JP2015535834A5 - - Google Patents
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- Publication number
- JP2015535834A5 JP2015535834A5 JP2015533561A JP2015533561A JP2015535834A5 JP 2015535834 A5 JP2015535834 A5 JP 2015535834A5 JP 2015533561 A JP2015533561 A JP 2015533561A JP 2015533561 A JP2015533561 A JP 2015533561A JP 2015535834 A5 JP2015535834 A5 JP 2015535834A5
- Authority
- JP
- Japan
- Prior art keywords
- substituted
- unsubstituted
- alkyl
- different
- alkylsilyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- -1 substituted Chemical class 0.000 claims 67
- 125000000623 heterocyclic group Chemical group 0.000 claims 41
- 125000005103 alkyl silyl group Chemical group 0.000 claims 27
- 229910052736 halogen Inorganic materials 0.000 claims 27
- 150000002367 halogens Chemical class 0.000 claims 27
- 229910052739 hydrogen Inorganic materials 0.000 claims 27
- 239000001257 hydrogen Substances 0.000 claims 26
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims 23
- 125000004649 C2-C8 alkynyl group Chemical group 0.000 claims 16
- 125000005842 heteroatom Chemical group 0.000 claims 16
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 15
- 229910052799 carbon Inorganic materials 0.000 claims 15
- 125000004432 carbon atom Chemical group C* 0.000 claims 15
- 125000003118 aryl group Chemical group 0.000 claims 14
- NHFDIUPJVYYTLG-UHFFFAOYSA-N carbononitridic isocyanide Chemical compound [C-]#[N+]C#N NHFDIUPJVYYTLG-UHFFFAOYSA-N 0.000 claims 14
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 12
- 125000005017 substituted alkenyl group Chemical group 0.000 claims 12
- 125000004093 cyano group Chemical group *C#N 0.000 claims 11
- 150000002431 hydrogen Chemical class 0.000 claims 9
- 150000001875 compounds Chemical class 0.000 claims 8
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 8
- 125000004648 C2-C8 alkenyl group Chemical group 0.000 claims 7
- KXDHJXZQYSOELW-UHFFFAOYSA-M Carbamate Chemical compound NC([O-])=O KXDHJXZQYSOELW-UHFFFAOYSA-M 0.000 claims 6
- 125000001769 aryl amino group Chemical group 0.000 claims 6
- 125000005163 aryl sulfanyl group Chemical group 0.000 claims 6
- 125000004104 aryloxy group Chemical group 0.000 claims 6
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 claims 6
- 125000002485 formyl group Chemical group [H]C(*)=O 0.000 claims 6
- 125000001475 halogen functional group Chemical group 0.000 claims 6
- 125000003396 thiol group Chemical group [H]S* 0.000 claims 6
- 241001481833 Coryphaena hippurus Species 0.000 claims 5
- 241000233866 Fungi Species 0.000 claims 5
- 125000005018 aryl alkenyl group Chemical group 0.000 claims 5
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 5
- 125000005292 haloalkynyloxy group Chemical group 0.000 claims 5
- 125000005347 halocycloalkyl group Chemical group 0.000 claims 5
- 244000005700 microbiome Species 0.000 claims 5
- 230000003032 phytopathogenic effect Effects 0.000 claims 5
- 125000005122 aminoalkylamino group Chemical group 0.000 claims 4
- 238000000034 method Methods 0.000 claims 4
- 150000003839 salts Chemical class 0.000 claims 4
- 229910052717 sulfur Inorganic materials 0.000 claims 4
- 125000004430 oxygen atom Chemical group O* 0.000 claims 3
- 125000004434 sulfur atom Chemical group 0.000 claims 3
- FNJPMIYMKZBZCC-UHFFFAOYSA-N 4,5-dihydro-1,2-oxazole quinoline Chemical class C1CC=NO1.N1=CC=CC2=CC=CC=C21 FNJPMIYMKZBZCC-UHFFFAOYSA-N 0.000 claims 2
- 125000001054 5 membered carbocyclic group Chemical group 0.000 claims 2
- 125000004008 6 membered carbocyclic group Chemical group 0.000 claims 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims 2
- 125000003302 alkenyloxy group Chemical group 0.000 claims 2
- 125000005133 alkynyloxy group Chemical group 0.000 claims 2
- 125000002147 dimethylamino group Chemical group [H]C([H])([H])N(*)C([H])([H])[H] 0.000 claims 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 2
- 125000005647 linker group Chemical group 0.000 claims 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 2
- 125000005346 substituted cycloalkyl group Chemical group 0.000 claims 2
- 239000004094 surface-active agent Substances 0.000 claims 2
- 230000009261 transgenic effect Effects 0.000 claims 2
- XMCAJYZIJTWANG-HUQDXCLPSA-N (1R,2R)-4-(dimethylamino)-1-[6-[(E)-hydroxyiminomethyl]-2-methoxyquinolin-3-yl]-2-naphthalen-1-yl-1-phenylbutan-2-ol Chemical compound CN(CC[C@]([C@H](C1=CC=CC=C1)C=1C(=NC2=CC=C(C=C2C1)/C=N/O)OC)(O)C1=CC=CC2=CC=CC=C12)C XMCAJYZIJTWANG-HUQDXCLPSA-N 0.000 claims 1
- MRFPRJAZMYOHJW-MKCMJLOXSA-N (1R,2R)-6-(dimethylamino)-1-[6-[(E)-hydroxyiminomethyl]-2-methoxyquinolin-3-yl]-2-naphthalen-2-yl-1-phenylhexan-2-ol Chemical compound CN(CCCC[C@]([C@H](C1=CC=CC=C1)C=1C(=NC2=CC=C(C=C2C1)/C=N/O)OC)(O)C1=CC2=CC=CC=C2C=C1)C MRFPRJAZMYOHJW-MKCMJLOXSA-N 0.000 claims 1
- XMCAJYZIJTWANG-BABVVNGDSA-N (1R,2S)-4-(dimethylamino)-1-[6-[(E)-hydroxyiminomethyl]-2-methoxyquinolin-3-yl]-2-naphthalen-1-yl-1-phenylbutan-2-ol Chemical compound CN(CC[C@@]([C@H](C1=CC=CC=C1)C=1C(=NC2=CC=C(C=C2C1)/C=N/O)OC)(O)C1=CC=CC2=CC=CC=C12)C XMCAJYZIJTWANG-BABVVNGDSA-N 0.000 claims 1
- MRFPRJAZMYOHJW-YHJIWIJTSA-N (1R,2S)-6-(dimethylamino)-1-[6-[(E)-hydroxyiminomethyl]-2-methoxyquinolin-3-yl]-2-naphthalen-2-yl-1-phenylhexan-2-ol Chemical compound CN(CCCC[C@@]([C@H](C1=CC=CC=C1)C=1C(=NC2=CC=C(C=C2C1)/C=N/O)OC)(O)C1=CC2=CC=CC=C2C=C1)C MRFPRJAZMYOHJW-YHJIWIJTSA-N 0.000 claims 1
- SBEPSOQMHPACTJ-HPMWZEIGSA-N (5R,6S)-6-[(1R)-1-hydroxyethyl]-3-[2-[(E)-hydroxyiminomethyl]phenanthridin-8-yl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid Chemical compound O[C@H](C)[C@@H]1[C@H]2CC(=C(N2C1=O)C(=O)O)C1=CC2=CN=C3C=CC(=CC3=C2C=C1)/C=N/O SBEPSOQMHPACTJ-HPMWZEIGSA-N 0.000 claims 1
- DWAZFYIKSQOJPD-WUXMJOGZSA-N (NE)-N-[(5-nitroquinolin-6-yl)methylidene]hydroxylamine Chemical compound [O-][N+](=O)c1c(/C=N/O)ccc2ncccc21 DWAZFYIKSQOJPD-WUXMJOGZSA-N 0.000 claims 1
- DWAZFYIKSQOJPD-SDQBBNPISA-N (NZ)-N-[(5-nitroquinolin-6-yl)methylidene]hydroxylamine Chemical compound [O-][N+](=O)c1c(\C=N/O)ccc2ncccc21 DWAZFYIKSQOJPD-SDQBBNPISA-N 0.000 claims 1
- OPQQWAGBFJQALJ-KPKJPENVSA-N (ne)-n-(quinolin-6-ylmethylidene)hydroxylamine Chemical compound N1=CC=CC2=CC(/C=N/O)=CC=C21 OPQQWAGBFJQALJ-KPKJPENVSA-N 0.000 claims 1
- LIORMTVHNLXADF-AWNIVKPZSA-N (ne)-n-[(5-aminoquinolin-6-yl)methylidene]hydroxylamine Chemical compound C1=CC=C2C(N)=C(\C=N\O)C=CC2=N1 LIORMTVHNLXADF-AWNIVKPZSA-N 0.000 claims 1
- QEPYTBPNSWTPJK-UHFFFAOYSA-N 4,5-dihydro-1,2-oxazole-5-carbothioic S-acid quinoline Chemical compound SC(=O)C1CC=NO1.c1ccc2ncccc2c1 QEPYTBPNSWTPJK-UHFFFAOYSA-N 0.000 claims 1
- LDTYZQPHTJSMGY-UHFFFAOYSA-N 4,5-dihydro-1,2-oxazole-5-carboxylic acid quinoline Chemical compound O1N=CCC1C(=O)O.N1=CC=CC2=CC=CC=C12 LDTYZQPHTJSMGY-UHFFFAOYSA-N 0.000 claims 1
- 239000004606 Fillers/Extenders Substances 0.000 claims 1
- DIMCRNMCHZWYNQ-UHFFFAOYSA-N N-hydroxyquinoline-6-carboximidoyl chloride Chemical compound ON=C(Cl)c1ccc2ncccc2c1 DIMCRNMCHZWYNQ-UHFFFAOYSA-N 0.000 claims 1
- TYEZCLFGKKCDTG-UHFFFAOYSA-N N-hydroxyquinoline-6-carboximidoyl chloride hydrochloride Chemical compound Cl.ON=C(Cl)c1ccc2ncccc2c1 TYEZCLFGKKCDTG-UHFFFAOYSA-N 0.000 claims 1
- 150000001204 N-oxides Chemical class 0.000 claims 1
- XDZGUHUIWVRDMX-HVYLCQPDSA-N [Na].O[C@H](C)[C@@H]1[C@H]2CC(=C(N2C1=O)C(=O)O)C1=CC2=CN=C3C=CC(=CC3=C2C=C1)/C=N/O Chemical compound [Na].O[C@H](C)[C@@H]1[C@H]2CC(=C(N2C1=O)C(=O)O)C1=CC2=CN=C3C=CC(=CC3=C2C=C1)/C=N/O XDZGUHUIWVRDMX-HVYLCQPDSA-N 0.000 claims 1
- 230000000895 acaricidal effect Effects 0.000 claims 1
- 239000000642 acaricide Substances 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- 239000004480 active ingredient Substances 0.000 claims 1
- 125000003342 alkenyl group Chemical group 0.000 claims 1
- 125000004644 alkyl sulfinyl group Chemical group 0.000 claims 1
- 125000004414 alkyl thio group Chemical group 0.000 claims 1
- 125000000304 alkynyl group Chemical group 0.000 claims 1
- 230000000844 anti-bacterial effect Effects 0.000 claims 1
- 239000005667 attractant Substances 0.000 claims 1
- 239000003899 bactericide agent Substances 0.000 claims 1
- 239000004067 bulking agent Substances 0.000 claims 1
- 150000001733 carboxylic acid esters Chemical class 0.000 claims 1
- 150000002148 esters Chemical class 0.000 claims 1
- 239000002871 fertility agent Substances 0.000 claims 1
- 239000003337 fertilizer Substances 0.000 claims 1
- 239000000417 fungicide Substances 0.000 claims 1
- 239000003630 growth substance Substances 0.000 claims 1
- 125000004439 haloalkylsulfanyl group Chemical group 0.000 claims 1
- 239000004009 herbicide Substances 0.000 claims 1
- 239000002917 insecticide Substances 0.000 claims 1
- 150000002527 isonitriles Chemical group 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000005645 nematicide Substances 0.000 claims 1
- 229910052757 nitrogen Inorganic materials 0.000 claims 1
- 229910052760 oxygen Inorganic materials 0.000 claims 1
- 125000004548 quinolin-3-yl group Chemical group N1=CC(=CC2=CC=CC=C12)* 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 125000000547 substituted alkyl group Chemical group 0.000 claims 1
- 125000003107 substituted aryl group Chemical group 0.000 claims 1
- 0 CC1(*)C(c2c(*)c(*)c3nc(*)c(*)c(*)c3c2*)=NOC1(C)C(N(*)**)=* Chemical compound CC1(*)C(c2c(*)c(*)c3nc(*)c(*)c(*)c3c2*)=NOC1(C)C(N(*)**)=* 0.000 description 5
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12186485 | 2012-09-28 | ||
| EP12186485.4 | 2012-09-28 | ||
| PCT/EP2013/069893 WO2014048940A2 (en) | 2012-09-28 | 2013-09-25 | Nitrogen-containing heterocyclic compounds for plant disease control |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015535834A JP2015535834A (ja) | 2015-12-17 |
| JP2015535834A5 true JP2015535834A5 (https=) | 2016-06-23 |
| JP6118907B2 JP6118907B2 (ja) | 2017-04-19 |
Family
ID=47048991
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015533561A Active JP6118907B2 (ja) | 2012-09-28 | 2013-09-25 | 植物病害を防除するための窒素含有ヘテロ環式化合物 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US9510598B2 (https=) |
| EP (1) | EP2900661B1 (https=) |
| JP (1) | JP6118907B2 (https=) |
| CN (1) | CN104812751B (https=) |
| AR (1) | AR092727A1 (https=) |
| BR (1) | BR112015007159A2 (https=) |
| TW (1) | TWI579281B (https=) |
| WO (1) | WO2014048940A2 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5976837B2 (ja) * | 2011-12-29 | 2016-08-24 | バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングＢａｙｅｒ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ ＧｍｂＨ | 殺菌性３−［（１，３−チアゾール−４−イルメトキシイミノ）（フェニル）メチル］−２−置換−１，２，４−オキサジアゾール−５（２ｈ）−オン誘導体 |
| JP2017095353A (ja) * | 2014-03-27 | 2017-06-01 | 日本曹達株式会社 | イソオキサゾリン−５−カルボキサミド化合物および有害生物防除剤 |
| CN105753853B (zh) | 2014-12-16 | 2020-08-04 | 沈阳中化农药化工研发有限公司 | 一种含异恶唑啉的脲嘧啶类化合物及其用途 |
| CN110799511B (zh) | 2017-06-13 | 2023-09-01 | 拜耳公司 | 除草活性的四氢和二氢呋喃甲酰胺的3-苯基异噁唑啉-5-甲酰胺 |
| WO2018228985A1 (de) | 2017-06-13 | 2018-12-20 | Bayer Aktiengesellschaft | Herbizid wirksame 3-phenylisoxazolin-5-carboxamide von tetrahydro- und dihydrofurancarbonsäuren und -estern |
| CN111164077B (zh) * | 2017-08-17 | 2023-12-19 | 拜耳公司 | 除草活性的环戊基羧酸和其酯的3-苯基-5-三氟甲基异噁唑啉-5-甲酰胺 |
| EA202091774A1 (ru) | 2018-01-25 | 2020-12-07 | Байер Акциенгезельшафт | Гербицидно-активные 3-фенилизоксазолин-5-карбоксамиды производных циклопентенилкарбоновой кислоты |
| CN108913698B (zh) * | 2018-07-25 | 2021-10-26 | 安徽农业大学 | 一种与小麦穗发芽抗性/感性相关的caps标记及其应用 |
| CA3133025A1 (en) | 2019-03-12 | 2020-09-17 | Bayer Aktiengesellschaft | Herbicidally active 3-phenylisoxazoline-5-carboxamides of s-containing cyclopentenyl carboxylic acid esters |
| JP2022529973A (ja) * | 2019-04-19 | 2022-06-27 | エルジー・ケム・リミテッド | カスパーゼ阻害剤のプロドラッグ |
| EP3970699A4 (en) * | 2019-05-31 | 2022-08-10 | LG Chem, Ltd. | COMPOSITION FOR CASPASE INHIBITOR PRODRUG INJECTION |
| CN115515962B (zh) * | 2020-05-05 | 2025-04-29 | 巴斯夫欧洲公司 | 稠合异噁唑啉衍生物及其作为除草剂的用途 |
| WO2022128746A1 (en) | 2020-12-14 | 2022-06-23 | Elanco Tiergesundheit Ag | Quinoline derivatives as endoparasiticides |
| KR102636905B1 (ko) | 2021-09-15 | 2024-02-15 | 한국화학연구원 | 살균제로서의 7번 위치가 치환된 5-니트로 퀴놀린 화합물 |
| CN120794925A (zh) * | 2024-04-10 | 2025-10-17 | 青岛清原化合物有限公司 | 3-苯基异噁唑啉-5-甲酰胺类化合物及其制备方法、除草组合物和应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1369233A (en) * | 1971-04-15 | 1974-10-02 | Science Union & Cie | Thiohydroxamic acid derivatives and processes for preparing them |
| CN1642580B (zh) * | 2002-03-29 | 2010-05-26 | 詹森药业有限公司 | 放射性标记的喹啉和喹啉酮衍生物及其作为代谢性谷氨酸受体配体的制造用途 |
| WO2006090234A1 (en) * | 2005-02-22 | 2006-08-31 | Ranbaxy Laboratories Limited | Heterocyclic derivatives as cell adhesion inhibitors |
| KR100774999B1 (ko) * | 2005-02-26 | 2007-11-09 | 주식회사 엘지생명과학 | 이소옥사졸린 유도체 및 그의 제조 방법 |
| CA2668210C (en) * | 2006-10-31 | 2013-03-12 | Schering Corporation | Anilinopiperazine derivatives and methods of use thereof |
| JP2009286773A (ja) * | 2008-03-14 | 2009-12-10 | Bayer Cropscience Ag | 殺虫性縮環式アリール類 |
| EP2394995B1 (en) * | 2009-02-03 | 2014-01-15 | Kumiai Chemical Industry CO., LTD. | Ring-fused 2-pyridone derivatives and herbicides |
| JP2011098956A (ja) * | 2009-10-09 | 2011-05-19 | Sumitomo Chemical Co Ltd | イソオキサゾリン化合物及びその用途 |
-
2013
- 2013-09-25 EP EP13766959.4A patent/EP2900661B1/en not_active Not-in-force
- 2013-09-25 BR BR112015007159A patent/BR112015007159A2/pt active Search and Examination
- 2013-09-25 CN CN201380061985.2A patent/CN104812751B/zh not_active Expired - Fee Related
- 2013-09-25 WO PCT/EP2013/069893 patent/WO2014048940A2/en not_active Ceased
- 2013-09-25 JP JP2015533561A patent/JP6118907B2/ja active Active
- 2013-09-25 US US14/430,919 patent/US9510598B2/en not_active Expired - Fee Related
- 2013-09-27 TW TW102134912A patent/TWI579281B/zh not_active IP Right Cessation
- 2013-09-27 AR ARP130103500A patent/AR092727A1/es unknown
-
2016
- 2016-10-27 US US15/335,832 patent/US9776993B2/en not_active Expired - Fee Related
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