JP2016516058A5 - - Google Patents
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- Publication number
- JP2016516058A5 JP2016516058A5 JP2016503061A JP2016503061A JP2016516058A5 JP 2016516058 A5 JP2016516058 A5 JP 2016516058A5 JP 2016503061 A JP2016503061 A JP 2016503061A JP 2016503061 A JP2016503061 A JP 2016503061A JP 2016516058 A5 JP2016516058 A5 JP 2016516058A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- seleno
- adenosyl
- composition according
- selenium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 8
- 239000000203 mixture Substances 0.000 claims 4
- 239000011669 selenium Substances 0.000 claims 4
- 210000004027 cell Anatomy 0.000 claims 3
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 claims 2
- 150000001875 compounds Chemical class 0.000 claims 2
- 229910052711 selenium Inorganic materials 0.000 claims 2
- FNOAUVDPFTXXAL-WOUKDFQISA-N (2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-5-ethyl-2-(hydroxymethyl)-4-selanyloxolan-3-ol Chemical compound C1=NC2=C(N)N=CN=C2N1[C@]1(CC)O[C@H](CO)[C@@H](O)[C@H]1[SeH] FNOAUVDPFTXXAL-WOUKDFQISA-N 0.000 claims 1
- 239000004475 Arginine Substances 0.000 claims 1
- AHKPTFGAKUWJCR-XDTOVJCPSA-N CC([C@@H]1[C@H]([C@H]([C@@H](O1)N1C=NC=2C(N)=NC=NC12)[SeH])O)O Chemical compound CC([C@@H]1[C@H]([C@H]([C@@H](O1)N1C=NC=2C(N)=NC=NC12)[SeH])O)O AHKPTFGAKUWJCR-XDTOVJCPSA-N 0.000 claims 1
- RNVXFUXWIQAZEI-UHFFFAOYSA-N C[Se]=O Chemical compound C[Se]=O RNVXFUXWIQAZEI-UHFFFAOYSA-N 0.000 claims 1
- DLMSNSCUXVJFII-WOYAITHZSA-N OC(=O)[C@@H](N)CC[SeH].CC(=O)N[C@@H](CS)C(O)=O Chemical compound OC(=O)[C@@H](N)CC[SeH].CC(=O)N[C@@H](CS)C(O)=O DLMSNSCUXVJFII-WOYAITHZSA-N 0.000 claims 1
- ZJUKTBDSGOFHSH-WFMPWKQPSA-N S-Adenosylhomocysteine Chemical compound O[C@@H]1[C@H](O)[C@@H](CSCC[C@H](N)C(O)=O)O[C@H]1N1C2=NC=NC(N)=C2N=C1 ZJUKTBDSGOFHSH-WFMPWKQPSA-N 0.000 claims 1
- XDSSPSLGNGIIHP-VKHMYHEASA-N Se-methyl-L-selenocysteine Chemical compound C[Se]C[C@H]([NH3+])C([O-])=O XDSSPSLGNGIIHP-VKHMYHEASA-N 0.000 claims 1
- MVYBVFNWZFFZLH-BXXYBDJJSA-N [C@@H]1([C@H](O)C[C@@H](CO)O1)N1C=NC=2C(N)=NC=NC12.OC=1[Se]C=CC1 Chemical compound [C@@H]1([C@H](O)C[C@@H](CO)O1)N1C=NC=2C(N)=NC=NC12.OC=1[Se]C=CC1 MVYBVFNWZFFZLH-BXXYBDJJSA-N 0.000 claims 1
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 claims 1
- 239000008298 dragée Substances 0.000 claims 1
- 229950003188 isovaleryl diethylamide Drugs 0.000 claims 1
- 125000001909 leucine group Chemical group [H]N(*)C(C(*)=O)C([H])([H])C(C([H])([H])[H])C([H])([H])[H] 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 1
- 210000003470 mitochondria Anatomy 0.000 claims 1
- 230000004898 mitochondrial function Effects 0.000 claims 1
- 239000006187 pill Substances 0.000 claims 1
- 239000000843 powder Substances 0.000 claims 1
- 239000007940 sugar coated tablet Substances 0.000 claims 1
- 239000000725 suspension Substances 0.000 claims 1
- 239000006188 syrup Substances 0.000 claims 1
- 235000020357 syrup Nutrition 0.000 claims 1
- 239000003826 tablet Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361788133P | 2013-03-15 | 2013-03-15 | |
| US61/788,133 | 2013-03-15 | ||
| PCT/US2014/029328 WO2014144776A1 (en) | 2013-03-15 | 2014-03-14 | Compositions comprising selenium and use of same for the treatment and prevention of disease or conditions associated with mitochondrial dysfunction |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016516058A JP2016516058A (ja) | 2016-06-02 |
| JP2016516058A5 true JP2016516058A5 (OSRAM) | 2017-04-06 |
| JP6313418B2 JP6313418B2 (ja) | 2018-04-18 |
Family
ID=51537786
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016503061A Active JP6313418B2 (ja) | 2013-03-15 | 2014-03-14 | セレンを含む組成物、並びにミトコンドリア機能不全と関連する疾患または状態の処置および予防のためのその使用 |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US9833486B2 (OSRAM) |
| EP (1) | EP2968404A4 (OSRAM) |
| JP (1) | JP6313418B2 (OSRAM) |
| KR (1) | KR102245702B1 (OSRAM) |
| CN (3) | CN105377271A (OSRAM) |
| AU (1) | AU2014228785B2 (OSRAM) |
| BR (1) | BR112015022514A2 (OSRAM) |
| CA (1) | CA2903845C (OSRAM) |
| CL (1) | CL2015002677A1 (OSRAM) |
| HK (1) | HK1216506A1 (OSRAM) |
| MX (1) | MX359626B (OSRAM) |
| RU (1) | RU2663127C2 (OSRAM) |
| SG (2) | SG10202101918RA (OSRAM) |
| WO (1) | WO2014144776A1 (OSRAM) |
| ZA (1) | ZA201506759B (OSRAM) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112015022936A2 (pt) | 2013-03-14 | 2017-07-18 | J Schentag Jerome | vesículas de colestossoma para a incorporação de moléculas em quilomícrons |
| CA2940283C (en) * | 2014-03-14 | 2021-03-30 | Alltech, Inc. | Compositions of selenoorganic compounds and methods of use thereof |
| WO2016160594A1 (en) | 2015-03-27 | 2016-10-06 | The Research Foundation For The State University Of New York | Methods and materials for reducing amyloid beta levels within a mammal |
| WO2017048252A1 (en) * | 2015-09-15 | 2017-03-23 | Alltech, Inc. | Compositions of selenoorganic compounds and methods of use thereof |
| AU2017234662A1 (en) * | 2016-03-14 | 2018-10-04 | Mitogenetics, Llc | Materials and methods for treating hypoxic conditions |
| CN120647702A (zh) | 2017-05-19 | 2025-09-16 | 全技术公司 | 药剂、组合物及其相关方法 |
| CA3188049A1 (en) * | 2018-04-25 | 2019-10-31 | Oncocross Co.,Ltd. | Composition for preventing and treating muscular disease |
| CN108283711A (zh) * | 2018-05-06 | 2018-07-17 | 冷立娟 | 一种治疗酒精性心肌病的中药冲剂及其制备方法 |
| CN109820933A (zh) * | 2019-02-27 | 2019-05-31 | 北京曲佳科技有限公司 | 减肥片及其制备方法 |
| CN111493325A (zh) * | 2020-05-07 | 2020-08-07 | 恩施德源健康科技发展有限公司 | 植物硒肽在制备改善肥胖及代谢综合征组合物中的应用 |
| KR20230029674A (ko) * | 2020-06-29 | 2023-03-03 | 브리스톨-마이어스 스큅 컴퍼니 | 생물반응기로부터의 샘플을 분석하기 위한 자동화 시스템 및 방법 |
| CN112129864B (zh) * | 2020-09-24 | 2022-04-01 | 江南大学 | 一种富硒植物干粉中硒形态测定的方法 |
| KR102328808B1 (ko) * | 2020-12-02 | 2021-11-22 | 동의대학교 산학협력단 | 맥주효모를 이용한 근감소증 예방 및 개선용 조성물 |
| CN114053298A (zh) * | 2021-11-19 | 2022-02-18 | 华中农业大学 | 一种用于抑制心肌肥大的药物及模型的构建方法 |
| CN114235989A (zh) * | 2021-11-27 | 2022-03-25 | 山东省烟台市农业科学研究院 | 一种测定福美甲胂含量的高效液相色谱法 |
| CN114031650B (zh) * | 2021-11-29 | 2023-05-02 | 上海交通大学 | 壳寡糖硒配位化合物及其制备方法和应用 |
| CN114924001B (zh) * | 2022-05-12 | 2024-11-19 | 中国计量科学研究院 | 一种基于独立校准的含磷或含硒化合物标准溶液定值方法 |
| CN114931569B (zh) * | 2022-06-22 | 2023-05-16 | 中国农业科学院油料作物研究所 | 甲基硒代半胱氨酸在制备提高雄性生殖能力的产品中的应用 |
| CN116333302B (zh) * | 2023-03-31 | 2024-09-10 | 中南大学 | 一种稳定持久抗氧化纳米点及其在二型糖尿病中的应用 |
| CN116421618B (zh) * | 2023-06-15 | 2023-09-29 | 暨南大学 | Se@NADH的制备方法及其在脊髓损伤治疗中的应用 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5896024A (ja) * | 1981-10-16 | 1983-06-07 | リチヤ−ド・エフ・ストツケル | 白金毒解毒剤 |
| WO2004107881A1 (en) * | 2003-06-04 | 2004-12-16 | Serfontein, Willem, Jacob | Nutritional compositions and use thereof |
| PL214402B1 (pl) * | 2003-08-11 | 2013-07-31 | Tomasz Byrski | Zastosowanie selenu albo jego zwiazku do otrzymywania srodka do obnizania odziedziczonego ryzyka zachorowania na raka piersi lub jajnika |
| US20070026090A1 (en) * | 2003-09-05 | 2007-02-01 | Oren Tirosh | Treatment and prevention of inflammatory disease and mitochondrial dysfunction with high dose selenium |
| US8871715B2 (en) * | 2005-10-14 | 2014-10-28 | Alltech, Inc. | Use of selenium compounds, especially selenium yeasts for altering cognitive function |
| CN101073584B (zh) * | 2005-10-14 | 2012-10-10 | 全面技术公司 | 改变细胞功能的方法和组合物 |
| US20100247679A1 (en) | 2006-04-24 | 2010-09-30 | Alltech, Inc. | Methods and compositions for altering cell function |
| CA2724833C (en) * | 2007-05-18 | 2015-11-24 | Alltech, Inc. | Use of seleneium yeast composition for establishing and/or maintaining pregnancy |
| AU2008283794B2 (en) | 2007-07-31 | 2014-03-20 | Board Of Regents, The University Of Texas System | Micro-RNAs that control myosin expression and myofiber identity |
| WO2009032057A2 (en) * | 2007-08-29 | 2009-03-12 | Adam Lubin | Method for the selective therapy of disease |
| BRPI0818007A2 (pt) * | 2007-10-16 | 2015-11-03 | Exichol Sa | composição para regular o metabolismo lipídico |
| CN101579355B (zh) * | 2009-05-27 | 2010-12-08 | 徐建兴 | 一种维护线粒体功能的营养组合物及其应用 |
| PE20121709A1 (es) * | 2009-10-22 | 2012-12-17 | Propanc Pty Ltd | Una composicion farmaceutica para tratar cancer que comprende tripsinogeno y/o quimotripsinogeno y un agente activo seleccionado a partir de un compuesto de selenio, un compuesto vainilloide y un agente reductor de glicolisis citoplasmica |
| WO2011132799A1 (en) * | 2010-04-22 | 2011-10-27 | Kyoto University | Method for inducing differentiation of pluripotent stem cells into skeletal muscle or skeletal muscle progenitor cells |
| KR20120048205A (ko) * | 2010-11-05 | 2012-05-15 | 한국식품연구원 | 메틸셀레노시스테인을 유효성분으로 함유하는 비만 및 지질 관련 대사성 질환의 예방 및 치료용 조성물 |
| KR102100091B1 (ko) * | 2011-04-13 | 2020-04-14 | 아지노모토 가부시키가이샤 | 영양 조성물 |
-
2014
- 2014-03-14 RU RU2015139742A patent/RU2663127C2/ru active
- 2014-03-14 SG SG10202101918RA patent/SG10202101918RA/en unknown
- 2014-03-14 US US14/776,307 patent/US9833486B2/en active Active
- 2014-03-14 HK HK16104529.4A patent/HK1216506A1/zh unknown
- 2014-03-14 EP EP14762675.8A patent/EP2968404A4/en active Pending
- 2014-03-14 CN CN201480028372.3A patent/CN105377271A/zh active Pending
- 2014-03-14 AU AU2014228785A patent/AU2014228785B2/en active Active
- 2014-03-14 CN CN202210024252.2A patent/CN114533753A/zh active Pending
- 2014-03-14 SG SG11201507061XA patent/SG11201507061XA/en unknown
- 2014-03-14 KR KR1020157029100A patent/KR102245702B1/ko active Active
- 2014-03-14 MX MX2015013275A patent/MX359626B/es active IP Right Grant
- 2014-03-14 CA CA2903845A patent/CA2903845C/en active Active
- 2014-03-14 BR BR112015022514A patent/BR112015022514A2/pt not_active Application Discontinuation
- 2014-03-14 CN CN202210387608.9A patent/CN114984038A/zh active Pending
- 2014-03-14 WO PCT/US2014/029328 patent/WO2014144776A1/en not_active Ceased
- 2014-03-14 JP JP2016503061A patent/JP6313418B2/ja active Active
-
2015
- 2015-09-11 ZA ZA2015/06759A patent/ZA201506759B/en unknown
- 2015-09-14 CL CL2015002677A patent/CL2015002677A1/es unknown
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