JP2016516672A5 - - Google Patents

Download PDF

Info

Publication number
JP2016516672A5
JP2016516672A5 JP2015560373A JP2015560373A JP2016516672A5 JP 2016516672 A5 JP2016516672 A5 JP 2016516672A5 JP 2015560373 A JP2015560373 A JP 2015560373A JP 2015560373 A JP2015560373 A JP 2015560373A JP 2016516672 A5 JP2016516672 A5 JP 2016516672A5
Authority
JP
Japan
Prior art keywords
subject
item
stem cells
items
peripheral blood
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2015560373A
Other languages
English (en)
Japanese (ja)
Other versions
JP2016516672A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2014/019596 external-priority patent/WO2014134539A1/en
Publication of JP2016516672A publication Critical patent/JP2016516672A/ja
Publication of JP2016516672A5 publication Critical patent/JP2016516672A5/ja
Withdrawn legal-status Critical Current

Links

JP2015560373A 2013-02-28 2014-02-28 幹細胞を動員するための方法および組成物 Withdrawn JP2016516672A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201361770533P 2013-02-28 2013-02-28
US61/770,533 2013-02-28
US201361828568P 2013-05-29 2013-05-29
US61/828,568 2013-05-29
US201361904768P 2013-11-15 2013-11-15
US61/904,768 2013-11-15
PCT/US2014/019596 WO2014134539A1 (en) 2013-02-28 2014-02-28 Methods and compositions for mobilizing stem cells

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2020018528A Division JP2020073589A (ja) 2013-02-28 2020-02-06 幹細胞を動員するための方法および組成物

Publications (2)

Publication Number Publication Date
JP2016516672A JP2016516672A (ja) 2016-06-09
JP2016516672A5 true JP2016516672A5 (https=) 2017-07-27

Family

ID=51428865

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2015560373A Withdrawn JP2016516672A (ja) 2013-02-28 2014-02-28 幹細胞を動員するための方法および組成物
JP2020018528A Withdrawn JP2020073589A (ja) 2013-02-28 2020-02-06 幹細胞を動員するための方法および組成物
JP2021113763A Withdrawn JP2021165306A (ja) 2013-02-28 2021-07-08 幹細胞を動員するための方法および組成物
JP2023015363A Pending JP2023041917A (ja) 2013-02-28 2023-02-03 幹細胞を動員するための方法および組成物

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2020018528A Withdrawn JP2020073589A (ja) 2013-02-28 2020-02-06 幹細胞を動員するための方法および組成物
JP2021113763A Withdrawn JP2021165306A (ja) 2013-02-28 2021-07-08 幹細胞を動員するための方法および組成物
JP2023015363A Pending JP2023041917A (ja) 2013-02-28 2023-02-03 幹細胞を動員するための方法および組成物

Country Status (9)

Country Link
US (2) US11116819B2 (https=)
EP (2) EP2961828A4 (https=)
JP (4) JP2016516672A (https=)
KR (3) KR20230050355A (https=)
CN (2) CN105431521A (https=)
AU (3) AU2014224042B2 (https=)
CA (1) CA2908227A1 (https=)
SG (2) SG10201706858XA (https=)
WO (1) WO2014134539A1 (https=)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108498532B (zh) 2012-05-09 2021-07-23 坎泰克斯制药股份有限公司 骨髓抑制的治疗
JP2016516672A (ja) 2013-02-28 2016-06-09 プレジデント アンド フェローズ オブ ハーバード カレッジ 幹細胞を動員するための方法および組成物
CN106470676A (zh) * 2014-05-08 2017-03-01 德克萨斯大学系统董事会 用于非细胞毒性干细胞移植的方法和组合物
US10052346B2 (en) 2015-02-17 2018-08-21 Cantex Pharmaceuticals, Inc. Treatment of myelodysplastic syndromes with 2-O and,or 3-O desulfated heparinoids
US20160243168A1 (en) * 2015-02-17 2016-08-25 Cantex Pharmaceuticals, Inc. Adoptive cell transfer methods
HK1249534A1 (zh) 2015-04-06 2018-11-02 哈佛大学校长及研究员协会 用於非清髓性预处理的组合物和方法
CA3026154A1 (en) 2015-06-03 2016-12-08 The University Of Queensland Mobilizing agents and uses therefor
JP2019507596A (ja) * 2016-02-26 2019-03-22 プレジデント アンド フェローズ オブ ハーバード カレッジ 生着性の高い造血幹細胞
CN109641051A (zh) 2016-06-17 2019-04-16 美真达治疗公司 用于耗尽细胞的组合物和方法
CN106086075B (zh) * 2016-06-23 2019-08-06 福建医科大学 CXCR4RNAi慢病毒载体的构建方法
EP3526260A4 (en) * 2016-10-13 2020-11-18 President and Fellows of Harvard College NON-MYELOABLATIVE PACKAGING COMPOSITIONS AND METHODS
MX395639B (es) 2017-01-20 2025-03-25 Heidelberg Pharma Res Gmbh Composiciones y métodos para el agotamiento de células cd137+.
WO2018182612A1 (en) * 2017-03-30 2018-10-04 Progenity Inc. Methods and ingestible devices for the regio-specific release of stem cells at the site of gastrointestinal tract disease
CN108728393B (zh) * 2017-04-24 2020-05-26 中国科学院上海营养与健康研究所 Vcam-1+单核细胞及其衍生细胞在促进造血干细胞归巢的应用
CN107711615B (zh) * 2017-10-31 2020-08-11 金华职业技术学院 一种采用浸泡鱼卵获得不育鱼的方法
EP3704232A1 (en) * 2017-10-31 2020-09-09 Magenta Therapeutics, Inc. Compositions and methods for the expansion of hematopoietic stem and progenitor cells
WO2019089833A1 (en) * 2017-10-31 2019-05-09 Magenta Therapeutics Inc. Compositions and methods for hematopoietic stem and progenitor cell transplant therapy
EP3703714A1 (en) * 2017-11-03 2020-09-09 Roemer & Heigl GmbH Extraction of stem cells from bone marrow niches
WO2019108863A1 (en) 2017-11-29 2019-06-06 Magenta Therapeutics, Inc. Compositions and methods for the depletion of cd5+ cells
CN111712262A (zh) * 2017-12-06 2020-09-25 美真达治疗公司 用于动员造血干细胞和祖细胞的给药方案
US10058573B1 (en) 2017-12-06 2018-08-28 Magenta Therapeutics, Inc. Dosing regimens for the mobilization of hematopoietic stem cells
US11260079B2 (en) 2017-12-06 2022-03-01 Magenta Therapeutics, Inc. Dosing regimens for the mobilization of hematopoietic stem and progenitor cells
US20210162009A1 (en) * 2017-12-08 2021-06-03 The Medical College Of Wisconsin, Inc. Chemokine variants as immune stimulants
EP3735412B1 (en) * 2018-01-03 2024-02-21 EdiGene Biotechnology, Inc. Compositions and methods for the expansion of hematopoietic stem and progenitor cells and treatment of inherited metabolic disorders
WO2019199984A1 (en) * 2018-04-13 2019-10-17 The Regents Of The University Of California Methods for treating sickle cell disease
US12559720B2 (en) 2018-08-30 2026-02-24 The Regents Of The University Of California Mobilization and collection of peripheral blood hematopoietic stem cells and lymphocytes from deceased donors
US11495028B2 (en) * 2018-09-28 2022-11-08 Intel Corporation Obstacle analyzer, vehicle control system, and methods thereof
KR102142956B1 (ko) * 2018-11-09 2020-08-10 코아스템(주) 중간엽줄기세포의 증식 및 이동 능력 예측용 바이오마커 및 이의 용도
CN109731002B (zh) * 2019-03-21 2020-02-11 广州沙艾生物科技有限公司 白酒草皂苷r用于制备造血干细胞动员剂的应用
US20220401481A1 (en) * 2019-11-01 2022-12-22 Magenta Therapeutics, Inc. Dosing regimens for the mobilization of hematopoietic stem and progenitor cells
WO2021138447A1 (en) 2019-12-31 2021-07-08 Elixirgen Therapeutics, Inc. Temperature-based transient delivery of nucleic acids and proteins to cells and tissues
MX2022007910A (es) * 2019-12-31 2022-08-25 Elixirgen Therapeutics Inc Distribucion transitoria basada en temperatura de ácidos nucleicos y proteínas de zscan4 a células y tejidos.
US12188049B2 (en) * 2020-04-14 2025-01-07 Tzu Chi University Methods for mobilizing stem cells
KR102398968B1 (ko) * 2020-07-13 2022-05-17 (주) 엘피스셀테라퓨틱스 조혈 줄기세포의 가동을 위한 물질-p의 배합 요법
CO2020015994A1 (es) 2020-12-18 2022-06-21 Inst Distrital De Ciencia Biotecnologia E Innovacion En Salud Idcbis Método in vitro para evaluación funcional de progenitores hematopoyéticos
CN116024172B (zh) * 2021-10-27 2025-06-03 复旦大学 一种阳离子化合物在制备造血干细胞或祖细胞动员剂中的应用
AU2022400940A1 (en) * 2021-11-30 2024-06-13 Ohio State Innovation Foundation Engineered cells and uses thereof
WO2023133595A2 (en) 2022-01-10 2023-07-13 Sana Biotechnology, Inc. Methods of ex vivo dosing and administration of lipid particles or viral vectors and related systems and uses
WO2024081820A1 (en) 2022-10-13 2024-04-18 Sana Biotechnology, Inc. Viral particles targeting hematopoietic stem cells
WO2024119157A1 (en) 2022-12-02 2024-06-06 Sana Biotechnology, Inc. Lipid particles with cofusogens and methods of producing and using the same
KR20260016952A (ko) 2023-05-23 2026-02-04 사나 바이오테크놀로지, 인크. 탠덤 퓨소젠 및 관련 지질 입자
CN116920069B (zh) * 2023-07-06 2024-05-17 廊坊康宝汇泰生物技术有限公司 一种中药提取液及其在促进脐带干细胞分泌vegf中的应用
JPWO2025170079A1 (https=) * 2024-02-09 2025-08-14
WO2025184529A1 (en) 2024-03-01 2025-09-04 Sana Biotechnology, Inc. Viral particles with fusogen display and related compositions and methods

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07118160B2 (ja) 1983-06-18 1995-12-18 ソニー株式会社 ディジタル情報信号の記録方法
DE3422518A1 (de) 1984-06-16 1985-12-19 B. Braun Melsungen Ag, 3508 Melsungen Heparin-derivate, verfahren zu ihrer herstellung, diese enthaltende arzneimittel und ihre verwendung bei der behandlung von fettstoffwechselstoerungen
US6753463B1 (en) 1987-11-18 2004-06-22 Mycogen Corporation Transformed cotton plants
DE3744119A1 (de) 1987-12-24 1989-07-06 Basf Ag Verwendung von polysulfatierten heparinen
US5596090A (en) 1992-07-24 1997-01-21 The United States Of America As Represented By The Secretary Of The Navy Antisense oligonucleotides directed against human VCAM-1 RNA
DE69433301T2 (de) 1993-06-08 2004-09-09 Smithkline Beecham Corp. Methoden zur erhöhung der biologischen aktivität von chemokinen
US6042821A (en) 1995-11-21 2000-03-28 Smithkline Beecham Corporation Method of treating sepsis with chemokines
DE19549232C2 (de) 1995-12-20 1998-05-20 Boehringer Mannheim Gmbh Verwendung von G-CSF in Kombination mit einem Chemotherapeutikum bei der Behandlung von Erkrankungen, die eine periphere Stammzelltransplantation erfordern
IL164568A0 (en) 1997-05-14 2005-12-18 Atherogenics Inc Compounds and methods for the inhibition of the expression of vcam-1
JP2003528109A (ja) 2000-03-21 2003-09-24 アセロジエニクス・インコーポレイテツド Vcam−1の発現を阻害するためのチオケタール及びチオエーテル
JP4855253B2 (ja) 2003-07-29 2012-01-18 ドムペ・ファ.ル.マ・ソチエタ・ペル・アツィオーニ 幹細胞動員に有用な医薬の組み合わせ
KR100533978B1 (ko) * 2004-06-30 2005-12-07 주식회사 하이닉스반도체 반도체 소자 제조 방법
JP2008509928A (ja) * 2004-08-13 2008-04-03 アノーメド インコーポレイテッド 前駆/幹細胞を動員するためのケモカインの組み合わせ
US7790174B2 (en) 2004-12-23 2010-09-07 Merck Serono Sa G-CSF polypeptides and uses thereof
JP2010507567A (ja) * 2006-08-07 2010-03-11 ジェンザイム・コーポレーション 併用療法
ES2882360T3 (es) * 2006-11-03 2021-12-01 Univ Leland Stanford Junior Inmunoempobrecimiento selectivo de un nicho de células madre endógenas para injerto
US8383124B2 (en) 2008-03-12 2013-02-26 Children's Hospital Medical Center Mobilization of hematopoietic stem cells
WO2010022017A2 (en) 2008-08-19 2010-02-25 Hartmut Geiger Method and composition for enhancing hematopoietic stem cell mobilization
EP2356128A1 (en) * 2008-09-15 2011-08-17 Endotis Pharma Oligosaccharide compounds for use in mobilising stem cells
PT3031907T (pt) 2008-11-06 2021-01-28 Univ Indiana Res & Tech Corp Materiais e métodos para melhorar procedimentos de enxerto de células estaminais hematopoiéticas
US8642569B2 (en) * 2009-01-21 2014-02-04 The General Hospital Corporation Methods for expansion of hematopoietic stem and progenitor cells
WO2011030847A1 (ja) 2009-09-10 2011-03-17 国立大学法人京都大学 造血幹細胞誘導剤組成物
WO2012106367A2 (en) * 2011-01-31 2012-08-09 Royal Daniel F Pluripotent stem cells and method of stimulating and extracting non-embryonic pluripotent stem cells from mammal blood and using reconstituted pluripotent stem cells to treat diseases including chronic obstructive pulmonary disease
US20120225028A1 (en) 2011-03-02 2012-09-06 Moshe Cohen Compositions and methods for mobilization of stem cells
JP2016516672A (ja) 2013-02-28 2016-06-09 プレジデント アンド フェローズ オブ ハーバード カレッジ 幹細胞を動員するための方法および組成物

Similar Documents

Publication Publication Date Title
JP2016516672A5 (https=)
JP2021165306A (ja) 幹細胞を動員するための方法および組成物
Suratt et al. Human pulmonary chimerism after hematopoietic stem cell transplantation
Pusic et al. Update on clinical experience with AMD3100, an SDF-1/CXCL12–CXCR4 inhibitor, in mobilization of hematopoietic stem and progenitor cells
Peled et al. The high-affinity CXCR4 antagonist BKT140 is safe and induces a robust mobilization of human CD34+ cells in patients with multiple myeloma
Rocha et al. New approaches for improving engraftment after cord blood transplantation
Voermans et al. In vitro migratory capacity of CD34+ cells is related to hematopoietic recovery after autologous stem cell transplantation
Goligorsky et al. Dysfunctional endothelial progenitor cells in chronic kidney disease
Tsolaki et al. Hematopoietic stem cells and liver regeneration: differentially acting hematopoietic stem cell mobilization agents reverse induced chronic liver injury
Sangidorj et al. Bone marrow-derived endothelial progenitor cells confer renal protection in a murine chronic renal failure model
Andreone et al. Reinfusion of highly purified CD133+ bone marrow-derived stem/progenitor cells in patients with end-stage liver disease: A phase I clinical trial
Wang et al. EPC infusion ameliorates acute graft-versus-host disease-related endothelial injury after allogeneic bone marrow transplantation
Hildebrandt et al. Donor T-cell production of RANTES significantly contributes to the development of idiopathic pneumonia syndrome after allogeneic stem cell transplantation
Fadini Is bone marrow another target of diabetic complications?
Falkenham et al. Early fibroblast progenitor cell migration to the AngII-exposed myocardium is not CXCL12 or CCL2 dependent as previously thought
Metheny et al. Posttransplant intramuscular injection of PLX-R18 mesenchymal-like adherent stromal cells improves human hematopoietic engraftment in a murine transplant model
De Vries et al. The happy destiny of frozen haematopoietic stem cells: from immature stem cells to mature applications
Davy et al. Hematopoietic stem cells are a critical sub-population of whole bone marrow in the treatment of myocardial infarction
Cannon Iii et al. BM-derived cell therapies for cardiovascular disease
Beksac et al. Leland Metheny1*, Saada Eid2, 3, Karen Lingas2, 3, Racheli Ofir4, Lena Pinzur4, Howard Meyerson5, 6, Hillard M. Lazarus1 and Alex Y. Huang2, 3, 5, 6
Dams-Kozlowska et al. Effects of designer hyper-interleukin 11 (H11) on hematopoiesis in myelosuppressed mice
Greco et al. 253: Diminished Biological Potency of BM-Derived CD133+ Cells Obtained from Patients with Coronary Artery Disease in in vitro and in vivo Studies
Ramirez et al. 252: Mobilization of Murine HSCs with AMD15057, A Small Molecule Inhibitor of CD49d (VLA4)
CA2624138A1 (en) Method and composition for increasing the engraftment efficiency of stem cells
Olavarria Autografting in Chronic Myeloid Leukemia