JP2016524592A5 - - Google Patents
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- Publication number
- JP2016524592A5 JP2016524592A5 JP2016509455A JP2016509455A JP2016524592A5 JP 2016524592 A5 JP2016524592 A5 JP 2016524592A5 JP 2016509455 A JP2016509455 A JP 2016509455A JP 2016509455 A JP2016509455 A JP 2016509455A JP 2016524592 A5 JP2016524592 A5 JP 2016524592A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- icosl
- specific antigen
- binding molecule
- fusion protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361815043P | 2013-04-23 | 2013-04-23 | |
| US61/815,043 | 2013-04-23 | ||
| PCT/EP2014/058276 WO2014173975A1 (en) | 2013-04-23 | 2014-04-23 | Isolation of therapeutic target specific vnar domains to icosl |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016524592A JP2016524592A (ja) | 2016-08-18 |
| JP2016524592A5 true JP2016524592A5 (enExample) | 2017-06-01 |
| JP6591964B2 JP6591964B2 (ja) | 2019-10-16 |
Family
ID=50543598
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016509450A Active JP6616284B2 (ja) | 2013-04-23 | 2014-04-23 | 特異的結合分子の人工ライブラリー |
| JP2016509455A Active JP6591964B2 (ja) | 2013-04-23 | 2014-04-23 | Ｉｃｏｓｌへの治療上の標的特異的ｖｎａｒドメインの単離 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016509450A Active JP6616284B2 (ja) | 2013-04-23 | 2014-04-23 | 特異的結合分子の人工ライブラリー |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US10472410B2 (enExample) |
| EP (3) | EP3683312B1 (enExample) |
| JP (2) | JP6616284B2 (enExample) |
| KR (2) | KR20160010466A (enExample) |
| CN (2) | CN105531370A (enExample) |
| AU (3) | AU2014257549B2 (enExample) |
| BR (2) | BR112015026716A2 (enExample) |
| CA (2) | CA2909921C (enExample) |
| DK (1) | DK2989203T3 (enExample) |
| RU (2) | RU2015146418A (enExample) |
| WO (2) | WO2014173959A2 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20130302250A1 (en) | 2012-05-07 | 2013-11-14 | The University Court Of The University Of Aberdeen | Single domain binding molecule |
| EP3683312B1 (en) | 2013-04-23 | 2022-09-07 | Elasmogen Limited | Synthetic library of specific binding molecules |
| US10479990B2 (en) | 2014-06-26 | 2019-11-19 | Ossianix, Inc. | Semi-synthetic nurse shark VNAR libraries for making and using selective binding compounds |
| WO2016070959A1 (en) * | 2014-11-03 | 2016-05-12 | Merck Patent Gmbh | Methods for generating bispecific shark variable antibody domains and use thereof |
| CA2967830A1 (en) | 2014-11-14 | 2016-05-19 | Ossianix, Inc. | Tfr selective binding compounds and related methods |
| ITUB20151014A1 (it) * | 2015-05-27 | 2016-11-27 | Univ Degli Studi Del Piemonte Orientale Amedeo Avogadro | Ligandi del recettore b7h nel trattamento di osteopenia e osteoporosi |
| WO2017181148A2 (en) | 2016-04-15 | 2017-10-19 | Alpine Immune Sciences, Inc. | Icos ligand variant immunomodulatory proteins and uses thereof |
| CN107130300A (zh) * | 2016-10-08 | 2017-09-05 | 深圳劲宇生物科技有限公司 | 一种dna编码分子库的合成方法及dna模板 |
| EP4467565A3 (en) | 2016-12-21 | 2025-03-12 | Amgen Inc. | Anti-tnf alpha antibody formulations |
| EP3688030B1 (en) * | 2017-09-27 | 2024-12-11 | Elasmogen Ltd | Specific binding molecules |
| US11180544B2 (en) * | 2017-11-07 | 2021-11-23 | City University Of Hong Kong | Method of producing antibody fragment |
| GB201721802D0 (en) | 2017-12-22 | 2018-02-07 | Almac Discovery Ltd | Ror1-specific antigen binding molecules |
| US12351642B2 (en) | 2018-09-14 | 2025-07-08 | Ossianix, Inc. | TFR-specific binding moieties and transcytosis method to select VNARs that cross cellular barriers |
| CN111197074B (zh) * | 2018-11-20 | 2023-08-15 | 深圳华大生命科学研究院 | 条纹斑竹鲨免疫球蛋白新抗原受体可变区库引物及应用 |
| WO2020167872A1 (en) * | 2019-02-11 | 2020-08-20 | Woodbury Neal W | Systems, methods, and media for molecule design using machine learning mechanisms |
| GB201906997D0 (en) * | 2019-05-17 | 2019-07-03 | Elasmogen Ltd | Conjugates |
| GB201908886D0 (en) * | 2019-06-20 | 2019-08-07 | Almac Discovery Ltd | Anthracycline derivatives |
| JP7765090B2 (ja) * | 2020-05-01 | 2025-11-06 | ユニバーシティ オブ ピッツバーグ －オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション | ナノボディ及びナノボディ親和性を同定するための組成物及び方法 |
| CN112301431B (zh) * | 2020-08-12 | 2023-01-31 | 华东理工大学 | 基于鲨鱼抗体可变区v-nar的噬菌体文库及其构建方法 |
| GB202020152D0 (en) | 2020-12-18 | 2021-02-03 | Elasmogen Ltd | Fast-track humanisation of specific binding molecules |
| GB202020154D0 (en) * | 2020-12-18 | 2021-02-03 | Almac Discovery Ltd | ROR1-specific variant antigen binding molecules |
| WO2022212429A1 (en) * | 2021-03-31 | 2022-10-06 | Sachdev Sidhu | Anti-viral compositions for rift valley fever virus infections and methods of using same |
| EP4141028A1 (en) | 2021-08-31 | 2023-03-01 | Johann-Wolfgang-Goethe-Universität Frankfurt am Main | Personalized vnar-based chimeric antigen receptors (vnar-car) for the treatment of clonal b-and t cell malignancies, and methods for producing vnar-cars |
| GB202407865D0 (en) | 2024-06-03 | 2024-07-17 | Elasmogen Ltd | Self immolative compounds |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0008419D0 (en) | 2000-04-05 | 2000-05-24 | Bioinvent Int Ab | A method for invitro molecular evolution of antibody function |
| ES2337986T3 (es) | 2001-08-10 | 2010-05-03 | Aberdeen University | Dominios de union de antigenos de peces. |
| CA2488441C (en) | 2002-06-03 | 2015-01-27 | Genentech, Inc. | Synthetic antibody phage libraries |
| US9321832B2 (en) | 2002-06-28 | 2016-04-26 | Domantis Limited | Ligand |
| ES2458636T3 (es) * | 2003-08-18 | 2014-05-06 | Medimmune, Llc | Humanización de anticuerpos |
| US20050053989A1 (en) * | 2003-08-27 | 2005-03-10 | Gil Sharon | Libraries of recombinant chimeric proteins |
| WO2005118629A1 (en) * | 2004-06-02 | 2005-12-15 | Diatech Pty Ltd | BINDING MOIETIES BASED ON SHARK IgNAR DOMAINS |
| EA010350B1 (ru) * | 2004-06-03 | 2008-08-29 | Новиммун С.А. | Антитела против cd3 и способы их применения |
| WO2006003999A1 (ja) * | 2004-07-05 | 2006-01-12 | Juridical Foundation The Chemo-Sero-Therapeutic Research Institute | ヒト抗ヒトb7rp-1抗体およびその抗体フラグメント |
| CA2602035C (en) | 2005-03-18 | 2015-06-16 | Medimmune, Inc. | Framework-shuffling of antibodies |
| EP2339001A2 (en) | 2005-03-25 | 2011-06-29 | National Research Council of Canada | Method for isolation of soluble polypeptides |
| EP2949668B1 (en) | 2005-05-18 | 2019-08-14 | Ablynx N.V. | Improved nanobodies tm against tumor necrosis factor-alpha |
| RS54984B1 (sr) | 2005-07-18 | 2016-11-30 | Amgen Inc | Humana anti-b7rp1 neutrališuća antitela |
| EP2069402A2 (en) | 2006-09-08 | 2009-06-17 | Ablynx N.V. | Serum albumin binding proteins with long half-lives |
| EP2086998B1 (en) | 2006-10-11 | 2011-12-07 | Ablynx N.V. | Amino acid sequences that bind to serum proteins in a manner that is essentially independent of the ph, compounds comprising the same, and use thereof |
| WO2009026638A1 (en) | 2007-08-31 | 2009-03-05 | Melbourne Health | Marine-animal derived therapeutic and diagnostic agents for hepatitis b |
| EP2344545A4 (en) * | 2008-10-06 | 2012-10-03 | Commw Scient Ind Res Org | CRYSTALLINE STRUCTURE OF BETA-AMYLOID PEPTIDE |
| AU2009301630A1 (en) * | 2008-10-07 | 2010-04-15 | Zap Holdings Limited | Synchronization of relational databases with OLAP cubes |
| WO2011056056A2 (es) | 2009-11-04 | 2011-05-12 | Laboratorios Silanes, S.A. De C.V. | Dominios vhnar anti -citocinas |
| US20140154241A1 (en) * | 2010-12-03 | 2014-06-05 | Cyclogenix Ltd | Binding peptides i |
| US20130302250A1 (en) | 2012-05-07 | 2013-11-14 | The University Court Of The University Of Aberdeen | Single domain binding molecule |
| CN103031304A (zh) * | 2012-12-27 | 2013-04-10 | 苏州大学 | 一种微小rna用于调控b7-h2基因表达 |
| EP3683312B1 (en) | 2013-04-23 | 2022-09-07 | Elasmogen Limited | Synthetic library of specific binding molecules |
-
2014
- 2014-04-23 EP EP19208141.2A patent/EP3683312B1/en active Active
- 2014-04-23 CN CN201480035842.9A patent/CN105531370A/zh active Pending
- 2014-04-23 CA CA2909921A patent/CA2909921C/en active Active
- 2014-04-23 CN CN201480035865.XA patent/CN105492610B/zh active Active
- 2014-04-23 RU RU2015146418A patent/RU2015146418A/ru not_active Application Discontinuation
- 2014-04-23 US US14/785,975 patent/US10472410B2/en active Active
- 2014-04-23 BR BR112015026716A patent/BR112015026716A2/pt not_active IP Right Cessation
- 2014-04-23 BR BR112015026729A patent/BR112015026729A2/pt not_active Application Discontinuation
- 2014-04-23 WO PCT/EP2014/058251 patent/WO2014173959A2/en not_active Ceased
- 2014-04-23 JP JP2016509450A patent/JP6616284B2/ja active Active
- 2014-04-23 CA CA2909923A patent/CA2909923A1/en not_active Abandoned
- 2014-04-23 DK DK14718999.7T patent/DK2989203T3/da active
- 2014-04-23 KR KR1020157033307A patent/KR20160010466A/ko not_active Withdrawn
- 2014-04-23 US US14/786,074 patent/US10202438B2/en active Active
- 2014-04-23 AU AU2014257549A patent/AU2014257549B2/en active Active
- 2014-04-23 KR KR1020157033430A patent/KR102320189B1/ko active Active
- 2014-04-23 WO PCT/EP2014/058276 patent/WO2014173975A1/en not_active Ceased
- 2014-04-23 JP JP2016509455A patent/JP6591964B2/ja active Active
- 2014-04-23 AU AU2014257565A patent/AU2014257565A1/en not_active Abandoned
- 2014-04-23 RU RU2015146419A patent/RU2015146419A/ru not_active Application Discontinuation
- 2014-04-23 EP EP14718999.7A patent/EP2989203B1/en active Active
- 2014-04-23 EP EP14720559.5A patent/EP2989204B1/en active Active
-
2019
- 2019-02-11 US US16/271,959 patent/US11459377B2/en active Active
- 2019-07-18 AU AU2019206064A patent/AU2019206064A1/en not_active Abandoned
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