JP2016507723A - 結腸腫瘍の存在またはリスクの評価方法 - Google Patents

結腸腫瘍の存在またはリスクの評価方法 Download PDF

Info

Publication number
JP2016507723A
JP2016507723A JP2015545504A JP2015545504A JP2016507723A JP 2016507723 A JP2016507723 A JP 2016507723A JP 2015545504 A JP2015545504 A JP 2015545504A JP 2015545504 A JP2015545504 A JP 2015545504A JP 2016507723 A JP2016507723 A JP 2016507723A
Authority
JP
Japan
Prior art keywords
proteins
subject
analysis
amount
pkm2
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2015545504A
Other languages
English (en)
Japanese (ja)
Other versions
JP2016507723A5 (OSRAM
Inventor
ブルーム,ジョン
ベンツ,ライアン
クロナー,リサ
ディ
ディロン,ロズリン
ランドール,アルロ
ジョーンズ,ジェフリー
スコア,ヘザー
ストックフィッシュ,トム
ウィルコックス,ブルース
ルダーマン,ダニエル
Original Assignee
アプライド・プロテオミクス,インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by アプライド・プロテオミクス,インコーポレイテッド filed Critical アプライド・プロテオミクス,インコーポレイテッド
Publication of JP2016507723A publication Critical patent/JP2016507723A/ja
Publication of JP2016507723A5 publication Critical patent/JP2016507723A5/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407Specifically defined cancers
    • G01N33/57419Specifically defined cancers of colon
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/20Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/20Supervised data analysis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/60Complex ways of combining multiple protein biomarkers for diagnosis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/70Mechanisms involved in disease identification
    • G01N2800/7023(Hyper)proliferation
    • G01N2800/7028Cancer
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Medical Informatics (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Evolutionary Biology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Theoretical Computer Science (AREA)
  • Biophysics (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Data Mining & Analysis (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Artificial Intelligence (AREA)
  • Bioethics (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Databases & Information Systems (AREA)
  • Epidemiology (AREA)
  • Evolutionary Computation (AREA)
  • Public Health (AREA)
  • Software Systems (AREA)
JP2015545504A 2012-11-30 2013-12-02 結腸腫瘍の存在またはリスクの評価方法 Pending JP2016507723A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261732024P 2012-11-30 2012-11-30
US61/732,024 2012-11-30
US201361772979P 2013-03-05 2013-03-05
US61/772,979 2013-03-05
PCT/US2013/072691 WO2014085826A2 (en) 2012-11-30 2013-12-02 Method for evaluation of presence of or risk of colon tumors

Publications (2)

Publication Number Publication Date
JP2016507723A true JP2016507723A (ja) 2016-03-10
JP2016507723A5 JP2016507723A5 (OSRAM) 2017-01-19

Family

ID=50828610

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2015545504A Pending JP2016507723A (ja) 2012-11-30 2013-12-02 結腸腫瘍の存在またはリスクの評価方法

Country Status (11)

Country Link
US (6) US20140234854A1 (OSRAM)
EP (1) EP2926138A4 (OSRAM)
JP (1) JP2016507723A (OSRAM)
KR (1) KR20150090240A (OSRAM)
CN (2) CN110596385A (OSRAM)
AU (1) AU2013351947A1 (OSRAM)
BR (1) BR112015012616A2 (OSRAM)
CA (1) CA2893158A1 (OSRAM)
MX (1) MX2015006757A (OSRAM)
SG (1) SG11201504241QA (OSRAM)
WO (1) WO2014085826A2 (OSRAM)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017198509A (ja) * 2016-04-26 2017-11-02 学校法人近畿大学 大腸癌マーカー
JP2020500293A (ja) * 2016-10-07 2020-01-09 ディサーンディーエックス,インク. 大腸癌及び進行性腺腫を検知するためのタンパク質バイオマーカーパネル
JP2022531058A (ja) * 2019-03-06 2022-07-06 ディアデム エス.アール.エル. アルツハイマー病の診断と予後判定におけるマーカーとしてのp53ペプチド

Families Citing this family (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9141756B1 (en) 2010-07-20 2015-09-22 University Of Southern California Multi-scale complex systems transdisciplinary analysis of response to therapy
CN108802385B (zh) 2012-02-09 2022-02-08 米密德诊断学有限公司 用于诊断感染的标记和决定因素和其使用方法
AU2015237229A1 (en) * 2014-03-28 2016-11-10 Applied Proteomics, Inc. Protein biomarker profiles for detecting colorectal tumors
KR20190080973A (ko) * 2014-07-11 2019-07-08 익스프레션 패톨로지, 인크. GTPase KRas 단백질(KRas)에 대한 SRM/MRM 검정
CA3190715A1 (en) 2014-08-14 2016-02-18 Memed Diagnostics Ltd. Computational analysis of biological data using manifold and a hyperplane
EP3189457A4 (en) * 2014-09-05 2018-04-11 Nantomics, LLC Systems and methods for determination of provenance
WO2016092554A1 (en) 2014-12-11 2016-06-16 Memed Diagnostics Ltd. Marker combinations for diagnosing infections and methods of use thereof
AU2015360420B2 (en) * 2014-12-11 2021-12-09 Wisconsin Alumni Research Foundation Methods for detection and treatment of colorectal cancer
CN105807062A (zh) * 2014-12-28 2016-07-27 复旦大学 人结肠癌蛋白Spondin-2在制备结肠癌诊断制剂中的应用
CN105385752A (zh) * 2015-03-23 2016-03-09 复旦大学 一种人结肠癌蛋白质标志物Spondin-2的检测方法及其检测试剂盒
EP3281016A1 (en) 2015-04-10 2018-02-14 Applied Proteomics Inc. Protein biomarker panels for detecting colorectal cancer and advanced adenoma
EP3974539A1 (en) * 2015-07-01 2022-03-30 Duke University Methods to diagnose and treat acute respiratory infections
EP3371605B1 (en) * 2015-11-05 2021-06-23 Vanderbilt University Protein quantitation in multicellular tissue specimens
US11466331B2 (en) 2016-03-03 2022-10-11 Memed Diagnostics Ltd. RNA determinants for distinguishing between bacterial and viral infections
WO2017180652A1 (en) * 2016-04-11 2017-10-19 Applied Proteomics, Inc. Mass spectrometric data analysis workflow
CN107345236A (zh) * 2016-05-04 2017-11-14 北京美泽福临科技发展有限公司 一种amy2b信使rna的特异性扩增引物和肝癌辅助诊断试剂盒
EP3469369A1 (en) * 2016-06-10 2019-04-17 Wisconsin Alumni Research Foundation Methods for detection, staging, and surveillance of colorectal adenomas and carcinomas
CN109661578B (zh) 2016-07-10 2022-05-10 米密德诊断学有限公司 用于区分细菌和病毒感染的蛋白质特征
WO2018011796A1 (en) 2016-07-10 2018-01-18 Memed Diagnostics Ltd. Early diagnosis of infections
CN106202984B (zh) * 2016-08-26 2018-09-04 赵毅 一种基于多层复杂网络对肿瘤miRNA标志物的筛选方法
EP3519833B1 (en) 2016-09-29 2024-08-14 MeMed Diagnostics Ltd. Methods of prognosis and treatment
EP3519834A4 (en) * 2016-09-29 2020-06-17 MeMed Diagnostics Ltd. RISK ASSESSMENT AND DISEASE CLASSIFICATION METHODS
JP6813033B2 (ja) * 2017-01-19 2021-01-13 株式会社島津製作所 分析データ解析方法および分析データ解析装置
US11204355B2 (en) 2017-02-20 2021-12-21 Vanderbilt University Immune checkpoint molecular fitness profiling by mass spectrometry
CN106919801B (zh) * 2017-03-08 2023-07-18 杭州大伽信息科技有限公司 一种免疫组织化学染色辅助分析系统及使用方法
CN106908608B (zh) * 2017-04-17 2018-10-02 首都医科大学附属北京胸科医院 辅助诊断重症继发性肺结核的蛋白标志物
US20180330059A1 (en) * 2017-05-09 2018-11-15 James Stewart Bates Patient treatment systems and methods
US10455457B2 (en) 2017-05-24 2019-10-22 Qualcomm Incorporated NR-SS unified operation mode in coordinated and uncoordinated bands
US11164679B2 (en) 2017-06-20 2021-11-02 Advinow, Inc. Systems and methods for intelligent patient interface exam station
AU2018293090A1 (en) * 2017-06-30 2020-02-13 Denka Company Limited Biomarker for detecting colorectal cancer
AU2018301704A1 (en) * 2017-07-14 2020-03-05 Cofactor Genomics, Inc. Immuno-oncology applications using next generation sequencing
CN109406785A (zh) 2017-08-18 2019-03-01 山东泽济生物科技有限公司 肿瘤血液标志物及其应用
WO2019113239A1 (en) * 2017-12-05 2019-06-13 Discerndx, Inc. Robust panels of colorectal cancer biomarkers
US20190383832A1 (en) * 2017-12-29 2019-12-19 Abbott Laboratories Novel biomarkers and methods for diagnosing and evaluating traumatic brain injury
US11414707B2 (en) 2018-01-22 2022-08-16 Liquid Biopsy Research LLC Methods for colon cancer detection and treatment
US11348688B2 (en) 2018-03-06 2022-05-31 Advinow, Inc. Systems and methods for audio medical instrument patient measurements
EP3776381A4 (en) 2018-04-13 2022-01-05 Freenome Holdings, Inc. IMPLEMENTATION OF MACHINE LEARNING FOR MULTI-ANALYTE TESTS OF BIOLOGICAL SAMPLES
WO2020010256A1 (en) * 2018-07-05 2020-01-09 Edp Biotech Corporation Kits and methods for detecting markers
CN112888793A (zh) 2018-08-08 2021-06-01 里珍纳龙药品有限公司 使用lc-ms/ms对蛋白质生物标志物进行定量
EP3623813A1 (en) * 2018-09-17 2020-03-18 Institut d'Investigació Sanitària Pere Virgili Methods for the prognosis of hiv-infected subjects
US12499537B2 (en) * 2019-11-13 2025-12-16 University Of South Florida Systems and methods of deep learning for colorectal polyp screening
CN110951707B (zh) * 2019-12-31 2022-11-11 南京医科大学 丙酮酸激酶m2突变体及其在心血管疾病中的应用
CN115616230A (zh) * 2020-03-18 2023-01-17 龙海市第一医院 用于肝癌早期诊断的检测岩藻糖基化载脂蛋白h的elisa试剂盒
WO2022006628A1 (en) * 2020-07-08 2022-01-13 Southern Adelaide Local Health Network Inc. Computer-implemented method and system for identifying measurable features for use in a predictive model
CN112194719A (zh) * 2020-09-01 2021-01-08 中日友好医院(中日友好临床医学研究所) Crt抗原和mage-a1抗原的制备及其应用
CN112034182A (zh) * 2020-09-01 2020-12-04 复旦大学附属中山医院 一种结肠癌转移预测方法和系统
CN112266961B (zh) * 2020-10-29 2023-05-12 中山大学附属第六医院 Tsg-6基因在预测结直肠癌转移及预后方面的应用
CN112710856B (zh) * 2020-12-16 2022-12-02 江西省肿瘤医院(江西省癌症中心) 检测血清igf1蛋白的制剂在制备结直肠癌疗效监测试剂中的应用
CN113447658B (zh) * 2021-07-01 2022-04-19 浙江大学 一种检测抗过氧化物还原酶-1-IgG抗体的试剂盒
CN113956327B (zh) * 2021-10-11 2024-01-30 中山大学肿瘤防治中心 靶向人apc蛋白的多肽及其在制备药物中的应用
WO2023183481A1 (en) * 2022-03-23 2023-09-28 Serum Detect, Inc. Biomarker signatures indicative of early stages of cancer
CN114445406B (zh) * 2022-04-07 2022-08-09 武汉大学 肠镜图像分析方法、装置和医学图像处理设备
TWI796228B (zh) 2022-05-25 2023-03-11 臺中榮民總醫院 急性腎損傷預測系統及其方法
CN114668836B (zh) * 2022-05-27 2022-08-19 暨南大学 Pdia6在制备治疗脊髓损伤和修复的药物中的应用
CN114958794B (zh) * 2022-06-14 2023-06-02 南京工业大学 一种苯乙醇胺-N-甲基转移酶hPNMT54及其克隆表达与应用
CN116593431B (zh) * 2023-04-09 2025-11-07 湖南科技大学三亚研究院 一种基于亲和传感器法的米酵菌酸毒素便携式检测装置及检测方法
US20240379228A1 (en) * 2023-05-08 2024-11-14 Venn Biosciences Corporation Diagnosis of colorectal cancer using targeted quantification of peptides
WO2025058445A1 (ko) * 2023-09-15 2025-03-20 연세대학교 산학협력단 대장암에 대한 정보 제공 방법
CN118067993B (zh) * 2024-04-17 2024-07-05 弗雷米德生物医药技术(天津)有限公司 一种用于肠息肉检测的联检试剂盒及其制备方法、检测方法和应用
CN118496322A (zh) * 2024-05-09 2024-08-16 昆明医科大学 一种靶向降解β-catenin的多肽型抑制剂及其应用

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003065003A2 (en) * 2002-01-25 2003-08-07 University Of Pittsburgh Nuclear matrix protein alterations associated with colon cancer and colon metastasis to the liver, and uses thereof
WO2006053592A1 (en) * 2004-08-13 2006-05-26 Indivumed Gmbh Use of c3a and derivatives thereof as a biomarker for colorectal ademona and/or carcinoma; diagnosis method and test system using the same
US20080145852A1 (en) * 2005-03-01 2008-06-19 Shuber Anthony P Methods and compositions for detecting adenoma
JP2010533853A (ja) * 2007-07-19 2010-10-28 ビオメリュー 結腸直腸癌のインビトロ診断のための肝臓脂肪酸結合タンパク質、ceaおよびca19−9のアッセイのための方法
US20100304410A1 (en) * 2007-09-28 2010-12-02 Royal College Of Surgeons In Ireland Method of assessing colorectal cancer status in an individual
JP2010281836A (ja) * 2004-02-19 2010-12-16 Yale Univ プロテオーム技術を使用した癌タンパク質バイオマーカーの同定
JP2011506917A (ja) * 2007-12-10 2011-03-03 エフ.ホフマン−ラ ロシュ アーゲー 結腸直腸癌のためのマーカーパネル

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4444879A (en) * 1981-01-29 1984-04-24 Science Research Center, Inc. Immunoassay with article having support film and immunological counterpart of analyte
US4517289A (en) * 1982-08-18 1985-05-14 Brigham And Women's Hospital Monoclonal antibodies for human tissue cross-matching
US5736343A (en) * 1995-08-18 1998-04-07 Landry; Donald Detection of organic compounds through regulation of antibody-catalyzed reactions
US5800347A (en) * 1995-11-03 1998-09-01 The General Hospital Corporation ROC method for early detection of disease
NO954667D0 (no) * 1995-11-17 1995-11-17 Dagfinn Oegreid Fremgangsmåte til deteksjon av Ki-ras mutasjoner
AU767833B2 (en) * 1999-01-10 2003-11-27 Exact Sciences Corporation Methods of detecting colorectal disease
US20010041365A1 (en) * 2000-01-10 2001-11-15 Michael Laposata Methods for monitoring alcohol consumption
US20050153382A1 (en) * 2002-06-06 2005-07-14 Chengdu Kuachang Science And Technology Co., Ltd. Biochip kit comprising biochip based on antigen-antibody reactions, and its usage
US20060105419A1 (en) * 2004-08-16 2006-05-18 Biosite, Inc. Use of a glutathione peroxidase 1 as a marker in cardiovascular conditions
CN101283280A (zh) * 2005-08-18 2008-10-08 Zadec私人有限公司 用于诊断结直肠癌的蛋白质标记和所述标记作为所述癌症类型治疗的药物靶点的用途
WO2007141595A2 (en) * 2005-11-10 2007-12-13 Aurelium Biopharma Inc. Method of diagnosing breast cancer using protein markers
EP2223115B1 (en) * 2007-12-10 2011-09-14 Roche Diagnostics GmbH Seprase as a marker for cancer
CA2715170A1 (en) * 2008-02-11 2009-08-20 Hadasit Medical Research Services & Development Limited Colon cancer associated transcript 1 (ccat-1) as a cancer marker
US20110076700A1 (en) * 2008-02-29 2011-03-31 Nihon University Anti-crp antibody and utilization of the same
US20110245087A1 (en) * 2008-03-18 2011-10-06 Gunter Weiss Method for optimizing and validating an assay for determining the presence or absence of a medical condition
US20110065605A1 (en) * 2008-05-14 2011-03-17 Eth Zurich Method for biomarker and drug-target discovery for prostate cancer diagnosis and treatment as well as biomarker assays determined therewith
ES2506116T3 (es) * 2008-05-23 2014-10-13 Biocartis Nv Nuevo biomarcador para diagnóstico, predicción y/o pronóstico de septicemia y usos del mismo
KR20120105444A (ko) * 2009-10-15 2012-09-25 오클라호마 메디컬 리써치 화운데이션 염증성 질병의 활성 측정 및 모니터링을 위한 바이오마커 및 방법
US10119959B2 (en) * 2010-06-25 2018-11-06 The Board Of Trustees Of The Leland Stanford Junior University Method of assaying an individual for immune impairment
WO2012101283A1 (en) * 2011-01-28 2012-08-02 Biosystems International Sas Combinatorial biomarkers for clinical applications in lung cancer patient management
AU2012220872A1 (en) * 2011-02-22 2013-09-12 Caris Life Sciences Switzerland Holdings Gmbh Circulating biomarkers
CA2845568A1 (en) * 2011-08-19 2013-02-28 Myriad Genetics, Inc. Gene signatures for lung cancer prognosis and therapy selection

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003065003A2 (en) * 2002-01-25 2003-08-07 University Of Pittsburgh Nuclear matrix protein alterations associated with colon cancer and colon metastasis to the liver, and uses thereof
JP2010281836A (ja) * 2004-02-19 2010-12-16 Yale Univ プロテオーム技術を使用した癌タンパク質バイオマーカーの同定
WO2006053592A1 (en) * 2004-08-13 2006-05-26 Indivumed Gmbh Use of c3a and derivatives thereof as a biomarker for colorectal ademona and/or carcinoma; diagnosis method and test system using the same
US20080145852A1 (en) * 2005-03-01 2008-06-19 Shuber Anthony P Methods and compositions for detecting adenoma
JP2010533853A (ja) * 2007-07-19 2010-10-28 ビオメリュー 結腸直腸癌のインビトロ診断のための肝臓脂肪酸結合タンパク質、ceaおよびca19−9のアッセイのための方法
US20100304410A1 (en) * 2007-09-28 2010-12-02 Royal College Of Surgeons In Ireland Method of assessing colorectal cancer status in an individual
JP2011506917A (ja) * 2007-12-10 2011-03-03 エフ.ホフマン−ラ ロシュ アーゲー 結腸直腸癌のためのマーカーパネル

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017198509A (ja) * 2016-04-26 2017-11-02 学校法人近畿大学 大腸癌マーカー
JP2020500293A (ja) * 2016-10-07 2020-01-09 ディサーンディーエックス,インク. 大腸癌及び進行性腺腫を検知するためのタンパク質バイオマーカーパネル
JP2022531058A (ja) * 2019-03-06 2022-07-06 ディアデム エス.アール.エル. アルツハイマー病の診断と予後判定におけるマーカーとしてのp53ペプチド
JP7539399B2 (ja) 2019-03-06 2024-08-23 ディアデム エス.アール.エル. アルツハイマー病の診断と予後判定におけるマーカーとしてのp53ペプチド

Also Published As

Publication number Publication date
EP2926138A2 (en) 2015-10-07
US20150111223A1 (en) 2015-04-23
US20150111221A1 (en) 2015-04-23
KR20150090240A (ko) 2015-08-05
AU2013351947A1 (en) 2015-06-18
CN110596385A (zh) 2019-12-20
US20170285033A1 (en) 2017-10-05
CA2893158A1 (en) 2014-06-05
CN104969071A (zh) 2015-10-07
US20150111230A1 (en) 2015-04-23
WO2014085826A3 (en) 2014-10-23
CN104969071B (zh) 2019-09-03
US20140234854A1 (en) 2014-08-21
SG11201504241QA (en) 2015-06-29
BR112015012616A2 (pt) 2017-09-12
US20150111220A1 (en) 2015-04-23
WO2014085826A2 (en) 2014-06-05
MX2015006757A (es) 2015-11-30
EP2926138A4 (en) 2016-09-14

Similar Documents

Publication Publication Date Title
CN104969071B (zh) 用于评估结肠肿瘤的存在或风险的方法
US11041866B2 (en) Pancreatic cancer biomarkers and uses thereof
JP6105491B2 (ja) 照合性細胞ベースのアッセイ及びその使用
EP3029153B1 (en) Mesothelioma biomarkers and uses thereof
US9689874B2 (en) Protein biomarker panels for detecting colorectal cancer and advanced adenoma
US20170176441A1 (en) Protein biomarker profiles for detecting colorectal tumors
WO2008064336A2 (en) Autoimmune disease biomarkers
HK1248316A1 (en) Methods of assessing colorectal health of an individual
WO2018068020A1 (en) Protein biomarker panels for detecting colorectal cancer and advanced adenoma
US20240393337A1 (en) Lung Cancer Prediction and Uses Thereof
KR20240004546A (ko) 결장직장암에 대한 바이오마커
US20230048910A1 (en) Methods of Determining Impaired Glucose Tolerance

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20161201

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20161201

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20170908

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20171003

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20171218

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20180529