JP2016504041A5 - - Google Patents
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- Publication number
- JP2016504041A5 JP2016504041A5 JP2015552042A JP2015552042A JP2016504041A5 JP 2016504041 A5 JP2016504041 A5 JP 2016504041A5 JP 2015552042 A JP2015552042 A JP 2015552042A JP 2015552042 A JP2015552042 A JP 2015552042A JP 2016504041 A5 JP2016504041 A5 JP 2016504041A5
- Authority
- JP
- Japan
- Prior art keywords
- double
- stranded oligonucleotide
- strand
- chromophore
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108091034117 Oligonucleotide Proteins 0.000 claims 22
- 238000000034 method Methods 0.000 claims 11
- 150000007523 nucleic acids Chemical class 0.000 claims 11
- 238000002844 melting Methods 0.000 claims 10
- 230000008018 melting Effects 0.000 claims 10
- 108020004707 nucleic acids Proteins 0.000 claims 8
- 102000039446 nucleic acids Human genes 0.000 claims 8
- 108020004414 DNA Proteins 0.000 claims 7
- 102000053602 DNA Human genes 0.000 claims 7
- 230000004568 DNA-binding Effects 0.000 claims 7
- 239000002773 nucleotide Substances 0.000 claims 5
- 125000003729 nucleotide group Chemical group 0.000 claims 5
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 3
- 238000002474 experimental method Methods 0.000 claims 3
- 239000003153 chemical reaction reagent Substances 0.000 claims 2
- 239000011541 reaction mixture Substances 0.000 claims 2
- UDGUGZTYGWUUSG-UHFFFAOYSA-N 4-[4-[[2,5-dimethoxy-4-[(4-nitrophenyl)diazenyl]phenyl]diazenyl]-n-methylanilino]butanoic acid Chemical compound COC=1C=C(N=NC=2C=CC(=CC=2)N(C)CCCC(O)=O)C(OC)=CC=1N=NC1=CC=C([N+]([O-])=O)C=C1 UDGUGZTYGWUUSG-UHFFFAOYSA-N 0.000 claims 1
- 230000000295 complement effect Effects 0.000 claims 1
- 230000003247 decreasing effect Effects 0.000 claims 1
- 238000012544 monitoring process Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13150790 | 2013-01-10 | ||
| EP13150790.7 | 2013-01-10 | ||
| PCT/EP2014/050243 WO2014108446A1 (en) | 2013-01-10 | 2014-01-08 | Improved calibration of high resolution melting |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016504041A JP2016504041A (ja) | 2016-02-12 |
| JP2016504041A5 true JP2016504041A5 (https=) | 2016-09-23 |
| JP6389473B2 JP6389473B2 (ja) | 2018-09-12 |
Family
ID=47561350
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015552042A Expired - Fee Related JP6389473B2 (ja) | 2013-01-10 | 2014-01-08 | 高解像能融解の較正の改善 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20150315634A1 (https=) |
| EP (1) | EP2943587A1 (https=) |
| JP (1) | JP6389473B2 (https=) |
| CN (1) | CN104838017B (https=) |
| CA (1) | CA2896616C (https=) |
| WO (1) | WO2014108446A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2654571C2 (ru) * | 2016-02-25 | 2018-05-21 | Общество с ограниченной ответственностью "Научно-производственная фирма ДНК-Технология" (ООО "НПФ ДНК-Технология") | Способ оптической и температурной валидации приборов для ПЦР-исследований в режиме реального времени |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4458066A (en) | 1980-02-29 | 1984-07-03 | University Patents, Inc. | Process for preparing polynucleotides |
| ATE88761T1 (de) * | 1986-01-10 | 1993-05-15 | Amoco Corp | Kompetitiver homogener test. |
| US5935791A (en) * | 1997-09-23 | 1999-08-10 | Becton, Dickinson And Company | Detection of nucleic acids by fluorescence quenching |
| US20040022764A1 (en) * | 2002-07-31 | 2004-02-05 | Hanan Polansky | Inhibition of microcompetition with a foreign polynucleotide as treatment of chronic disease |
| CA2501144C (en) | 2002-10-23 | 2015-10-06 | University Of Utah Research Foundation | Amplicon melting analysis with saturation dyes |
| US7785786B2 (en) * | 2006-01-23 | 2010-08-31 | Quest Diagnostics Investments Incorporated | Methods for detecting nucleic acids using multiple signals |
| FR2906532B1 (fr) * | 2006-09-28 | 2008-12-12 | Biomerieux Sa | Nouvel oligonucleotide marque |
| EP2116614A1 (en) * | 2008-05-06 | 2009-11-11 | Qiagen GmbH | Simultaneous detection of multiple nucleic acid sequences in a reaction |
| US9542526B2 (en) * | 2009-03-10 | 2017-01-10 | Canon U.S. Life Sciences, Inc. | Method and system for temperature correction in thermal melt analysis |
| CA2836907C (en) * | 2011-06-06 | 2020-07-21 | Waters Technologies Corporation | Compositions, methods, and kits for quantifying target analytes in a sample |
| US20130157376A1 (en) * | 2011-12-20 | 2013-06-20 | Idaho Technology, Inc. | Thermal Cycler Calibration Device and Related Methods |
| EP2722399A1 (en) * | 2012-10-18 | 2014-04-23 | Roche Diagniostics GmbH | Method for preventing high molecular weight products during amplification |
-
2014
- 2014-01-08 WO PCT/EP2014/050243 patent/WO2014108446A1/en not_active Ceased
- 2014-01-08 EP EP14700170.5A patent/EP2943587A1/en not_active Withdrawn
- 2014-01-08 CA CA2896616A patent/CA2896616C/en not_active Expired - Fee Related
- 2014-01-08 JP JP2015552042A patent/JP6389473B2/ja not_active Expired - Fee Related
- 2014-01-08 CN CN201480003348.4A patent/CN104838017B/zh not_active Expired - Fee Related
-
2015
- 2015-07-06 US US14/792,224 patent/US20150315634A1/en not_active Abandoned
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