|
US4593089A
(en)
|
1980-07-30 |
1986-06-03 |
Abbott Laboratories |
Fluorescent polarization immunoassay utilizing substituted triazinylaminofluorescein aminoglycosides
|
|
US4554101A
(en)
|
1981-01-09 |
1985-11-19 |
New York Blood Center, Inc. |
Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity
|
|
GB8308235D0
(en)
|
1983-03-25 |
1983-05-05 |
Celltech Ltd |
Polypeptides
|
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
US5807715A
(en)
|
1984-08-27 |
1998-09-15 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin
|
|
US4751190A
(en)
|
1985-07-22 |
1988-06-14 |
Abbott Laboratories |
Fluorescence polarization immunoassay and reagents for use therein
|
|
US4676980A
(en)
|
1985-09-23 |
1987-06-30 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Target specific cross-linked heteroantibodies
|
|
US5618920A
(en)
|
1985-11-01 |
1997-04-08 |
Xoma Corporation |
Modular assembly of antibody genes, antibodies prepared thereby and use
|
|
US5225539A
(en)
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
|
ATE82588T1
(de)
|
1986-04-28 |
1992-12-15 |
Endotronics Inc |
Zuchtverfahren fuer leukocyten.
|
|
US5260203A
(en)
|
1986-09-02 |
1993-11-09 |
Enzon, Inc. |
Single polypeptide chain binding molecules
|
|
US4946778A
(en)
|
1987-09-21 |
1990-08-07 |
Genex Corporation |
Single polypeptide chain binding molecules
|
|
EP0368684B2
(en)
|
1988-11-11 |
2004-09-29 |
Medical Research Council |
Cloning immunoglobulin variable domain sequences.
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
US6291158B1
(en)
|
1989-05-16 |
2001-09-18 |
Scripps Research Institute |
Method for tapping the immunological repertoire
|
|
US5859205A
(en)
|
1989-12-21 |
1999-01-12 |
Celltech Limited |
Humanised antibodies
|
|
WO1994004679A1
(en)
|
1991-06-14 |
1994-03-03 |
Genentech, Inc. |
Method for making humanized antibodies
|
|
ES2136092T3
(es)
|
1991-09-23 |
1999-11-16 |
Medical Res Council |
Procedimientos para la produccion de anticuerpos humanizados.
|
|
ES2341666T3
(es)
|
1991-12-02 |
2010-06-24 |
Medimmune Limited |
Produccion de autoanticuerpos de repertorios de segmentos de anticue rpos expresados en la superficie de fagos.
|
|
DE4211351A1
(de)
|
1992-04-04 |
1993-10-07 |
Behringwerke Ag |
Verfahren zur Analyse partikelverstärkter Agglutinationsreaktionen auf Zentrifugalanalysatoren durch Bestimmung der Trübungsaufhellung
|
|
AU3691093A
(en)
|
1992-04-14 |
1993-10-21 |
Hybritech Incorporated |
Methods of inhibiting the growth of multidrug resistant tumors
|
|
US5316920A
(en)
|
1992-04-17 |
1994-05-31 |
Dana-Faber Cancer Institute, Inc. |
Lymphocyte activation antigen HB15, a member of the immunoglobulin superfamily
|
|
US5710262A
(en)
|
1992-04-17 |
1998-01-20 |
Dana-Faber Cancer Institute, Inc. |
Nucleic acid encoding HB15 polypeptides
|
|
SG41929A1
(en)
|
1992-09-25 |
1997-08-15 |
Commw Scient Ind Res Org |
Target binding polypeptide
|
|
US20080152586A1
(en)
|
1992-09-25 |
2008-06-26 |
Avipep Pty Limited |
High avidity polyvalent and polyspecific reagents
|
|
US5837821A
(en)
|
1992-11-04 |
1998-11-17 |
City Of Hope |
Antibody construct
|
|
US5516637A
(en)
|
1994-06-10 |
1996-05-14 |
Dade International Inc. |
Method involving display of protein binding pairs on the surface of bacterial pili and bacteriophage
|
|
US5731168A
(en)
|
1995-03-01 |
1998-03-24 |
Genentech, Inc. |
Method for making heteromultimeric polypeptides
|
|
US6113898A
(en)
|
1995-06-07 |
2000-09-05 |
Idec Pharmaceuticals Corporation |
Human B7.1-specific primatized antibodies and transfectomas expressing said antibodies
|
|
AU725609C
(en)
|
1995-08-18 |
2002-01-03 |
Morphosys Ag |
Protein/(poly)peptide libraries
|
|
GB9603256D0
(en)
|
1996-02-16 |
1996-04-17 |
Wellcome Found |
Antibodies
|
|
US6541213B1
(en)
|
1996-03-29 |
2003-04-01 |
University Of Washington |
Microscale diffusion immunoassay
|
|
US6699658B1
(en)
|
1996-05-31 |
2004-03-02 |
Board Of Trustees Of The University Of Illinois |
Yeast cell surface display of proteins and uses thereof
|
|
CA2244326C
(en)
|
1997-08-11 |
2006-03-28 |
Shinichi Eda |
Microparticle enhanced light scattering agglutination assay and microparticle reagents therefor
|
|
WO1999022764A1
(en)
|
1997-10-31 |
1999-05-14 |
Genentech, Inc. |
Methods and compositions comprising glycoprotein glycoforms
|
|
ES2434961T5
(es)
|
1998-04-20 |
2018-01-18 |
Roche Glycart Ag |
Ingeniería de glicosilación de anticuerpos para mejorar la citotoxicidad celular dependiente del anticuerpo
|
|
US6562622B1
(en)
|
1998-05-08 |
2003-05-13 |
Diatech Pty, Ltd |
Continuous in vitro evolution
|
|
WO2000034317A2
(en)
|
1998-12-08 |
2000-06-15 |
Biovation Limited |
Method for reducing immunogenicity of proteins
|
|
US6737056B1
(en)
|
1999-01-15 |
2004-05-18 |
Genentech, Inc. |
Polypeptide variants with altered effector function
|
|
WO2000042430A1
(en)
|
1999-01-15 |
2000-07-20 |
Medtox Scientific, Inc. |
Lateral flow test strip
|
|
AU781547B2
(en)
*
|
1999-04-14 |
2005-05-26 |
Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The |
Compositions containing immunotoxins and agents that inhibit dendritic cell maturation for inducing immune tolerance to a graft
|
|
US7270969B2
(en)
|
1999-05-05 |
2007-09-18 |
Phylogica Limited |
Methods of constructing and screening diverse expression libraries
|
|
PT1355919E
(pt)
|
2000-12-12 |
2011-03-02 |
Medimmune Llc |
Moléculas com semivida longa, composições que as contêm e suas utilizações
|
|
MXPA05000511A
(es)
|
2001-07-12 |
2005-09-30 |
Jefferson Foote |
Anticuepros super humanizados.
|
|
US7205159B2
(en)
|
2001-08-20 |
2007-04-17 |
Proteome Systems Intellectual Property Pty Ltd. |
Diagnostic testing process and apparatus
|
|
AR039067A1
(es)
*
|
2001-11-09 |
2005-02-09 |
Pfizer Prod Inc |
Anticuerpos para cd40
|
|
US20040185040A1
(en)
|
2001-11-21 |
2004-09-23 |
Celltech R & D Limited |
Modulating immune responses
|
|
JP2005519586A
(ja)
*
|
2001-11-21 |
2005-07-07 |
セルテック アール アンド ディー, インコーポレイテッド |
Cd83遺伝子産物を利用したサイトカイン・レベルの操作法
|
|
US7317091B2
(en)
|
2002-03-01 |
2008-01-08 |
Xencor, Inc. |
Optimized Fc variants
|
|
AU2002950779A0
(en)
|
2002-08-15 |
2002-09-12 |
The Corporation Of The Trustees Of The Order Of The Sisters Of Mercy In Queensland |
A method of immunomodulation
|
|
US7217797B2
(en)
|
2002-10-15 |
2007-05-15 |
Pdl Biopharma, Inc. |
Alteration of FcRn binding affinities or serum half-lives of antibodies by mutagenesis
|
|
WO2004048552A2
(en)
*
|
2002-11-21 |
2004-06-10 |
Celltech R & D, Inc. |
Modulating immune responses
|
|
JP2006507510A
(ja)
|
2002-11-21 |
2006-03-02 |
インバーネス・メデイカル・スウイツツアーランド・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング |
組織低酸素症の体液マーカー
|
|
US7169898B2
(en)
*
|
2002-12-04 |
2007-01-30 |
Alexander Steinkasserer |
Soluble CD83 proteins and use thereof for the treatment or prevention of a disease or medical condition caused by dysfunction or undesired function of a cellular immune response involving T cells
|
|
JP2006524039A
(ja)
|
2003-01-09 |
2006-10-26 |
マクロジェニクス,インコーポレーテッド |
変異型Fc領域を含む抗体の同定および作製ならびにその利用法
|
|
AU2004245038A1
(en)
|
2003-06-02 |
2004-12-16 |
Alexion Pharmaceuticals, Inc. |
De-immunized anti-CD3 antibody
|
|
JP2007531707A
(ja)
|
2003-10-15 |
2007-11-08 |
ピーディーエル バイオファーマ, インコーポレイテッド |
IGの重鎖定常領域の位置250、314および/または428の変異誘発によるFc融合タンパク質血清半減期の改変
|
|
ES2672640T3
(es)
|
2003-11-05 |
2018-06-15 |
Roche Glycart Ag |
Moléculas de unión a antígeno con afinidad de unión a receptores Fc y función efectora incrementadas
|
|
US8802820B2
(en)
|
2004-11-12 |
2014-08-12 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
|
US20070135620A1
(en)
|
2004-11-12 |
2007-06-14 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
|
WO2006063150A2
(en)
*
|
2004-12-08 |
2006-06-15 |
Immunomedics, Inc. |
Methods and compositions for immunotherapy and detection of inflammatory and immune-dysregulatory disease, infectious disease, pathologic angiogenesis and cancer
|
|
US20090247455A1
(en)
|
2005-03-31 |
2009-10-01 |
Mark Fear |
Isolation of Inhibitors of IRES-Mediated Translation
|
|
CN101155914B
(zh)
*
|
2005-04-08 |
2013-03-06 |
阿戈斯治疗公司 |
树状细胞组合物和方法
|
|
KR20080068004A
(ko)
|
2005-08-15 |
2008-07-22 |
아라나 테라퓨틱스 리미티드 |
뉴 월드 영장류 구조형성영역을 가진 조작 항체
|
|
WO2007150020A1
(en)
*
|
2006-06-23 |
2007-12-27 |
Simon Paul M |
Targeted immune conjugates
|
|
EP1985305A1
(en)
|
2007-04-24 |
2008-10-29 |
Vivalis |
Duck embryonic derived stem cell lines for the production of viral vaccines
|
|
EP1995309A1
(en)
|
2007-05-21 |
2008-11-26 |
Vivalis |
Recombinant protein production in avian EBx® cells
|
|
EP2207803B1
(en)
|
2008-06-25 |
2013-05-01 |
Korea Research Institute of Bioscience and Biotechnology |
Cd9-specific human antibodies
|
|
AR074369A1
(es)
|
2008-11-20 |
2011-01-12 |
Genentech Inc |
Anticuerpos anti-unc 5b (receptor de netrina) y metodos de uso
|
|
WO2012088290A2
(en)
*
|
2010-12-22 |
2012-06-28 |
Abbott Laboratories |
Tri-variable domain binding proteins and uses thereof
|
|
JP2013040160A
(ja)
*
|
2011-07-01 |
2013-02-28 |
Genentech Inc |
自己免疫疾患を治療するための抗cd83アゴニスト抗体の使用
|
|
US9840559B2
(en)
|
2013-02-01 |
2017-12-12 |
The Regents Of The University Of California |
Anti-CD83 antibodies and use thereof
|
|
WO2016061617A1
(en)
|
2014-10-23 |
2016-04-28 |
Dendrocyte Biotech Pty Ltd |
Cd83 binding proteins and uses thereof
|
|
EP3681536A4
(en)
|
2017-09-13 |
2021-06-09 |
Kira Biotech Pty Limited |
TREATMENT METHOD
|