JP2013507945A5 - - Google Patents
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- Publication number
- JP2013507945A5 JP2013507945A5 JP2012534715A JP2012534715A JP2013507945A5 JP 2013507945 A5 JP2013507945 A5 JP 2013507945A5 JP 2012534715 A JP2012534715 A JP 2012534715A JP 2012534715 A JP2012534715 A JP 2012534715A JP 2013507945 A5 JP2013507945 A5 JP 2013507945A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- peripheral blood
- regulatory
- contacting
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 claims 15
- 239000000427 antigen Substances 0.000 claims 12
- 102000036639 antigens Human genes 0.000 claims 12
- 108091007433 antigens Proteins 0.000 claims 12
- 210000000265 leukocyte Anatomy 0.000 claims 10
- 210000005259 peripheral blood Anatomy 0.000 claims 10
- 239000011886 peripheral blood Substances 0.000 claims 10
- 210000002901 mesenchymal stem cell Anatomy 0.000 claims 9
- 210000003289 regulatory T cell Anatomy 0.000 claims 9
- 210000002950 fibroblast Anatomy 0.000 claims 8
- 238000004519 manufacturing process Methods 0.000 claims 5
- 210000004027 cell Anatomy 0.000 claims 4
- 102000004457 Granulocyte-Macrophage Colony-Stimulating Factor Human genes 0.000 claims 3
- 108010017213 Granulocyte-Macrophage Colony-Stimulating Factor Proteins 0.000 claims 3
- 108090000978 Interleukin-4 Proteins 0.000 claims 3
- 239000003795 chemical substances by application Substances 0.000 claims 3
- 108010002350 Interleukin-2 Proteins 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 201000006417 multiple sclerosis Diseases 0.000 claims 2
- 101001057504 Homo sapiens Interferon-stimulated gene 20 kDa protein Proteins 0.000 claims 1
- 101001055144 Homo sapiens Interleukin-2 receptor subunit alpha Proteins 0.000 claims 1
- 102100026878 Interleukin-2 receptor subunit alpha Human genes 0.000 claims 1
- 210000000577 adipose tissue Anatomy 0.000 claims 1
- 208000037765 diseases and disorders Diseases 0.000 claims 1
- 230000001105 regulatory effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0918615.6A GB0918615D0 (en) | 2009-10-23 | 2009-10-23 | Cell populations having immunoregulatory activity, methods for the preparation and uses thereof |
| GB0918615.6 | 2009-10-23 | ||
| PCT/EP2010/066007 WO2011048222A1 (en) | 2009-10-23 | 2010-10-22 | Cell populations having immunoregulatory activity, methods for the preparation and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013507945A JP2013507945A (ja) | 2013-03-07 |
| JP2013507945A5 true JP2013507945A5 (https=) | 2013-12-12 |
Family
ID=41426608
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012534715A Pending JP2013507945A (ja) | 2009-10-23 | 2010-10-22 | 免疫調節活性を有する細胞集団、その製造方法及び使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US9969976B2 (https=) |
| EP (1) | EP2491115B1 (https=) |
| JP (1) | JP2013507945A (https=) |
| ES (1) | ES2479543T3 (https=) |
| GB (1) | GB0918615D0 (https=) |
| WO (1) | WO2011048222A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20140348808A1 (en) * | 2011-05-19 | 2014-11-27 | Olga De La Rosa | Cell populations having immunoregulatory activity, methods for the preparation and uses thereof |
| ES2434853B1 (es) * | 2012-06-12 | 2014-09-30 | Fundación Centro Nacional De Investigaciones Cardiovasculares Carlos Iii | Marcador molecular de potencia terapéutica de células madre mesenquimales humanas y sus usos |
| JP7118886B2 (ja) | 2015-06-03 | 2022-08-16 | エアラン セル テクノロジーズ， インコーポレイテッド | 幹細胞からの有益因子の産生および送達のための方法およびデバイス |
| US11291689B2 (en) | 2015-06-03 | 2022-04-05 | Aelan Cell Technologies, Inc. | Methods and devices for the production and delivery of beneficial factors from adipose-derived stem cells |
| US12233094B2 (en) | 2017-11-29 | 2025-02-25 | Spinalcyte, Llc | Interaction of fibroblasts and immune cells for activation and uses thereof |
| EP4045065A4 (en) * | 2019-10-15 | 2023-08-30 | Figene, LLC | Fibroblast-based immunotherapy of graves disease |
| CN111979186B (zh) * | 2020-08-21 | 2022-04-08 | 遵义医科大学附属医院 | 一种快速高效体外扩增人间充质干细胞的方法及应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7048922B2 (en) * | 2002-05-29 | 2006-05-23 | Demao Yang | Stimulation of hematopoiesis by ex vivo activated immune cells |
| WO2005094353A2 (en) | 2004-03-29 | 2005-10-13 | Cytomatrix, Llc | Methods for production of regulatory t cells and uses thereof |
| JP2006280307A (ja) | 2005-04-01 | 2006-10-19 | Kyoto Univ | 制御性ｔ細胞の製造方法 |
| KR101536239B1 (ko) * | 2005-09-23 | 2015-07-13 | 셀레릭스, 에스.엘. | 면역조절활성을 갖는 세포 개체군, 분리 방법 및 용도 |
| US8241621B2 (en) * | 2006-12-18 | 2012-08-14 | Medistem Laboratories | Stem cell mediated treg activation/expansion for therapeutic immune modulation |
| GB0820397D0 (en) * | 2008-11-07 | 2008-12-17 | Cellerix Sa | Cells, nucleic acid constructs, cells comprising said constructs and methods utilizing said cells in the treatment of diseases |
-
2009
- 2009-10-23 GB GBGB0918615.6A patent/GB0918615D0/en not_active Ceased
-
2010
- 2010-10-22 WO PCT/EP2010/066007 patent/WO2011048222A1/en not_active Ceased
- 2010-10-22 EP EP10768496.1A patent/EP2491115B1/en active Active
- 2010-10-22 JP JP2012534715A patent/JP2013507945A/ja active Pending
- 2010-10-22 US US13/503,542 patent/US9969976B2/en active Active
- 2010-10-22 ES ES10768496.1T patent/ES2479543T3/es active Active
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