JP2016513098A - 癌の標的治療用抗体と抱合した極めて強力なプロドラック形態の２−ピロリノドキソルビシン（ｐ２ｐｄｏｘ） - Google Patents

癌の標的治療用抗体と抱合した極めて強力なプロドラック形態の２−ピロリノドキソルビシン（ｐ２ｐｄｏｘ） Download PDF

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JP2016513098A
JP2016513098A JP2015557088A JP2015557088A JP2016513098A JP 2016513098 A JP2016513098 A JP 2016513098A JP 2015557088 A JP2015557088 A JP 2015557088A JP 2015557088 A JP2015557088 A JP 2015557088A JP 2016513098 A JP2016513098 A JP 2016513098A
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antibody
cancer
p2pdox
antigen
complex
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JP2016513098A5 (fr
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ゴヴィンダン，セレンガラム，ブイ．
ジェー． マクブライド，ウィリアム
ジェー． マクブライド，ウィリアム
サティアナラヤン，ナリーニ
マッザ−フェレイラ，クリスティーヌ
エム． ゴールデンバーグ，デイビッド
エム． ゴールデンバーグ，デイビッド
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Immunomedics Inc
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Immunomedics Inc
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3007—Carcino-embryonic Antigens
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JP2015557088A 2013-02-07 2014-02-07 癌の標的治療用抗体と抱合した極めて強力なプロドラック形態の２−ピロリノドキソルビシン（ｐ２ｐｄｏｘ） Pending JP2016513098A (ja)

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PCT/US2014/015253 WO2014124227A1 (fr) 2013-02-07 2014-02-07 Forme de pro-médicament (p2pdox) de la 2-pyrrolinodoxorubicine fortement puissante conjuguée à des anticorps pour la thérapie ciblée du cancer

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US9095628B2 (en) 2015-08-04
US8877202B2 (en) 2014-11-04
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