JP2016509579A5 - - Google Patents
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- Publication number
- JP2016509579A5 JP2016509579A5 JP2015548837A JP2015548837A JP2016509579A5 JP 2016509579 A5 JP2016509579 A5 JP 2016509579A5 JP 2015548837 A JP2015548837 A JP 2015548837A JP 2015548837 A JP2015548837 A JP 2015548837A JP 2016509579 A5 JP2016509579 A5 JP 2016509579A5
- Authority
- JP
- Japan
- Prior art keywords
- dimethyl
- dione
- pyrimido
- dihydro
- pyrrolo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261739335P | 2012-12-19 | 2012-12-19 | |
| US61/739,335 | 2012-12-19 | ||
| US201361906141P | 2013-11-19 | 2013-11-19 | |
| US61/906,141 | 2013-11-19 | ||
| PCT/IB2013/061043 WO2014097148A1 (en) | 2012-12-19 | 2013-12-17 | Tricyclic compounds for inhibiting the cftr channel |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016509579A JP2016509579A (ja) | 2016-03-31 |
| JP2016509579A5 true JP2016509579A5 (enExample) | 2017-01-26 |
| JP6284546B2 JP6284546B2 (ja) | 2018-02-28 |
Family
ID=50030372
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015548837A Expired - Fee Related JP6284546B2 (ja) | 2012-12-19 | 2013-12-17 | Ｃｆｔｒチャネルを阻害するための三環式化合物 |
Country Status (25)
| Country | Link |
|---|---|
| US (2) | US9359381B2 (enExample) |
| EP (1) | EP2935278B1 (enExample) |
| JP (1) | JP6284546B2 (enExample) |
| KR (1) | KR20150097660A (enExample) |
| CN (1) | CN105143230B (enExample) |
| AP (1) | AP2015008539A0 (enExample) |
| AR (1) | AR094122A1 (enExample) |
| AU (1) | AU2013365739A1 (enExample) |
| BR (1) | BR112015014292A2 (enExample) |
| CA (1) | CA2895660A1 (enExample) |
| CL (1) | CL2015001730A1 (enExample) |
| CR (1) | CR20150325A (enExample) |
| CU (1) | CU20150066A7 (enExample) |
| EA (1) | EA201591177A1 (enExample) |
| ES (1) | ES2628369T3 (enExample) |
| HK (1) | HK1209741A1 (enExample) |
| IL (1) | IL239389A0 (enExample) |
| MX (1) | MX2015007939A (enExample) |
| PE (1) | PE20151055A1 (enExample) |
| PH (1) | PH12015501386A1 (enExample) |
| SG (1) | SG11201504594QA (enExample) |
| TN (1) | TN2015000279A1 (enExample) |
| TW (1) | TW201429974A (enExample) |
| UY (1) | UY35211A (enExample) |
| WO (1) | WO2014097148A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9056867B2 (en) | 2011-09-16 | 2015-06-16 | Novartis Ag | N-substituted heterocyclyl carboxamides |
| EP2935278B1 (en) | 2012-12-19 | 2017-03-15 | Novartis AG | Tricyclic compounds for inhibiting the cftr channel |
| KR20150095925A (ko) | 2012-12-19 | 2015-08-21 | 노파르티스 아게 | Cftr 억제제로서의 트리시클릭 화합물 |
| CN106715536B (zh) * | 2014-09-19 | 2021-06-01 | 莫门蒂夫性能材料股份有限公司 | 用于受控的硅氧烷交联的铂(ii)二烯配合物 |
| US9624233B2 (en) * | 2015-04-23 | 2017-04-18 | Trevi Therapeutics, Inc. | Compounds for treating pruritic conditions |
| CN106478558B (zh) * | 2016-10-17 | 2019-03-29 | 天津雅奥科技发展有限公司 | 一种4-羟甲基-二氢-呋喃-2(3h)-酮的合成方法 |
| US12319686B2 (en) | 2019-01-17 | 2025-06-03 | Hoffmann-La Roche Inc. | Process for the preparation of tetrahydropyridopyrimidines |
| CN114007623A (zh) * | 2019-06-12 | 2022-02-01 | 加利福尼亚大学董事会 | 治疗胆汁酸性腹泻的方法 |
| AU2022265718A1 (en) | 2021-04-29 | 2023-11-02 | Novartis Ag | Deubiquitinase-targeting chimeras and related methods |
| CN117654560B (zh) * | 2023-12-01 | 2024-06-04 | 安徽泽升科技股份有限公司 | 一种通过氧化氨基连续化制备硝基化合物的方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2382528A1 (en) | 1999-08-25 | 2001-03-01 | Banyu Pharmaceutical Co., Ltd. | Novel isoindole derivatives |
| JP2002255967A (ja) | 2001-02-27 | 2002-09-11 | Banyu Pharmaceut Co Ltd | イソインドール誘導体を有効成分とする糖尿病の治療剤、糖尿病の慢性合併症の予防剤又は肥満の治療剤。 |
| JP2007524596A (ja) | 2003-02-28 | 2007-08-30 | トランスフォーム・ファーマシューティカルズ・インコーポレイテッド | 共結晶医薬組成物 |
| MX2009006228A (es) | 2006-12-12 | 2009-06-22 | Schering Corp | Inhibidores de aspartil proteasa. |
| US20110015137A1 (en) * | 2007-07-05 | 2011-01-20 | Trustees Of Boston University | Reca inhibitors and their uses as microbial inhibitors or potentiators of antibiotic activity |
| AU2008345225A1 (en) | 2007-12-21 | 2009-07-09 | University Of Rochester | Method for altering the lifespan of eukaryotic organisms |
| IN2012DN00719A (enExample) * | 2009-08-10 | 2015-06-19 | Univ California | |
| USRE48842E1 (en) * | 2011-05-27 | 2021-12-07 | The Regents Of The University Of California | Pyrimido-pyrrolo-oxazine-dione compound inhibitors of the cystic fibrosis transmembrane conductance regulator protein and uses therefor |
| EP2935278B1 (en) | 2012-12-19 | 2017-03-15 | Novartis AG | Tricyclic compounds for inhibiting the cftr channel |
| KR20150095925A (ko) | 2012-12-19 | 2015-08-21 | 노파르티스 아게 | Cftr 억제제로서의 트리시클릭 화합물 |
-
2013
- 2013-12-17 EP EP13826625.9A patent/EP2935278B1/en active Active
- 2013-12-17 CA CA2895660A patent/CA2895660A1/en not_active Abandoned
- 2013-12-17 BR BR112015014292A patent/BR112015014292A2/pt not_active IP Right Cessation
- 2013-12-17 WO PCT/IB2013/061043 patent/WO2014097148A1/en not_active Ceased
- 2013-12-17 JP JP2015548837A patent/JP6284546B2/ja not_active Expired - Fee Related
- 2013-12-17 KR KR1020157019061A patent/KR20150097660A/ko not_active Withdrawn
- 2013-12-17 AU AU2013365739A patent/AU2013365739A1/en not_active Abandoned
- 2013-12-17 MX MX2015007939A patent/MX2015007939A/es unknown
- 2013-12-17 US US14/653,084 patent/US9359381B2/en active Active
- 2013-12-17 HK HK15110599.7A patent/HK1209741A1/xx unknown
- 2013-12-17 US US14/109,922 patent/US20140171417A1/en not_active Abandoned
- 2013-12-17 PE PE2015001056A patent/PE20151055A1/es not_active Application Discontinuation
- 2013-12-17 EA EA201591177A patent/EA201591177A1/ru unknown
- 2013-12-17 CN CN201380073218.3A patent/CN105143230B/zh not_active Expired - Fee Related
- 2013-12-17 ES ES13826625.9T patent/ES2628369T3/es active Active
- 2013-12-17 AP AP2015008539A patent/AP2015008539A0/xx unknown
- 2013-12-17 SG SG11201504594QA patent/SG11201504594QA/en unknown
- 2013-12-18 TW TW102147023A patent/TW201429974A/zh unknown
- 2013-12-19 AR ARP130104861A patent/AR094122A1/es unknown
- 2013-12-19 UY UY0001035211A patent/UY35211A/es not_active Application Discontinuation
-
2015
- 2015-06-11 IL IL239389A patent/IL239389A0/en unknown
- 2015-06-16 TN TNP2015000279A patent/TN2015000279A1/fr unknown
- 2015-06-17 PH PH12015501386A patent/PH12015501386A1/en unknown
- 2015-06-18 CL CL2015001730A patent/CL2015001730A1/es unknown
- 2015-06-19 CR CR20150325A patent/CR20150325A/es unknown
- 2015-06-19 CU CUP2015000066A patent/CU20150066A7/es unknown
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