JP2016508989A5 - - Google Patents

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Publication number
JP2016508989A5
JP2016508989A5 JP2015552139A JP2015552139A JP2016508989A5 JP 2016508989 A5 JP2016508989 A5 JP 2016508989A5 JP 2015552139 A JP2015552139 A JP 2015552139A JP 2015552139 A JP2015552139 A JP 2015552139A JP 2016508989 A5 JP2016508989 A5 JP 2016508989A5
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JP
Japan
Prior art keywords
suspension
particles
drying
high pressure
homogenization
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2015552139A
Other languages
English (en)
Japanese (ja)
Other versions
JP2016508989A (ja
JP6316847B2 (ja
Filing date
Publication date
Priority claimed from PT106738A external-priority patent/PT106738B/pt
Application filed filed Critical
Publication of JP2016508989A publication Critical patent/JP2016508989A/ja
Publication of JP2016508989A5 publication Critical patent/JP2016508989A5/ja
Application granted granted Critical
Publication of JP6316847B2 publication Critical patent/JP6316847B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2015552139A 2013-01-09 2014-01-09 オストワルド熟成を制御するための動的懸濁乾燥(dsd) Expired - Fee Related JP6316847B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PT106738A PT106738B (pt) 2013-01-09 2013-01-09 Método para o controlo do fenómeno de degradação difusional de ostwald (ostwald ripening) no processamento de partículas de um ingrediente farmacêutico
PT106738 2013-01-09
PCT/GB2014/050055 WO2014108687A1 (en) 2013-01-09 2014-01-09 Dynamic suspension drying (dsd) to control ostwald ripening

Publications (3)

Publication Number Publication Date
JP2016508989A JP2016508989A (ja) 2016-03-24
JP2016508989A5 true JP2016508989A5 (enExample) 2017-02-09
JP6316847B2 JP6316847B2 (ja) 2018-04-25

Family

ID=49999991

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2015552139A Expired - Fee Related JP6316847B2 (ja) 2013-01-09 2014-01-09 オストワルド熟成を制御するための動的懸濁乾燥(dsd)

Country Status (13)

Country Link
US (1) US10151529B2 (enExample)
EP (1) EP2874609B1 (enExample)
JP (1) JP6316847B2 (enExample)
CN (1) CN105007900B (enExample)
BR (1) BR112015016605B1 (enExample)
CA (1) CA2897277C (enExample)
DK (1) DK2874609T3 (enExample)
ES (1) ES2659968T3 (enExample)
HU (1) HUE036691T2 (enExample)
IL (1) IL239845B (enExample)
PT (1) PT106738B (enExample)
SG (1) SG11201505370RA (enExample)
WO (1) WO2014108687A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT108368B (pt) 2015-03-31 2018-11-05 Hovione Farm S A Produção contínua de partículas

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4826689A (en) 1984-05-21 1989-05-02 University Of Rochester Method for making uniformly sized particles from water-insoluble organic compounds
US5997904A (en) * 1993-02-22 1999-12-07 American Bioscience, Inc. Total nutrient admixtures as stable multicomponent liquids or dry powders and methods for the preparation thereof
US5439686A (en) * 1993-02-22 1995-08-08 Vivorx Pharmaceuticals, Inc. Methods for in vivo delivery of substantially water insoluble pharmacologically active agents and compositions useful therefor
US5650156A (en) * 1993-02-22 1997-07-22 Vivorx Pharmaceuticals, Inc. Methods for in vivo delivery of nutriceuticals and compositions useful therefor
DK0693924T4 (da) * 1993-02-22 2008-08-04 Abraxis Bioscience Inc Fremgangsmåde til (in vivo) levering af biologiske materialer og sammensætninger, der er egnede dertil
US5665382A (en) * 1993-02-22 1997-09-09 Vivorx Pharmaceuticals, Inc. Methods for the preparation of pharmaceutically active agents for in vivo delivery
US6749868B1 (en) * 1993-02-22 2004-06-15 American Bioscience, Inc. Protein stabilized pharmacologically active agents, methods for the preparation thereof and methods for the use thereof
US5665383A (en) * 1993-02-22 1997-09-09 Vivorx Pharmaceuticals, Inc. Methods for the preparation of immunostimulating agents for in vivo delivery
US6096331A (en) * 1993-02-22 2000-08-01 Vivorx Pharmaceuticals, Inc. Methods and compositions useful for administration of chemotherapeutic agents
US5916596A (en) * 1993-02-22 1999-06-29 Vivorx Pharmaceuticals, Inc. Protein stabilized pharmacologically active agents, methods for the preparation thereof and methods for the use thereof
CA2684454A1 (en) * 1999-05-21 2000-11-18 American Bioscience, Llc. Protein stabilized pharmacologically active agents, methods for the preparation thereof and methods for the use thereof
US6318649B1 (en) * 1999-10-06 2001-11-20 Cornerstone Technologies, Llc Method of creating ultra-fine particles of materials using a high-pressure mill
EP1276465B1 (en) 2000-04-20 2014-03-12 Jagotec AG Improved water-insoluble drug particle process
WO2002004125A2 (en) * 2000-07-06 2002-01-17 Cornerstone Technologies, L.L.C. Multi-stage size reduction, blending and drying system and method
KR100914113B1 (ko) * 2001-08-06 2009-08-27 아스트라제네카 아베 수불용성이고 활성인 안정한 나노입자 및 중쇄트리글리세리드(mct)와 같은 부형제를 포함하는수분산액
WO2004052567A2 (en) * 2002-12-06 2004-06-24 Cornerstone Technologies, L.L.C. High g mill in a blending and drying system
US8728527B2 (en) * 2006-07-24 2014-05-20 Luminus Biosciences, Inc. Solid nanoparticle formulation of water insoluble pharmaceutical substances with reduced ostwald ripening
PT105058B (pt) 2010-04-21 2013-04-17 Hovione Farmaciencia S A Processo para processamento de partículas de ingredientes activos farmacêuticos

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