JP2016504417A5 - - Google Patents
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- Publication number
- JP2016504417A5 JP2016504417A5 JP2015552813A JP2015552813A JP2016504417A5 JP 2016504417 A5 JP2016504417 A5 JP 2016504417A5 JP 2015552813 A JP2015552813 A JP 2015552813A JP 2015552813 A JP2015552813 A JP 2015552813A JP 2016504417 A5 JP2016504417 A5 JP 2016504417A5
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361751735P | 2013-01-11 | 2013-01-11 | |
| US61/751,735 | 2013-01-11 | ||
| PCT/US2014/011076 WO2014110393A1 (en) | 2013-01-11 | 2014-01-10 | Intein mediated purification of protein |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016504417A JP2016504417A (ja) | 2016-02-12 |
| JP2016504417A5 true JP2016504417A5 (ja) | 2016-08-18 |
Family
ID=50030524
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015552813A Pending JP2016504417A (ja) | 2013-01-11 | 2014-01-10 | インテイン媒介によるタンパク質の精製 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US10087213B2 (ja) |
| EP (1) | EP2943573A1 (ja) |
| JP (1) | JP2016504417A (ja) |
| WO (1) | WO2014110393A1 (ja) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014110393A1 (en) | 2013-01-11 | 2014-07-17 | The Texas A&M University System | Intein mediated purification of protein |
| SI3215614T1 (sl) * | 2014-11-03 | 2019-11-29 | Merck Patent Gmbh | Topni fuzijski proteini inteina in postopki za čiščenje biomolekul |
| US10066027B2 (en) * | 2015-01-09 | 2018-09-04 | Ohio State Innovation Foundation | Protein production systems and methods thereof |
| SI3408292T1 (sl) * | 2016-01-29 | 2023-09-29 | The Trustees Of Princeton University | Razcepljeni inteini z izjemnim združevalnim delovanjem |
| KR101690186B1 (ko) * | 2016-09-29 | 2016-12-28 | 한국외국어대학교 연구산학협력단 | 인테인을 이용한 항균성 펩타이드의 제조방법 |
| WO2018091424A1 (en) * | 2016-11-16 | 2018-05-24 | Ge Healthcare Bioprocess R&D Ab | Improved chromatography resin, production and use thereof |
| TWI671314B (zh) * | 2018-06-29 | 2019-09-11 | 國立清華大學 | 自斷蛋白的活性控制及其應用 |
| US10479815B2 (en) | 2018-08-04 | 2019-11-19 | Sareh Arjmand | Protein purification using intein-hydrophobin tag and alcohol precipitation |
| US20220275027A1 (en) * | 2019-08-28 | 2022-09-01 | Trustees Of Princeton University | Atypical split inteins and uses thereof |
| GB201917046D0 (en) | 2019-11-22 | 2020-01-08 | Ge Healthcare Bioprocess R&D Ab | Improved protein production |
| US20220280617A1 (en) * | 2019-12-18 | 2022-09-08 | MVRIX Co., Ltd. | Method for safely producing botulinum neurotoxin |
| KR20220158004A (ko) * | 2020-03-25 | 2022-11-29 | 메르크 파텐트 게엠베하 | 단백질 정제를 위한 인테인-결합 수지의 재사용 |
| CA3216901A1 (en) | 2021-05-12 | 2022-11-17 | Cytiva Bioprocess R&D Ab | Improved protein purification |
| CN113480613B (zh) * | 2021-08-04 | 2022-04-15 | 江南大学 | 一种自剪切蛋白标签、改造方法及其应用 |
| CN113735941B (zh) * | 2021-08-13 | 2024-01-30 | 江南大学 | 一种蛋白纯化方法及其应用 |
| CN115074340B (zh) * | 2022-06-17 | 2023-02-28 | 广州市乾相生物科技有限公司 | 一种新内含肽及其在合成人源原弹性蛋白上的应用 |
| CN116731126B (zh) * | 2023-01-30 | 2024-02-23 | 态创生物科技(广州)有限公司 | 内含肽ChiATP、内含肽ChiATP-二肽-2融合蛋白及二肽-2的表达方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4476360B2 (ja) | 1995-06-28 | 2010-06-09 | ニユー・イングランド・バイオレイブズ・インコーポレイテツド | 改質タンパク質及びその製造法 |
| JP4749548B2 (ja) * | 1998-09-30 | 2011-08-17 | ニユー・イングランド・バイオレイブズ・インコーポレイテツド | インテイン媒介ペプチド連結 |
| JP2003525584A (ja) | 1999-02-12 | 2003-09-02 | ニユー・イングランド・バイオレイブズ・インコーポレイテツド | 発現タンパク質のインテイン媒介タンパク質連結方法 |
| NZ511799A (en) | 2001-05-18 | 2004-01-30 | Univ Otago | A eukaryotic intein (Cne PRP8) from Cryptococcus neoformans and potential use as a molecular target for treatment of severe microbial infection |
| US20060141570A1 (en) | 2004-11-16 | 2006-06-29 | Wood David W | Intein-mediated protein purification using in vivo expression of an aggregator protein |
| EP2665744B1 (en) * | 2011-01-20 | 2015-04-08 | University Of Rochester | Macrocyclic compounds with a hybrid peptidic/non-peptidic backbone and methods for their preparation |
| WO2014110393A1 (en) | 2013-01-11 | 2014-07-17 | The Texas A&M University System | Intein mediated purification of protein |
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2014
- 2014-01-10 WO PCT/US2014/011076 patent/WO2014110393A1/en active Application Filing
- 2014-01-10 JP JP2015552813A patent/JP2016504417A/ja active Pending
- 2014-01-10 US US14/760,392 patent/US10087213B2/en active Active
- 2014-01-10 EP EP14702146.3A patent/EP2943573A1/en not_active Withdrawn