JP2016503405A - タンパク質症を処置するための組成物および方法 - Google Patents
タンパク質症を処置するための組成物および方法 Download PDFInfo
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- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
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- C—CHEMISTRY; METALLURGY
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- C12Y—ENZYMES
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Landscapes
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| JP2019527821A (ja) * | 2016-07-01 | 2019-10-03 | セントジーン アーゲー | ドラッガブルターゲットとしてのリゾＧｂ１の使用 |
| JP2020537543A (ja) * | 2017-10-03 | 2020-12-24 | プリベイル セラピューティクス, インコーポレーテッドPrevail Therapeutics, Inc. | ライソゾーム病の遺伝子治療 |
| JP2020537544A (ja) * | 2017-10-03 | 2020-12-24 | プリベイル セラピューティクス, インコーポレーテッドPrevail Therapeutics, Inc. | ライソゾーム病の遺伝子治療 |
| JP2021500049A (ja) * | 2017-10-23 | 2021-01-07 | プリベイル セラピューティクス, インコーポレーテッドPrevail Therapeutics, Inc. | 神経変性疾患の遺伝子治療 |
| JP2021501135A (ja) * | 2017-10-26 | 2021-01-14 | シャイア ヒューマン ジェネティック セラピーズ インコーポレイテッド | グルコセレブロシダーゼ及びイソファゴミンを含む製剤 |
| JP2021059586A (ja) * | 2016-04-29 | 2021-04-15 | オーファザイム エー／エス | グルコセレブロシダーゼ関連障害を治療するためのアリモクロモル |
| JP2022526021A (ja) * | 2019-04-10 | 2022-05-20 | プリベイル セラピューティクス，インコーポレーテッド | リソソーム障害のための遺伝子療法 |
| JP2023545462A (ja) * | 2020-10-14 | 2023-10-30 | デナリ セラピューティクス インコーポレイテッド | 前頭側頭型認知症を治療及びモニタリングするための方法 |
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| ES2385735T3 (es) | 2008-06-26 | 2012-07-31 | Orphazyme Aps | Uso de Hsp70 como regulador de la actividad enzimática |
| AU2011335545A1 (en) | 2010-11-30 | 2013-06-13 | Orphazyme Aps | Methods for increasing intracellular activity of Hsp70 |
| KR102804202B1 (ko) | 2014-09-15 | 2025-05-12 | 제브라 덴마크 에이/에스 | 아리모클로몰 제제 |
| CA2985235A1 (en) * | 2015-05-07 | 2016-11-10 | Shire Human Genetic Therapies, Inc. | Glucocerebrosidase gene therapy for parkinson's disease |
| CA3030261A1 (en) * | 2015-07-21 | 2017-01-26 | Thomas Jefferson University | Gene therapies for neurodegenerative disorders targeting ganglioside biosynthetic pathways |
| CA3011719A1 (en) * | 2016-01-21 | 2017-07-27 | Protein Dynamic Solutions Llc | Method and system for spectral data analysis |
| WO2017178029A1 (en) | 2016-04-13 | 2017-10-19 | Orphazyme Aps | Heat shock proteins and cholesterol homeostasis |
| AU2018346102B2 (en) | 2017-10-03 | 2023-05-11 | Prevail Therapeutics, Inc. | Gene therapies for lysosomal disorders |
| US20210041461A1 (en) * | 2018-03-14 | 2021-02-11 | Yissum Research Developmen Company Of The Hebrew University Of Jerusalem Ltd | Detection of phospho-serine 129 alpha-synuclein in blood cells as a biomarker for synucleinopathies |
| KR20210150486A (ko) | 2019-04-10 | 2021-12-10 | 프리베일 테라퓨틱스, 인크. | 리소좀 장애에 대한 유전자 요법 |
| EP3986412A4 (en) | 2019-06-21 | 2023-11-15 | The Broad Institute, Inc. | AGENTS TO REVERSE TOXIC PROTEINOPATHIES |
| MX2023000968A (es) | 2020-08-06 | 2023-03-01 | Fundacion Para La Investig Medica Aplicada | Particulas virales para usarse en el tratamiento contra tauopatias tales como enfermedad de alzheimer mediante terapia genica. |
| MX2023005954A (es) | 2020-11-19 | 2023-09-04 | Zevra Denmark As | Procesos para preparar citrato de arimoclomol e intermediarios del mismo. |
| CN112569354B (zh) * | 2020-12-29 | 2022-06-10 | 四川大学华西医院 | tau蛋白及其基因作为药物靶点在制备治疗糖尿病药物中的应用 |
| EP4448762A1 (en) * | 2021-12-17 | 2024-10-23 | F. Hoffmann-La Roche AG | Oligonucleotides capable of increasing glucocerebrosidase expression |
| EP4448763A1 (en) * | 2021-12-17 | 2024-10-23 | F. Hoffmann-La Roche AG | Oligonucleotide gba agonists |
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| US7446098B2 (en) * | 2003-02-18 | 2008-11-04 | Mount Sinai School Of Medicine Of New York University | Combination therapy for treating protein deficiencies |
| US7765583B2 (en) | 2005-02-28 | 2010-07-27 | France Telecom | System and method for managing virtual user domains |
| KR101402554B1 (ko) * | 2006-06-23 | 2014-06-19 | 아미쿠스 세라퓨틱스, 인코포레이티드 | β-글루코세레브로시다제의 활성 증진에 의한 신경계 장애 치료 방법 |
| HUE027278T2 (en) * | 2007-05-16 | 2016-11-28 | Brigham & Womens Hospital Inc | Treatment of synucleinopathies |
| WO2012177997A1 (en) | 2011-06-22 | 2012-12-27 | The General Hospital Corporation | Treatment of proteinopathies |
| AU2013240187A1 (en) | 2012-03-28 | 2014-10-30 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Salicylic acid derivatives useful as glucocerebrosidase activators |
-
2013
- 2013-11-04 MX MX2015005722A patent/MX2015005722A/es unknown
- 2013-11-04 HK HK16102536.9A patent/HK1214521A1/zh unknown
- 2013-11-04 WO PCT/US2013/068242 patent/WO2014071282A1/en not_active Ceased
- 2013-11-04 MA MA38144A patent/MA38144A1/fr unknown
- 2013-11-04 CA CA2889990A patent/CA2889990A1/en not_active Abandoned
- 2013-11-04 US US14/440,818 patent/US20150284472A1/en not_active Abandoned
- 2013-11-04 SG SG11201502989XA patent/SG11201502989XA/en unknown
- 2013-11-04 AU AU2013337354A patent/AU2013337354A1/en not_active Abandoned
- 2013-11-04 CN CN201380069582.2A patent/CN104902923A/zh active Pending
- 2013-11-04 TW TW102139891A patent/TW201427695A/zh unknown
- 2013-11-04 JP JP2015540845A patent/JP2016503405A/ja not_active Abandoned
- 2013-11-04 EA EA201590880A patent/EA201590880A1/ru unknown
- 2013-11-04 EP EP13789690.8A patent/EP2914281A1/en not_active Withdrawn
- 2013-11-04 BR BR112015009746A patent/BR112015009746A2/pt not_active IP Right Cessation
- 2013-11-04 KR KR1020157013541A patent/KR20150079751A/ko not_active Withdrawn
- 2013-11-05 AR ARP130104033A patent/AR093355A1/es unknown
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2015
- 2015-04-17 ZA ZA2015/02618A patent/ZA201502618B/en unknown
- 2015-04-20 PH PH12015500879A patent/PH12015500879A1/en unknown
- 2015-04-21 IL IL238416A patent/IL238416A0/en unknown
- 2015-04-28 CR CR20150216A patent/CR20150216A/es unknown
- 2015-04-30 CL CL2015001157A patent/CL2015001157A1/es unknown
- 2015-05-04 TN TNP2015000171A patent/TN2015000171A1/fr unknown
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| JP2021059586A (ja) * | 2016-04-29 | 2021-04-15 | オーファザイム エー／エス | グルコセレブロシダーゼ関連障害を治療するためのアリモクロモル |
| JP2019527821A (ja) * | 2016-07-01 | 2019-10-03 | セントジーン アーゲー | ドラッガブルターゲットとしてのリゾＧｂ１の使用 |
| JP7253800B2 (ja) | 2016-08-03 | 2023-04-07 | ユニヴァーシティ オブ サウス フロリダ | 神経障害治療用のリーリン組成物 |
| JP2019524775A (ja) * | 2016-08-03 | 2019-09-05 | ユニヴァーシティ オブ サウス フロリダ | 神経障害治療用のリーリン組成物 |
| JP2020537544A (ja) * | 2017-10-03 | 2020-12-24 | プリベイル セラピューティクス, インコーポレーテッドPrevail Therapeutics, Inc. | ライソゾーム病の遺伝子治療 |
| JP2020537543A (ja) * | 2017-10-03 | 2020-12-24 | プリベイル セラピューティクス, インコーポレーテッドPrevail Therapeutics, Inc. | ライソゾーム病の遺伝子治療 |
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| JP2023086740A (ja) * | 2017-10-03 | 2023-06-22 | プリベイル セラピューティクス，インコーポレーテッド | ライソゾーム病の遺伝子治療 |
| JP7361037B2 (ja) | 2017-10-03 | 2023-10-13 | プリベイル セラピューティクス，インコーポレーテッド | ライソゾーム病の遺伝子治療 |
| JP2021500049A (ja) * | 2017-10-23 | 2021-01-07 | プリベイル セラピューティクス, インコーポレーテッドPrevail Therapeutics, Inc. | 神経変性疾患の遺伝子治療 |
| JP7413256B2 (ja) | 2017-10-23 | 2024-01-15 | プリベイル セラピューティクス，インコーポレーテッド | 神経変性疾患の遺伝子治療 |
| JP2021501135A (ja) * | 2017-10-26 | 2021-01-14 | シャイア ヒューマン ジェネティック セラピーズ インコーポレイテッド | グルコセレブロシダーゼ及びイソファゴミンを含む製剤 |
| JP2022526021A (ja) * | 2019-04-10 | 2022-05-20 | プリベイル セラピューティクス，インコーポレーテッド | リソソーム障害のための遺伝子療法 |
| JP7664848B2 (ja) | 2019-04-10 | 2025-04-18 | プリベイル セラピューティクス，インコーポレーテッド | リソソーム障害のための遺伝子療法 |
| JP2023545462A (ja) * | 2020-10-14 | 2023-10-30 | デナリ セラピューティクス インコーポレイテッド | 前頭側頭型認知症を治療及びモニタリングするための方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| HK1214521A1 (zh) | 2016-07-29 |
| ZA201502618B (en) | 2016-01-27 |
| PH12015500879A1 (en) | 2015-06-29 |
| CL2015001157A1 (es) | 2015-10-16 |
| EP2914281A1 (en) | 2015-09-09 |
| MA38144A1 (fr) | 2018-08-31 |
| EA201590880A1 (ru) | 2015-09-30 |
| AU2013337354A1 (en) | 2015-05-21 |
| BR112015009746A2 (pt) | 2017-08-15 |
| CR20150216A (es) | 2015-05-29 |
| AR093355A1 (es) | 2015-06-03 |
| IL238416A0 (en) | 2015-06-30 |
| MX2015005722A (es) | 2016-01-12 |
| SG11201502989XA (en) | 2015-05-28 |
| WO2014071282A1 (en) | 2014-05-08 |
| KR20150079751A (ko) | 2015-07-08 |
| TW201427695A (zh) | 2014-07-16 |
| CN104902923A (zh) | 2015-09-09 |
| TN2015000171A1 (fr) | 2016-10-03 |
| CA2889990A1 (en) | 2014-05-08 |
| US20150284472A1 (en) | 2015-10-08 |
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