JP2016522243A5 - - Google Patents
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- Publication number
- JP2016522243A5 JP2016522243A5 JP2016520558A JP2016520558A JP2016522243A5 JP 2016522243 A5 JP2016522243 A5 JP 2016522243A5 JP 2016520558 A JP2016520558 A JP 2016520558A JP 2016520558 A JP2016520558 A JP 2016520558A JP 2016522243 A5 JP2016522243 A5 JP 2016522243A5
- Authority
- JP
- Japan
- Prior art keywords
- silica
- hydrogel composite
- less
- particles
- composite according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims 76
- 239000000377 silicon dioxide Substances 0.000 claims 30
- 239000002131 composite material Substances 0.000 claims 29
- 239000000017 hydrogel Substances 0.000 claims 27
- 229940079593 drug Drugs 0.000 claims 8
- 239000003814 drug Substances 0.000 claims 8
- 238000000034 method Methods 0.000 claims 8
- RMAQACBXLXPBSY-UHFFFAOYSA-N silicic acid Chemical compound O[Si](O)(O)O RMAQACBXLXPBSY-UHFFFAOYSA-N 0.000 claims 6
- 239000007787 solid Substances 0.000 claims 6
- 239000008186 active pharmaceutical agent Substances 0.000 claims 3
- 239000002245 particle Substances 0.000 claims 3
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 239000000835 fiber Substances 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 239000011859 microparticle Substances 0.000 claims 2
- 239000000725 suspension Substances 0.000 claims 2
- UIAGMCDKSXEBJQ-IBGZPJMESA-N 3-o-(2-methoxyethyl) 5-o-propan-2-yl (4s)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate Chemical compound COCCOC(=O)C1=C(C)NC(C)=C(C(=O)OC(C)C)[C@H]1C1=CC=CC([N+]([O-])=O)=C1 UIAGMCDKSXEBJQ-IBGZPJMESA-N 0.000 claims 1
- 239000013543 active substance Substances 0.000 claims 1
- GNBHRKFJIUUOQI-UHFFFAOYSA-N fluorescein Chemical compound O1C(=O)C2=CC=CC=C2C21C1=CC=C(O)C=C1OC1=CC(O)=CC=C21 GNBHRKFJIUUOQI-UHFFFAOYSA-N 0.000 claims 1
- 238000002513 implantation Methods 0.000 claims 1
- 238000001361 intraarterial administration Methods 0.000 claims 1
- 238000007918 intramuscular administration Methods 0.000 claims 1
- 238000007912 intraperitoneal administration Methods 0.000 claims 1
- 238000007916 intrasternal administration Methods 0.000 claims 1
- 238000007913 intrathecal administration Methods 0.000 claims 1
- 238000001990 intravenous administration Methods 0.000 claims 1
- 238000007914 intraventricular administration Methods 0.000 claims 1
- 229960000715 nimodipine Drugs 0.000 claims 1
- 230000010355 oscillation Effects 0.000 claims 1
- 238000002360 preparation method Methods 0.000 claims 1
- 238000003980 solgel method Methods 0.000 claims 1
- 238000007920 subcutaneous administration Methods 0.000 claims 1
- 230000000699 topical effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FI20135685 | 2013-06-24 | ||
| FI20135685 | 2013-06-24 | ||
| PCT/FI2014/050492 WO2014207304A1 (en) | 2013-06-24 | 2014-06-18 | Silica hydrogel composite |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016522243A JP2016522243A (ja) | 2016-07-28 |
| JP2016522243A5 true JP2016522243A5 (enExample) | 2017-07-20 |
| JP6433490B2 JP6433490B2 (ja) | 2018-12-05 |
Family
ID=51178958
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016520558A Active JP6433490B2 (ja) | 2013-06-24 | 2014-06-18 | シリカハイドロゲルコンポジット |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US9949922B2 (enExample) |
| EP (1) | EP3013317B1 (enExample) |
| JP (1) | JP6433490B2 (enExample) |
| CN (1) | CN105451713B (enExample) |
| AU (1) | AU2014300888B2 (enExample) |
| CA (1) | CA2912483C (enExample) |
| DK (1) | DK3013317T3 (enExample) |
| ES (1) | ES2768606T3 (enExample) |
| HR (1) | HRP20200134T1 (enExample) |
| HU (1) | HUE047897T2 (enExample) |
| LT (1) | LT3013317T (enExample) |
| PL (1) | PL3013317T3 (enExample) |
| PT (1) | PT3013317T (enExample) |
| WO (1) | WO2014207304A1 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USRE48948E1 (en) | 2008-04-18 | 2022-03-01 | Warsaw Orthopedic, Inc. | Clonidine compounds in a biodegradable polymer |
| MX2018004797A (es) | 2015-10-22 | 2018-09-06 | Delsitech Oy | Formulacion de liberacion prolongada a base de un compuesto de hidrogel. |
| FI20155779A7 (fi) * | 2015-10-30 | 2017-05-01 | Solani Therapeutics Ltd | Ei-steroidaalisen anti-inflammatorisen lääkkeen hidastetusti vapautuva annostelu |
| US11772061B2 (en) * | 2016-11-30 | 2023-10-03 | Brown University | Methods of fabricating hyper compliant polymer particles and methods of use and compositions |
| CN111770763A (zh) * | 2018-01-23 | 2020-10-13 | 埃森德生物制药有限公司 | 增强型病毒递送制剂 |
| JP2021531328A (ja) | 2018-06-19 | 2021-11-18 | セラ セラピューティクス エルエルシー | 神経栄養剤、アポトーシスシグナリング断片化阻害剤（ＦＡＳ）もしくはＦＡＳリガンド（ＦＡＳＬ）阻害剤、腫瘍壊死因子α（ＴＮＦ−α）もしくはＴＮＦ受容体阻害剤、ミトコンドリアペプチド、オリゴヌクレオチド、ケモカイン阻害剤、またはシステイン−アスパラギン酸プロテアーゼを含む薬剤送達系 |
| US20210121534A1 (en) | 2018-06-19 | 2021-04-29 | Cella Therapeutics, Llc | Sustained-release drug delivery systems comprising an intraocular pressure lowering agent, a cnp compound, an npr-b compound, a tie-2 agonist, or neurotrophic agent for use for treating glaucoma or ocular hypertension |
| KR20200051916A (ko) * | 2018-11-05 | 2020-05-14 | 주식회사 메디포럼제약 | 고세렐린을 포함하는 실리카 하이드로겔 조성물 |
| EP4009857B1 (en) | 2019-08-06 | 2025-08-20 | DOSE Medical Corporation | Bioerodible cross-linked hydrogel implants and related methods of use |
| CN111443012B (zh) * | 2020-04-09 | 2021-07-20 | 华南理工大学 | 基于复合波等变率温度扫描流变的聚合物凝胶点表征方法 |
| WO2021250626A2 (en) | 2020-06-12 | 2021-12-16 | Glaxosmithkline Biologicals Sa | Dock tag system |
| JP2023532778A (ja) * | 2020-07-07 | 2023-07-31 | デルシテック オサケユイチア | シリカハイドロゲルコンポジットおよびその使用 |
| CN116322778A (zh) * | 2020-10-01 | 2023-06-23 | 斯坦德米洛克斯制药公司 | 水凝胶材料 |
| EP4580600A1 (en) | 2022-09-01 | 2025-07-09 | Optifye Therapeutics AG | Ophthalmic compositions |
| WO2024256756A1 (en) | 2023-06-15 | 2024-12-19 | Delsitech Oy | Injectable composite depot |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CZ297042B6 (cs) * | 1996-05-29 | 2006-08-16 | Delsitechoy | Dodávkové zarízení pro pomalé uvolnování biologicky úcinného cinidla, jeho pouzití a farmaceutický prostredek s jeho obsahem |
| DE10301669A1 (de) * | 2003-01-17 | 2004-07-29 | Gesellschaft zur Förderung von Medizin-, Bio- und Umwelttechnologien e.V. | Bioaktive keramische Kompositmaterialien und Verfahren zu deren Herstellung |
| US10149825B2 (en) | 2004-02-27 | 2018-12-11 | Delsitech Oy | Method for preparing adjustably bioresorbable sol-gel derived SiO2 |
| GB0420016D0 (en) * | 2004-09-09 | 2004-10-13 | Leuven K U Res & Dev | Controlled release oral delivery system |
| EP2023893B1 (en) | 2006-05-23 | 2018-03-14 | DelSiTech Oy | Method for storing silica-based material |
| FI20070174A0 (fi) | 2007-02-28 | 2007-02-28 | Delsitech Oy | Menetelmä silikakoostumusten valmistamiseksi, silikakoostumukset ja niiden käytöt |
| US20090324695A1 (en) | 2008-05-30 | 2009-12-31 | Paul Ducheyne | Biocompatible polymer ceramic composite matrices |
| KR101068873B1 (ko) | 2008-11-28 | 2011-09-30 | 연세대학교 산학협력단 | 바이오마커가 고정된 실리카 나노입자를 함유하는 하이드로젤 및 그 제조방법 |
| US9987225B2 (en) | 2009-09-30 | 2018-06-05 | Ottawa Hospital Research Institute | Crosslinked hydrogels and related method of preparation |
-
2014
- 2014-06-18 HR HRP20200134TT patent/HRP20200134T1/hr unknown
- 2014-06-18 ES ES14739213T patent/ES2768606T3/es active Active
- 2014-06-18 PL PL14739213T patent/PL3013317T3/pl unknown
- 2014-06-18 DK DK14739213.8T patent/DK3013317T3/da active
- 2014-06-18 CA CA2912483A patent/CA2912483C/en active Active
- 2014-06-18 CN CN201480036219.5A patent/CN105451713B/zh active Active
- 2014-06-18 WO PCT/FI2014/050492 patent/WO2014207304A1/en not_active Ceased
- 2014-06-18 JP JP2016520558A patent/JP6433490B2/ja active Active
- 2014-06-18 PT PT147392138T patent/PT3013317T/pt unknown
- 2014-06-18 EP EP14739213.8A patent/EP3013317B1/en active Active
- 2014-06-18 AU AU2014300888A patent/AU2014300888B2/en active Active
- 2014-06-18 US US14/896,612 patent/US9949922B2/en active Active
- 2014-06-18 LT LTEP14739213.8T patent/LT3013317T/lt unknown
- 2014-06-18 HU HUE14739213A patent/HUE047897T2/hu unknown
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