JP2016519105A5 - - Google Patents
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- JP2016519105A5 JP2016519105A5 JP2016507013A JP2016507013A JP2016519105A5 JP 2016519105 A5 JP2016519105 A5 JP 2016519105A5 JP 2016507013 A JP2016507013 A JP 2016507013A JP 2016507013 A JP2016507013 A JP 2016507013A JP 2016519105 A5 JP2016519105 A5 JP 2016519105A5
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- NTQVODZUQIATFS-WAUHAFJUSA-N (2s)-2-[[(2s)-6-amino-2-[[2-[[(2s,3s)-2-[[(2s)-2-[[(2s)-2-amino-3-hydroxypropanoyl]amino]-4-methylpentanoyl]amino]-3-methylpentanoyl]amino]acetyl]amino]hexanoyl]amino]-3-methylbutanoic acid Chemical compound OC[C@H](N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(O)=O NTQVODZUQIATFS-WAUHAFJUSA-N 0.000 claims 1
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13382138.9A EP2792684A1 (en) | 2013-04-15 | 2013-04-15 | Compounds useful in the treatment and/or care of the skin and their cosmetic or pharmaceutical compositions |
| EP13382138.9 | 2013-04-15 | ||
| PCT/EP2014/057672 WO2014170347A1 (en) | 2013-04-15 | 2014-04-15 | Compounds useful in the treatment and/or care of the skin and their cosmetic or pharmaceutical compositions |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016519105A JP2016519105A (ja) | 2016-06-30 |
| JP2016519105A5 true JP2016519105A5 (enExample) | 2019-02-07 |
| JP6525433B2 JP6525433B2 (ja) | 2019-06-05 |
Family
ID=48227117
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016507013A Active JP6525433B2 (ja) | 2013-04-15 | 2014-04-15 | 皮膚の処置および／またはケアにおいて有用な化合物ならびにその美容的または薬学的組成物 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US9458194B2 (enExample) |
| EP (2) | EP2792684A1 (enExample) |
| JP (1) | JP6525433B2 (enExample) |
| KR (1) | KR102260346B1 (enExample) |
| CN (1) | CN105408345B (enExample) |
| AU (1) | AU2014255776B2 (enExample) |
| CA (1) | CA2908863C (enExample) |
| ES (1) | ES2639464T3 (enExample) |
| WO (1) | WO2014170347A1 (enExample) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9486408B2 (en) * | 2005-12-01 | 2016-11-08 | University Of Massachusetts Lowell | Botulinum nanoemulsions |
| US10242871B2 (en) * | 2014-10-21 | 2019-03-26 | Nissan Chemical Industries, Ltd. | Resist underlayer film-forming composition including a compound having an amino group protected with a tert-butoxycarbonyl group |
| KR102481341B1 (ko) | 2014-10-31 | 2022-12-23 | 루브리졸 어드밴스드 머티어리얼스, 인코포레이티드 | 피부 표면으로 활성 작용제의 전달을 위한 열가소성 폴리우레탄 필름 |
| US20180116938A1 (en) * | 2015-04-06 | 2018-05-03 | Lg Household & Health Care Ltd. | Soluble microneedle for delivering proteins or peptides |
| WO2017079248A1 (en) | 2015-11-05 | 2017-05-11 | Lubrizol Advanced Materials, Inc. | Thermoformable dual network hydrogel compositions |
| HK1257429A1 (zh) | 2016-02-04 | 2019-10-18 | ALASTIN Skincare, Inc. | 用於侵入性和非侵入性程序性护肤的组合物和方法 |
| CN106176274B (zh) * | 2016-08-26 | 2020-04-10 | 深圳市维琪医药研发有限公司 | 一种具有抗敏作用的多肽组合物 |
| CN109996532A (zh) * | 2016-10-04 | 2019-07-09 | 玫琳凯有限公司 | 用于处理萎缩纹的方法和组合物 |
| BR102017010169A2 (pt) * | 2017-05-15 | 2019-02-26 | Remer Consultores Assessoria Empresarial Ltda. | composto, intermediário de síntese, uso na preparação de anticonvulsivante, composição farmacêutica anticonvulsivante |
| US11311496B2 (en) | 2016-11-21 | 2022-04-26 | Eirion Therapeutics, Inc. | Transdermal delivery of large agents |
| WO2018101449A1 (ja) * | 2016-11-30 | 2018-06-07 | 株式会社資生堂 | 肌特性解析方法 |
| CA3087881A1 (en) | 2017-01-17 | 2018-07-26 | Michael David FORREST | Therapeutic inhibitors of the reverse mode of atp synthase |
| FR3065876B1 (fr) | 2017-05-05 | 2020-08-14 | Basf Beauty Care Solutions France Sas | Utilisation d'un extrait de nephelium lappaceum pour augmenter la fermete de la peau et/ou des muqueuses |
| US12337000B2 (en) | 2017-07-13 | 2025-06-24 | Michael David FORREST | Therapeutic modulators of the reverse mode of ATP synthase |
| KR102757675B1 (ko) | 2017-08-03 | 2025-01-20 | 앨러스틴 스킨케어, 인크. | 피부 이완 및 신체 윤곽의 개선을 위한 조성물 및 방법 |
| CN108004282B (zh) * | 2017-12-01 | 2021-02-05 | 中国农业科学院麻类研究所 | 一种制备灵芝子实体发酵物的方法、发酵物及其应用 |
| WO2020028694A1 (en) | 2018-08-02 | 2020-02-06 | ALASTIN Skincare, Inc. | Liposomal compositions and methods of use |
| IT201900008364A1 (it) * | 2019-06-07 | 2020-12-07 | Espikem S R L | Peptidi bioattivi e composizioni che li comprendono |
| GB2586577B (en) * | 2019-06-14 | 2024-03-27 | Gelmetix Ltd | Diagnosis and treatment |
| CN111596069B (zh) * | 2020-06-03 | 2021-08-06 | 四川大学华西第二医院 | Hsp10在pop早期预警、诊断、预后评估中的应用和产品 |
| EP4188311A1 (en) * | 2020-07-29 | 2023-06-07 | Karnak Technologies, LLC | Improved formulations of lipophilic subtances for cosmetic uses |
| AU2021358084A1 (en) * | 2020-10-08 | 2023-06-15 | ALASTIN Skincare, Inc. | Compositions and methods relating to stimulation of hyaluronic acid |
| US12223536B2 (en) * | 2020-10-19 | 2025-02-11 | Lillycover Co., Ltd. | Method for providing customized cosmetic product service |
| EP4281034A1 (en) | 2021-01-24 | 2023-11-29 | Forrest, Michael, David | Inhibitors of atp synthase - cosmetic and therapeutic uses |
| CN115670965B (zh) * | 2021-05-17 | 2024-04-19 | 杭州朝与暮品牌管理有限公司 | 一种有效抑制IL-8、TNF-α和IL-6的皮肤抗炎组合物 |
| FR3126309B1 (fr) * | 2021-08-30 | 2024-03-08 | Oreal | COMPOSITION COSMÉTIQUE à BASE DE GLAUCINE, RETINOL ET PEPTIDES POUR COMBATTRE LE VIEILLISSEMENT DE LA PEAU |
| CN113876641A (zh) * | 2021-11-05 | 2022-01-04 | 上海新高姿化妆品有限公司 | 一种具有抗皱紧致功效的化妆品组合物及其应用 |
| CN116120402B (zh) * | 2022-11-04 | 2024-03-15 | 深圳市维琪科技股份有限公司 | 一种环肽及其组合物和用途 |
| CN116440019B (zh) * | 2023-03-27 | 2024-12-27 | 广东馨柯生命科学有限公司 | 含咖啡豆发酵液醒肤咖Supferm COFE和活力咖的防脱生发出水霜及其制备方法 |
| WO2024229256A1 (en) * | 2023-05-03 | 2024-11-07 | Glo Pharma, Inc. | Methods and compositions for cosmetic applications |
| CN117338628B (zh) * | 2023-12-05 | 2024-04-09 | 杭州湃肽生化科技有限公司 | 一种紧肤抗皱组合物及其应用 |
| CN119080885B (zh) * | 2023-12-26 | 2025-09-12 | 杭州湃肽生化科技有限公司 | 环九肽-1及其制备方法及应用 |
| CN119462983B (zh) * | 2024-11-13 | 2025-09-23 | 成都大学 | 一种大枣改性酸性多糖及其制备方法和用途 |
| CN119241661B (zh) * | 2024-11-14 | 2025-08-01 | 云南贝泰妮生物科技集团股份有限公司 | 一种具有抗炎作用的环肽化合物及其制备方法和应用 |
| KR102782681B1 (ko) * | 2024-12-16 | 2025-03-19 | 주식회사 바이오비쥬 | 트로포엘라스틴 가교 활성을 갖는 생체 적합성 폴리머를 포함하는 기능성 조성물 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040126788A1 (en) | 2002-08-13 | 2004-07-01 | Schiemann William P. | Fibulin-5 and uses thereof |
| US7255856B2 (en) | 2004-01-23 | 2007-08-14 | Massachusetts Eye & Ear Infirmary | Lysyl oxidase-like 1 (LOXL1) and elastogenesis |
| WO2008152507A2 (en) | 2007-03-16 | 2008-12-18 | Multigene Vascular Systems, Inc. | Compositions and methods for treating ophthalmic disorders |
| EP2740484A1 (en) * | 2012-12-05 | 2014-06-11 | Lipotec, S.A. | Compounds useful in the treatment and/or care of the skin, hair and/or muccous membranes and their cosmetic or pharmaceutical compositions |
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- 2014-04-15 CA CA2908863A patent/CA2908863C/en active Active
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