JP2016524592A5 - - Google Patents
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- Publication number
- JP2016524592A5 JP2016524592A5 JP2016509455A JP2016509455A JP2016524592A5 JP 2016524592 A5 JP2016524592 A5 JP 2016524592A5 JP 2016509455 A JP2016509455 A JP 2016509455A JP 2016509455 A JP2016509455 A JP 2016509455A JP 2016524592 A5 JP2016524592 A5 JP 2016524592A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- icosl
- specific antigen
- binding molecule
- fusion protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361815043P | 2013-04-23 | 2013-04-23 | |
| US61/815,043 | 2013-04-23 | ||
| PCT/EP2014/058276 WO2014173975A1 (en) | 2013-04-23 | 2014-04-23 | Isolation of therapeutic target specific vnar domains to icosl |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016524592A JP2016524592A (ja) | 2016-08-18 |
| JP2016524592A5 true JP2016524592A5 (enExample) | 2017-06-01 |
| JP6591964B2 JP6591964B2 (ja) | 2019-10-16 |
Family
ID=50543598
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016509450A Active JP6616284B2 (ja) | 2013-04-23 | 2014-04-23 | 特異的結合分子の人工ライブラリー |
| JP2016509455A Active JP6591964B2 (ja) | 2013-04-23 | 2014-04-23 | Ｉｃｏｓｌへの治療上の標的特異的ｖｎａｒドメインの単離 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016509450A Active JP6616284B2 (ja) | 2013-04-23 | 2014-04-23 | 特異的結合分子の人工ライブラリー |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US10202438B2 (enExample) |
| EP (3) | EP2989204B1 (enExample) |
| JP (2) | JP6616284B2 (enExample) |
| KR (2) | KR102320189B1 (enExample) |
| CN (2) | CN105492610B (enExample) |
| AU (3) | AU2014257565A1 (enExample) |
| BR (2) | BR112015026729A2 (enExample) |
| CA (2) | CA2909921C (enExample) |
| DK (1) | DK2989203T3 (enExample) |
| RU (2) | RU2015146419A (enExample) |
| WO (2) | WO2014173959A2 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013167883A1 (en) | 2012-05-07 | 2013-11-14 | The University Court Of The University Of Aberdeen | Single domain binding molecule |
| JP6616284B2 (ja) | 2013-04-23 | 2019-12-04 | ザ ユニバーシティ コート オブ ザ ユニバーシティ オブ アバディーン | 特異的結合分子の人工ライブラリー |
| CA2953569A1 (en) | 2014-06-26 | 2015-12-30 | Ossianix, Inc. | Semi-synthetic nurse shark vnar libraries for making and using selective binding compounds |
| CN107074961A (zh) * | 2014-11-03 | 2017-08-18 | 默克专利股份公司 | 用于生成双特异性鲨鱼可变抗体结构域的方法及其用途 |
| EP3218411B1 (en) | 2014-11-14 | 2022-01-12 | Ossianix, Inc. | Variable new antigen receptors (vnars) directed against transferrin receptor (tfr) and their use |
| ITUB20151014A1 (it) | 2015-05-27 | 2016-11-27 | Univ Degli Studi Del Piemonte Orientale Amedeo Avogadro | Ligandi del recettore b7h nel trattamento di osteopenia e osteoporosi |
| SG11201808457PA (en) | 2016-04-15 | 2018-10-30 | Alpine Immune Sciences Inc | Icos ligand variant immunomodulatory proteins and uses thereof |
| CN107130300A (zh) * | 2016-10-08 | 2017-09-05 | 深圳劲宇生物科技有限公司 | 一种dna编码分子库的合成方法及dna模板 |
| EP3824906A1 (en) | 2016-12-21 | 2021-05-26 | Amgen Inc. | Anti-tnf alpha antibody formulations |
| EP3688030B1 (en) | 2017-09-27 | 2024-12-11 | Elasmogen Ltd | Specific binding molecules |
| US11180544B2 (en) * | 2017-11-07 | 2021-11-23 | City University Of Hong Kong | Method of producing antibody fragment |
| GB201721802D0 (en) | 2017-12-22 | 2018-02-07 | Almac Discovery Ltd | Ror1-specific antigen binding molecules |
| WO2020056327A1 (en) | 2018-09-14 | 2020-03-19 | Ossianix, Inc. | Tfr-specific binding moieties and transcytosis method to select vnars that cross cellular barriers |
| CN111197074B (zh) * | 2018-11-20 | 2023-08-15 | 深圳华大生命科学研究院 | 条纹斑竹鲨免疫球蛋白新抗原受体可变区库引物及应用 |
| US20220130494A1 (en) * | 2019-02-11 | 2022-04-28 | Neal W. Woodbury | Systems, methods, and media for molecule design using machine learning mechanisms |
| GB201906997D0 (en) * | 2019-05-17 | 2019-07-03 | Elasmogen Ltd | Conjugates |
| GB201908886D0 (en) * | 2019-06-20 | 2019-08-07 | Almac Discovery Ltd | Anthracycline derivatives |
| WO2021222546A1 (en) * | 2020-05-01 | 2021-11-04 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Compositions and methods for identifying nanobodies and nanobody affinities |
| CN112301431B (zh) * | 2020-08-12 | 2023-01-31 | 华东理工大学 | 基于鲨鱼抗体可变区v-nar的噬菌体文库及其构建方法 |
| GB202020152D0 (en) | 2020-12-18 | 2021-02-03 | Elasmogen Ltd | Fast-track humanisation of specific binding molecules |
| GB202020154D0 (en) * | 2020-12-18 | 2021-02-03 | Almac Discovery Ltd | ROR1-specific variant antigen binding molecules |
| WO2022212429A1 (en) * | 2021-03-31 | 2022-10-06 | Sachdev Sidhu | Anti-viral compositions for rift valley fever virus infections and methods of using same |
| EP4141028A1 (en) | 2021-08-31 | 2023-03-01 | Johann-Wolfgang-Goethe-Universität Frankfurt am Main | Personalized vnar-based chimeric antigen receptors (vnar-car) for the treatment of clonal b-and t cell malignancies, and methods for producing vnar-cars |
| GB202407865D0 (en) | 2024-06-03 | 2024-07-17 | Elasmogen Ltd | Self immolative compounds |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0008419D0 (en) * | 2000-04-05 | 2000-05-24 | Bioinvent Int Ab | A method for invitro molecular evolution of antibody function |
| AU2002319544B2 (en) * | 2001-08-10 | 2008-07-10 | Aberdeen University | Antigen binding domains from fish |
| JP4753578B2 (ja) | 2002-06-03 | 2011-08-24 | ジェネンテック， インコーポレイテッド | 合成抗体ファージライブラリー |
| US9321832B2 (en) | 2002-06-28 | 2016-04-26 | Domantis Limited | Ligand |
| EP1660186B1 (en) | 2003-08-18 | 2013-12-25 | MedImmune, LLC | Humanization of antibodies |
| DE602004032042D1 (de) | 2003-08-27 | 2011-05-12 | Proterec Ltd | Bibliotheken rekombinanter chimärischer proteine |
| WO2005118629A1 (en) * | 2004-06-02 | 2005-12-15 | Diatech Pty Ltd | BINDING MOIETIES BASED ON SHARK IgNAR DOMAINS |
| CA2569509C (en) * | 2004-06-03 | 2014-08-12 | Novimmune S.A. | Anti-cd3 antibodies and methods of use thereof |
| JPWO2006003999A1 (ja) | 2004-07-05 | 2008-07-31 | 財団法人化学及血清療法研究所 | ヒト抗ヒトｂ７ｒｐ−１抗体およびその抗体フラグメント |
| EP1869192B1 (en) * | 2005-03-18 | 2016-01-20 | MedImmune, LLC | Framework-shuffling of antibodies |
| US8293233B2 (en) * | 2005-03-25 | 2012-10-23 | National Research Council Of Canada | Method for isolation of soluble polypeptides |
| RU2464276C2 (ru) | 2005-05-18 | 2012-10-20 | Аблинкс Н.В. | Улучшенные нанотела против фактора некроза опухоли-альфа |
| SG196835A1 (en) | 2005-07-18 | 2014-02-13 | Amgen Inc | Human anti-b7rp1 neutralizing antibodies |
| EP2069402A2 (en) | 2006-09-08 | 2009-06-17 | Ablynx N.V. | Serum albumin binding proteins with long half-lives |
| AU2007306340A1 (en) | 2006-10-11 | 2008-04-17 | Ablynx N.V. | Amino acid sequences that bind to serum proteins in a manner that is essentially independent of the pH, compounds comprising the same, and use thereof |
| WO2009026638A1 (en) | 2007-08-31 | 2009-03-05 | Melbourne Health | Marine-animal derived therapeutic and diagnostic agents for hepatitis b |
| AU2009301631A1 (en) | 2008-10-06 | 2010-04-15 | Commonwealth Scientific And Industrial Research Organisation | Amyloid-beta peptide crystal structure |
| US20110231359A1 (en) * | 2008-10-07 | 2011-09-22 | Zap Holdings Limited | Synchronization of relational databases with olap cubes |
| US8496933B2 (en) * | 2009-11-04 | 2013-07-30 | Laboratorios Silanes, S.A. De C.V. | VHNAR anti-cytokine domains |
| US20140154241A1 (en) * | 2010-12-03 | 2014-06-05 | Cyclogenix Ltd | Binding peptides i |
| WO2013167883A1 (en) * | 2012-05-07 | 2013-11-14 | The University Court Of The University Of Aberdeen | Single domain binding molecule |
| CN103031304A (zh) * | 2012-12-27 | 2013-04-10 | 苏州大学 | 一种微小rna用于调控b7-h2基因表达 |
| JP6616284B2 (ja) | 2013-04-23 | 2019-12-04 | ザ ユニバーシティ コート オブ ザ ユニバーシティ オブ アバディーン | 特異的結合分子の人工ライブラリー |
-
2014
- 2014-04-23 JP JP2016509450A patent/JP6616284B2/ja active Active
- 2014-04-23 BR BR112015026729A patent/BR112015026729A2/pt not_active Application Discontinuation
- 2014-04-23 WO PCT/EP2014/058251 patent/WO2014173959A2/en not_active Ceased
- 2014-04-23 RU RU2015146419A patent/RU2015146419A/ru not_active Application Discontinuation
- 2014-04-23 KR KR1020157033430A patent/KR102320189B1/ko active Active
- 2014-04-23 BR BR112015026716A patent/BR112015026716A2/pt not_active IP Right Cessation
- 2014-04-23 AU AU2014257565A patent/AU2014257565A1/en not_active Abandoned
- 2014-04-23 RU RU2015146418A patent/RU2015146418A/ru not_active Application Discontinuation
- 2014-04-23 US US14/786,074 patent/US10202438B2/en active Active
- 2014-04-23 WO PCT/EP2014/058276 patent/WO2014173975A1/en not_active Ceased
- 2014-04-23 CA CA2909921A patent/CA2909921C/en active Active
- 2014-04-23 DK DK14718999.7T patent/DK2989203T3/da active
- 2014-04-23 JP JP2016509455A patent/JP6591964B2/ja active Active
- 2014-04-23 EP EP14720559.5A patent/EP2989204B1/en active Active
- 2014-04-23 EP EP19208141.2A patent/EP3683312B1/en active Active
- 2014-04-23 EP EP14718999.7A patent/EP2989203B1/en active Active
- 2014-04-23 KR KR1020157033307A patent/KR20160010466A/ko not_active Withdrawn
- 2014-04-23 CN CN201480035865.XA patent/CN105492610B/zh active Active
- 2014-04-23 CN CN201480035842.9A patent/CN105531370A/zh active Pending
- 2014-04-23 AU AU2014257549A patent/AU2014257549B2/en active Active
- 2014-04-23 US US14/785,975 patent/US10472410B2/en active Active
- 2014-04-23 CA CA2909923A patent/CA2909923A1/en not_active Abandoned
-
2019
- 2019-02-11 US US16/271,959 patent/US11459377B2/en active Active
- 2019-07-18 AU AU2019206064A patent/AU2019206064A1/en not_active Abandoned
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