JP2016512602A5 - - Google Patents
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- JP2016512602A5 JP2016512602A5 JP2015558133A JP2015558133A JP2016512602A5 JP 2016512602 A5 JP2016512602 A5 JP 2016512602A5 JP 2015558133 A JP2015558133 A JP 2015558133A JP 2015558133 A JP2015558133 A JP 2015558133A JP 2016512602 A5 JP2016512602 A5 JP 2016512602A5
- Authority
- JP
- Japan
- Prior art keywords
- peptide mixture
- distinct
- mass
- peptides
- peptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 108090000765 processed proteins & peptides Proteins 0.000 claims description 109
- 239000000203 mixture Substances 0.000 claims description 54
- 238000004949 mass spectrometry Methods 0.000 claims description 40
- 238000004811 liquid chromatography Methods 0.000 claims description 39
- 102000004196 processed proteins & peptides Human genes 0.000 claims description 38
- 238000000034 method Methods 0.000 claims description 32
- 230000035945 sensitivity Effects 0.000 claims description 10
- 150000001413 amino acids Chemical class 0.000 claims description 6
- 238000012442 analytical experiment Methods 0.000 claims description 4
- 239000002131 composite material Substances 0.000 claims description 4
- 230000014759 maintenance of location Effects 0.000 claims description 4
- 230000003595 spectral effect Effects 0.000 claims description 4
- 239000012535 impurity Substances 0.000 claims description 2
- 238000003491 array Methods 0.000 claims 1
- 238000001514 detection method Methods 0.000 description 6
- JCLFHZLOKITRCE-UHFFFAOYSA-N 4-pentoxyphenol Chemical compound CCCCCOC1=CC=C(O)C=C1 JCLFHZLOKITRCE-UHFFFAOYSA-N 0.000 description 3
- 238000002955 isolation Methods 0.000 description 3
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 2
- 238000011156 evaluation Methods 0.000 description 2
- 102000004142 Trypsin Human genes 0.000 description 1
- 108090000631 Trypsin Proteins 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 238000004445 quantitative analysis Methods 0.000 description 1
- 239000012898 sample dilution Substances 0.000 description 1
- 239000012588 trypsin Substances 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361764312P | 2013-02-13 | 2013-02-13 | |
| US61/764,312 | 2013-02-13 | ||
| PCT/US2014/016289 WO2014127144A2 (en) | 2013-02-13 | 2014-02-13 | Quality control reagents and methods |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018159973A Division JP6563574B2 (ja) | 2013-02-13 | 2018-08-29 | 品質管理試薬及び方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016512602A JP2016512602A (ja) | 2016-04-28 |
| JP2016512602A5 true JP2016512602A5 (enExample) | 2017-03-16 |
| JP6396337B2 JP6396337B2 (ja) | 2018-09-26 |
Family
ID=51350143
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015558133A Active JP6396337B2 (ja) | 2013-02-13 | 2014-02-13 | 品質管理試薬及び方法 |
| JP2018159973A Active JP6563574B2 (ja) | 2013-02-13 | 2018-08-29 | 品質管理試薬及び方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018159973A Active JP6563574B2 (ja) | 2013-02-13 | 2018-08-29 | 品質管理試薬及び方法 |
Country Status (4)
| Country | Link |
|---|---|
| US (4) | US10247711B2 (enExample) |
| EP (2) | EP4290231A3 (enExample) |
| JP (2) | JP6396337B2 (enExample) |
| WO (1) | WO2014127144A2 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006096704A2 (en) | 2005-03-07 | 2006-09-14 | Invitrogen Corporation | Isotopically-labeled proteome standards |
| US9297808B2 (en) * | 2010-07-07 | 2016-03-29 | Thermo Fisher Scientific Gmbh | Analyte mass spectrometry quantitation using a universal reporter |
| US10247711B2 (en) | 2013-02-13 | 2019-04-02 | Promega Corporation | Quality control reagents and methods |
| CN105143872B (zh) * | 2013-06-07 | 2019-03-01 | 皮尔斯生物科技有限公司 | 通过质谱分析用复用内标物对蛋白质和蛋白质修饰的绝对定量 |
| WO2019202872A1 (ja) * | 2018-04-16 | 2019-10-24 | 株式会社島津製作所 | 質量分析用キット、微生物識別用キット、試料の調製方法、分析方法および微生物の識別方法 |
| CN109696500B (zh) * | 2019-01-29 | 2021-07-09 | 中国药科大学 | 采用高效液相色谱法测定目标杂质校正因子的方法及应用 |
| WO2025010077A1 (en) * | 2023-07-03 | 2025-01-09 | Agilent Technologies, Inc. | Negative tune standard for mass spectrometry |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4847493A (en) | 1987-10-09 | 1989-07-11 | Masstron, Inc. | Calibration of a mass spectrometer |
| US20060141632A1 (en) * | 2000-07-25 | 2006-06-29 | The Procter & Gamble Co. | New methods and kits for sequencing polypeptides |
| WO2002014856A2 (en) | 2000-08-14 | 2002-02-21 | Isis Innovation Limited | Mass spectrometry |
| GB0021901D0 (en) | 2000-09-06 | 2000-10-25 | Kratos Analytical Ltd | Calibration method |
| CA2419492C (en) * | 2001-03-22 | 2005-07-05 | Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw | Methods and apparatus for gel-free qualitative and quantitative proteome analysis, and uses therefore |
| JP2005521030A (ja) | 2001-07-12 | 2005-07-14 | シファーゲン バイオシステムズ， インコーポレイテッド | 質量分析計の較正方法 |
| WO2003102220A2 (en) * | 2002-06-04 | 2003-12-11 | The Institute For Systems Biology | Methods for high throughput and quantitative proteome analysis |
| US7632686B2 (en) * | 2002-10-03 | 2009-12-15 | Anderson Forschung Group | High sensitivity quantitation of peptides by mass spectrometry |
| US6983213B2 (en) * | 2003-10-20 | 2006-01-03 | Cerno Bioscience Llc | Methods for operating mass spectrometry (MS) instrument systems |
| WO2005124341A2 (en) * | 2004-06-09 | 2005-12-29 | Anderson Forschung Group Llc | Stable isotope labeled polypeptide standards for protein quantitation |
| EP1953542B9 (en) * | 2005-11-08 | 2013-11-13 | Tohoku University | Method of quantifying membrane protein by using mass spectrometer |
| JP5003274B2 (ja) * | 2007-05-16 | 2012-08-15 | 株式会社日立製作所 | 質量分析システムおよび質量分析方法 |
| JP5317336B2 (ja) * | 2009-02-23 | 2013-10-16 | 国立大学法人東北大学 | 質量分析装置を用いたタンパク質定量のための評価用ペプチド、人工標準タンパク質、及びタンパク質の定量方法 |
| EP2572191A1 (en) * | 2010-05-20 | 2013-03-27 | The University of Manitoba | Methods and systems for analysis of peptide sample streams using tandem mass spectroscopy |
| US9297808B2 (en) * | 2010-07-07 | 2016-03-29 | Thermo Fisher Scientific Gmbh | Analyte mass spectrometry quantitation using a universal reporter |
| EP2508537A1 (en) * | 2011-04-04 | 2012-10-10 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Quantitative standard for mass spectrometry of proteins |
| US9163276B2 (en) * | 2011-07-22 | 2015-10-20 | Tohoku University | Method for fabricating stable-isotope-labeled target peptide fragment in mass spectrometry |
| US9388132B2 (en) * | 2011-09-15 | 2016-07-12 | Wisconsin Alumni Research Foundation | Isobaric tandem mass tags for quantitative proteomics and peptidomics |
| US9366678B2 (en) * | 2012-10-25 | 2016-06-14 | Wisconsin Alumni Research Foundation | Neutron encoded mass tags for analyte quantification |
| US10247711B2 (en) | 2013-02-13 | 2019-04-02 | Promega Corporation | Quality control reagents and methods |
| CN105143872B (zh) * | 2013-06-07 | 2019-03-01 | 皮尔斯生物科技有限公司 | 通过质谱分析用复用内标物对蛋白质和蛋白质修饰的绝对定量 |
| EP3746048A4 (en) * | 2018-01-31 | 2021-12-15 | Nx Prenatal Inc. | USE OF CIRCULATING MICROPARTICLES TO STRATIFY THE RISK OF SPONTANEOUS PREMATURE BIRTH |
| WO2020097593A1 (en) * | 2018-11-09 | 2020-05-14 | Nx Prenatal Inc. | Tandem-paired column chemistry for high-throughput proteomic exosome analysis |
-
2014
- 2014-02-13 US US14/180,125 patent/US10247711B2/en active Active
- 2014-02-13 WO PCT/US2014/016289 patent/WO2014127144A2/en not_active Ceased
- 2014-02-13 JP JP2015558133A patent/JP6396337B2/ja active Active
- 2014-02-13 EP EP23194018.0A patent/EP4290231A3/en active Pending
- 2014-02-13 EP EP14751839.3A patent/EP2956768B1/en active Active
-
2018
- 2018-08-29 JP JP2018159973A patent/JP6563574B2/ja active Active
-
2019
- 2019-02-14 US US16/275,417 patent/US10900939B2/en active Active
- 2019-08-23 US US16/549,769 patent/US10908135B2/en active Active
-
2021
- 2021-01-27 US US17/159,923 patent/US11692983B2/en active Active
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