JP2016500250A5 - - Google Patents
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- Publication number
- JP2016500250A5 JP2016500250A5 JP2015543148A JP2015543148A JP2016500250A5 JP 2016500250 A5 JP2016500250 A5 JP 2016500250A5 JP 2015543148 A JP2015543148 A JP 2015543148A JP 2015543148 A JP2015543148 A JP 2015543148A JP 2016500250 A5 JP2016500250 A5 JP 2016500250A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- protein
- modified protein
- acid residues
- reference secreted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
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- 125000000539 amino acid group Chemical group 0.000 claims 28
- 102000004169 proteins and genes Human genes 0.000 claims 24
- 108090000623 proteins and genes Proteins 0.000 claims 24
- 102000035118 modified proteins Human genes 0.000 claims 23
- 108091005573 modified proteins Proteins 0.000 claims 23
- 235000020776 essential amino acid Nutrition 0.000 claims 16
- 239000003797 essential amino acid Substances 0.000 claims 16
- 238000006467 substitution reaction Methods 0.000 claims 11
- 150000001413 amino acids Chemical class 0.000 claims 9
- 150000007523 nucleic acids Chemical class 0.000 claims 7
- 244000005700 microbiome Species 0.000 claims 5
- 239000000203 mixture Substances 0.000 claims 5
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 4
- 229940024606 amino acid Drugs 0.000 claims 4
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 claims 3
- 108020004707 nucleic acids Proteins 0.000 claims 3
- 102000039446 nucleic acids Human genes 0.000 claims 3
- 239000004475 Arginine Substances 0.000 claims 2
- AGPKZVBTJJNPAG-WHFBIAKZSA-N L-isoleucine Chemical compound CC[C@H](C)[C@H](N)C(O)=O AGPKZVBTJJNPAG-WHFBIAKZSA-N 0.000 claims 2
- ROHFNLRQFUQHCH-YFKPBYRVSA-N L-leucine Chemical compound CC(C)C[C@H](N)C(O)=O ROHFNLRQFUQHCH-YFKPBYRVSA-N 0.000 claims 2
- COLNVLDHVKWLRT-QMMMGPOBSA-N L-phenylalanine Chemical compound OC(=O)[C@@H](N)CC1=CC=CC=C1 COLNVLDHVKWLRT-QMMMGPOBSA-N 0.000 claims 2
- KZSNJWFQEVHDMF-UHFFFAOYSA-N Valine Natural products CC(C)C(N)C(O)=O KZSNJWFQEVHDMF-UHFFFAOYSA-N 0.000 claims 2
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 claims 2
- 230000029087 digestion Effects 0.000 claims 2
- ZDXPYRJPNDTMRX-UHFFFAOYSA-N glutamine Natural products OC(=O)C(N)CCC(N)=O ZDXPYRJPNDTMRX-UHFFFAOYSA-N 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 210000003205 muscle Anatomy 0.000 claims 2
- -1 Ile amino acid Chemical class 0.000 claims 1
- KZSNJWFQEVHDMF-BYPYZUCNSA-N L-valine Chemical compound CC(C)[C@H](N)C(O)=O KZSNJWFQEVHDMF-BYPYZUCNSA-N 0.000 claims 1
- ROHFNLRQFUQHCH-UHFFFAOYSA-N Leucine Natural products CC(C)CC(N)C(O)=O ROHFNLRQFUQHCH-UHFFFAOYSA-N 0.000 claims 1
- 239000004472 Lysine Substances 0.000 claims 1
- AYFVYJQAPQTCCC-UHFFFAOYSA-N Threonine Natural products CC(O)C(N)C(O)=O AYFVYJQAPQTCCC-UHFFFAOYSA-N 0.000 claims 1
- 239000004473 Threonine Substances 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 238000009472 formulation Methods 0.000 claims 1
- 210000004051 gastric juice Anatomy 0.000 claims 1
- HNDVDQJCIGZPNO-UHFFFAOYSA-N histidine Natural products OC(=O)C(N)CC1=CN=CN1 HNDVDQJCIGZPNO-UHFFFAOYSA-N 0.000 claims 1
- AGPKZVBTJJNPAG-UHFFFAOYSA-N isoleucine Natural products CCC(C)C(N)C(O)=O AGPKZVBTJJNPAG-UHFFFAOYSA-N 0.000 claims 1
- 229960000310 isoleucine Drugs 0.000 claims 1
- 235000016709 nutrition Nutrition 0.000 claims 1
- COLNVLDHVKWLRT-UHFFFAOYSA-N phenylalanine Natural products OC(=O)C(N)CC1=CC=CC=C1 COLNVLDHVKWLRT-UHFFFAOYSA-N 0.000 claims 1
- 239000004474 valine Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261728427P | 2012-11-20 | 2012-11-20 | |
| US61/728,427 | 2012-11-20 | ||
| PCT/US2013/071091 WO2014081884A1 (en) | 2012-11-20 | 2013-11-20 | Engineered secreted proteins and methods |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016500250A JP2016500250A (ja) | 2016-01-12 |
| JP2016500250A5 true JP2016500250A5 (https=) | 2017-01-19 |
Family
ID=50776536
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015543148A Withdrawn JP2016500250A (ja) | 2012-11-20 | 2013-11-20 | 改変された分泌タンパク質及び方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20150307562A1 (https=) |
| EP (1) | EP2922416A4 (https=) |
| JP (1) | JP2016500250A (https=) |
| CN (1) | CN104936466A (https=) |
| CA (1) | CA2892021A1 (https=) |
| HK (1) | HK1214739A1 (https=) |
| WO (1) | WO2014081884A1 (https=) |
Families Citing this family (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10689681B2 (en) * | 2013-05-31 | 2020-06-23 | Dsm Ip Assets B.V. | Microorganisms for diterpene production |
| EP3027741B1 (en) | 2013-07-29 | 2019-10-23 | Danisco US Inc. | Gh61 enzyme variants |
| RU2016110800A (ru) | 2013-09-25 | 2017-10-30 | Пронутриа Биосайенсис, Инк. | Составы и композиции для поддержания и увеличения мышечной массы, силы и результативности, и способы их производства и использования |
| GB201401699D0 (en) * | 2014-01-31 | 2014-03-19 | Dupont Nutrition Biosci Aps | Protein |
| CN103881994B (zh) * | 2014-04-14 | 2020-03-27 | 中国农业科学院生物技术研究所 | 一种具有高转糖苷活性的β-半乳糖苷酶突变体及其制备方法和应用 |
| FR3022558B1 (fr) * | 2014-06-20 | 2019-01-25 | Proteus | Variants d'exoglucanases a activite amelioree et leurs utilisations |
| HRP20211601T1 (hr) * | 2014-09-22 | 2022-01-21 | Tanea Medical Ab | Rekombinantni proteini bez fenilalanina (phe) za liječenje fenilketonurije |
| EP3201214A4 (en) * | 2014-10-01 | 2018-04-04 | Ansun Biopharma, Inc. | Ecotin variants |
| WO2016077457A1 (en) | 2014-11-11 | 2016-05-19 | Clara Foods Co. | Methods and compositions for egg white protein production |
| MX383142B (es) | 2014-12-19 | 2025-03-13 | Novozymes As | Composiciones que comprenden polipéptidos que tienen actividad xilanasa y polipéptidos que tienen actividad arabinofuranosidasa. |
| GB201501565D0 (en) * | 2015-01-30 | 2015-03-18 | Dupont Nutrition Biosci Aps | Method |
| US20180243392A1 (en) * | 2015-03-17 | 2018-08-30 | Vanderbilt University | Cs21 and lnga protein vaccines |
| BR112017028063B1 (pt) * | 2015-06-26 | 2022-05-17 | Novozymes A/S | Método para produção de um extrato de café |
| US10188135B2 (en) * | 2015-11-04 | 2019-01-29 | Stokley-Van Camp, Inc. | Method for inducing satiety |
| CN108697773B (zh) | 2016-02-18 | 2022-11-22 | 天野酶制品株式会社 | 肠内菌群改善剂 |
| CN109196098A (zh) * | 2016-05-24 | 2019-01-11 | 诺维信公司 | 包含具有半乳聚糖酶活性的多肽和具有β-半乳糖苷酶活性的多肽的组合物 |
| WO2017202979A1 (en) * | 2016-05-24 | 2017-11-30 | Novozymes A/S | Polypeptides having alpha-galactosidase activity and polynucleotides encoding same |
| US10808268B2 (en) | 2016-05-24 | 2020-10-20 | Novozymes A/S | Polypeptides having alpha-galactosidase activity and polynucleotides encoding same |
| US11273455B2 (en) | 2016-06-27 | 2022-03-15 | Novozymes A/S | Method of dewatering post fermentation fluids |
| CA3029113A1 (en) * | 2016-07-08 | 2018-01-11 | Novozymes A/S | Xylanase variants and polynucleotides encoding same |
| CN109477126B (zh) * | 2016-07-19 | 2023-06-20 | 三得利控股株式会社 | 罗汉果醇或罗汉果醇糖苷的生产方法 |
| MD3290436T2 (ro) | 2016-09-01 | 2019-10-31 | Metax Inst Fur Diatetik Gmbh | Proteină fără fenilalanină pentru tratamentul fenilcetonuriei |
| EA201891926A1 (ru) * | 2017-02-03 | 2019-04-30 | Киверди, Инк. | Микроорганизмы и искусственные экосистемы для производства белка, продуктов питания и полезных побочных продуктов из субстратов c1 |
| BR112019018381A2 (pt) * | 2017-03-06 | 2020-04-07 | Dupont Nutrition Biosci Aps | fucosidases fúngicas e seu uso na prevenção e/ou no tratamento de uma infecção patogênica em um animal |
| JP2021534763A (ja) * | 2018-08-21 | 2021-12-16 | クララ フーズ カンパニー | 微生物におけるタンパク質のグリコシル化の修飾 |
| CN113302298B (zh) | 2018-11-09 | 2025-02-25 | 银杏生物制品公司 | 罗汉果甙的生物合成 |
| EP3941931A1 (en) * | 2019-03-19 | 2022-01-26 | Bayer CropScience LP | Fusion proteins, recombinant bacteria, and exosporium fragments for plant health |
| KR20220034848A (ko) | 2019-07-11 | 2022-03-18 | 클라라 푸드즈 컴퍼니 | 단백질 조성물 및 이의 섭취 가능한 제품 |
| US12096784B2 (en) | 2019-07-11 | 2024-09-24 | Clara Foods Co. | Protein compositions and consumable products thereof |
| US10927360B1 (en) | 2019-08-07 | 2021-02-23 | Clara Foods Co. | Compositions comprising digestive enzymes |
| EP4031661A1 (en) | 2019-09-16 | 2022-07-27 | Novozymes A/S | Polypeptides having beta-glucanase activity and polynucleotides encoding same |
| EP3892290A1 (en) * | 2020-04-08 | 2021-10-13 | NUMAFERM GmbH | Variants of hlya and uses thereof |
| EP4121086A1 (en) * | 2020-03-18 | 2023-01-25 | NUMAFERM GmbH | Variants of hlya and uses thereof |
| WO2021207679A1 (en) * | 2020-04-10 | 2021-10-14 | Liberty Biosecurity, Llc | Polypeptide compositions and uses thereof |
| CA3198703A1 (en) * | 2020-11-13 | 2022-05-19 | Timothy GEISTLINGER | Methods and compositions for producing recombinant components for use in food and other products |
| WO2022173694A1 (en) * | 2021-02-10 | 2022-08-18 | Novozymes A/S | Polypeptides having pectinase activity, polynucleotides encoding same, and uses thereof |
| EP4314242A4 (en) * | 2021-03-25 | 2025-01-22 | Bio-Cat, Inc. | MIXTURES OF FUNGAL PROTEASES AND THEIR USES |
| CN114015678A (zh) * | 2021-09-30 | 2022-02-08 | 中南民族大学 | 一种球形赖氨酸芽孢杆菌C3-41来源的氨肽酶Amp0279及其重组菌株和应用 |
| MX2021014268A (es) * | 2021-11-19 | 2022-02-16 | Univ Mexico Nac Autonoma | Proteina optimizada que comprende los aminoacidos esenciales para la nutricion humana. |
| WO2023168396A2 (en) * | 2022-03-04 | 2023-09-07 | Cella Farms Inc. | Computational system and algorithm for selecting nutritional microorganisms based on in silico protein quality determination |
| EP4511501A1 (en) | 2022-04-20 | 2025-02-26 | Novozymes A/S | Process for producing free fatty acids |
| WO2023215798A1 (en) * | 2022-05-04 | 2023-11-09 | Locus Biosciences, Inc. | Phage compositions for escherichia comprising crispr-cas systems and methods of use thereof |
| EP4525615A2 (en) | 2022-05-14 | 2025-03-26 | Novozymes A/S | Compositions and methods for preventing, treating, supressing and/or eliminating phytopathogenic infestations and infections |
| CN115160420B (zh) * | 2022-06-24 | 2023-06-02 | 西南大学 | 盔形毕赤酵母scp类分泌蛋白及其应用 |
| WO2024220717A1 (en) * | 2023-04-20 | 2024-10-24 | Ginkgo Bioworks, Inc. | Biosynthesis of mogrosides |
| WO2025155915A1 (en) * | 2024-01-17 | 2025-07-24 | Anagram Therapeutics, Inc. | Methods and compositions for treating congenital sucrase-isomaltase deficiency |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6800726B1 (en) * | 1996-11-01 | 2004-10-05 | Pioneer Hi-Bred International, Inc. | Proteins with increased levels of essential amino acids |
| AR017831A1 (es) * | 1997-12-10 | 2001-10-24 | Pioneer Hi Bred Int | Metodo para alterar la composicion de aminoacidos de una proteina nativa de interes, proteina elaborada, y polinucleotido |
| US20060159724A1 (en) * | 2000-08-08 | 2006-07-20 | Bell Stacey J | Nutritional supplement for the management of weight |
| WO2003025153A2 (en) * | 2001-09-17 | 2003-03-27 | Monsanto Technology, Llc | Enhanced proteins and methods for their use |
| US7273738B2 (en) * | 2002-10-01 | 2007-09-25 | Novozymes A/S | Family GH-61 polypeptides |
| CN1557475A (zh) * | 2004-02-04 | 2004-12-29 | 高春平 | 美容、减肥营养组合物 |
| EP2327316B1 (en) * | 2009-11-29 | 2016-11-16 | Premier Nutrition Corporation | Method of enhancing muscle protein synthesis |
| MX2012007681A (es) * | 2009-12-31 | 2013-01-29 | Pioneer Hi Bred Int | Ingenieria de resistencia de plantas a enfermedades causadas por patogenos. |
| EP2703484A4 (en) * | 2011-03-24 | 2014-12-31 | Asahi Glass Co Ltd | TRANSFORMANT FROM YEAST OF ART SCHIZOSACCHAROMYCES, METHOD OF MANUFACTURING THEREOF, PROCESS FOR THE PREPARATION OF BETA-GLUCOSIDASE AND METHOD FOR THE DECOMPOSITION OF CELLULOSE |
| EP2831098A4 (en) * | 2012-03-26 | 2016-12-07 | Axcella Health Inc | LOADED NUTRIENT PROTEINS AND METHODS |
-
2013
- 2013-11-20 HK HK16102843.7A patent/HK1214739A1/zh unknown
- 2013-11-20 CA CA2892021A patent/CA2892021A1/en not_active Abandoned
- 2013-11-20 JP JP2015543148A patent/JP2016500250A/ja not_active Withdrawn
- 2013-11-20 CN CN201380070852.1A patent/CN104936466A/zh active Pending
- 2013-11-20 US US14/443,773 patent/US20150307562A1/en not_active Abandoned
- 2013-11-20 WO PCT/US2013/071091 patent/WO2014081884A1/en not_active Ceased
- 2013-11-20 EP EP13856957.9A patent/EP2922416A4/en not_active Withdrawn
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