeptide Polymers 0.000 claims description 37
- 102000004196 processed proteins & peptides Human genes 0.000 claims description 37
- 108090000765 processed proteins & peptides Proteins 0.000 claims description 37
- 238000000034 method Methods 0.000 claims description 23
- 150000007523 nucleic acids Chemical class 0.000 claims description 16
- 108020004707 nucleic acids Proteins 0.000 claims description 14
- 102000039446 nucleic acids Human genes 0.000 claims description 14
- 125000003275 alpha amino acid group Chemical group 0.000 claims description 12
- 108020001507 fusion proteins Proteins 0.000 claims description 12
- 102000037865 fusion proteins Human genes 0.000 claims description 12
- 108700026244 Open Reading Frames Proteins 0.000 claims description 10
- 239000000203 mixture Substances 0.000 claims description 10
- 239000000725 suspension Substances 0.000 claims description 10
- 210000004027 cell Anatomy 0.000 claims description 7
- 239000001963 growth medium Substances 0.000 claims description 7
- 238000010367 cloning Methods 0.000 claims description 4
- 230000008014 freezing Effects 0.000 claims description 4
- 238000007710 freezing Methods 0.000 claims description 4
- 238000003384 imaging method Methods 0.000 claims description 4
- 238000001000 micrograph Methods 0.000 claims description 4
- 230000001902 propagating effect Effects 0.000 claims description 4
- 230000003612 virological effect Effects 0.000 claims description 4
- 102000000844 Cell Surface Receptors Human genes 0.000 claims description 3
- 108010001857 Cell Surface Receptors Proteins 0.000 claims description 3
- 108091028043 Nucleic acid sequence Proteins 0.000 claims description 2
- 239000012634 fragment Substances 0.000 claims description 2
- 239000002773 nucleotide Substances 0.000 claims description 2
- 125000003729 nucleotide group Chemical group 0.000 claims description 2
- 230000004927 fusion Effects 0.000 claims 2
- PXFBZOLANLWPMH-UHFFFAOYSA-N 16-Epiaffinine Natural products C1C(C2=CC=CC=C2N2)=C2C(=O)CC2C(=CC)CN(C)C1C2CO PXFBZOLANLWPMH-UHFFFAOYSA-N 0.000 description 1
- 230000004709 cell invasion Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 239000002609 medium Substances 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 238000010845 search algorithm Methods 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13175637 | 2013-07-08 | ||
| EP13175637.1 | 2013-07-08 | ||
| PCT/EP2014/064652 WO2015004158A1 (en) | 2013-07-08 | 2014-07-08 | Rotavirus particles with chimeric surface proteins |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016530236A JP2016530236A (ja) | 2016-09-29 |
| JP2016530236A5 true JP2016530236A5 (cg-RX-API-DMAC7.html) | 2017-08-10 |
| JP6594306B2 JP6594306B2 (ja) | 2019-10-23 |
Family
ID=48747990
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016524801A Active JP6594306B2 (ja) | 2013-07-08 | 2014-07-08 | キメラ表面タンパク質を有するロタウイルス粒子 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US10192025B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3019518B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP6594306B2 (cg-RX-API-DMAC7.html) |
| CN (1) | CN105518022B (cg-RX-API-DMAC7.html) |
| AU (1) | AU2014289274B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2916827C (cg-RX-API-DMAC7.html) |
| ES (1) | ES2733279T3 (cg-RX-API-DMAC7.html) |
| MX (1) | MX367150B (cg-RX-API-DMAC7.html) |
| RU (1) | RU2698049C2 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2015004158A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SMT202000101T1 (it) * | 2008-10-10 | 2020-03-13 | Childrens Medical Center | Vaccino con trimero di env di hiv-1 stabilizzato biochimicamente |
| MY187152A (en) | 2013-01-07 | 2021-09-06 | Beth Israel Deaconess Medical Ct Inc | Stabilized human immunodeficiency virus (hiv) envelope (env) trimer vaccines and methods of using same |
| EP3069730A3 (en) | 2015-03-20 | 2017-03-15 | International Aids Vaccine Initiative | Soluble hiv-1 envelope glycoprotein trimers |
| US9931394B2 (en) | 2015-03-23 | 2018-04-03 | International Aids Vaccine Initiative | Soluble HIV-1 envelope glycoprotein trimers |
| EP3368068B1 (en) * | 2015-10-30 | 2020-11-18 | University of Copenhagen | Virus like particle with efficient epitope display |
| MA44418B1 (fr) * | 2017-03-02 | 2021-11-30 | Intelligent Virus Imaging Inc | Procédé permettant la mesure quantitative de contenu particulaire à l'aide d'une imagerie à l'état hydraté |
| CN109627295B (zh) * | 2018-12-29 | 2020-08-04 | 四川大学 | 一种通用型狂犬病相关病毒g蛋白胞外段的制备方法 |
| CN110144334B (zh) * | 2019-05-05 | 2021-03-16 | 中国水产科学研究院长江水产研究所 | 一种共表达草鱼呼肠孤病毒外衣壳蛋白vp4和vp35的重组杆状病毒的制备方法和应用 |
| CN110408637B (zh) * | 2019-08-08 | 2020-12-25 | 中国水产科学研究院长江水产研究所 | 一种草鱼出血病酵母口服疫苗及应用 |
| CN114316009B (zh) * | 2020-09-29 | 2023-04-25 | 上海交通大学 | 一种能够结合多种病毒的蛋白及其应用 |
| CN115044597A (zh) * | 2022-07-22 | 2022-09-13 | 态创生物科技(广州)有限公司 | 基于噬菌体展示和蛋白酶切割的寡肽表达和提纯方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0235754A2 (en) | 1986-03-04 | 1987-09-09 | Abbott Laboratories | Composition and methods of use for a lacZ rotavirus fusion protein |
| CA1340876C (en) | 1987-08-10 | 2000-01-18 | Michael Leigh Dyall-Smith | The vp7 gene of human rotavirus 4 |
| ZA929418B (en) * | 1991-12-06 | 1993-06-07 | Whitehead Biomedical Inst | Recombinant vaccines and method of producing same. |
| WO2006007555A2 (en) * | 2004-07-01 | 2006-01-19 | Children's Medical Center Corporation ¨ | Rotavirus antigens |
| EP1960525B1 (en) | 2005-09-09 | 2013-04-24 | Zymogenetics, Inc. | Method for preparing trimeric proteins |
| KR101502619B1 (ko) | 2007-03-29 | 2015-03-16 | 한국엠에스디 유한회사 | 인간로타바이러스의 ｖｐ７ 유전자 및 이에 특이적인프라이머 또는 프로브를 포함하는 인간로타바이러스 감염증진단용 조성물 |
| CN102465137B (zh) | 2010-11-05 | 2014-03-12 | 上海生物制品研究所有限责任公司 | 表达轮状病毒类表达颗粒的毕赤酵母、其制备方法及用途 |
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2014
- 2014-07-08 EP EP14736835.1A patent/EP3019518B1/en active Active
- 2014-07-08 WO PCT/EP2014/064652 patent/WO2015004158A1/en not_active Ceased
- 2014-07-08 CN CN201480049500.2A patent/CN105518022B/zh active Active
- 2014-07-08 CA CA2916827A patent/CA2916827C/en active Active
- 2014-07-08 JP JP2016524801A patent/JP6594306B2/ja active Active
- 2014-07-08 RU RU2016103770A patent/RU2698049C2/ru active
- 2014-07-08 US US14/900,829 patent/US10192025B2/en active Active
- 2014-07-08 MX MX2016000075A patent/MX367150B/es active IP Right Grant
- 2014-07-08 ES ES14736835T patent/ES2733279T3/es active Active
- 2014-07-08 AU AU2014289274A patent/AU2014289274B2/en active Active