JP2016507526A5 - - Google Patents
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- Publication number
- JP2016507526A5 JP2016507526A5 JP2015556185A JP2015556185A JP2016507526A5 JP 2016507526 A5 JP2016507526 A5 JP 2016507526A5 JP 2015556185 A JP2015556185 A JP 2015556185A JP 2015556185 A JP2015556185 A JP 2015556185A JP 2016507526 A5 JP2016507526 A5 JP 2016507526A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- sulfasalazine
- composition according
- polymer
- pvp
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 13
- UETNIIAIRMUTSM-UHFFFAOYSA-N Jacareubin Natural products CC1(C)OC2=CC3Oc4c(O)c(O)ccc4C(=O)C3C(=C2C=C1)O UETNIIAIRMUTSM-UHFFFAOYSA-N 0.000 claims 11
- NCEXYHBECQHGNR-QZQOTICOSA-N sulfasalazine Chemical compound C1=C(O)C(C(=O)O)=CC(\N=N\C=2C=CC(=CC=2)S(=O)(=O)NC=2N=CC=CC=2)=C1 NCEXYHBECQHGNR-QZQOTICOSA-N 0.000 claims 11
- 229960001940 sulfasalazine Drugs 0.000 claims 11
- NCEXYHBECQHGNR-UHFFFAOYSA-N sulfasalazine Natural products C1=C(O)C(C(=O)O)=CC(N=NC=2C=CC(=CC=2)S(=O)(=O)NC=2N=CC=CC=2)=C1 NCEXYHBECQHGNR-UHFFFAOYSA-N 0.000 claims 11
- 208000015122 neurodegenerative disease Diseases 0.000 claims 8
- 229920000642 polymer Polymers 0.000 claims 7
- 238000000034 method Methods 0.000 claims 6
- 229920003083 Kollidon® VA64 Polymers 0.000 claims 4
- 206010053395 Progressive multiple sclerosis Diseases 0.000 claims 4
- 206010002026 amyotrophic lateral sclerosis Diseases 0.000 claims 4
- 238000000338 in vitro Methods 0.000 claims 4
- 230000004770 neurodegeneration Effects 0.000 claims 4
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 238000010922 spray-dried dispersion Methods 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361759933P | 2013-02-01 | 2013-02-01 | |
| US61/759,933 | 2013-02-01 | ||
| US201361780340P | 2013-03-13 | 2013-03-13 | |
| US61/780,340 | 2013-03-13 | ||
| PCT/US2014/014290 WO2014121137A2 (en) | 2013-02-01 | 2014-01-31 | Compositions and methods for the treatment of neurodegenerative and other diseases |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018079284A Division JP2018123159A (ja) | 2013-02-01 | 2018-04-17 | 神経変性およびその他の疾患の治療用組成物および方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016507526A JP2016507526A (ja) | 2016-03-10 |
| JP2016507526A5 true JP2016507526A5 (OSRAM) | 2017-02-23 |
| JP6328146B2 JP6328146B2 (ja) | 2018-05-23 |
Family
ID=50382538
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015556185A Expired - Fee Related JP6328146B2 (ja) | 2013-02-01 | 2014-01-31 | 神経変性およびその他の疾患の治療用組成物および方法 |
| JP2018079284A Pending JP2018123159A (ja) | 2013-02-01 | 2018-04-17 | 神経変性およびその他の疾患の治療用組成物および方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018079284A Pending JP2018123159A (ja) | 2013-02-01 | 2018-04-17 | 神経変性およびその他の疾患の治療用組成物および方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (5) | US9597339B2 (OSRAM) |
| EP (1) | EP2950797B1 (OSRAM) |
| JP (2) | JP6328146B2 (OSRAM) |
| KR (1) | KR20150139830A (OSRAM) |
| CN (1) | CN105163735B (OSRAM) |
| AU (2) | AU2014212109B2 (OSRAM) |
| CA (1) | CA2899032A1 (OSRAM) |
| ES (1) | ES2752021T3 (OSRAM) |
| IL (1) | IL240206A0 (OSRAM) |
| WO (1) | WO2014121137A2 (OSRAM) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6328146B2 (ja) * | 2013-02-01 | 2018-05-23 | グリアロジクス・インコーポレイテッドＧｌｉａｌｏｇｉｘ， Ｉｎｃ． | 神経変性およびその他の疾患の治療用組成物および方法 |
| KR102364840B1 (ko) | 2014-11-05 | 2022-02-18 | 삼성전자주식회사 | 신경세포의 탈수초화와 연관된 질환을 치료하기 위한 약학적 조성물 및 그를 이용하는 방법 |
| US20160199393A1 (en) * | 2015-01-08 | 2016-07-14 | China Medical University | Methods of treating brain ischemia or hypoxia |
| ES2650175B1 (es) * | 2016-04-15 | 2019-02-04 | Servicio Andaluz De Salud | Tratamiento de enfermedades neurodegenerativas |
| WO2017189504A1 (en) * | 2016-04-26 | 2017-11-02 | Saint Louis University | Highly selective adenosine a3 receptor subtype agonsists for the prevention and treatment of neurodegenerative disorders |
| TW201818933A (zh) * | 2016-10-21 | 2018-06-01 | 美商吉利亞洛吉克斯公司 | 用於神經退化性及其他疾病的治療之組成物和方法 |
| US10473672B2 (en) * | 2017-02-09 | 2019-11-12 | Kaohsiung Chang Gung Memorial Hospital | Methods for diagnosing and treating Alzheimers disease using G72 protein and SLC7A11 mRNA as biomarkers |
| US20230210871A1 (en) * | 2017-10-12 | 2023-07-06 | The Limited Company Research And Development Company "Medbiopharm" | Use of sulfasalazine as an inhibitor of the formation of advanced glycation end products |
| WO2019102992A1 (ja) * | 2017-11-21 | 2019-05-31 | 積水化学工業株式会社 | 皮膚外用剤 |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2396145A (en) | 1940-12-14 | 1946-03-05 | Pharmscia Ab | Heterocyclic sulphonamido azo compounds |
| FR2608988B1 (fr) | 1986-12-31 | 1991-01-11 | Centre Nat Rech Scient | Procede de preparation de systemes colloidaux dispersibles d'une substance, sous forme de nanoparticules |
| JPH10506406A (ja) | 1994-09-29 | 1998-06-23 | アンダリス、リミテッド | 治療用ビヒクルとしての噴霧乾燥させた微細粒子 |
| US5874064A (en) | 1996-05-24 | 1999-02-23 | Massachusetts Institute Of Technology | Aerodynamically light particles for pulmonary drug delivery |
| ITMI962356A1 (it) | 1996-11-13 | 1998-05-13 | Uni Degli Studi Di Brescia D I | Uso di composti derivati da molecole ad attivita' antinfiammatoria di tipo non steroideo per la prevenzione e il trattamento di |
| ES2236832T3 (es) | 1997-01-16 | 2005-07-16 | Massachusetts Institute Of Technology | Preparacion de particulas para inhalacion. |
| JP2002518432A (ja) | 1998-06-24 | 2002-06-25 | アドバンスト インハレーション リサーチ，インコーポレイテッド | 吸入器から放出される大多孔性粒子 |
| DK1107743T3 (da) | 1998-08-25 | 2007-10-22 | Advanced Inhalation Res Inc | Stabile, spraytörrede proteinformuleringer |
| US6586008B1 (en) | 1999-08-25 | 2003-07-01 | Advanced Inhalation Research, Inc. | Use of simple amino acids to form porous particles during spray drying |
| KR100417623B1 (ko) | 2000-03-28 | 2004-02-05 | 주식회사 뉴로테크 | 뇌질환 예방 및 치료용 조성물 |
| CA2307278A1 (en) | 2000-04-28 | 2001-10-28 | University Of British Columbia | Use of n-heterocyclic substituted salicylic acids for inhibition of cellular uptake of cystine |
| BR0307515A (pt) | 2002-02-01 | 2004-12-07 | Pfizer Prod Inc | Método para fabricar dispersões de drogas amorfas sólidas secas por aspersão homogêneas usando bicos de pressão |
| JP4865989B2 (ja) | 2002-02-01 | 2012-02-01 | ベンド・リサーチ・インコーポレーテッド | 改良された噴霧乾燥装置を使用する均質な噴霧乾燥された固体の非晶質薬物分散物を製造する方法 |
| CL2004001884A1 (es) | 2003-08-04 | 2005-06-03 | Pfizer Prod Inc | Procedimiento de secado por pulverizacion para la formacion de dispersiones solidas amorfas de un farmaco y polimeros. |
| US20060045865A1 (en) | 2004-08-27 | 2006-03-02 | Spherics, Inc. | Controlled regional oral delivery |
| US8748445B2 (en) | 2004-10-27 | 2014-06-10 | The Uab Research Foundation | Methods for treating glioma |
| CN101291658B (zh) | 2005-08-31 | 2014-04-16 | 阿布拉科斯生物科学有限公司 | 用于制备稳定性增加的水难溶性药物的组合物和方法 |
| US20070053869A1 (en) | 2005-09-02 | 2007-03-08 | Yuichi Sugiyama | Formulation and method for enhancement of gastrointestinal absorption of pharmaceutical agents |
| GB0602123D0 (en) * | 2006-02-02 | 2006-03-15 | Novartis Ag | Organic compounds |
| PT1983984T (pt) | 2006-02-02 | 2018-06-14 | Novartis Ag | Tratamento da esclerosa tuberosa |
| US7964585B2 (en) | 2006-03-14 | 2011-06-21 | Case Western Reserve University | Composition and method of treating peripheral neuropathy |
| BRPI0716196A2 (pt) | 2006-08-31 | 2013-11-12 | Eurand Inc | Sistemas de distribuição de fármacos que compreendem soluções sólidas de fármacos fracamente básicos. |
| WO2008135828A2 (en) | 2007-05-03 | 2008-11-13 | Pfizer Products Inc. | Nanoparticles comprising a drug, ethylcellulose, and a bile salt |
| WO2009073215A1 (en) | 2007-12-06 | 2009-06-11 | Bend Research, Inc. | Pharmaceutical compositions comprising nanoparticles and a resuspending material |
| BRPI0908340A2 (pt) * | 2008-02-28 | 2018-12-26 | Bial Portela & Ca Sa | composição farmacêutica para fármacos pouco solúveis |
| PT2113254E (pt) * | 2008-04-28 | 2012-11-26 | Txcell | Composições para o tratamento de um estado inflamatório auto-imune |
| TW201438738A (zh) | 2008-09-16 | 2014-10-16 | 建南德克公司 | 治療進展型多發性硬化症之方法 |
| EP2411137B1 (en) | 2009-03-27 | 2016-09-07 | Bend Research, Inc. | Spray-drying process |
| PT2611530T (pt) | 2010-09-03 | 2019-05-09 | Bend Res Inc | Aparelho de secagem por pulverização e métodos de utilização do mesmo |
| WO2012031129A2 (en) | 2010-09-03 | 2012-03-08 | Bend Research, Inc. | Spray-drying apparatus and methods of using the same |
| HK1204970A1 (en) | 2012-01-31 | 2015-12-11 | Cerulean Pharma Inc. | Polymer-agent conjugates, particles, compositions, and related methods of use |
| JP6328146B2 (ja) * | 2013-02-01 | 2018-05-23 | グリアロジクス・インコーポレイテッドＧｌｉａｌｏｇｉｘ， Ｉｎｃ． | 神経変性およびその他の疾患の治療用組成物および方法 |
| ES3041833T3 (en) | 2013-12-31 | 2025-11-14 | Ascendia Pharmaceuticals Llc | Pharmaceutical compositions for poorly water-soluble compounds |
-
2014
- 2014-01-31 JP JP2015556185A patent/JP6328146B2/ja not_active Expired - Fee Related
- 2014-01-31 EP EP14712798.9A patent/EP2950797B1/en active Active
- 2014-01-31 CA CA2899032A patent/CA2899032A1/en not_active Abandoned
- 2014-01-31 ES ES14712798T patent/ES2752021T3/es active Active
- 2014-01-31 AU AU2014212109A patent/AU2014212109B2/en not_active Ceased
- 2014-01-31 CN CN201480019892.8A patent/CN105163735B/zh not_active Expired - Fee Related
- 2014-01-31 US US14/170,405 patent/US9597339B2/en not_active Expired - Fee Related
- 2014-01-31 KR KR1020157023718A patent/KR20150139830A/ko not_active Withdrawn
- 2014-01-31 WO PCT/US2014/014290 patent/WO2014121137A2/en not_active Ceased
-
2015
- 2015-07-29 IL IL240206A patent/IL240206A0/en unknown
-
2016
- 2016-11-30 US US15/365,843 patent/US9980978B2/en not_active Expired - Fee Related
- 2016-11-30 US US15/365,835 patent/US9974798B2/en not_active Expired - Fee Related
-
2017
- 2017-02-10 US US15/430,294 patent/US9918997B2/en not_active Expired - Fee Related
-
2018
- 2018-04-17 JP JP2018079284A patent/JP2018123159A/ja active Pending
- 2018-04-17 US US15/955,020 patent/US10398713B2/en not_active Expired - Fee Related
- 2018-08-28 AU AU2018222921A patent/AU2018222921A1/en not_active Abandoned
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