JP2016503065A5 - - Google Patents
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- JP2016503065A5 JP2016503065A5 JP2015549784A JP2015549784A JP2016503065A5 JP 2016503065 A5 JP2016503065 A5 JP 2016503065A5 JP 2015549784 A JP2015549784 A JP 2015549784A JP 2015549784 A JP2015549784 A JP 2015549784A JP 2016503065 A5 JP2016503065 A5 JP 2016503065A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- amino acid
- acid sequence
- sequence shown
- tau
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261745410P | 2012-12-21 | 2012-12-21 | |
| US61/745,410 | 2012-12-21 | ||
| PCT/US2013/076952 WO2014100600A2 (en) | 2012-12-21 | 2013-12-20 | Human anti-tau antibodies |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016503065A JP2016503065A (ja) | 2016-02-01 |
| JP2016503065A5 true JP2016503065A5 (https=) | 2016-09-01 |
| JP6284548B2 JP6284548B2 (ja) | 2018-02-28 |
Family
ID=49920689
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015549784A Expired - Fee Related JP6284548B2 (ja) | 2012-12-21 | 2013-12-20 | ヒト抗タウ抗体 |
Country Status (27)
| Country | Link |
|---|---|
| US (4) | US9598484B2 (https=) |
| EP (2) | EP3792278A3 (https=) |
| JP (1) | JP6284548B2 (https=) |
| KR (1) | KR102234324B1 (https=) |
| CN (2) | CN111205368B (https=) |
| AU (1) | AU2013361107B2 (https=) |
| BR (1) | BR112015014751A8 (https=) |
| CA (1) | CA2896066C (https=) |
| CY (1) | CY1123518T1 (https=) |
| DK (1) | DK2935326T3 (https=) |
| EA (1) | EA035932B1 (https=) |
| ES (1) | ES2816700T3 (https=) |
| HR (1) | HRP20201422T1 (https=) |
| HU (1) | HUE051320T2 (https=) |
| IL (1) | IL239556B (https=) |
| LT (1) | LT2935326T (https=) |
| MX (1) | MX2015008024A (https=) |
| MY (1) | MY184251A (https=) |
| PH (2) | PH12015501420B1 (https=) |
| PL (1) | PL2935326T3 (https=) |
| PT (1) | PT2935326T (https=) |
| RS (1) | RS60899B1 (https=) |
| SG (2) | SG10201705104UA (https=) |
| SI (1) | SI2935326T1 (https=) |
| SM (1) | SMT202000512T1 (https=) |
| WO (1) | WO2014100600A2 (https=) |
| ZA (1) | ZA201504898B (https=) |
Families Citing this family (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112013008765B8 (pt) | 2010-10-11 | 2023-05-02 | Biogen Idec Int Neuroscience Gmbh | Anticorpos monoclonais anti-tau humano isolados ou um fragmento de ligação à tau dos mesmos, métodos de preparação dos mesmos, polinucleotídeo ou polinucleotídeos, vetor ou vetores, composição, método in vitro de diagnóstico ou monitoramento da progressão de uma tauopatia neurodegenerativa em um indivíduo humano, método in vitro para diagnosticar uma tauopatia neurodegenerativa em um indivíduo humano, e kit útil para o diagnóstico de uma tauopatia neurodegenerativa |
| HK1209768A1 (en) | 2012-07-03 | 2016-04-08 | Washington University | Antibodies to tau |
| US12024568B2 (en) | 2012-09-13 | 2024-07-02 | Cornell University | Treatment of brain cancers using central nervous system mediated gene transfer of monoclonal antibodies |
| CA2902026C (en) | 2013-03-13 | 2023-08-29 | Prothena Biosciences Limited | Tau immunotherapy |
| WO2015035190A1 (en) * | 2013-09-05 | 2015-03-12 | Cornell University | Gene therapy for alzheimer's and other neurodegenerative diseases and conditions |
| ZA201608812B (en) * | 2014-06-26 | 2019-08-28 | Janssen Vaccines & Prevention Bv | Antibodies and antigen-binding fragments that specifically bind to microtubule-associated protein tau |
| WO2015197820A1 (en) * | 2014-06-26 | 2015-12-30 | Crucell Holland B.V. | Antibodies and antigen-binding fragments that specifically bind to microtubule-associated protein tau |
| TWI664190B (zh) | 2014-06-27 | 2019-07-01 | 美商Ｃ２Ｎ醫療診斷有限責任公司 | 人類化抗－ｔａｕ抗體 |
| DE102014013571A1 (de) | 2014-09-18 | 2016-03-24 | Aj Roboscreen Gmbh | Monoklonaler Antikörper gegen humanes TAU-Protein |
| SI3221349T1 (sl) | 2014-11-19 | 2021-02-26 | Axon Neuroscience Se | Humanizirano tau protitelo pri alzheimerjevi bolezni |
| US10202444B2 (en) | 2015-02-24 | 2019-02-12 | Rpeptide, Llc | Anti-tau antibodies |
| AR103713A1 (es) * | 2015-02-26 | 2017-05-31 | Lilly Co Eli | Anticuerpos contra tau y sus usos |
| EP4465050A3 (en) | 2015-06-05 | 2025-06-11 | Genentech, Inc. | Anti-tau antibodies and methods of use |
| CA2991264C (en) | 2015-07-06 | 2023-10-10 | Ucb Biopharma Sprl | Tau-binding antibodies |
| KR102770650B1 (ko) | 2015-07-06 | 2025-02-19 | 유씨비 바이오파마 에스알엘 | 타우 결합 항체 |
| DK3430397T3 (da) | 2016-03-14 | 2022-05-02 | Biogen Int Neuroscience Gmbh | Antistofafhængig cellemedieret fagocytoseassay til pålidelig måling af optagelse af aggregerede proteiner |
| EP3452507B1 (en) | 2016-05-02 | 2022-10-19 | Prothena Biosciences Limited | Tau immunotherapy |
| CA3022515A1 (en) * | 2016-05-02 | 2017-11-09 | Prothena Biosciences Limited | Antibodies recognizing tau |
| PE20190208A1 (es) * | 2016-05-02 | 2019-02-07 | Prothena Biosciences Ltd | Anticuerpos que reconocen tau |
| CA3026598A1 (en) | 2016-06-07 | 2017-12-14 | Biogen International Neuroscience Gmbh | Methods for treating alzheimer's disease |
| US20190330318A1 (en) | 2016-07-25 | 2019-10-31 | Biogen Ma Inc. | Anti-hspa5 (grp78) antibodies and uses thereof |
| EP3496750A2 (en) | 2016-08-09 | 2019-06-19 | Eli Lilly and Company | Combination therapy |
| CN117820467A (zh) * | 2016-12-07 | 2024-04-05 | 基因泰克公司 | 抗tau抗体和使用方法 |
| MA48595A (fr) | 2016-12-07 | 2020-03-18 | Ac Immune Sa | Anticorps anti-tau et leurs méthodes d'utilisation |
| MA47163A (fr) | 2016-12-16 | 2019-11-06 | Biogen Ma Inc | Facteur 11 de différenciation de croissance activé protéolytiquement stabilisé |
| BR112019017021A2 (pt) | 2017-02-17 | 2020-04-14 | Denali Therapeutics Inc | anticorpos anti-tau e métodos de uso dos mesmos |
| JP2018139530A (ja) | 2017-02-27 | 2018-09-13 | 帝人ファーマ株式会社 | 認知症治療又は予防のためのヒト化抗体及びその製造方法、並びにそれを用いた認知症治療剤又は予防剤 |
| KR20190133162A (ko) | 2017-03-28 | 2019-12-02 | 제넨테크, 인크. | 신경퇴행성 질병의 치료 방법 |
| CN110446925A (zh) * | 2017-03-28 | 2019-11-12 | 扬森疫苗与预防公司 | 检测Tau蛋白聚集调节化合物的方法 |
| CN110881274B (zh) | 2017-05-02 | 2024-11-15 | 普罗塞纳生物科学有限公司 | 识别tau的抗体 |
| EP3697814A1 (en) | 2017-10-16 | 2020-08-26 | Eisai R&D Management Co., Ltd. | Anti-tau antibodies and uses thereof |
| WO2019133799A1 (en) * | 2017-12-29 | 2019-07-04 | University Of Florida Research Foundation | Monoclonal antibodies targeting microtubule-binding domain of tau protein |
| MA53338A (fr) * | 2018-03-05 | 2022-01-05 | Janssen Pharmaceutica Nv | Dosages pour détecter la neurodégénérescence |
| CN111918875A (zh) * | 2018-03-11 | 2020-11-10 | 库罗什·沙帕桑 | 构象-特异性的抗神经毒性tau蛋白的抗体 |
| CA3107788A1 (en) | 2018-07-31 | 2020-02-06 | Eli Lilly And Company | Combination of anti-tau antibody and oga inhibitor for treatment of diseases characterized by aberrant tau aggregation |
| WO2020079113A1 (en) * | 2018-10-19 | 2020-04-23 | Janssen Vaccines & Prevention B.V. | Anti-synuclein antibodies |
| CN113508135A (zh) | 2018-10-29 | 2021-10-15 | 比奥根Ma公司 | 增强血脑屏障转运的人源化和稳定化的fc5变体 |
| SG11202104549TA (en) * | 2018-11-08 | 2021-05-28 | Prothena Biosciences Ltd | Antibodies recognizing tau |
| MX2021014473A (es) * | 2019-05-31 | 2022-01-06 | Lilly Co Eli | Compuestos y metodos dirigidos a la tau humana. |
| US20220260593A1 (en) * | 2019-06-13 | 2022-08-18 | Michael Sierks | Targets and methods of diagnosing, monitoring and treating frontotemporal dementia |
| AU2019457621A1 (en) * | 2019-07-23 | 2022-02-17 | Shanghaitech University | ASIC1 channel antagonist antibody |
| JP7181438B2 (ja) | 2019-08-06 | 2022-11-30 | アプリノイア セラピューティクス リミテッド | 病理学的タウ種に結合する抗体及びその使用 |
| CN114502480B (zh) * | 2019-10-25 | 2024-04-30 | 东洋纺株式会社 | 能够激光印字的膜及使用了该膜的包装体 |
| CA3183835A1 (en) | 2020-06-25 | 2021-12-30 | Jeanne E. Baker | High affinity antibodies targeting tau phosphorylated at serine 413 |
| GB202010652D0 (en) * | 2020-07-10 | 2020-08-26 | Wista Lab Ltd | Anti-tau antibodies |
| US20240025954A1 (en) * | 2020-10-26 | 2024-01-25 | Sola Biosciences Llc | Compositions and Methods for the Treatment of Alzheimer's Disease |
| EP4263599A1 (en) * | 2020-12-16 | 2023-10-25 | Voyager Therapeutics, Inc. | Tau binding compounds |
| CL2021001380A1 (es) | 2021-05-26 | 2022-01-14 | Corporacion Centro Int De Biomedicina Icc | Generación de un nuevo anticuerpo monoclonal sitio específico para la proteína tau y su uso como herramienta en biomarcadores específicos para la detección temprana de enfermedades neurodegenerativas y patologías involucradas con la proteína tau como alzheimer y otras demencias. |
| IL310382A (en) | 2021-08-27 | 2024-03-01 | Genentech Inc | Methods for treating tau pathologies |
| WO2023099788A1 (en) | 2021-12-03 | 2023-06-08 | Neurimmune Ag | Novel potency assay for antibody-based drugs and useful means therefor |
| EP4494141A1 (en) | 2022-03-14 | 2025-01-22 | Genentech, Inc. | Predicting neurodegenerative diseases based on speech analyses |
| EP4544544A1 (en) | 2022-06-21 | 2025-04-30 | Genentech Inc. | Detecting longitudinal progression of alzheimer's disease (ad) based on speech analyses |
| CA3266790A1 (en) | 2022-09-15 | 2024-03-21 | Voyager Therapeutics, Inc. | TAU PROTEIN BINDING COMPOUNDS |
| WO2025090985A1 (en) * | 2023-10-27 | 2025-05-01 | Duke University | Compositions comprising chimeric antigen receptors targeting citrullinated vimentin and methods of use thereof |
| CN117946264B (zh) * | 2024-03-21 | 2024-06-04 | 江西赛基生物技术有限公司 | 一种抗Tau蛋白单克隆抗体及其应用 |
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2013
- 2013-12-20 PT PT138186374T patent/PT2935326T/pt unknown
- 2013-12-20 RS RS20201060A patent/RS60899B1/sr unknown
- 2013-12-20 MY MYPI2015001581A patent/MY184251A/en unknown
- 2013-12-20 MX MX2015008024A patent/MX2015008024A/es active IP Right Grant
- 2013-12-20 SI SI201331780T patent/SI2935326T1/sl unknown
- 2013-12-20 SG SG10201705104UA patent/SG10201705104UA/en unknown
- 2013-12-20 EP EP20178431.1A patent/EP3792278A3/en not_active Withdrawn
- 2013-12-20 LT LTEP13818637.4T patent/LT2935326T/lt unknown
- 2013-12-20 CA CA2896066A patent/CA2896066C/en active Active
- 2013-12-20 SG SG11201504822VA patent/SG11201504822VA/en unknown
- 2013-12-20 SM SM20200512T patent/SMT202000512T1/it unknown
- 2013-12-20 PL PL13818637.4T patent/PL2935326T3/pl unknown
- 2013-12-20 CN CN201911004609.5A patent/CN111205368B/zh not_active Expired - Fee Related
- 2013-12-20 AU AU2013361107A patent/AU2013361107B2/en not_active Ceased
- 2013-12-20 US US14/654,176 patent/US9598484B2/en not_active Expired - Fee Related
- 2013-12-20 ES ES13818637T patent/ES2816700T3/es active Active
- 2013-12-20 KR KR1020157019330A patent/KR102234324B1/ko not_active Expired - Fee Related
- 2013-12-20 CN CN201380073531.7A patent/CN105324394B/zh not_active Expired - Fee Related
- 2013-12-20 EA EA201591020A patent/EA035932B1/ru unknown
- 2013-12-20 HU HUE13818637A patent/HUE051320T2/hu unknown
- 2013-12-20 DK DK13818637.4T patent/DK2935326T3/da active
- 2013-12-20 EP EP13818637.4A patent/EP2935326B1/en active Active
- 2013-12-20 JP JP2015549784A patent/JP6284548B2/ja not_active Expired - Fee Related
- 2013-12-20 WO PCT/US2013/076952 patent/WO2014100600A2/en not_active Ceased
- 2013-12-20 BR BR112015014751A patent/BR112015014751A8/pt not_active IP Right Cessation
- 2013-12-20 HR HRP20201422TT patent/HRP20201422T1/hr unknown
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2015
- 2015-06-19 PH PH12015501420A patent/PH12015501420B1/en unknown
- 2015-06-21 IL IL239556A patent/IL239556B/en active IP Right Grant
- 2015-07-08 ZA ZA201504898A patent/ZA201504898B/en unknown
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2017
- 2017-02-08 US US15/427,843 patent/US20170369560A1/en not_active Abandoned
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2018
- 2018-06-27 US US16/020,346 patent/US20190169274A1/en not_active Abandoned
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2019
- 2019-09-24 US US16/580,152 patent/US20200262895A1/en not_active Abandoned
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2020
- 2020-09-09 CY CY20201100854T patent/CY1123518T1/el unknown
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2021
- 2021-01-13 PH PH12021550083A patent/PH12021550083A1/en unknown