JP2016513642A5 - - Google Patents
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- JP2016513642A5 JP2016513642A5 JP2016500713A JP2016500713A JP2016513642A5 JP 2016513642 A5 JP2016513642 A5 JP 2016513642A5 JP 2016500713 A JP2016500713 A JP 2016500713A JP 2016500713 A JP2016500713 A JP 2016500713A JP 2016513642 A5 JP2016513642 A5 JP 2016513642A5
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- Prior art keywords
- amino
- pharmaceutical composition
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- item
- compound
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- 150000001875 compounds Chemical class 0.000 claims description 30
- 239000008194 pharmaceutical composition Substances 0.000 claims description 21
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 claims description 16
- 238000000034 method Methods 0.000 claims description 14
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims description 14
- -1 2-amino-5-chloro-4-thiazolyl Chemical group 0.000 claims description 12
- 239000000203 mixture Substances 0.000 claims description 9
- 239000004471 Glycine Substances 0.000 claims description 8
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims description 8
- 229930006000 Sucrose Natural products 0.000 claims description 8
- 239000005720 sucrose Substances 0.000 claims description 8
- 239000012458 free base Substances 0.000 claims description 6
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 claims description 6
- 208000035143 Bacterial infection Diseases 0.000 claims description 4
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims description 4
- 208000022362 bacterial infectious disease Diseases 0.000 claims description 4
- 230000015556 catabolic process Effects 0.000 claims description 4
- 238000006731 degradation reaction Methods 0.000 claims description 4
- 239000003937 drug carrier Substances 0.000 claims description 4
- 238000004519 manufacturing process Methods 0.000 claims description 4
- 239000003814 drug Substances 0.000 claims description 2
- 150000003839 salts Chemical class 0.000 claims description 2
- 238000002560 therapeutic procedure Methods 0.000 claims description 2
- 238000004128 high performance liquid chromatography Methods 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361779065P | 2013-03-13 | 2013-03-13 | |
| US61/779,065 | 2013-03-13 | ||
| PCT/US2014/021064 WO2014158952A1 (en) | 2013-03-13 | 2014-03-06 | Hydrochloride salts of an antibiotic compound |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017028372A Division JP2017082016A (ja) | 2013-03-13 | 2017-02-17 | 抗生物質化合物の塩酸塩 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016513642A JP2016513642A (ja) | 2016-05-16 |
| JP2016513642A5 true JP2016513642A5 (cg-RX-API-DMAC7.html) | 2017-03-30 |
| JP6482523B2 JP6482523B2 (ja) | 2019-03-13 |
Family
ID=50483481
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016500713A Active JP6482523B2 (ja) | 2013-03-13 | 2014-03-06 | 抗生物質化合物の塩酸塩 |
| JP2017028372A Withdrawn JP2017082016A (ja) | 2013-03-13 | 2017-02-17 | 抗生物質化合物の塩酸塩 |
| JP2018153560A Withdrawn JP2018177817A (ja) | 2013-03-13 | 2018-08-17 | 抗生物質化合物の塩酸塩 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017028372A Withdrawn JP2017082016A (ja) | 2013-03-13 | 2017-02-17 | 抗生物質化合物の塩酸塩 |
| JP2018153560A Withdrawn JP2018177817A (ja) | 2013-03-13 | 2018-08-17 | 抗生物質化合物の塩酸塩 |
Country Status (32)
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016154100A1 (en) * | 2015-03-24 | 2016-09-29 | Elevance Renewable Sciences, Inc. | Polyol esters of metathesized fatty acids and uses thereof |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4434287A (en) * | 1975-02-20 | 1984-02-28 | Ciba-Geigy Corporation | Cephalosporin derivatives |
| AR228726A1 (es) | 1978-05-26 | 1983-04-15 | Glaxo Group Ltd | Procedimiento para la preparacion del antibiotico(6r,7r)-7-((z)-2-(2-aminotiazol-4-il)-2-(2-carboxiprop-2-oxiimino)acetamido)-3-(1-piridiniometil)cef-3-em-4-carboxilato |
| US4626534A (en) | 1984-07-23 | 1986-12-02 | Eli Lilly And Company | Pharmaceutical formulation |
| DE3801179A1 (de) | 1988-01-18 | 1989-07-27 | Hoechst Ag | Stabilisierung von cephalosporinderivaten durch trocknung mit einem stabilisator sowie stabile zubereitungsformen mit cephalosporinderivaten |
| JPH0331449A (ja) | 1989-06-27 | 1991-02-12 | Yamaha Corp | リードフレーム用Ｆｅ―Ｎｉ合金 |
| EP0421297B1 (en) | 1989-09-30 | 1993-12-01 | Eisai Co., Ltd. | Injectable preparations containing cephalosporin medicament and the use thereof |
| JPH03193735A (ja) | 1989-12-22 | 1991-08-23 | Shionogi & Co Ltd | グリコペプチド系抗生物質の安定化組成物 |
| JP4142149B2 (ja) | 1997-07-10 | 2008-08-27 | 明治製菓株式会社 | バンコマイシンの凍結乾燥製剤 |
| TWI335332B (en) * | 2001-10-12 | 2011-01-01 | Theravance Inc | Cross-linked vancomycin-cephalosporin antibiotics |
| DE602004028111D1 (de) * | 2003-04-16 | 2010-08-26 | Sandoz Ag | Verfahren zur herstellung von cefepim |
| JP2007500222A (ja) | 2003-05-23 | 2007-01-11 | セラヴァンス インコーポレーテッド | 架橋グリコペプチド−セファロスポリン抗生物質 |
| US6878868B2 (en) | 2003-06-24 | 2005-04-12 | Mcmillan Stacy L. | Portable high-hat device |
| WO2005005436A2 (en) | 2003-07-11 | 2005-01-20 | Theravance, Inc. | Cross-linked glycopeptide-cephalosporin antibiotics |
| TWI342312B (en) | 2003-10-22 | 2011-05-21 | Theravance Inc | Hydrochloride salts of a glycopeptide phosphonate derivative |
| EP1656930A1 (en) | 2004-11-10 | 2006-05-17 | Basilea Pharmaceutica AG | Stabilized freeze-dried formulation for cephalosporin derivatives |
| US20080103121A1 (en) | 2006-10-30 | 2008-05-01 | Gole Dilip J | Cephalosporin derivative formulation |
| FR2932177B1 (fr) | 2008-06-06 | 2012-11-30 | Inst Francais Du Petrole | Procede d'hydrogenation selective sur un catalyseur contenant de l'or. |
| JP2010105965A (ja) | 2008-10-30 | 2010-05-13 | Taiyo Yakuhin Kogyo Kk | バンコマイシン製剤 |
| WO2011035108A1 (en) | 2009-09-17 | 2011-03-24 | Eagle Pharmaceuticals, Inc. | Formulations of daptomycin |
| EP2504020A4 (en) | 2009-11-23 | 2013-05-29 | Eagle Pharmaceuticals Inc | Daptomycin FORMULATIONS |
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2014
- 2014-03-06 DK DK14717248.0T patent/DK2968446T3/en active
- 2014-03-06 US US14/198,956 patent/US9161990B2/en active Active
- 2014-03-06 AU AU2014241481A patent/AU2014241481B9/en not_active Ceased
- 2014-03-06 SG SG11201507235YA patent/SG11201507235YA/en unknown
- 2014-03-06 MD MDA20150101A patent/MD4599C1/ro active IP Right Grant
- 2014-03-06 WO PCT/US2014/021064 patent/WO2014158952A1/en not_active Ceased
- 2014-03-06 PL PL14717248T patent/PL2968446T3/pl unknown
- 2014-03-06 GE GEAP201413957A patent/GEP20186874B/en unknown
- 2014-03-06 ME MEP-2017-133A patent/ME02854B/me unknown
- 2014-03-06 LT LTEP14717248.0T patent/LT2968446T/lt unknown
- 2014-03-06 HR HRP20171188TT patent/HRP20171188T1/hr unknown
- 2014-03-06 HU HUE14717248A patent/HUE033738T2/hu unknown
- 2014-03-06 CN CN201480013969.0A patent/CN105120883B/zh active Active
- 2014-03-06 MX MX2015012170A patent/MX361984B/es active IP Right Grant
- 2014-03-06 CA CA2902720A patent/CA2902720A1/en not_active Abandoned
- 2014-03-06 UA UAA201509921A patent/UA115086C2/uk unknown
- 2014-03-06 PT PT147172480T patent/PT2968446T/pt unknown
- 2014-03-06 BR BR112015022716A patent/BR112015022716A2/pt not_active Application Discontinuation
- 2014-03-06 EP EP14717248.0A patent/EP2968446B1/en active Active
- 2014-03-06 EA EA201591697A patent/EA027282B1/ru unknown
- 2014-03-06 RS RS20170621A patent/RS56141B1/sr unknown
- 2014-03-06 SI SI201430302T patent/SI2968446T1/sl unknown
- 2014-03-06 KR KR1020157027597A patent/KR20150126659A/ko not_active Withdrawn
- 2014-03-06 SM SM20170369T patent/SMT201700369T1/it unknown
- 2014-03-06 TW TW103107730A patent/TWI608845B/zh not_active IP Right Cessation
- 2014-03-06 ES ES14717248.0T patent/ES2633964T3/es active Active
- 2014-03-06 JP JP2016500713A patent/JP6482523B2/ja active Active
- 2014-03-07 AR ARP140100742A patent/AR095044A1/es unknown
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2015
- 2015-08-18 IL IL240663A patent/IL240663A0/en not_active IP Right Cessation
- 2015-09-11 ZA ZA2015/06748A patent/ZA201506748B/en unknown
- 2015-09-11 PH PH12015502060A patent/PH12015502060A1/en unknown
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2017
- 2017-02-17 JP JP2017028372A patent/JP2017082016A/ja not_active Withdrawn
- 2017-07-28 CY CY20171100810T patent/CY1119316T1/el unknown
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2018
- 2018-08-17 JP JP2018153560A patent/JP2018177817A/ja not_active Withdrawn