AU2014237801B2 - Feline bitter taste receptors and methods - Google Patents
Feline bitter taste receptors and methods Download PDFInfo
- Publication number
- AU2014237801B2 AU2014237801B2 AU2014237801A AU2014237801A AU2014237801B2 AU 2014237801 B2 AU2014237801 B2 AU 2014237801B2 AU 2014237801 A AU2014237801 A AU 2014237801A AU 2014237801 A AU2014237801 A AU 2014237801A AU 2014237801 B2 AU2014237801 B2 AU 2014237801B2
- Authority
- AU
- Australia
- Prior art keywords
- seq
- feline
- polypeptide
- compound
- receptor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/142—Amino acids; Derivatives thereof
- A23K20/147—Polymeric derivatives, e.g. peptides or proteins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K40/00—Shaping or working-up of animal feeding-stuffs
- A23K40/30—Shaping or working-up of animal feeding-stuffs by encapsulating; by coating
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/40—Feeding-stuffs specially adapted for particular animals for carnivorous animals, e.g. cats or dogs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/86—Addition of bitterness inhibitors
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/18—Peptides; Protein hydrolysates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
- G01N33/5041—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects involving analysis of members of signalling pathways
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/02—Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/20—Screening for compounds of potential therapeutic value cell-free systems
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Polymers & Plastics (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Nutrition Science (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Organic Chemistry (AREA)
- Animal Husbandry (AREA)
- Toxicology (AREA)
- Mycology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Birds (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Physiology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361788528P | 2013-03-15 | 2013-03-15 | |
| US61/788,528 | 2013-03-15 | ||
| US201461945500P | 2014-02-27 | 2014-02-27 | |
| US61/945,500 | 2014-02-27 | ||
| PCT/US2014/021110 WO2014149829A1 (en) | 2013-03-15 | 2014-03-06 | Feline bitter taste receptors and methods |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2014237801A1 AU2014237801A1 (en) | 2015-08-27 |
| AU2014237801B2 true AU2014237801B2 (en) | 2017-08-10 |
Family
ID=50391437
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2014237801A Active AU2014237801B2 (en) | 2013-03-15 | 2014-03-06 | Feline bitter taste receptors and methods |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US9603379B2 (https=) |
| EP (1) | EP2983507B1 (https=) |
| JP (1) | JP6461901B2 (https=) |
| AU (1) | AU2014237801B2 (https=) |
| BR (1) | BR112015023737A2 (https=) |
| CA (1) | CA2903208C (https=) |
| ES (1) | ES2797547T3 (https=) |
| MX (1) | MX2015013013A (https=) |
| WO (1) | WO2014149829A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9169311B2 (en) | 2013-03-15 | 2015-10-27 | Applied Food Biotechnology, Inc. | Feline bitter taste receptors and methods |
| US11116737B1 (en) | 2020-04-10 | 2021-09-14 | University Of Georgia Research Foundation, Inc. | Methods of using probenecid for treatment of coronavirus infections |
| WO2022224061A1 (en) * | 2021-04-21 | 2022-10-27 | Societe Des Produits Nestle Sa | Methods of identifying modulators of receptors over-expressed in circumvallate taste papillae in animals such as cats, methods of using such modulators in food, and foods made by such methods |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006053771A2 (en) * | 2004-11-18 | 2006-05-26 | Deutsches Institut Für Ernährungsforschung Potsdam-Rehbrücke Stiftung Des Öffentlichen Rechts | Agonists of bitter taste receptors and uses thereof |
| WO2011012298A1 (en) * | 2009-07-28 | 2011-02-03 | Deutsches Institut Für Ernährungsforschung Potsdam-Rehbrücke | Agonists and antagonists of human bitter taste receptor tas2r49 and uses thereof |
| WO2011050955A1 (en) * | 2009-10-27 | 2011-05-05 | Deutsches Institut Für Ernährungsforschung Potsdam-Rehbrücke | Antagonists and agonists of bitter taste receptors and uses thereof |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5825980B2 (ja) | 1976-02-12 | 1983-05-31 | ヤマサ醤油株式会社 | サイクリックヌクレオチドの定量法 |
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| US5401629A (en) | 1990-08-07 | 1995-03-28 | The Salk Institute Biotechnology/Industrial Associates, Inc. | Assay methods and compositions useful for measuring the transduction of an intracellular signal |
| EP1214343A2 (en) | 1999-09-10 | 2002-06-19 | The Regents Of The University Of California | T2r taste receptor family |
| US6558910B2 (en) * | 1999-09-10 | 2003-05-06 | The Regents Of The University Of California | SF, a novel family of taste receptors |
| AU2001251258B2 (en) | 2000-04-07 | 2008-06-05 | Senomyx, Inc. | T2r taste receptors and genes encoding same |
| US7368285B2 (en) | 2001-03-07 | 2008-05-06 | Senomyx, Inc. | Heteromeric umami T1R1/T1R3 taste receptors and isolated cells that express same |
| EP2267129B1 (en) | 2002-09-25 | 2015-03-25 | Deutsches Institut für Ernährungsforschung Potsdam-Rehbrücke | Bitter taste receptors |
| DE60320682T2 (de) | 2002-12-18 | 2009-06-10 | Givaudan S.A. | Chimäre alpha q-gustducin g-proteine |
| WO2004058166A2 (en) | 2002-12-23 | 2004-07-15 | Vical Incorporated | Codon-optimized polynucleotide-based vaccines against human cytomegalovirus infection |
| WO2004069191A2 (en) | 2003-02-03 | 2004-08-19 | Senomyx Inc. | Identification of t1r and t2r modulators |
| EP1644528A2 (en) | 2003-06-19 | 2006-04-12 | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, the Department of Health and Human Services, | Variants of human taste receptor genes |
| WO2005005480A2 (en) | 2003-06-27 | 2005-01-20 | Monell Chemical Senses Center | Taste receptors of the t1r family from domestic cat |
| BRPI0413347A (pt) | 2003-08-06 | 2006-10-10 | Senomyx Inc | novos sabores, modificadores de sabor, agentes de sabor, realçadores de sabor, agentes de sabor e/ou realçadores umami ou doces, e utilização correspondente |
| EP1753864A2 (en) | 2004-04-14 | 2007-02-21 | Monell Chemical Senses Center | Taste receptors of the t1r family from domestic dog |
| MX2007009497A (es) | 2005-02-08 | 2008-01-18 | Senomyx Inc | Receptores t2r humanos para acetaminofen, ranitidina, estricnina y denatonio, y ensayos relacionados para identificar moduladores de sabor amargo humanos. |
| EP1975611A1 (en) | 2007-03-29 | 2008-10-01 | Deutsches Institut für Ernährungsforschung Potsdam -Rehbrücke-Stiftung des öffentlichen Rechts- Vertreten durch den Stiftungsvorstand | Agonists of bitter taste receptors and uses thereof |
| KR20100016044A (ko) | 2007-03-30 | 2010-02-12 | 지보당 에스아 | 조절제의 동정 방법 |
| EP1983342A1 (en) | 2007-04-18 | 2008-10-22 | Deutsches Institut für Ernährungsforschung Potsdam -Rehbrücke-Stiftung des öffentlichen Rechts- Vertreten durch den Stiftungsvorstand | Antogonists of bitter taste receptors and uses thereof |
| CA2691906A1 (en) | 2007-06-08 | 2009-01-15 | Senomyx, Inc. | Identification of trpml3 (mcoln3) as a salty taste receptor and use in assays for identifying taste (salty) modulators and/or therapeutics that modulate sodium transport, absorption or excretion and/or aldosterone and/or vasopressin production or release |
| WO2009149577A1 (en) | 2008-06-13 | 2009-12-17 | Givaudan Sa | Methods of identifying modulators of the bitter taste receptor tas2r44 |
| KR101751074B1 (ko) | 2009-02-02 | 2017-06-26 | 크로모셀 코포레이션 | 신규한 세포주와 방법 |
| US20130209625A1 (en) | 2010-07-27 | 2013-08-15 | Monell Chemical Senses Center | Methods and compositions for stimulating a felidae t1r receptor |
| US9169311B2 (en) | 2013-03-15 | 2015-10-27 | Applied Food Biotechnology, Inc. | Feline bitter taste receptors and methods |
-
2014
- 2014-03-06 JP JP2016500723A patent/JP6461901B2/ja active Active
- 2014-03-06 ES ES14714028T patent/ES2797547T3/es active Active
- 2014-03-06 MX MX2015013013A patent/MX2015013013A/es unknown
- 2014-03-06 US US14/774,948 patent/US9603379B2/en active Active
- 2014-03-06 WO PCT/US2014/021110 patent/WO2014149829A1/en not_active Ceased
- 2014-03-06 AU AU2014237801A patent/AU2014237801B2/en active Active
- 2014-03-06 BR BR112015023737A patent/BR112015023737A2/pt not_active IP Right Cessation
- 2014-03-06 CA CA2903208A patent/CA2903208C/en active Active
- 2014-03-06 EP EP14714028.9A patent/EP2983507B1/en active Active
-
2017
- 2017-03-27 US US15/469,692 patent/US10174096B2/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006053771A2 (en) * | 2004-11-18 | 2006-05-26 | Deutsches Institut Für Ernährungsforschung Potsdam-Rehbrücke Stiftung Des Öffentlichen Rechts | Agonists of bitter taste receptors and uses thereof |
| WO2011012298A1 (en) * | 2009-07-28 | 2011-02-03 | Deutsches Institut Für Ernährungsforschung Potsdam-Rehbrücke | Agonists and antagonists of human bitter taste receptor tas2r49 and uses thereof |
| WO2011050955A1 (en) * | 2009-10-27 | 2011-05-05 | Deutsches Institut Für Ernährungsforschung Potsdam-Rehbrücke | Antagonists and agonists of bitter taste receptors and uses thereof |
Non-Patent Citations (13)
| Title |
|---|
| - DATABASE e!Ensembl, Database accession no. ENSFCAP00000024300, URL: EBI * |
| - DATABASE REFSEQ, Database accession no. XP_003981606.1 * |
| DATABASE REFSEQ, Database accession no. XP_003982855.1, URL: NCBI * |
| DATABASE REFSEQ, Database accession no. XP_003983168.1, URL: NCBI * |
| DATABASE REFSEQ, Database accession no. XP_003983201.1, URL: NCBI * |
| DATABASE REFSEQ, Database accession no. XP_003983202.1, URL: NCBI * |
| DATABASE REFSEQ, Database accession no. XP_003988464.1, URL: NCBI * |
| DATABASE REFSEQ, Database accession no. XP_003988465.1, URL: NCBI * |
| DATABASE REFSEQ, Database accession no. XP_003988466.1, URL: NCBI * |
| DATABASE REFSEQ, Database accession no. XP_003988469.1, URL: NCBI * |
| DATABASE REFSEQ, Database accession no. XP_003988470.1, URL: NCBI * |
| DATABASE REFSEQ, Database accession no. XP_003988514.1, URL: NCBI * |
| DATABASE REFSEQ, Database accession no. XP_003988515.1, URL: NCBI * |
Also Published As
| Publication number | Publication date |
|---|---|
| JP6461901B2 (ja) | 2019-01-30 |
| JP2016519649A (ja) | 2016-07-07 |
| CA2903208A1 (en) | 2014-09-25 |
| EP2983507B1 (en) | 2020-04-22 |
| US20160015062A1 (en) | 2016-01-21 |
| MX2015013013A (es) | 2015-12-01 |
| US10174096B2 (en) | 2019-01-08 |
| EP2983507A1 (en) | 2016-02-17 |
| ES2797547T3 (es) | 2020-12-02 |
| CA2903208C (en) | 2021-05-18 |
| BR112015023737A2 (pt) | 2017-10-24 |
| US9603379B2 (en) | 2017-03-28 |
| US20170198022A1 (en) | 2017-07-13 |
| AU2014237801A1 (en) | 2015-08-27 |
| WO2014149829A1 (en) | 2014-09-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FGA | Letters patent sealed or granted (standard patent) |