JP2016510727A5 - - Google Patents
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- Publication number
- JP2016510727A5 JP2016510727A5 JP2015558916A JP2015558916A JP2016510727A5 JP 2016510727 A5 JP2016510727 A5 JP 2016510727A5 JP 2015558916 A JP2015558916 A JP 2015558916A JP 2015558916 A JP2015558916 A JP 2015558916A JP 2016510727 A5 JP2016510727 A5 JP 2016510727A5
- Authority
- JP
- Japan
- Prior art keywords
- abcb5
- stem cells
- isolated
- ocular
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361766424P | 2013-02-19 | 2013-02-19 | |
| US61/766,424 | 2013-02-19 | ||
| PCT/US2014/017076 WO2014130518A1 (en) | 2013-02-19 | 2014-02-19 | Abcb5(+) stem cells for treating ocular disease |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019036040A Division JP2019189600A (ja) | 2013-02-19 | 2019-02-28 | 眼疾患を処置するためのabcb5(+)幹細胞 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016510727A JP2016510727A (ja) | 2016-04-11 |
| JP2016510727A5 true JP2016510727A5 (enExample) | 2017-03-30 |
| JP7027026B2 JP7027026B2 (ja) | 2022-03-01 |
Family
ID=51391751
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015558916A Active JP7027026B2 (ja) | 2013-02-19 | 2014-02-19 | 眼疾患を処置するためのabcb5(+)幹細胞 |
| JP2019036040A Pending JP2019189600A (ja) | 2013-02-19 | 2019-02-28 | 眼疾患を処置するためのabcb5(+)幹細胞 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019036040A Pending JP2019189600A (ja) | 2013-02-19 | 2019-02-28 | 眼疾患を処置するためのabcb5(+)幹細胞 |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US9801912B2 (enExample) |
| EP (2) | EP2964238B1 (enExample) |
| JP (2) | JP7027026B2 (enExample) |
| KR (2) | KR102385934B1 (enExample) |
| AU (1) | AU2014219026B2 (enExample) |
| CA (1) | CA2901931C (enExample) |
| DK (1) | DK2964238T3 (enExample) |
| ES (1) | ES2860573T3 (enExample) |
| WO (1) | WO2014130518A1 (enExample) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1290028B1 (en) | 2000-06-05 | 2009-12-23 | The Brigham And Women's Hospital, Inc. | A GENE ENCODING A MULTIDRUG RESISTANCE HUMAN P-GLYCOPROTEIN HOMOLOGUE ON CHROMOSOME 7p15-21 AND USES THEREOF |
| PT2772535T (pt) | 2006-05-31 | 2022-07-04 | Childrens Medical Center | Células estaminais mesenquimais abcb5 positivas como imunomoduladores |
| DK2644205T3 (en) | 2007-04-12 | 2018-09-24 | Brigham & Womens Hospital Inc | Targeting ABCB5 for Cancer Therapy |
| ES2796111T3 (es) | 2008-11-14 | 2020-11-25 | Brigham & Womens Hospital Inc | Métodos terapéuticos relacionados con células madre cancerosas |
| US11542328B2 (en) | 2008-11-14 | 2023-01-03 | The Brigham And Women's Hospital, Inc. | Therapeutic and diagnostic methods relating to cancer stem cells |
| KR102385934B1 (ko) | 2013-02-19 | 2022-04-13 | 칠드런'즈 메디컬 센터 코포레이션 | 안구 질환을 치료하기 위한 abcb5(+) 줄기 세포 |
| WO2014182994A1 (en) | 2013-05-10 | 2014-11-13 | Children's Medical Center Corporation | Wound healing and tissue engineering |
| EP4036228A1 (en) * | 2015-11-13 | 2022-08-03 | Avellino Lab USA, Inc. | Methods for the treatment of corneal dystrophies |
| JP7611701B2 (ja) | 2018-04-25 | 2025-01-10 | ザ チルドレンズ メディカル センター コーポレーション | Abcb5のリガンドおよび基質 |
| JP2021531288A (ja) | 2018-07-22 | 2021-11-18 | ミノヴィア セラピューティクス リミテッド | 眼疾患のミトコンドリア増強療法 |
| WO2020021538A1 (en) | 2018-07-22 | 2020-01-30 | Minovia Therapeutics Ltd. | Mitochondrial augmentation therapy of brain diseases |
| EP3823644A4 (en) | 2018-07-22 | 2022-06-08 | Minovia Therapeutics Ltd. | MITOCHONDRIAL AUGMENTATION THERAPY OF PANCREATIC DISEASES |
| AU2019311859B2 (en) * | 2018-07-22 | 2025-12-18 | Minovia Therapeutics Ltd. | Mitochondrial augmentation therapy for primary mitochondrial diseases |
| JP7586811B2 (ja) | 2018-07-22 | 2024-11-19 | ミノヴィア セラピューティクス リミテッド | 腎臓疾患のミトコンドリア増強療法 |
| WO2020201629A1 (en) * | 2019-04-01 | 2020-10-08 | Tampere University Foundation Sr | Method for obtaining or maintaining abcg2-positive corneal limbal stem cells |
| WO2021092564A1 (en) * | 2019-11-07 | 2021-05-14 | Massachusetts Eye And Ear Infirmary | Cultivated autologous limbal epithelial cell (calec) transplantation |
| EP3842079A1 (en) * | 2019-12-24 | 2021-06-30 | Universiteit Antwerpen | Ophthalmological device for the treatment of lscd and substrate for use in same |
| WO2021202570A1 (en) * | 2020-03-30 | 2021-10-07 | Children's Medical Center Corporation | Use of stem cells for treatment of excessive inflammation |
| WO2023014892A1 (en) * | 2021-08-04 | 2023-02-09 | Alpine Biotherapeutics Corporation | Sustainable ocular cell-mediated intraocular delivery of cellular therapeutics for treatment of ocular diseases or disorders |
| KR20230129828A (ko) | 2022-03-02 | 2023-09-11 | 포항공과대학교 산학협력단 | 안구 후방 질환 또는 손상의 예방 또는 치료용 조성물 |
| KR102913194B1 (ko) | 2022-03-03 | 2026-01-19 | 서울대학교병원 | 안구건조증 또는 마이봄샘 기능장애의 예방, 개선, 또는 치료용 조성물 |
| CN115074368B (zh) * | 2022-06-09 | 2023-08-08 | 澳门科技大学 | 一种耐药型类风湿性关节炎动物模型的构建及其应用 |
| WO2025090565A1 (en) * | 2023-10-23 | 2025-05-01 | The Children's Medical Center Corporation | Abcb5-targeted stem cell reprogramming and anti-aging strategies |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5434075A (en) | 1992-03-20 | 1995-07-18 | Board Of Trustees Of The University Of Illinois | Monoclonal antibody to a human MDR1 multidrug resistance gene product, and uses |
| US5837258A (en) | 1991-08-30 | 1998-11-17 | University Of South Florida | Induction of tissue, bone or cartilage formation using connective tissue growth factor |
| US6231881B1 (en) | 1992-02-24 | 2001-05-15 | Anton-Lewis Usala | Medium and matrix for long-term proliferation of cells |
| US5906934A (en) | 1995-03-14 | 1999-05-25 | Morphogen Pharmaceuticals, Inc. | Mesenchymal stem cells for cartilage repair |
| CA2251983C (en) | 1996-04-19 | 2003-12-16 | Sudhakar Kadiyala | Regeneration and augmentation of bone using mesenchymal stem cells |
| US6152142A (en) | 1997-02-28 | 2000-11-28 | Tseng; Scheffer C. G. | Grafts made from amniotic membrane; methods of separating, preserving, and using such grafts in surgeries |
| DE19722075C1 (de) | 1997-05-27 | 1998-10-01 | Wilhelm Dr Med Fleischmann | Vorrichtung zur Applikation von Wirkstoffen an einer Wundoberfläche |
| PT1062321E (pt) | 1998-03-13 | 2005-05-31 | Osiris Therapeutics Inc | Utilizacoes para celulas estaminais mesenquimais humanas nao autologas |
| US6368636B1 (en) | 1998-03-18 | 2002-04-09 | Osiris Therapeutics, Inc. | Mesenchymal stem cells for prevention and treatment of immune responses in transplantation |
| US6797269B2 (en) | 1998-04-03 | 2004-09-28 | Osiris Therapeutics, Inc. | Mesenchymal stem cells as immunosuppressants |
| ES2292245T3 (es) | 1998-05-29 | 2008-03-01 | Osiris Therapeutics, Inc. | Celulas madre mesenquimaticas cd45+ y/o fibroblasto+humanas. |
| KR20030009325A (ko) | 1999-11-29 | 2003-01-29 | 힐-롬 서비시즈, 인크. | 상처 치료 장치 |
| EP1290028B1 (en) | 2000-06-05 | 2009-12-23 | The Brigham And Women's Hospital, Inc. | A GENE ENCODING A MULTIDRUG RESISTANCE HUMAN P-GLYCOPROTEIN HOMOLOGUE ON CHROMOSOME 7p15-21 AND USES THEREOF |
| US7258774B2 (en) | 2000-10-03 | 2007-08-21 | California Institute Of Technology | Microfluidic devices and methods of use |
| US6695824B2 (en) | 2001-04-16 | 2004-02-24 | The United States Of America As Represented By The Secretary Of The Army | Wound dressing system |
| US6905678B2 (en) | 2001-07-07 | 2005-06-14 | Crucell Holland B.V. | Gene delivery vectors with cell type specificity for mesenchymal stem cells |
| US8034904B2 (en) | 2002-06-14 | 2011-10-11 | Immunogen Inc. | Anti-IGF-I receptor antibody |
| US20050186672A1 (en) * | 2004-01-27 | 2005-08-25 | Reliance Life Sciences Pvt. Ltd. | Tissue system with undifferentiated stem cells derived from corneal limbus |
| WO2006103685A2 (en) * | 2005-03-28 | 2006-10-05 | Vision Research Foundation | A method for cultivating cells derived from corneal limbal tissue and cells deived from corneal limbal tissue |
| KR101441693B1 (ko) | 2005-10-18 | 2014-09-25 | 내셔날 쥬이쉬 헬스 | 조건부 불멸화 장기 줄기 세포 및 상기 세포의 제조 및사용 방법 |
| GB0610778D0 (en) | 2006-05-31 | 2006-07-12 | Het Nl Kanker I | Phosphatidylinositol phospahte and apoptosis |
| PT2772535T (pt) | 2006-05-31 | 2022-07-04 | Childrens Medical Center | Células estaminais mesenquimais abcb5 positivas como imunomoduladores |
| DK2644205T3 (en) | 2007-04-12 | 2018-09-24 | Brigham & Womens Hospital Inc | Targeting ABCB5 for Cancer Therapy |
| US9011840B2 (en) | 2008-03-14 | 2015-04-21 | The Board Of Trustees Of The University Of Illinois | Activated mesenchymal stem cells for wound healing and impaired tissue regeneration |
| ES2796111T3 (es) | 2008-11-14 | 2020-11-25 | Brigham & Womens Hospital Inc | Métodos terapéuticos relacionados con células madre cancerosas |
| WO2010065711A1 (en) | 2008-12-04 | 2010-06-10 | Adimab, Inc. | An abcb5 epitope and antibodies thereto for the treatment of cancer |
| GB0908927D0 (en) * | 2009-05-22 | 2009-07-01 | Univ Reading The | Synthetic graft |
| WO2013002953A1 (en) | 2011-06-01 | 2013-01-03 | The Board Of Trustees Of The University Of Illinois | Membrane-scaffold composites for tissue engineering applications |
| KR102385934B1 (ko) | 2013-02-19 | 2022-04-13 | 칠드런'즈 메디컬 센터 코포레이션 | 안구 질환을 치료하기 위한 abcb5(+) 줄기 세포 |
| WO2014182994A1 (en) | 2013-05-10 | 2014-11-13 | Children's Medical Center Corporation | Wound healing and tissue engineering |
| WO2016179576A1 (en) | 2015-05-07 | 2016-11-10 | Bioxcel Corporation | Novel immunomodulatory therapeutic strategies targeting tumors in cancer |
-
2014
- 2014-02-19 KR KR1020157025733A patent/KR102385934B1/ko active Active
- 2014-02-19 AU AU2014219026A patent/AU2014219026B2/en active Active
- 2014-02-19 KR KR1020227011673A patent/KR102474489B1/ko active Active
- 2014-02-19 DK DK14754427.4T patent/DK2964238T3/da active
- 2014-02-19 JP JP2015558916A patent/JP7027026B2/ja active Active
- 2014-02-19 US US14/768,885 patent/US9801912B2/en active Active
- 2014-02-19 WO PCT/US2014/017076 patent/WO2014130518A1/en not_active Ceased
- 2014-02-19 ES ES14754427T patent/ES2860573T3/es active Active
- 2014-02-19 CA CA2901931A patent/CA2901931C/en active Active
- 2014-02-19 EP EP14754427.4A patent/EP2964238B1/en active Active
- 2014-02-19 EP EP21150996.3A patent/EP3865573A1/en active Pending
-
2017
- 2017-10-30 US US15/796,920 patent/US11129854B2/en active Active
-
2019
- 2019-02-28 JP JP2019036040A patent/JP2019189600A/ja active Pending
-
2021
- 2021-09-27 US US17/486,855 patent/US20220118024A1/en active Pending
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