JP2016517960A5 - - Google Patents
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- JP2016517960A5 JP2016517960A5 JP2016506682A JP2016506682A JP2016517960A5 JP 2016517960 A5 JP2016517960 A5 JP 2016517960A5 JP 2016506682 A JP2016506682 A JP 2016506682A JP 2016506682 A JP2016506682 A JP 2016506682A JP 2016517960 A5 JP2016517960 A5 JP 2016517960A5
- Authority
- JP
- Japan
- Prior art keywords
- her3
- amount
- her2
- total
- cancer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361809083P | 2013-04-05 | 2013-04-05 | |
| US61/809,083 | 2013-04-05 | ||
| PCT/US2014/033208 WO2014165855A1 (en) | 2013-04-05 | 2014-04-07 | Systems and methods for facilitating diagnosis, prognosis and treatment of cancer based on detection of her3 activation |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016517960A JP2016517960A (ja) | 2016-06-20 |
| JP2016517960A5 true JP2016517960A5 (enExample) | 2017-03-30 |
| JP6402173B2 JP6402173B2 (ja) | 2018-10-10 |
Family
ID=50686216
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016506682A Expired - Fee Related JP6402173B2 (ja) | 2013-04-05 | 2014-04-07 | Her3の検出に基づく癌の診断、予後予測、および処置を容易にするためのシステムおよび方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20160041171A1 (enExample) |
| EP (1) | EP2981828A1 (enExample) |
| JP (1) | JP6402173B2 (enExample) |
| CN (1) | CN105264382A (enExample) |
| CA (1) | CA2908515A1 (enExample) |
| WO (1) | WO2014165855A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3786186A1 (en) | 2014-02-28 | 2021-03-03 | Merus N.V. | Antibodies that bind egfr and erbb3 |
| SMT202500020T1 (it) | 2014-02-28 | 2025-03-12 | Merus Nv | Anticorpo che lega erbb-2 ed erbb-3 |
| WO2016127220A1 (en) * | 2015-02-13 | 2016-08-18 | The University Of Queensland | Methods for classifying tumors and uses therefor |
| WO2017069628A2 (en) | 2015-10-23 | 2017-04-27 | Merus N.V. | Binding molecules that inhibit cancer growth |
| WO2017161030A1 (en) * | 2016-03-15 | 2017-09-21 | Laboratory Corporation Of America Holdings | Methods of assessing protein interactions between cells |
| JP2019519772A (ja) * | 2016-05-31 | 2019-07-11 | ネステク ソシエテ アノニム | Her2及びher3の経路サブタイピングに基づく乳癌患者の薬物療法の選択方法 |
| US11780925B2 (en) | 2017-03-31 | 2023-10-10 | Merus N.V. | ErbB-2 and ErbB3 binding bispecific antibodies for use in the treatment of cells that have an NRG1 fusion gene |
| KR20180117529A (ko) * | 2017-04-19 | 2018-10-29 | 주식회사 프로티나 | 단백질-단백질 상호작용 분석에 의한 약물 반응성 예측 방법 |
| US12195551B2 (en) | 2017-05-17 | 2025-01-14 | Merus N.V. | Combination of an ErbB-2/ErbB-3 bispecific antibody with endocrine therapy for breast cancer |
| SI3665198T1 (sl) | 2017-08-09 | 2025-06-30 | Merus N.V. | Protitelesa, ki vežejo egfr in cmet |
| US20210239702A1 (en) * | 2018-06-14 | 2021-08-05 | Memorial Sloan Kettering Cancer Center | Methods for predicting responsiveness of lung cancer patients to her2-targeting therapies |
Family Cites Families (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4318846A (en) | 1979-09-07 | 1982-03-09 | Syva Company | Novel ether substituted fluorescein polyamino acid compounds as fluorescers and quenchers |
| US4650750A (en) | 1982-02-01 | 1987-03-17 | Giese Roger W | Method of chemical analysis employing molecular release tag compounds |
| US4709016A (en) | 1982-02-01 | 1987-11-24 | Northeastern University | Molecular analytical release tags and their use in chemical analysis |
| US5516931A (en) | 1982-02-01 | 1996-05-14 | Northeastern University | Release tag compounds producing ketone signal groups |
| WO1989006692A1 (en) | 1988-01-12 | 1989-07-27 | Genentech, Inc. | Method of treating tumor cells by inhibiting growth factor receptor function |
| JP2681061B2 (ja) | 1988-06-08 | 1997-11-19 | ロンドン・ダイアグノスティック・インコーポレーテッド | 検出可能なシグナルのセンシタイザー誘導発生を利用したアッセイ |
| US4997928A (en) | 1988-09-15 | 1991-03-05 | E. I. Du Pont De Nemours And Company | Fluorescent reagents for the preparation of 5'-tagged oligonucleotides |
| US5654442A (en) | 1989-11-14 | 1997-08-05 | The Perkin-Elmer Corporation | 4,7-dichlorofluorescein dyes as molecular probes |
| US5183884A (en) | 1989-12-01 | 1993-02-02 | United States Of America | Dna segment encoding a gene for a receptor related to the epidermal growth factor receptor |
| EP0484027B1 (en) | 1990-11-02 | 1996-12-18 | Zeneca Limited | Polysubstituted phthalocyanines |
| JP2758730B2 (ja) | 1991-04-25 | 1998-05-28 | 三菱電機株式会社 | 放電励起パルスレーザ発振装置 |
| US5340716A (en) | 1991-06-20 | 1994-08-23 | Snytex (U.S.A.) Inc. | Assay method utilizing photoactivated chemiluminescent label |
| US5578498A (en) | 1991-05-22 | 1996-11-26 | Behringwerke Ag | Metal chelate containing compositions for use in chemiluminescent assays |
| US6251581B1 (en) | 1991-05-22 | 2001-06-26 | Dade Behring Marburg Gmbh | Assay method utilizing induced luminescence |
| US5565552A (en) | 1992-01-21 | 1996-10-15 | Pharmacyclics, Inc. | Method of expanded porphyrin-oligonucleotide conjugate synthesis |
| US5622929A (en) | 1992-01-23 | 1997-04-22 | Bristol-Myers Squibb Company | Thioether conjugates |
| CA2117913C (en) | 1992-04-10 | 2006-05-09 | Richard J. Epstein | Activation-state-specific phosphoprotein immunodetection |
| ATE162892T1 (de) | 1992-07-31 | 1998-02-15 | Behringwerke Ag | Photoaktivierbare chemiluminizierende matrices |
| US5565324A (en) | 1992-10-01 | 1996-10-15 | The Trustees Of Columbia University In The City Of New York | Complex combinatorial chemical libraries encoded with tags |
| US5811098A (en) | 1992-11-24 | 1998-09-22 | Bristol-Myers Squibb Company | Antibodies to HER4, human receptor tyrosine kinase |
| US5986076A (en) | 1994-05-11 | 1999-11-16 | Trustees Of Boston University | Photocleavable agents and conjugates for the detection and isolation of biomolecules |
| US5968511A (en) | 1996-03-27 | 1999-10-19 | Genentech, Inc. | ErbB3 antibodies |
| US5945526A (en) | 1996-05-03 | 1999-08-31 | Perkin-Elmer Corporation | Energy transfer dyes with enhanced fluorescence |
| US5763602A (en) | 1996-10-01 | 1998-06-09 | Li; Ying-Syi | Methods of syntheses of phthalocyanine compounds |
| US6001673A (en) | 1999-02-11 | 1999-12-14 | Ericsson Inc. | Methods for packaging integrated circuit devices including cavities adjacent active regions |
| US6627400B1 (en) | 1999-04-30 | 2003-09-30 | Aclara Biosciences, Inc. | Multiplexed measurement of membrane protein populations |
| US6673550B2 (en) | 1999-04-30 | 2004-01-06 | Aclara Biosciences, Inc. | Electrophoretic tag reagents comprising fluorescent compounds |
| US6191278B1 (en) | 1999-11-03 | 2001-02-20 | Pe Corporation | Water-soluble rhodamine dyes and conjugates thereof |
| US6372907B1 (en) | 1999-11-03 | 2002-04-16 | Apptera Corporation | Water-soluble rhodamine dye peptide conjugates |
| US6346384B1 (en) | 2000-03-27 | 2002-02-12 | Dade Behring Inc. | Real-time monitoring of PCR using LOCI |
| US20030170734A1 (en) | 2000-04-28 | 2003-09-11 | Stephen Williams | Multiplexed assays using electrophoretically separated molecular tags |
| EP1305632B1 (en) | 2000-05-04 | 2011-07-27 | Siemens Healthcare Diagnostics Products GmbH | Methods for detection of multiple analytes |
| US6547654B2 (en) | 2000-07-22 | 2003-04-15 | Americo Del Raso | Automatic abrasive sleeve tightening means and quick release system for an oscillating spindle sander |
| WO2002095356A2 (en) | 2001-05-21 | 2002-11-28 | Aclara Biosciences, Inc. | Methods and compositions for analyzing proteins |
| EP1283053A1 (en) * | 2001-08-09 | 2003-02-12 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Inhibitors of HER3 activity |
| WO2003051669A1 (en) | 2001-12-18 | 2003-06-26 | Aclara Biosciences, Inc. | Photoactivation device and method |
| WO2003076649A1 (en) | 2002-03-05 | 2003-09-18 | Aclara Biosciences, Inc. | Multiplex analysis using membrane-bound sensitizers |
| US20040229294A1 (en) * | 2002-05-21 | 2004-11-18 | Po-Ying Chan-Hui | ErbB surface receptor complexes as biomarkers |
| US20040229380A1 (en) * | 2002-05-21 | 2004-11-18 | Po-Ying Chan-Hui | ErbB heterodimers as biomarkers |
| HUP0600340A3 (en) * | 2002-07-15 | 2011-06-28 | Genentech Inc | Methods for identifying tumors that are responsive to treatment with anti-erbb2 antibodies |
| JP4443407B2 (ja) * | 2002-07-25 | 2010-03-31 | アクララ バイオサイエンシーズ, インコーポレイテッド | レセプターオリゴマー形成の検出 |
| EP1613732A4 (en) * | 2003-04-01 | 2012-03-14 | Monogram Biosciences Inc | INTRA-CELLULAR COMPLEXES AS BIOMARKERS |
| WO2009068423A2 (en) * | 2007-11-30 | 2009-06-04 | Siemens Healthcare Diagnostics Gmbh | Method for predicting therapy responsiveness in basal like tumors |
| EP2235536A4 (en) | 2007-12-20 | 2011-05-04 | Lab Corp America Holdings | HER-2-DIAGNOSTIC PROCEDURE |
| SG177252A1 (en) | 2008-12-01 | 2012-03-29 | Lab Corp America Holdings | METHODS AND ASSAYS FOR MEASURING p95 AND/OR p95 IN A SAMPLE AND ANTIBODIES SPECIFIC FOR p95 |
| JP2012515353A (ja) | 2009-01-15 | 2012-07-05 | ラボラトリー コーポレイション オブ アメリカ ホールディングス | Her−2発現の測定による患者の反応を判定する方法 |
| SG172983A1 (en) * | 2009-01-15 | 2011-08-29 | Lab Corp America Holdings | Methods of determining patient response by measurement of her-3 |
| WO2013033623A1 (en) * | 2011-09-02 | 2013-03-07 | Nestec S.A. | Profiling of signal pathway proteins to determine therapeutic efficacy |
| CN102492039B (zh) * | 2011-11-21 | 2015-03-11 | 无锡天演生物技术有限公司 | 全人源抗人her2单抗 |
-
2014
- 2014-04-07 CA CA2908515A patent/CA2908515A1/en not_active Abandoned
- 2014-04-07 WO PCT/US2014/033208 patent/WO2014165855A1/en not_active Ceased
- 2014-04-07 JP JP2016506682A patent/JP6402173B2/ja not_active Expired - Fee Related
- 2014-04-07 EP EP14722931.4A patent/EP2981828A1/en not_active Withdrawn
- 2014-04-07 CN CN201480030240.4A patent/CN105264382A/zh active Pending
- 2014-04-07 US US14/781,468 patent/US20160041171A1/en not_active Abandoned
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