JP2016512232A5 - - Google Patents
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- JP2016512232A5 JP2016512232A5 JP2015562913A JP2015562913A JP2016512232A5 JP 2016512232 A5 JP2016512232 A5 JP 2016512232A5 JP 2015562913 A JP2015562913 A JP 2015562913A JP 2015562913 A JP2015562913 A JP 2015562913A JP 2016512232 A5 JP2016512232 A5 JP 2016512232A5
- Authority
- JP
- Japan
- Prior art keywords
- hydroxypropyl
- carbamate
- chlorophenyl
- group
- dichlorophenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361776926P | 2013-03-12 | 2013-03-12 | |
| US61/776,926 | 2013-03-12 | ||
| PCT/KR2014/002005 WO2014142518A1 (en) | 2013-03-12 | 2014-03-11 | Phenyl carbamate compounds for use in preventing or treating a movement disorder |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016512232A JP2016512232A (ja) | 2016-04-25 |
| JP2016512232A5 true JP2016512232A5 (https=) | 2017-08-31 |
| JP6200526B2 JP6200526B2 (ja) | 2017-09-20 |
Family
ID=51530016
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015562906A Active JP6062077B2 (ja) | 2013-03-12 | 2014-03-07 | 小児てんかん及びてんかん関連症侯群の予防又は治療用フェニルカルバメート化合物｛ｐｈｅｎｙｌｃａｒｂａｍａｔｅｃｏｍｐｏｕｎｄｓｆｏｒｕｓｅｉｎｐｒｅｖｅｎｔｉｎｇｏｒｔｒｅａｔｉｎｇｐｅｄｉａｔｒｉｃｅｐｉｌｅｓｙａｎｄｅｐｉｌｅｓｙ−ｒｅｌａｔｅｄｓｙｎｄｒｏｍｅｓ｝ |
| JP2015562913A Active JP6200526B2 (ja) | 2013-03-12 | 2014-03-11 | 運動障害の予防又は治療用フェニルカルバメート化合物 |
| JP2015562914A Active JP6215971B2 (ja) | 2013-03-12 | 2014-03-11 | てんかん又はてんかん−関連症侯群の予防又は治療用フェニルアルキルカルバメート化合物｛ｐｈｅｎｙｌａｌｋｙｌｃａｒｂａｍａｔｅｃｏｍｐｏｕｎｄｓｆｏｒｕｓｅｉｎｐｒｅｖｅｎｔｉｎｇｏｒｔｒｅａｔｉｎｇｅｐｉｌｅｐｓｙｏｒｅｐｉｌｅｐｓｙ−ｒｅｌａｔｅｄｓｙｎｄｒｏｍｅ｝ |
| JP2015562915A Active JP6062078B2 (ja) | 2013-03-12 | 2014-03-11 | てんかん及びてんかん−関連症侯群の予防又は治療用フェニルカルバメート化合物｛ｐｈｅｎｙｌｃａｒｂａｍａｔｅｃｏｍｐｏｕｎｄｓｆｏｒｕｓｅｉｎｐｒｅｅｎｔｉｎｇｏｒｔｒｅａｔｉｎｇｐｅｄｉａｔｒｉｃｅｐｉｌｅｓｙａｎｄｅｐｉｌｅｓｙ−ｒｅｌａｔｅｄｓｙｎｄｒｏｍｅｓ｝ |
| JP2017133937A Pending JP2017206546A (ja) | 2013-03-12 | 2017-07-07 | てんかん又はてんかん−関連症侯群の予防又は治療用フェニルアルキルカルバメート化合物｛ｐｈｅｎｙｌ ａｌｋｙｌ ｃａｒｂａｍａｔｅ ｃｏｍｐｏｕｎｄｓｆｏｒ ｕｓｅ ｉｎ ｐｒｅｖｅｎｔｉｎｇ ｏｒ ｔｒｅａｔｉｎｇ ｅｐｉｌｅｐｓｙ ｏｒ ｅｐｉｌｅｐｓｙ−ｒｅｌａｔｅｄ ｓｙｎｄｒｏｍｅ｝ |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015562906A Active JP6062077B2 (ja) | 2013-03-12 | 2014-03-07 | 小児てんかん及びてんかん関連症侯群の予防又は治療用フェニルカルバメート化合物｛ｐｈｅｎｙｌｃａｒｂａｍａｔｅｃｏｍｐｏｕｎｄｓｆｏｒｕｓｅｉｎｐｒｅｖｅｎｔｉｎｇｏｒｔｒｅａｔｉｎｇｐｅｄｉａｔｒｉｃｅｐｉｌｅｓｙａｎｄｅｐｉｌｅｓｙ−ｒｅｌａｔｅｄｓｙｎｄｒｏｍｅｓ｝ |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015562914A Active JP6215971B2 (ja) | 2013-03-12 | 2014-03-11 | てんかん又はてんかん−関連症侯群の予防又は治療用フェニルアルキルカルバメート化合物｛ｐｈｅｎｙｌａｌｋｙｌｃａｒｂａｍａｔｅｃｏｍｐｏｕｎｄｓｆｏｒｕｓｅｉｎｐｒｅｖｅｎｔｉｎｇｏｒｔｒｅａｔｉｎｇｅｐｉｌｅｐｓｙｏｒｅｐｉｌｅｐｓｙ−ｒｅｌａｔｅｄｓｙｎｄｒｏｍｅ｝ |
| JP2015562915A Active JP6062078B2 (ja) | 2013-03-12 | 2014-03-11 | てんかん及びてんかん−関連症侯群の予防又は治療用フェニルカルバメート化合物｛ｐｈｅｎｙｌｃａｒｂａｍａｔｅｃｏｍｐｏｕｎｄｓｆｏｒｕｓｅｉｎｐｒｅｅｎｔｉｎｇｏｒｔｒｅａｔｉｎｇｐｅｄｉａｔｒｉｃｅｐｉｌｅｓｙａｎｄｅｐｉｌｅｓｙ−ｒｅｌａｔｅｄｓｙｎｄｒｏｍｅｓ｝ |
| JP2017133937A Pending JP2017206546A (ja) | 2013-03-12 | 2017-07-07 | てんかん又はてんかん−関連症侯群の予防又は治療用フェニルアルキルカルバメート化合物｛ｐｈｅｎｙｌ ａｌｋｙｌ ｃａｒｂａｍａｔｅ ｃｏｍｐｏｕｎｄｓｆｏｒ ｕｓｅ ｉｎ ｐｒｅｖｅｎｔｉｎｇ ｏｒ ｔｒｅａｔｉｎｇ ｅｐｉｌｅｐｓｙ ｏｒ ｅｐｉｌｅｐｓｙ−ｒｅｌａｔｅｄ ｓｙｎｄｒｏｍｅ｝ |
Country Status (7)
| Country | Link |
|---|---|
| US (5) | US9504668B2 (https=) |
| EP (4) | EP2968210B1 (https=) |
| JP (5) | JP6062077B2 (https=) |
| KR (5) | KR101717872B1 (https=) |
| CN (6) | CN105228604A (https=) |
| ES (3) | ES2998534T3 (https=) |
| WO (4) | WO2014142477A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9566261B2 (en) | 2013-03-12 | 2017-02-14 | Bio-Pharm Solutions Co., Ltd. | Phenyl carbamate compound and a composition for preventing or treating a memory loss-related disease comprising the same |
| EP2968210B1 (en) * | 2013-03-12 | 2024-09-11 | Bio-Pharm Solutions Co., Ltd. | Phenyl carbamate compounds for use in preventing or treating pediatric epilesy |
| ES3059582T3 (en) * | 2016-02-29 | 2026-03-23 | Bio Pharm Solutions Co Ltd | Sulfamate derivative compounds, processes for preparing them and their uses |
| MX391363B (es) * | 2016-12-14 | 2025-03-21 | Sk Biopharmaceuticals Co Ltd | Uso de compuesto de carbamato para prevenir, aliviar o tratar temblores o el sindrome de temblor. |
| CN109920550A (zh) * | 2018-12-25 | 2019-06-21 | 天津大学 | 一种基于dMRI研究青少年肌阵挛性癫痫的方法 |
| JP2023539291A (ja) * | 2020-08-31 | 2023-09-13 | バイオ－ファーム ソリューションズ カンパニー リミテッド | 神経変性疾患の予防又は治療用フェニルアルキルカルバメート化合物 |
| KR20230051206A (ko) | 2020-09-10 | 2023-04-17 | (주)바이오팜솔루션즈 | 정신질환 치료 또는 완화용 설파메이트 유도체 화합물 |
| US12054449B2 (en) | 2021-08-05 | 2024-08-06 | Bio-Pharm Solutions Co., Ltd. | Phenylcarbamate crystalline form and method for manufacturing the same |
| CN119552104B (zh) * | 2024-12-03 | 2025-07-15 | 西安瑞谱源生物技术有限公司 | 一种氘代维生素a的制备方法 |
Family Cites Families (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3313692A (en) * | 1958-04-21 | 1967-04-11 | Armour Pharma | Method of inducing calming and muscle relaxation with carbamates |
| US3313699A (en) | 1962-06-26 | 1967-04-11 | Armour Pharma | Compositions for and method of treating the central nervous system |
| US3313697A (en) * | 1962-06-26 | 1967-04-11 | Armour Pharma | Carbamate compositions for and methods of treating the central nervous system |
| US3313696A (en) | 1962-06-26 | 1967-04-11 | Armour Pharmacentical Company | Carbamate sedative compositions and method of use |
| US3313700A (en) * | 1962-07-18 | 1967-04-11 | Armour Pharmacentical Company | Method of treating the central nervous system with substituted phenethyl carbamates and compositions therefor |
| US3265728A (en) * | 1962-07-18 | 1966-08-09 | Armour Pharma | Substituted phenethyl carbamates |
| FR5671M (https=) * | 1965-04-23 | 1968-01-02 | ||
| JPS61271992A (ja) | 1985-05-28 | 1986-12-02 | Central Glass Co Ltd | 光学活性ジオ−ルの製造方法 |
| US5258397A (en) | 1988-11-30 | 1993-11-02 | Novapharme | 3-Isoxazoyl derivatives endowed with anticonvulsant activity, procedure for their preparation and their pharmaceutical compositions |
| FR2686084B1 (fr) * | 1992-01-10 | 1995-12-22 | Bioprojet Soc Civ | Nouveaux derives de l'imidazole, leur preparation et leurs applications therapeutiques. |
| KR100197901B1 (ko) * | 1994-02-21 | 1999-06-15 | 남창우 | 페닐-1,2-에탄디올 광학이성체의 단일 카바메이트 |
| US20100210590A1 (en) * | 1995-09-27 | 2010-08-19 | Northwestern University | Compositions and treatments for seizure-related disorders |
| US5698588A (en) | 1996-01-16 | 1997-12-16 | Yukong Limited | Halogen substituted carbamate compounds from 2-phenyl-1,2-ethanediol |
| US20010034365A1 (en) * | 1996-01-16 | 2001-10-25 | Choi Yong Moon | Halogen substituted carbamate compounds from 2-phenyl-1,2-ethanediol |
| UA65607C2 (uk) * | 1998-03-04 | 2004-04-15 | Орто-Макнейл Фармацевтикал, Інк. | Фармацевтична композиція (варіанти) та спосіб її приготування |
| WO2002051395A1 (en) | 1998-05-28 | 2002-07-04 | Codon Pharmaceuticals, Inc. | Treatment of neurodegenerative diseases |
| AR020115A1 (es) * | 1998-08-06 | 2002-04-10 | Daiichi Seiyaku Co | Agente terapeutico o preventivo para epilepsias rebeldes y uso del compuesto para la produccion de los mismos |
| PL364680A1 (en) * | 2001-02-27 | 2004-12-13 | Ortho-Mcneil Pharmaceutical, Inc. | Carbamate compounds for use in preventing or treating neurodegenerative disorders |
| US6541513B2 (en) | 2001-02-27 | 2003-04-01 | Ortho-Mcneil Pharmaceutical, Inc. | Carbamate compounds for use in preventing or treating psychotic disorders |
| ES2262826T3 (es) | 2001-02-27 | 2006-12-01 | Ortho-Mcneil Pharmaceutical, Inc. | Uso de un compuesto de carbamato en la prevencion o el tratamiento de transtornos de ansiedad. |
| CN1262272C (zh) * | 2001-02-27 | 2006-07-05 | 奥索-麦克尼尔药品公司 | 用于预防或治疗运动障碍的氨基甲酸酯化合物 |
| WO2002067922A1 (en) | 2001-02-27 | 2002-09-06 | Ortho-Mcneil Pharmaceutical, Inc. | Carbamate compounds for use in the treatment of pain |
| US7199135B2 (en) * | 2001-07-05 | 2007-04-03 | H. Lundbeck A/S | Substituted alkyl amido piperidines |
| US20060035944A1 (en) * | 2002-06-11 | 2006-02-16 | Susumu Muto | Remedies for neurodegenerative diseases |
| CA2580640A1 (en) * | 2004-09-16 | 2006-03-30 | Janssen Pharmaceutica N.V. | Methods of treating epileptogensis and epilepsy |
| EP1717235A3 (en) * | 2005-04-29 | 2007-02-28 | Bioprojet | Phenoxypropylpiperidines and -pyrrolidines and their use as histamine H3-receptor ligands |
| US20070021501A1 (en) * | 2005-07-12 | 2007-01-25 | Twyman Roy E | Methods of treating epileptogenesis |
| US7737141B2 (en) | 2006-07-28 | 2010-06-15 | Eisai R&D Management Co., Ltd. | Prodrug of cinnamide compound |
| BRPI0719236A2 (pt) | 2006-10-13 | 2014-07-08 | Janssen Pharmaceutica Nv | Composições de carbamato de fenilalquila |
| CA2673487A1 (en) | 2006-10-13 | 2008-04-24 | Janssen Pharmaceutica Nv | Phenylalkylamino carbamate compositions |
| EA200970424A1 (ru) | 2006-10-27 | 2010-04-30 | Янссен Фармацевтика, Н.В. | Способы лечения кохлеарных и вестибулярных нарушений |
| CA2667949A1 (en) | 2006-10-30 | 2008-05-08 | Janssen Pharmaceutica N.V. | Methods for treating depression |
| US7863499B2 (en) | 2007-02-08 | 2011-01-04 | Albert Einstein College Of Medicine Of Yeshiva University | Model of infantile spasm syndrome |
| MX2009010984A (es) | 2007-04-10 | 2010-01-15 | Sgx Pharmaceuticals Inc | Moduladores de heterociclo cinasa de anillo fusionado. |
| US20110190347A1 (en) | 2008-08-21 | 2011-08-04 | Richter Gedeon Nyrt. | Methods for treating neuropathic pain |
| NZ592008A (en) | 2008-10-02 | 2011-12-22 | Taisho Pharmaceutical Co Ltd | 7-piperidinoalkyl-3,4-dihydroquinolone derivative |
| CN105254557A (zh) * | 2009-05-29 | 2016-01-20 | 拉夸里亚创药株式会社 | 作为钙或钠通道阻滞剂的芳基取代羧酰胺衍生物 |
| EP2461807A1 (en) * | 2009-08-05 | 2012-06-13 | Convergence Pharmaceuticals Limited | Co-therapy for the treatment of epilepsy and related disorders |
| US9018253B2 (en) * | 2010-07-02 | 2015-04-28 | Bio-Pharm Solutions Co., Ltd. | Phenylcarbamate compound and muscle relaxant containing the same |
| CA2803825C (en) * | 2010-07-02 | 2015-12-29 | Bio-Pharm Solutions Co., Ltd. | Phenylcarbamate compound and muscle relaxant containing the same |
| CA2815460C (en) * | 2011-01-13 | 2017-04-18 | Bio-Pharm Solutions Co., Ltd. | Process for preparation of phenyl carbamate derivatives |
| EP2797880B1 (en) * | 2011-12-27 | 2017-03-01 | Bio-Pharm Solutions Co., Ltd. | Phenyl carbamate compounds for use in preventing or treating epilepsy |
| EP2968210B1 (en) * | 2013-03-12 | 2024-09-11 | Bio-Pharm Solutions Co., Ltd. | Phenyl carbamate compounds for use in preventing or treating pediatric epilesy |
| US9566261B2 (en) | 2013-03-12 | 2017-02-14 | Bio-Pharm Solutions Co., Ltd. | Phenyl carbamate compound and a composition for preventing or treating a memory loss-related disease comprising the same |
-
2014
- 2014-03-07 EP EP14762362.3A patent/EP2968210B1/en active Active
- 2014-03-07 JP JP2015562906A patent/JP6062077B2/ja active Active
- 2014-03-07 ES ES14762362T patent/ES2998534T3/es active Active
- 2014-03-07 WO PCT/KR2014/001903 patent/WO2014142477A1/en not_active Ceased
- 2014-03-07 KR KR1020157026389A patent/KR101717872B1/ko active Active
- 2014-03-07 CN CN201480015460.XA patent/CN105228604A/zh active Pending
- 2014-03-07 CN CN201910335069.2A patent/CN109939092B/zh active Active
- 2014-03-11 KR KR1020177013680A patent/KR101992035B1/ko active Active
- 2014-03-11 KR KR1020157026369A patent/KR101739676B1/ko active Active
- 2014-03-11 JP JP2015562913A patent/JP6200526B2/ja active Active
- 2014-03-11 CN CN201480015516.1A patent/CN105188690B/zh not_active Expired - Fee Related
- 2014-03-11 EP EP14765077.4A patent/EP2968213A4/en not_active Withdrawn
- 2014-03-11 CN CN201480015472.2A patent/CN105188689B/zh active Active
- 2014-03-11 EP EP14764227.6A patent/EP2968211B1/en active Active
- 2014-03-11 US US14/774,287 patent/US9504668B2/en active Active
- 2014-03-11 EP EP14764907.3A patent/EP2968212B1/en active Active
- 2014-03-11 KR KR1020157026378A patent/KR20150120518A/ko not_active Ceased
- 2014-03-11 JP JP2015562914A patent/JP6215971B2/ja active Active
- 2014-03-11 ES ES14764227T patent/ES2881850T3/es active Active
- 2014-03-11 ES ES14764907T patent/ES3046835T3/es active Active
- 2014-03-11 WO PCT/KR2014/002006 patent/WO2014142519A1/en not_active Ceased
- 2014-03-11 WO PCT/KR2014/002005 patent/WO2014142518A1/en not_active Ceased
- 2014-03-11 WO PCT/KR2014/002007 patent/WO2014142520A1/en not_active Ceased
- 2014-03-11 JP JP2015562915A patent/JP6062078B2/ja active Active
- 2014-03-11 CN CN202010408166.2A patent/CN111419830B/zh not_active Expired - Fee Related
- 2014-03-11 US US14/775,189 patent/US9682059B2/en active Active
- 2014-03-11 US US14/775,092 patent/US9872847B2/en active Active
- 2014-03-11 KR KR1020157026390A patent/KR101717873B1/ko active Active
- 2014-03-11 US US14/204,298 patent/US20140275243A1/en not_active Abandoned
- 2014-03-11 CN CN201480015456.3A patent/CN105209027A/zh active Pending
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2016
- 2016-06-22 US US15/190,123 patent/US9956197B2/en active Active
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2017
- 2017-07-07 JP JP2017133937A patent/JP2017206546A/ja active Pending
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