JP2016516672A5 - - Google Patents
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- JP2016516672A5 JP2016516672A5 JP2015560373A JP2015560373A JP2016516672A5 JP 2016516672 A5 JP2016516672 A5 JP 2016516672A5 JP 2015560373 A JP2015560373 A JP 2015560373A JP 2015560373 A JP2015560373 A JP 2015560373A JP 2016516672 A5 JP2016516672 A5 JP 2016516672A5
- Authority
- JP
- Japan
- Prior art keywords
- subject
- item
- stem cells
- items
- peripheral blood
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361770533P | 2013-02-28 | 2013-02-28 | |
| US61/770,533 | 2013-02-28 | ||
| US201361828568P | 2013-05-29 | 2013-05-29 | |
| US61/828,568 | 2013-05-29 | ||
| US201361904768P | 2013-11-15 | 2013-11-15 | |
| US61/904,768 | 2013-11-15 | ||
| PCT/US2014/019596 WO2014134539A1 (en) | 2013-02-28 | 2014-02-28 | Methods and compositions for mobilizing stem cells |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020018528A Division JP2020073589A (ja) | 2013-02-28 | 2020-02-06 | 幹細胞を動員するための方法および組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016516672A JP2016516672A (ja) | 2016-06-09 |
| JP2016516672A5 true JP2016516672A5 (https=) | 2017-07-27 |
Family
ID=51428865
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015560373A Withdrawn JP2016516672A (ja) | 2013-02-28 | 2014-02-28 | 幹細胞を動員するための方法および組成物 |
| JP2020018528A Withdrawn JP2020073589A (ja) | 2013-02-28 | 2020-02-06 | 幹細胞を動員するための方法および組成物 |
| JP2021113763A Withdrawn JP2021165306A (ja) | 2013-02-28 | 2021-07-08 | 幹細胞を動員するための方法および組成物 |
| JP2023015363A Pending JP2023041917A (ja) | 2013-02-28 | 2023-02-03 | 幹細胞を動員するための方法および組成物 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020018528A Withdrawn JP2020073589A (ja) | 2013-02-28 | 2020-02-06 | 幹細胞を動員するための方法および組成物 |
| JP2021113763A Withdrawn JP2021165306A (ja) | 2013-02-28 | 2021-07-08 | 幹細胞を動員するための方法および組成物 |
| JP2023015363A Pending JP2023041917A (ja) | 2013-02-28 | 2023-02-03 | 幹細胞を動員するための方法および組成物 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US11116819B2 (https=) |
| EP (2) | EP2961828A4 (https=) |
| JP (4) | JP2016516672A (https=) |
| KR (3) | KR20230050355A (https=) |
| CN (2) | CN105431521A (https=) |
| AU (3) | AU2014224042B2 (https=) |
| CA (1) | CA2908227A1 (https=) |
| SG (2) | SG10201706858XA (https=) |
| WO (1) | WO2014134539A1 (https=) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108498532B (zh) | 2012-05-09 | 2021-07-23 | 坎泰克斯制药股份有限公司 | 骨髓抑制的治疗 |
| JP2016516672A (ja) | 2013-02-28 | 2016-06-09 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 幹細胞を動員するための方法および組成物 |
| CN106470676A (zh) * | 2014-05-08 | 2017-03-01 | 德克萨斯大学系统董事会 | 用于非细胞毒性干细胞移植的方法和组合物 |
| US10052346B2 (en) | 2015-02-17 | 2018-08-21 | Cantex Pharmaceuticals, Inc. | Treatment of myelodysplastic syndromes with 2-O and,or 3-O desulfated heparinoids |
| US20160243168A1 (en) * | 2015-02-17 | 2016-08-25 | Cantex Pharmaceuticals, Inc. | Adoptive cell transfer methods |
| HK1249534A1 (zh) | 2015-04-06 | 2018-11-02 | 哈佛大学校长及研究员协会 | 用於非清髓性预处理的组合物和方法 |
| CA3026154A1 (en) | 2015-06-03 | 2016-12-08 | The University Of Queensland | Mobilizing agents and uses therefor |
| JP2019507596A (ja) * | 2016-02-26 | 2019-03-22 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 生着性の高い造血幹細胞 |
| CN109641051A (zh) | 2016-06-17 | 2019-04-16 | 美真达治疗公司 | 用于耗尽细胞的组合物和方法 |
| CN106086075B (zh) * | 2016-06-23 | 2019-08-06 | 福建医科大学 | CXCR4RNAi慢病毒载体的构建方法 |
| EP3526260A4 (en) * | 2016-10-13 | 2020-11-18 | President and Fellows of Harvard College | NON-MYELOABLATIVE PACKAGING COMPOSITIONS AND METHODS |
| MX395639B (es) | 2017-01-20 | 2025-03-25 | Heidelberg Pharma Res Gmbh | Composiciones y métodos para el agotamiento de células cd137+. |
| WO2018182612A1 (en) * | 2017-03-30 | 2018-10-04 | Progenity Inc. | Methods and ingestible devices for the regio-specific release of stem cells at the site of gastrointestinal tract disease |
| CN108728393B (zh) * | 2017-04-24 | 2020-05-26 | 中国科学院上海营养与健康研究所 | Vcam-1+单核细胞及其衍生细胞在促进造血干细胞归巢的应用 |
| CN107711615B (zh) * | 2017-10-31 | 2020-08-11 | 金华职业技术学院 | 一种采用浸泡鱼卵获得不育鱼的方法 |
| EP3704232A1 (en) * | 2017-10-31 | 2020-09-09 | Magenta Therapeutics, Inc. | Compositions and methods for the expansion of hematopoietic stem and progenitor cells |
| WO2019089833A1 (en) * | 2017-10-31 | 2019-05-09 | Magenta Therapeutics Inc. | Compositions and methods for hematopoietic stem and progenitor cell transplant therapy |
| EP3703714A1 (en) * | 2017-11-03 | 2020-09-09 | Roemer & Heigl GmbH | Extraction of stem cells from bone marrow niches |
| WO2019108863A1 (en) | 2017-11-29 | 2019-06-06 | Magenta Therapeutics, Inc. | Compositions and methods for the depletion of cd5+ cells |
| CN111712262A (zh) * | 2017-12-06 | 2020-09-25 | 美真达治疗公司 | 用于动员造血干细胞和祖细胞的给药方案 |
| US10058573B1 (en) | 2017-12-06 | 2018-08-28 | Magenta Therapeutics, Inc. | Dosing regimens for the mobilization of hematopoietic stem cells |
| US11260079B2 (en) | 2017-12-06 | 2022-03-01 | Magenta Therapeutics, Inc. | Dosing regimens for the mobilization of hematopoietic stem and progenitor cells |
| US20210162009A1 (en) * | 2017-12-08 | 2021-06-03 | The Medical College Of Wisconsin, Inc. | Chemokine variants as immune stimulants |
| EP3735412B1 (en) * | 2018-01-03 | 2024-02-21 | EdiGene Biotechnology, Inc. | Compositions and methods for the expansion of hematopoietic stem and progenitor cells and treatment of inherited metabolic disorders |
| WO2019199984A1 (en) * | 2018-04-13 | 2019-10-17 | The Regents Of The University Of California | Methods for treating sickle cell disease |
| US12559720B2 (en) | 2018-08-30 | 2026-02-24 | The Regents Of The University Of California | Mobilization and collection of peripheral blood hematopoietic stem cells and lymphocytes from deceased donors |
| US11495028B2 (en) * | 2018-09-28 | 2022-11-08 | Intel Corporation | Obstacle analyzer, vehicle control system, and methods thereof |
| KR102142956B1 (ko) * | 2018-11-09 | 2020-08-10 | 코아스템(주) | 중간엽줄기세포의 증식 및 이동 능력 예측용 바이오마커 및 이의 용도 |
| CN109731002B (zh) * | 2019-03-21 | 2020-02-11 | 广州沙艾生物科技有限公司 | 白酒草皂苷r用于制备造血干细胞动员剂的应用 |
| US20220401481A1 (en) * | 2019-11-01 | 2022-12-22 | Magenta Therapeutics, Inc. | Dosing regimens for the mobilization of hematopoietic stem and progenitor cells |
| WO2021138447A1 (en) | 2019-12-31 | 2021-07-08 | Elixirgen Therapeutics, Inc. | Temperature-based transient delivery of nucleic acids and proteins to cells and tissues |
| MX2022007910A (es) * | 2019-12-31 | 2022-08-25 | Elixirgen Therapeutics Inc | Distribucion transitoria basada en temperatura de ácidos nucleicos y proteínas de zscan4 a células y tejidos. |
| US12188049B2 (en) * | 2020-04-14 | 2025-01-07 | Tzu Chi University | Methods for mobilizing stem cells |
| KR102398968B1 (ko) * | 2020-07-13 | 2022-05-17 | (주) 엘피스셀테라퓨틱스 | 조혈 줄기세포의 가동을 위한 물질-p의 배합 요법 |
| CO2020015994A1 (es) | 2020-12-18 | 2022-06-21 | Inst Distrital De Ciencia Biotecnologia E Innovacion En Salud Idcbis | Método in vitro para evaluación funcional de progenitores hematopoyéticos |
| CN116024172B (zh) * | 2021-10-27 | 2025-06-03 | 复旦大学 | 一种阳离子化合物在制备造血干细胞或祖细胞动员剂中的应用 |
| AU2022400940A1 (en) * | 2021-11-30 | 2024-06-13 | Ohio State Innovation Foundation | Engineered cells and uses thereof |
| WO2023133595A2 (en) | 2022-01-10 | 2023-07-13 | Sana Biotechnology, Inc. | Methods of ex vivo dosing and administration of lipid particles or viral vectors and related systems and uses |
| WO2024081820A1 (en) | 2022-10-13 | 2024-04-18 | Sana Biotechnology, Inc. | Viral particles targeting hematopoietic stem cells |
| WO2024119157A1 (en) | 2022-12-02 | 2024-06-06 | Sana Biotechnology, Inc. | Lipid particles with cofusogens and methods of producing and using the same |
| KR20260016952A (ko) | 2023-05-23 | 2026-02-04 | 사나 바이오테크놀로지, 인크. | 탠덤 퓨소젠 및 관련 지질 입자 |
| CN116920069B (zh) * | 2023-07-06 | 2024-05-17 | 廊坊康宝汇泰生物技术有限公司 | 一种中药提取液及其在促进脐带干细胞分泌vegf中的应用 |
| JPWO2025170079A1 (https=) * | 2024-02-09 | 2025-08-14 | ||
| WO2025184529A1 (en) | 2024-03-01 | 2025-09-04 | Sana Biotechnology, Inc. | Viral particles with fusogen display and related compositions and methods |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH07118160B2 (ja) | 1983-06-18 | 1995-12-18 | ソニー株式会社 | ディジタル情報信号の記録方法 |
| DE3422518A1 (de) | 1984-06-16 | 1985-12-19 | B. Braun Melsungen Ag, 3508 Melsungen | Heparin-derivate, verfahren zu ihrer herstellung, diese enthaltende arzneimittel und ihre verwendung bei der behandlung von fettstoffwechselstoerungen |
| US6753463B1 (en) | 1987-11-18 | 2004-06-22 | Mycogen Corporation | Transformed cotton plants |
| DE3744119A1 (de) | 1987-12-24 | 1989-07-06 | Basf Ag | Verwendung von polysulfatierten heparinen |
| US5596090A (en) | 1992-07-24 | 1997-01-21 | The United States Of America As Represented By The Secretary Of The Navy | Antisense oligonucleotides directed against human VCAM-1 RNA |
| DE69433301T2 (de) | 1993-06-08 | 2004-09-09 | Smithkline Beecham Corp. | Methoden zur erhöhung der biologischen aktivität von chemokinen |
| US6042821A (en) | 1995-11-21 | 2000-03-28 | Smithkline Beecham Corporation | Method of treating sepsis with chemokines |
| DE19549232C2 (de) | 1995-12-20 | 1998-05-20 | Boehringer Mannheim Gmbh | Verwendung von G-CSF in Kombination mit einem Chemotherapeutikum bei der Behandlung von Erkrankungen, die eine periphere Stammzelltransplantation erfordern |
| IL164568A0 (en) | 1997-05-14 | 2005-12-18 | Atherogenics Inc | Compounds and methods for the inhibition of the expression of vcam-1 |
| JP2003528109A (ja) | 2000-03-21 | 2003-09-24 | アセロジエニクス・インコーポレイテツド | Vcam−1の発現を阻害するためのチオケタール及びチオエーテル |
| JP4855253B2 (ja) | 2003-07-29 | 2012-01-18 | ドムペ・ファ.ル.マ・ソチエタ・ペル・アツィオーニ | 幹細胞動員に有用な医薬の組み合わせ |
| KR100533978B1 (ko) * | 2004-06-30 | 2005-12-07 | 주식회사 하이닉스반도체 | 반도체 소자 제조 방법 |
| JP2008509928A (ja) * | 2004-08-13 | 2008-04-03 | アノーメド インコーポレイテッド | 前駆/幹細胞を動員するためのケモカインの組み合わせ |
| US7790174B2 (en) | 2004-12-23 | 2010-09-07 | Merck Serono Sa | G-CSF polypeptides and uses thereof |
| JP2010507567A (ja) * | 2006-08-07 | 2010-03-11 | ジェンザイム・コーポレーション | 併用療法 |
| ES2882360T3 (es) * | 2006-11-03 | 2021-12-01 | Univ Leland Stanford Junior | Inmunoempobrecimiento selectivo de un nicho de células madre endógenas para injerto |
| US8383124B2 (en) | 2008-03-12 | 2013-02-26 | Children's Hospital Medical Center | Mobilization of hematopoietic stem cells |
| WO2010022017A2 (en) | 2008-08-19 | 2010-02-25 | Hartmut Geiger | Method and composition for enhancing hematopoietic stem cell mobilization |
| EP2356128A1 (en) * | 2008-09-15 | 2011-08-17 | Endotis Pharma | Oligosaccharide compounds for use in mobilising stem cells |
| PT3031907T (pt) | 2008-11-06 | 2021-01-28 | Univ Indiana Res & Tech Corp | Materiais e métodos para melhorar procedimentos de enxerto de células estaminais hematopoiéticas |
| US8642569B2 (en) * | 2009-01-21 | 2014-02-04 | The General Hospital Corporation | Methods for expansion of hematopoietic stem and progenitor cells |
| WO2011030847A1 (ja) | 2009-09-10 | 2011-03-17 | 国立大学法人京都大学 | 造血幹細胞誘導剤組成物 |
| WO2012106367A2 (en) * | 2011-01-31 | 2012-08-09 | Royal Daniel F | Pluripotent stem cells and method of stimulating and extracting non-embryonic pluripotent stem cells from mammal blood and using reconstituted pluripotent stem cells to treat diseases including chronic obstructive pulmonary disease |
| US20120225028A1 (en) | 2011-03-02 | 2012-09-06 | Moshe Cohen | Compositions and methods for mobilization of stem cells |
| JP2016516672A (ja) | 2013-02-28 | 2016-06-09 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 幹細胞を動員するための方法および組成物 |
-
2014
- 2014-02-28 JP JP2015560373A patent/JP2016516672A/ja not_active Withdrawn
- 2014-02-28 WO PCT/US2014/019596 patent/WO2014134539A1/en not_active Ceased
- 2014-02-28 KR KR1020237006132A patent/KR20230050355A/ko not_active Ceased
- 2014-02-28 EP EP14756575.8A patent/EP2961828A4/en not_active Withdrawn
- 2014-02-28 CN CN201480023643.6A patent/CN105431521A/zh active Pending
- 2014-02-28 CA CA2908227A patent/CA2908227A1/en not_active Abandoned
- 2014-02-28 SG SG10201706858XA patent/SG10201706858XA/en unknown
- 2014-02-28 KR KR1020217035065A patent/KR102503695B1/ko active Active
- 2014-02-28 US US14/771,280 patent/US11116819B2/en not_active Expired - Fee Related
- 2014-02-28 SG SG11201508027PA patent/SG11201508027PA/en unknown
- 2014-02-28 EP EP22197478.5A patent/EP4169533A1/en not_active Withdrawn
- 2014-02-28 CN CN202110729258.5A patent/CN113616779A/zh active Pending
- 2014-02-28 KR KR1020157027014A patent/KR20160023638A/ko not_active Ceased
- 2014-02-28 AU AU2014224042A patent/AU2014224042B2/en not_active Ceased
-
2020
- 2020-02-06 JP JP2020018528A patent/JP2020073589A/ja not_active Withdrawn
- 2020-03-27 AU AU2020202179A patent/AU2020202179A1/en not_active Abandoned
- 2020-04-15 US US16/849,950 patent/US20200268850A1/en not_active Abandoned
-
2021
- 2021-07-08 JP JP2021113763A patent/JP2021165306A/ja not_active Withdrawn
-
2022
- 2022-06-16 AU AU2022204193A patent/AU2022204193A1/en not_active Abandoned
-
2023
- 2023-02-03 JP JP2023015363A patent/JP2023041917A/ja active Pending
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