JP2016169388A5 - - Google Patents
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- Publication number
- JP2016169388A5 JP2016169388A5 JP2016086958A JP2016086958A JP2016169388A5 JP 2016169388 A5 JP2016169388 A5 JP 2016169388A5 JP 2016086958 A JP2016086958 A JP 2016086958A JP 2016086958 A JP2016086958 A JP 2016086958A JP 2016169388 A5 JP2016169388 A5 JP 2016169388A5
- Authority
- JP
- Japan
- Prior art keywords
- alkylene
- group
- amine
- amine polymer
- polymer according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 125000002947 alkylene group Chemical group 0.000 claims 23
- 150000001412 amines Chemical class 0.000 claims 23
- RAXXELZNTBOGNW-UHFFFAOYSA-N imidazole Natural products C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 claims 18
- 229920000642 polymer Polymers 0.000 claims 16
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims 10
- 125000000753 cycloalkyl group Chemical group 0.000 claims 10
- 239000000178 monomer Substances 0.000 claims 7
- 150000001408 amides Chemical class 0.000 claims 5
- 125000003118 aryl group Chemical group 0.000 claims 5
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 claims 5
- 150000002148 esters Chemical class 0.000 claims 5
- 125000000524 functional group Chemical group 0.000 claims 5
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 4
- 229910052739 hydrogen Inorganic materials 0.000 claims 4
- 239000001257 hydrogen Substances 0.000 claims 4
- RZTDESRVPFKCBH-UHFFFAOYSA-N 1-methyl-4-(4-methylphenyl)benzene Chemical group C1=CC(C)=CC=C1C1=CC=C(C)C=C1 RZTDESRVPFKCBH-UHFFFAOYSA-N 0.000 claims 3
- 125000000732 arylene group Chemical group 0.000 claims 3
- 125000003545 alkoxy group Chemical group 0.000 claims 2
- 125000000217 alkyl group Chemical group 0.000 claims 2
- 125000004104 aryloxy group Chemical group 0.000 claims 2
- 125000001475 halogen functional group Chemical group 0.000 claims 2
- 125000004356 hydroxy functional group Chemical group O* 0.000 claims 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 2
- 238000006116 polymerization reaction Methods 0.000 claims 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 238000008214 LDL Cholesterol Methods 0.000 claims 1
- 238000006243 chemical reaction Methods 0.000 claims 1
- 238000004132 cross linking Methods 0.000 claims 1
- 210000002966 serum Anatomy 0.000 claims 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30781910P | 2010-02-24 | 2010-02-24 | |
| US30781610P | 2010-02-24 | 2010-02-24 | |
| US61/307,816 | 2010-02-24 | ||
| US61/307,819 | 2010-02-24 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012555154A Division JP5964247B2 (ja) | 2010-02-24 | 2011-02-24 | 胆汁酸捕捉剤として使用するためのポリイミダゾール |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017040404A Division JP2017101258A (ja) | 2010-02-24 | 2017-03-03 | 胆汁酸捕捉剤として使用するためのポリイミダゾール |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016169388A JP2016169388A (ja) | 2016-09-23 |
| JP2016169388A5 true JP2016169388A5 (enExample) | 2016-11-04 |
| JP6431499B2 JP6431499B2 (ja) | 2018-11-28 |
Family
ID=43975199
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012555154A Expired - Fee Related JP5964247B2 (ja) | 2010-02-24 | 2011-02-24 | 胆汁酸捕捉剤として使用するためのポリイミダゾール |
| JP2016086958A Expired - Fee Related JP6431499B2 (ja) | 2010-02-24 | 2016-04-25 | 胆汁酸捕捉剤として使用するためのポリイミダゾール |
| JP2017040404A Withdrawn JP2017101258A (ja) | 2010-02-24 | 2017-03-03 | 胆汁酸捕捉剤として使用するためのポリイミダゾール |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012555154A Expired - Fee Related JP5964247B2 (ja) | 2010-02-24 | 2011-02-24 | 胆汁酸捕捉剤として使用するためのポリイミダゾール |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017040404A Withdrawn JP2017101258A (ja) | 2010-02-24 | 2017-03-03 | 胆汁酸捕捉剤として使用するためのポリイミダゾール |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20130189215A1 (enExample) |
| EP (2) | EP3130343B1 (enExample) |
| JP (3) | JP5964247B2 (enExample) |
| CN (2) | CN106478948B (enExample) |
| AU (2) | AU2011220745B2 (enExample) |
| BR (1) | BR112012021448A2 (enExample) |
| CA (1) | CA2790899C (enExample) |
| ES (1) | ES2598500T3 (enExample) |
| GB (1) | GB2490853B (enExample) |
| WO (1) | WO2011106545A1 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2661079T3 (es) | 2010-02-24 | 2018-03-27 | Relypsa, Inc. | Polímeros de amina para su uso como secuestrantes de ácidos biliares |
| EP2539380B1 (en) | 2010-02-24 | 2015-08-19 | Relypsa, Inc. | Crosslinked polyvinylamine, polyallylamine, and polyethyleneimine for use as bile acid sequestrants |
| US20130244234A1 (en) * | 2012-01-23 | 2013-09-19 | Glc Biotechnology, Inc. | Stool collection methods for analysis of dna in stool |
| WO2014034871A1 (ja) * | 2012-08-30 | 2014-03-06 | 株式会社 三和化学研究所 | 脂質異常症の予防又は治療薬 |
| CN111671766B (zh) | 2013-06-05 | 2024-03-08 | 特里赛达公司 | 用于口服施用的结合质子的聚合物 |
| EP3131920B1 (en) | 2014-04-16 | 2021-09-01 | The UAB Research Foundation | Msp nanopores and uses thereof |
| AU2015274377B2 (en) | 2014-06-13 | 2020-07-23 | United Therapeutics Corporation | Treprostinil formulations |
| RU2020102937A (ru) | 2014-12-10 | 2020-02-13 | Трисида, Инк. | Протон-связывающие полимеры для перорального введения |
| MA41202A (fr) | 2014-12-18 | 2017-10-24 | Genzyme Corp | Copolymères polydiallymine réticulé pour le traitement du diabète de type 2 |
| EP3331499A4 (en) * | 2015-08-06 | 2019-04-10 | The Johns Hopkins University | COMPOSITION AND METHOD FOR THE TREATMENT OF METABOLISM DISEASES |
| CN106967217A (zh) * | 2016-01-14 | 2017-07-21 | 华南理工大学 | 聚咪唑类化合物及其原位制备方法和应用 |
| EP3452028A4 (en) | 2016-05-06 | 2020-04-15 | Tricida Inc. | COMPOSITIONS AND METHOD FOR TREATING ACID-BASED DISORDERS |
| EP3564292B1 (en) | 2016-12-28 | 2021-06-16 | FUJIFILM Corporation | Emulsion of nitrogen atom-containing polymer or salt thereof, production method therefor, and production method for particles |
| CN111225674A (zh) | 2017-10-16 | 2020-06-02 | 富士胶片株式会社 | 高磷血症治疗剂 |
| IL273960B2 (en) | 2017-11-03 | 2025-08-01 | Tricida Inc | Nonabsorable compositions for use in treating or preventing metabolic acidosis |
| CN109932349B (zh) * | 2019-04-04 | 2021-04-20 | 济南大学 | 一种检测次氯酸的有机硅小分子荧光探针 |
| WO2021040440A1 (ko) * | 2019-08-30 | 2021-03-04 | (주)셀트리온 | 비알콜성 지방간염(nash, nonalcoholic steatohepatitis) 치료 또는 예방을 위한 약학 조성물 |
| JP2022548699A (ja) | 2019-09-20 | 2022-11-21 | グライセンド， インコーポレイテッド | 置換フェニルボロン酸含有ポリマーおよび使用方法 |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60209523A (ja) * | 1984-04-03 | 1985-10-22 | Mitsubishi Petrochem Co Ltd | コレステロ−ル低下剤 |
| US4649048A (en) * | 1984-05-11 | 1987-03-10 | Bristol-Myers Company | Novel bile sequestrant resin |
| US4600578A (en) * | 1984-05-11 | 1986-07-15 | Bristol-Myers Company | Method of inhibiting diarrhea |
| ATE130193T1 (de) * | 1992-03-28 | 1995-12-15 | Hoechst Ag | Arzneimittel aus polyhydroxymethylenderivaten, verfahren zu deren herstellung und verwendung. |
| JPH066667A (ja) | 1992-06-22 | 1994-01-14 | Canon Inc | ぶれ検出装置及びぶれ補正装置 |
| US5631365A (en) | 1993-09-21 | 1997-05-20 | Schering Corporation | Hydroxy-substituted azetidinone compounds useful as hypocholesterolemic agents |
| US5414068A (en) | 1994-01-24 | 1995-05-09 | Rohm And Haas Company | Crosslinked anion exchange particles and method for producing the particles |
| CN1189168A (zh) * | 1995-06-06 | 1998-07-29 | 吉尔特药品公司 | 用于清除胆固醇的含疏水杂原子的螯合剂 |
| JP4156684B2 (ja) * | 1996-03-05 | 2008-09-24 | 三菱化学株式会社 | 高リン血症予防および／または治療剤 |
| CZ301055B6 (cs) * | 1997-09-15 | 2009-10-29 | The Procter & Gamble Company | Prací detergentní prostredky s polymery na bázi celulosy prospívající vzhledu a celistvosti tkanin, které jsou v nich vyprány |
| US6147183A (en) * | 1997-09-15 | 2000-11-14 | Basf Aktiengesellschaft | Amphoteric amine based polymers having a net cationic charge and process for their production |
| US5900233A (en) * | 1997-10-16 | 1999-05-04 | Day; Charles E. | Epichlorohydrin and 1-(3-aminopropyl) imidazole copolymer and its use in treating irritable bowel syndrome |
| AU1101700A (en) * | 1998-10-13 | 2000-05-01 | Procter & Gamble Company, The | Laundry detergent compositions with a combination of cyclic amine based polymersand hydrophobically modified carboxy methyl cellulose |
| US6472364B1 (en) * | 1998-10-13 | 2002-10-29 | The Procter & Gamble Company | Detergent compositions or components |
| AU1906500A (en) * | 1999-10-29 | 2001-05-14 | Procter & Gamble Company, The | Laundry detergent compositions with fabric care |
| JP2002068985A (ja) * | 2000-08-30 | 2002-03-08 | Mitsubishi-Tokyo Pharmaceuticals Inc | 薬剤性肝障害治療薬 |
| CN100594933C (zh) * | 2000-11-28 | 2010-03-24 | 田边三菱制药株式会社 | 抗肥胖剂和健康食品 |
| EP1413309B1 (en) * | 2001-07-30 | 2007-11-14 | Mitsubishi Pharma Corporation | Drugs for ameliorating postcibal hyperglycemia |
| JP2003113091A (ja) * | 2001-10-02 | 2003-04-18 | Sekisui Chem Co Ltd | 胆汁酸特異的認識ポリマー及びコレステロール低下剤 |
| US7608674B2 (en) * | 2003-11-03 | 2009-10-27 | Ilypsa, Inc. | Pharmaceutical compositions comprising cross-linked small molecule amine polymers |
| US7459502B2 (en) * | 2003-11-03 | 2008-12-02 | Ilypsa, Inc. | Pharmaceutical compositions comprising crosslinked polyamine polymers |
| US7470705B2 (en) * | 2004-03-26 | 2008-12-30 | Eli Lilly And Company | Compounds and methods for treating dyslipidemia |
| JP4896480B2 (ja) * | 2004-10-01 | 2012-03-14 | 第一三共ヘルスケア株式会社 | 陰イオン交換樹脂の粒子状組成物 |
| JP6218355B2 (ja) * | 2011-02-10 | 2017-10-25 | ソニー株式会社 | 濾材 |
| CN105900233A (zh) * | 2013-12-13 | 2016-08-24 | Wow研究中心有限公司 | 半导体装置及其制造方法 |
| CN106147183A (zh) * | 2015-04-01 | 2016-11-23 | 合肥杰事杰新材料股份有限公司 | 一种pc/abs合金材料及其制备方法 |
-
2011
- 2011-02-24 CA CA2790899A patent/CA2790899C/en not_active Expired - Fee Related
- 2011-02-24 ES ES11707039.1T patent/ES2598500T3/es active Active
- 2011-02-24 EP EP16184141.6A patent/EP3130343B1/en not_active Not-in-force
- 2011-02-24 WO PCT/US2011/026102 patent/WO2011106545A1/en not_active Ceased
- 2011-02-24 BR BR112012021448A patent/BR112012021448A2/pt not_active Application Discontinuation
- 2011-02-24 EP EP11707039.1A patent/EP2538947B1/en not_active Not-in-force
- 2011-02-24 CN CN201610881008.2A patent/CN106478948B/zh not_active Expired - Fee Related
- 2011-02-24 JP JP2012555154A patent/JP5964247B2/ja not_active Expired - Fee Related
- 2011-02-24 GB GB1216799.5A patent/GB2490853B/en not_active Expired - Fee Related
- 2011-02-24 AU AU2011220745A patent/AU2011220745B2/en not_active Ceased
- 2011-02-24 CN CN201180020473.2A patent/CN102858347B/zh not_active Expired - Fee Related
- 2011-02-24 US US13/581,102 patent/US20130189215A1/en not_active Abandoned
-
2016
- 2016-04-25 JP JP2016086958A patent/JP6431499B2/ja not_active Expired - Fee Related
-
2017
- 2017-02-24 AU AU2017201276A patent/AU2017201276B2/en not_active Ceased
- 2017-03-03 JP JP2017040404A patent/JP2017101258A/ja not_active Withdrawn
-
2019
- 2019-02-08 US US16/271,296 patent/US20190169342A1/en not_active Abandoned
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