JP2016510727A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2016510727A5 JP2016510727A5 JP2015558916A JP2015558916A JP2016510727A5 JP 2016510727 A5 JP2016510727 A5 JP 2016510727A5 JP 2015558916 A JP2015558916 A JP 2015558916A JP 2015558916 A JP2015558916 A JP 2015558916A JP 2016510727 A5 JP2016510727 A5 JP 2016510727A5
- Authority
- JP
- Japan
- Prior art keywords
- abcb5
- stem cells
- isolated
- ocular
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361766424P | 2013-02-19 | 2013-02-19 | |
| US61/766,424 | 2013-02-19 | ||
| PCT/US2014/017076 WO2014130518A1 (en) | 2013-02-19 | 2014-02-19 | Abcb5(+) stem cells for treating ocular disease |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019036040A Division JP2019189600A (ja) | 2013-02-19 | 2019-02-28 | 眼疾患を処置するためのａｂｃｂ５（＋）幹細胞 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016510727A JP2016510727A (ja) | 2016-04-11 |
| JP2016510727A5 true JP2016510727A5 (https=) | 2017-03-30 |
| JP7027026B2 JP7027026B2 (ja) | 2022-03-01 |
Family
ID=51391751
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015558916A Active JP7027026B2 (ja) | 2013-02-19 | 2014-02-19 | 眼疾患を処置するためのａｂｃｂ５（＋）幹細胞 |
| JP2019036040A Pending JP2019189600A (ja) | 2013-02-19 | 2019-02-28 | 眼疾患を処置するためのａｂｃｂ５（＋）幹細胞 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019036040A Pending JP2019189600A (ja) | 2013-02-19 | 2019-02-28 | 眼疾患を処置するためのａｂｃｂ５（＋）幹細胞 |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US9801912B2 (https=) |
| EP (2) | EP2964238B1 (https=) |
| JP (2) | JP7027026B2 (https=) |
| KR (2) | KR102474489B1 (https=) |
| AU (1) | AU2014219026B2 (https=) |
| CA (1) | CA2901931C (https=) |
| DK (1) | DK2964238T3 (https=) |
| ES (1) | ES2860573T3 (https=) |
| WO (1) | WO2014130518A1 (https=) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1290028B1 (en) | 2000-06-05 | 2009-12-23 | The Brigham And Women's Hospital, Inc. | A GENE ENCODING A MULTIDRUG RESISTANCE HUMAN P-GLYCOPROTEIN HOMOLOGUE ON CHROMOSOME 7p15-21 AND USES THEREOF |
| HUE059011T2 (hu) | 2006-05-31 | 2022-09-28 | Childrens Medical Center | Immunmodulátorként szolgáló ABC5-pozitív mezenchimális õssejtek |
| DK2155248T3 (en) | 2007-04-12 | 2015-09-14 | Brigham & Womens Hospital | Targeting abcb5 for cancer therapy |
| US11542328B2 (en) | 2008-11-14 | 2023-01-03 | The Brigham And Women's Hospital, Inc. | Therapeutic and diagnostic methods relating to cancer stem cells |
| PT3130923T (pt) | 2008-11-14 | 2020-06-17 | Brigham & Womens Hospital Inc | Métodos terapêuticos relacionados com células estaminais |
| AU2014219026B2 (en) | 2013-02-19 | 2018-11-29 | Children's Medical Center Corporation | ABCB5(+) stem cells for treating ocular disease |
| EP4008369A1 (en) | 2013-05-10 | 2022-06-08 | Children's Medical Center Corporation | Wound healing and tissue engineering |
| EP4036228A1 (en) | 2015-11-13 | 2022-08-03 | Avellino Lab USA, Inc. | Methods for the treatment of corneal dystrophies |
| WO2019210109A1 (en) | 2018-04-25 | 2019-10-31 | Children's Medical Center Corporation | Abcb5 ligands and substrates |
| WO2020021535A1 (en) * | 2018-07-22 | 2020-01-30 | Minovia Therapeutics Ltd. | Mitochondrial augmentation therapy of ocular diseases |
| EP3823646A4 (en) | 2018-07-22 | 2022-06-08 | Minovia Therapeutics Ltd. | Mitochondrial augmentation therapy of brain diseases |
| EP3823644A4 (en) | 2018-07-22 | 2022-06-08 | Minovia Therapeutics Ltd. | MITOCHONDRIAL AUGMENTATION THERAPY OF PANCREATIC DISEASES |
| JP7586811B2 (ja) | 2018-07-22 | 2024-11-19 | ミノヴィア セラピューティクス リミテッド | 腎臓疾患のミトコンドリア増強療法 |
| AU2019311859B2 (en) * | 2018-07-22 | 2025-12-18 | Minovia Therapeutics Ltd. | Mitochondrial augmentation therapy for primary mitochondrial diseases |
| KR20210145178A (ko) * | 2019-04-01 | 2021-12-01 | 스템사이트 오와이 | Abcg2-양성 각막 주변부 줄기 세포를 수득 또는 유지하는 방법 |
| WO2021092564A1 (en) * | 2019-11-07 | 2021-05-14 | Massachusetts Eye And Ear Infirmary | Cultivated autologous limbal epithelial cell (calec) transplantation |
| EP3842079A1 (en) * | 2019-12-24 | 2021-06-30 | Universiteit Antwerpen | Ophthalmological device for the treatment of lscd and substrate for use in same |
| US20230148432A1 (en) * | 2020-03-30 | 2023-05-11 | Children's Medical Center Corporation | Use of stem cells for treatment of excessive inflammation |
| BR112022019609A2 (pt) | 2020-03-31 | 2022-11-29 | Minovia Therapeutics Ltd | Células geneticamente modificadas enriquecidas com mitocôndrias e usos das mesmas |
| US20240335562A1 (en) * | 2021-08-04 | 2024-10-10 | Alpine Biotherapeutics Corporation | Sustainable ocular cell-mediated intraocular delivery of cellular therapeutics for treatment of ocular diseases or disorders |
| KR20230129828A (ko) | 2022-03-02 | 2023-09-11 | 포항공과대학교 산학협력단 | 안구 후방 질환 또는 손상의 예방 또는 치료용 조성물 |
| KR102913194B1 (ko) | 2022-03-03 | 2026-01-19 | 서울대학교병원 | 안구건조증 또는 마이봄샘 기능장애의 예방, 개선, 또는 치료용 조성물 |
| CN115074368B (zh) * | 2022-06-09 | 2023-08-08 | 澳门科技大学 | 一种耐药型类风湿性关节炎动物模型的构建及其应用 |
| WO2025090565A1 (en) * | 2023-10-23 | 2025-05-01 | The Children's Medical Center Corporation | Abcb5-targeted stem cell reprogramming and anti-aging strategies |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5434075A (en) | 1992-03-20 | 1995-07-18 | Board Of Trustees Of The University Of Illinois | Monoclonal antibody to a human MDR1 multidrug resistance gene product, and uses |
| US5837258A (en) | 1991-08-30 | 1998-11-17 | University Of South Florida | Induction of tissue, bone or cartilage formation using connective tissue growth factor |
| US6231881B1 (en) | 1992-02-24 | 2001-05-15 | Anton-Lewis Usala | Medium and matrix for long-term proliferation of cells |
| US5906934A (en) | 1995-03-14 | 1999-05-25 | Morphogen Pharmaceuticals, Inc. | Mesenchymal stem cells for cartilage repair |
| ATE439849T1 (de) | 1996-04-19 | 2009-09-15 | Osiris Therapeutics Inc | Die wiederherstellung und verstärkung von knochen mittels mesenchymalen stammzellen |
| US6152142A (en) | 1997-02-28 | 2000-11-28 | Tseng; Scheffer C. G. | Grafts made from amniotic membrane; methods of separating, preserving, and using such grafts in surgeries |
| DE19722075C1 (de) | 1997-05-27 | 1998-10-01 | Wilhelm Dr Med Fleischmann | Vorrichtung zur Applikation von Wirkstoffen an einer Wundoberfläche |
| AU749675B2 (en) | 1998-03-13 | 2002-07-04 | Mesoblast International Sarl | Uses for human non-autologous mesenchymal stem cells |
| US6368636B1 (en) | 1998-03-18 | 2002-04-09 | Osiris Therapeutics, Inc. | Mesenchymal stem cells for prevention and treatment of immune responses in transplantation |
| PT1066060E (pt) | 1998-04-03 | 2003-12-31 | Osiris Therapeutics Inc | Celulas estaminais mesenquimais como imunossupressores |
| AU4221399A (en) | 1998-05-29 | 1999-12-13 | Osiris Therapeutics, Inc. | Human cd45+ and/or fibroblast + mesenchymal stem cells |
| PL366290A1 (en) | 1999-11-29 | 2005-01-24 | Hill-Rom Services, Inc. | Wound treatment apparatus |
| EP1290028B1 (en) | 2000-06-05 | 2009-12-23 | The Brigham And Women's Hospital, Inc. | A GENE ENCODING A MULTIDRUG RESISTANCE HUMAN P-GLYCOPROTEIN HOMOLOGUE ON CHROMOSOME 7p15-21 AND USES THEREOF |
| AU2002211389A1 (en) | 2000-10-03 | 2002-04-15 | California Institute Of Technology | Microfluidic devices and methods of use |
| US6695824B2 (en) | 2001-04-16 | 2004-02-24 | The United States Of America As Represented By The Secretary Of The Army | Wound dressing system |
| US6905678B2 (en) | 2001-07-07 | 2005-06-14 | Crucell Holland B.V. | Gene delivery vectors with cell type specificity for mesenchymal stem cells |
| US8034904B2 (en) | 2002-06-14 | 2011-10-11 | Immunogen Inc. | Anti-IGF-I receptor antibody |
| US20050186672A1 (en) | 2004-01-27 | 2005-08-25 | Reliance Life Sciences Pvt. Ltd. | Tissue system with undifferentiated stem cells derived from corneal limbus |
| WO2006103685A2 (en) | 2005-03-28 | 2006-10-05 | Vision Research Foundation | A method for cultivating cells derived from corneal limbal tissue and cells deived from corneal limbal tissue |
| IL296832A (en) | 2005-10-18 | 2022-11-01 | Nat Jewish Health | Process of preparing red blood cells using conditionally immortalized long-term hematopoietic stem cells and erythropoietin |
| HUE059011T2 (hu) | 2006-05-31 | 2022-09-28 | Childrens Medical Center | Immunmodulátorként szolgáló ABC5-pozitív mezenchimális õssejtek |
| GB0610778D0 (en) | 2006-05-31 | 2006-07-12 | Het Nl Kanker I | Phosphatidylinositol phospahte and apoptosis |
| DK2155248T3 (en) | 2007-04-12 | 2015-09-14 | Brigham & Womens Hospital | Targeting abcb5 for cancer therapy |
| US9011840B2 (en) | 2008-03-14 | 2015-04-21 | The Board Of Trustees Of The University Of Illinois | Activated mesenchymal stem cells for wound healing and impaired tissue regeneration |
| PT3130923T (pt) | 2008-11-14 | 2020-06-17 | Brigham & Womens Hospital Inc | Métodos terapêuticos relacionados com células estaminais |
| WO2010065711A1 (en) | 2008-12-04 | 2010-06-10 | Adimab, Inc. | An abcb5 epitope and antibodies thereto for the treatment of cancer |
| GB0908927D0 (en) * | 2009-05-22 | 2009-07-01 | Univ Reading The | Synthetic graft |
| US20140309738A1 (en) | 2011-06-01 | 2014-10-16 | The Board Of Trustees Of The University Of Illinois | Membrane-Scaffold Composites for Tissue Engineering Applications |
| AU2014219026B2 (en) * | 2013-02-19 | 2018-11-29 | Children's Medical Center Corporation | ABCB5(+) stem cells for treating ocular disease |
| EP4008369A1 (en) | 2013-05-10 | 2022-06-08 | Children's Medical Center Corporation | Wound healing and tissue engineering |
| WO2016179576A1 (en) | 2015-05-07 | 2016-11-10 | Bioxcel Corporation | Novel immunomodulatory therapeutic strategies targeting tumors in cancer |
-
2014
- 2014-02-19 AU AU2014219026A patent/AU2014219026B2/en active Active
- 2014-02-19 DK DK14754427.4T patent/DK2964238T3/da active
- 2014-02-19 KR KR1020227011673A patent/KR102474489B1/ko active Active
- 2014-02-19 ES ES14754427T patent/ES2860573T3/es active Active
- 2014-02-19 JP JP2015558916A patent/JP7027026B2/ja active Active
- 2014-02-19 KR KR1020157025733A patent/KR102385934B1/ko active Active
- 2014-02-19 EP EP14754427.4A patent/EP2964238B1/en active Active
- 2014-02-19 EP EP21150996.3A patent/EP3865573A1/en active Pending
- 2014-02-19 US US14/768,885 patent/US9801912B2/en active Active
- 2014-02-19 WO PCT/US2014/017076 patent/WO2014130518A1/en not_active Ceased
- 2014-02-19 CA CA2901931A patent/CA2901931C/en active Active
-
2017
- 2017-10-30 US US15/796,920 patent/US11129854B2/en active Active
-
2019
- 2019-02-28 JP JP2019036040A patent/JP2019189600A/ja active Pending
-
2021
- 2021-09-27 US US17/486,855 patent/US20220118024A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2016510727A5 (https=) | ||
| Delplace et al. | Delivery strategies for treatment of age-related ocular diseases: From a biological understanding to biomaterial solutions | |
| Matsuura et al. | Cell sheet approach for tissue engineering and regenerative medicine | |
| JP2018086274A5 (https=) | ||
| MY171135A (en) | Antibodies specific for tgf-beta | |
| JP2015159895A5 (https=) | ||
| WO2012158952A8 (en) | Treatment of intervertebral disc degeneration using human umbilical cord tissue-derived cells and hydrogel | |
| WO2009061447A3 (en) | Use of umbilical cord blood in the treatment of premature birth complications | |
| PH12017502283A1 (en) | A method of treatment | |
| JP2015131795A5 (https=) | ||
| HK1256130A1 (zh) | 用於嵌合抗原受体和其他受体的表达的t细胞 | |
| EP4349854A3 (en) | Pd1-cd28 fusion proteins and their use in medicine | |
| JP2010285434A5 (https=) | ||
| EA201301277A1 (ru) | Композиции и способы лечения заболеваний сетчатки | |
| WO2013013025A3 (en) | Anti-cxcr4 antibodies and methods of use | |
| EP4699624A3 (en) | Cell suspension and use thereof | |
| CA2862332C (en) | Anti-asic1 antibodies and uses thereof | |
| JP2016539641A5 (https=) | ||
| WO2014028668A3 (en) | Stem cell enhancing therapeutics | |
| WO2015076717A3 (en) | Mscs in the treatment of cardiac disorders | |
| BR112018012070A2 (pt) | método para a produção de tecidos/ órgãos utilizando células sanguíneas | |
| ZA201907371B (en) | Methods and compositions for treating allergic ocular diseases | |
| ZA202106559B (en) | Compositions of matter with activity to remove lipofuscin from retinal cells | |
| JP2013507945A5 (https=) | ||
| WO2012021891A3 (en) | Compositions, kits and methods for treatment of complement-related disorders |