JP2016519649A5 - - Google Patents
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- JP2016519649A5 JP2016519649A5 JP2016500723A JP2016500723A JP2016519649A5 JP 2016519649 A5 JP2016519649 A5 JP 2016519649A5 JP 2016500723 A JP2016500723 A JP 2016500723A JP 2016500723 A JP2016500723 A JP 2016500723A JP 2016519649 A5 JP2016519649 A5 JP 2016519649A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- edible composition
- compound
- composition
- cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims 39
- 108090000765 processed proteins & peptides Proteins 0.000 claims 23
- 150000001875 compounds Chemical class 0.000 claims 22
- 229920001184 polypeptide Polymers 0.000 claims 22
- 102000004196 processed proteins & peptides Human genes 0.000 claims 22
- 238000000034 method Methods 0.000 claims 13
- 241000282324 Felis Species 0.000 claims 11
- 241001465754 Metazoa Species 0.000 claims 9
- 210000004027 cell Anatomy 0.000 claims 8
- 239000000796 flavoring agent Substances 0.000 claims 7
- 235000019634 flavors Nutrition 0.000 claims 7
- 239000000556 agonist Substances 0.000 claims 6
- 239000005557 antagonist Substances 0.000 claims 6
- 239000002157 polynucleotide Substances 0.000 claims 5
- 102000040430 polynucleotide Human genes 0.000 claims 5
- 108091033319 polynucleotide Proteins 0.000 claims 5
- 239000000047 product Substances 0.000 claims 5
- 238000009472 formulation Methods 0.000 claims 4
- 239000002773 nucleotide Substances 0.000 claims 4
- 125000003729 nucleotide group Chemical group 0.000 claims 4
- 241000251468 Actinopterygii Species 0.000 claims 3
- 239000006227 byproduct Substances 0.000 claims 3
- 239000003446 ligand Substances 0.000 claims 3
- 239000000463 material Substances 0.000 claims 3
- 230000001055 chewing effect Effects 0.000 claims 2
- 239000011248 coating agent Substances 0.000 claims 2
- 238000000576 coating method Methods 0.000 claims 2
- 235000013365 dairy product Nutrition 0.000 claims 2
- 235000015872 dietary supplement Nutrition 0.000 claims 2
- 230000035622 drinking Effects 0.000 claims 2
- 239000003623 enhancer Substances 0.000 claims 2
- 239000013604 expression vector Substances 0.000 claims 2
- 235000013305 food Nutrition 0.000 claims 2
- 239000012634 fragment Substances 0.000 claims 2
- 239000003205 fragrance Substances 0.000 claims 2
- 239000000499 gel Substances 0.000 claims 2
- 239000008187 granular material Substances 0.000 claims 2
- 239000007788 liquid Substances 0.000 claims 2
- 239000006072 paste Substances 0.000 claims 2
- 239000000825 pharmaceutical preparation Substances 0.000 claims 2
- 229940127557 pharmaceutical product Drugs 0.000 claims 2
- 239000000843 powder Substances 0.000 claims 2
- 102000004169 proteins and genes Human genes 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 239000005871 repellent Substances 0.000 claims 2
- 230000002940 repellent Effects 0.000 claims 2
- 235000011888 snacks Nutrition 0.000 claims 2
- 239000007787 solid Substances 0.000 claims 2
- 239000007921 spray Substances 0.000 claims 2
- 229940126062 Compound A Drugs 0.000 claims 1
- NLDMNSXOCDLTTB-UHFFFAOYSA-N Heterophylliin A Natural products O1C2COC(=O)C3=CC(O)=C(O)C(O)=C3C3=C(O)C(O)=C(O)C=C3C(=O)OC2C(OC(=O)C=2C=C(O)C(O)=C(O)C=2)C(O)C1OC(=O)C1=CC(O)=C(O)C(O)=C1 NLDMNSXOCDLTTB-UHFFFAOYSA-N 0.000 claims 1
- 241000238631 Hexapoda Species 0.000 claims 1
- 241001529936 Murinae Species 0.000 claims 1
- 230000004913 activation Effects 0.000 claims 1
- 125000003275 alpha amino acid group Chemical group 0.000 claims 1
- 150000001413 amino acids Chemical class 0.000 claims 1
- 238000003556 assay Methods 0.000 claims 1
- 230000001580 bacterial effect Effects 0.000 claims 1
- 210000004899 c-terminal region Anatomy 0.000 claims 1
- 150000001720 carbohydrates Chemical class 0.000 claims 1
- 235000014633 carbohydrates Nutrition 0.000 claims 1
- 230000000295 complement effect Effects 0.000 claims 1
- 230000008021 deposition Effects 0.000 claims 1
- 230000002708 enhancing effect Effects 0.000 claims 1
- 210000005260 human cell Anatomy 0.000 claims 1
- 238000010348 incorporation Methods 0.000 claims 1
- 230000003993 interaction Effects 0.000 claims 1
- 210000004962 mammalian cell Anatomy 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 235000013372 meat Nutrition 0.000 claims 1
- 230000000813 microbial effect Effects 0.000 claims 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 1
- 235000020991 processed meat Nutrition 0.000 claims 1
- 235000013311 vegetables Nutrition 0.000 claims 1
- 210000005253 yeast cell Anatomy 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361788528P | 2013-03-15 | 2013-03-15 | |
| US61/788,528 | 2013-03-15 | ||
| US201461945500P | 2014-02-27 | 2014-02-27 | |
| US61/945,500 | 2014-02-27 | ||
| PCT/US2014/021110 WO2014149829A1 (en) | 2013-03-15 | 2014-03-06 | Feline bitter taste receptors and methods |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016519649A JP2016519649A (ja) | 2016-07-07 |
| JP2016519649A5 true JP2016519649A5 (https=) | 2017-04-06 |
| JP6461901B2 JP6461901B2 (ja) | 2019-01-30 |
Family
ID=50391437
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016500723A Active JP6461901B2 (ja) | 2013-03-15 | 2014-03-06 | ネコ科苦味受容体及び方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US9603379B2 (https=) |
| EP (1) | EP2983507B1 (https=) |
| JP (1) | JP6461901B2 (https=) |
| AU (1) | AU2014237801B2 (https=) |
| BR (1) | BR112015023737A2 (https=) |
| CA (1) | CA2903208C (https=) |
| ES (1) | ES2797547T3 (https=) |
| MX (1) | MX2015013013A (https=) |
| WO (1) | WO2014149829A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9169311B2 (en) | 2013-03-15 | 2015-10-27 | Applied Food Biotechnology, Inc. | Feline bitter taste receptors and methods |
| US11116737B1 (en) | 2020-04-10 | 2021-09-14 | University Of Georgia Research Foundation, Inc. | Methods of using probenecid for treatment of coronavirus infections |
| WO2022224061A1 (en) * | 2021-04-21 | 2022-10-27 | Societe Des Produits Nestle Sa | Methods of identifying modulators of receptors over-expressed in circumvallate taste papillae in animals such as cats, methods of using such modulators in food, and foods made by such methods |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5825980B2 (ja) | 1976-02-12 | 1983-05-31 | ヤマサ醤油株式会社 | サイクリックヌクレオチドの定量法 |
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| US5401629A (en) | 1990-08-07 | 1995-03-28 | The Salk Institute Biotechnology/Industrial Associates, Inc. | Assay methods and compositions useful for measuring the transduction of an intracellular signal |
| EP1214343A2 (en) | 1999-09-10 | 2002-06-19 | The Regents Of The University Of California | T2r taste receptor family |
| US6558910B2 (en) * | 1999-09-10 | 2003-05-06 | The Regents Of The University Of California | SF, a novel family of taste receptors |
| AU5125801A (en) | 2000-04-07 | 2001-10-23 | Senomyx Inc | T2r taste receptors and genes encoding same |
| US7368285B2 (en) | 2001-03-07 | 2008-05-06 | Senomyx, Inc. | Heteromeric umami T1R1/T1R3 taste receptors and isolated cells that express same |
| EP2272957A3 (en) | 2002-09-25 | 2011-08-03 | Deutsches Institut für Ernährungsforschung Potsdam-Rehbrücke | Bitter taste receptors |
| AU2003286069A1 (en) | 2002-12-18 | 2004-07-09 | Givaudan Sa | Chimeric alpha q-gustducin g-proteins |
| DK2311848T3 (da) | 2002-12-23 | 2013-10-14 | Vical Inc | Kodon-optimerede polynukleotidbaserede vacciner mod human cytomegalovirus-infektion |
| WO2004069191A2 (en) | 2003-02-03 | 2004-08-19 | Senomyx Inc. | Identification of t1r and t2r modulators |
| US7579453B2 (en) | 2003-06-19 | 2009-08-25 | The United States Of America As Represented By The Secretary Of The Dapartment Of Health And Human Services | Variants of human taste receptor genes |
| US7527944B2 (en) | 2003-06-27 | 2009-05-05 | Monell Chemical Senses Center | Taste receptors of the T1R family from domestic cat |
| AR046078A1 (es) | 2003-08-06 | 2005-11-23 | Senomyx Inc | Nuevos sabores, modificadores de sabores, sustancias gustativas, mejoradores de gusto, sustancias gustativas y/o mejoradoras del gusto umani o dulce y uso de los mismos. |
| US7541158B2 (en) | 2004-04-14 | 2009-06-02 | Monell Chemical Senses Center | Taste receptors of the T1R family from domestic dog |
| WO2006053771A2 (en) | 2004-11-18 | 2006-05-26 | Deutsches Institut Für Ernährungsforschung Potsdam-Rehbrücke Stiftung Des Öffentlichen Rechts | Agonists of bitter taste receptors and uses thereof |
| JP2008537473A (ja) | 2005-02-08 | 2008-09-18 | セノミクス・インコーポレーテッド | アセトアミノフェン、ラニチジン、ストリキニーネおよびデナトニウムのｐヒトＴ２Ｒ受容体、ならびにヒト苦味調節剤を同定するための関連アッセイ |
| EP1975611A1 (en) | 2007-03-29 | 2008-10-01 | Deutsches Institut für Ernährungsforschung Potsdam -Rehbrücke-Stiftung des öffentlichen Rechts- Vertreten durch den Stiftungsvorstand | Agonists of bitter taste receptors and uses thereof |
| EP2137322B1 (en) | 2007-03-30 | 2013-02-27 | Givaudan SA | Methods to identify tas2r modulators |
| EP1983342A1 (en) | 2007-04-18 | 2008-10-22 | Deutsches Institut für Ernährungsforschung Potsdam -Rehbrücke-Stiftung des öffentlichen Rechts- Vertreten durch den Stiftungsvorstand | Antogonists of bitter taste receptors and uses thereof |
| US7932058B2 (en) | 2007-06-08 | 2011-04-26 | Senomyx, Inc. | Rationale, methods, and assays for identifying human and non-human primate taste specific genes and use thereof in taste modulator and therapeutic screening assays |
| US8546085B2 (en) | 2008-06-13 | 2013-10-01 | Givaudan Sa | Methods of identifying modulators of the bitter taste receptor TAS2R44 |
| EP2924112A1 (en) | 2009-02-02 | 2015-09-30 | Chromocell Corporation | Novel cell lines and methods |
| US8709745B2 (en) * | 2009-07-28 | 2014-04-29 | Deutsches Institut Für Ernährungsforschung Potsdam-Rehbrücke | Methods for isolating ligands of the human bitter taste receptor TAS2R49 |
| US8673578B2 (en) * | 2009-10-27 | 2014-03-18 | Deutsches Institut für Ernahrungsforschung Potsdam-Rehbrücke | Methods of identifying antagonists of the hTAS2R46 bitter taste receptor |
| WO2012013480A1 (en) | 2010-07-27 | 2012-02-02 | Specialites Pet Food | Methods and compositions for stimulating a felidae t1r receptor. |
| US9169311B2 (en) | 2013-03-15 | 2015-10-27 | Applied Food Biotechnology, Inc. | Feline bitter taste receptors and methods |
-
2014
- 2014-03-06 EP EP14714028.9A patent/EP2983507B1/en active Active
- 2014-03-06 BR BR112015023737A patent/BR112015023737A2/pt not_active IP Right Cessation
- 2014-03-06 CA CA2903208A patent/CA2903208C/en active Active
- 2014-03-06 US US14/774,948 patent/US9603379B2/en active Active
- 2014-03-06 WO PCT/US2014/021110 patent/WO2014149829A1/en not_active Ceased
- 2014-03-06 MX MX2015013013A patent/MX2015013013A/es unknown
- 2014-03-06 JP JP2016500723A patent/JP6461901B2/ja active Active
- 2014-03-06 AU AU2014237801A patent/AU2014237801B2/en active Active
- 2014-03-06 ES ES14714028T patent/ES2797547T3/es active Active
-
2017
- 2017-03-27 US US15/469,692 patent/US10174096B2/en active Active
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