JP2015533491A - 染色体組換え操作に基づく多機能性経口ワクチン - Google Patents

染色体組換え操作に基づく多機能性経口ワクチン Download PDF

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Publication number
JP2015533491A
JP2015533491A JP2015532125A JP2015532125A JP2015533491A JP 2015533491 A JP2015533491 A JP 2015533491A JP 2015532125 A JP2015532125 A JP 2015532125A JP 2015532125 A JP2015532125 A JP 2015532125A JP 2015533491 A JP2015533491 A JP 2015533491A
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antigen
salmonella typhi
ty21a
shigella
region
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JP2015532125A
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Japanese (ja)
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JP2015533491A5 (enExample
Inventor
ダルマセーナ，マドゥシニ・ニロシャ
コペッコ，デニス・ジェイ
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US Department of Health and Human Services
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US Department of Health and Human Services
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Publication of JP2015533491A publication Critical patent/JP2015533491A/ja
Publication of JP2015533491A5 publication Critical patent/JP2015533491A5/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/025—Enterobacteriales, e.g. Enterobacter
    • A61K39/0283—Shigella
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/025—Enterobacteriales, e.g. Enterobacter
    • A61K39/0275—Salmonella
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/25—Shigella (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/255—Salmonella (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/542—Mucosal route oral/gastrointestinal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • General Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2015532125A 2012-09-17 2013-09-16 染色体組換え操作に基づく多機能性経口ワクチン Pending JP2015533491A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261701939P 2012-09-17 2012-09-17
US61/701,939 2012-09-17
PCT/US2013/059980 WO2014043637A1 (en) 2012-09-17 2013-09-16 Multifunctional oral vaccine based on chromosome recombineering

Publications (2)

Publication Number Publication Date
JP2015533491A true JP2015533491A (ja) 2015-11-26
JP2015533491A5 JP2015533491A5 (enExample) 2016-09-01

Family

ID=50278754

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JP2015532125A Pending JP2015533491A (ja) 2012-09-17 2013-09-16 染色体組換え操作に基づく多機能性経口ワクチン

Country Status (9)

Country Link
US (1) US9750793B2 (enExample)
EP (1) EP2895596A4 (enExample)
JP (1) JP2015533491A (enExample)
KR (1) KR20150058435A (enExample)
CN (1) CN104812890A (enExample)
HK (1) HK1211980A1 (enExample)
IL (1) IL237339B (enExample)
IN (1) IN2015KN00516A (enExample)
WO (1) WO2014043637A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2675020T3 (es) * 2013-04-25 2018-07-05 Vaximm Ag Vectores basados en Salmonella para inmunoterapia del cáncer dirigida al gen WT1 del tumor de Wilms
SG11201604911VA (en) 2013-12-18 2016-07-28 Vaximm Gmbh Novel msln targeting dna vaccine for cancer immunotherapy
CN105734001B (zh) * 2014-12-08 2020-04-07 中国人民解放军军事医学科学院生物工程研究所 一种o抗原糖链延长的甲型副伤寒沙门氏菌及其应用
HK1255555A1 (zh) * 2015-07-06 2019-08-23 Protein Potential, Llc 抗志贺氏菌病和伤寒的活性减毒口服疫苗
GB201519734D0 (en) * 2015-11-09 2015-12-23 Univ Swansea Cancer therapy
CN106801029B (zh) * 2017-01-22 2020-05-01 山东大学 一株重组大肠杆菌及其在制备抗志贺氏菌的糖疫苗中的应用
MY190074A (en) * 2018-01-09 2022-03-24 Aimst Univ A monovalent vaccine formulation and a method for preparation thereof
US12180487B2 (en) 2019-02-06 2024-12-31 Fred Hutchinson Cancer Center Minicircle producing bacteria engineered to differentially methylate nucleic acid molecules therein

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120058142A1 (en) * 2002-01-16 2012-03-08 Government of The United States of America, as represented by the The Secretary Vaccine for protection against shigella sonnei disease

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8071113B2 (en) 2004-05-24 2011-12-06 The United States Of America As Represented By The Department Of Health And Human Services Live, oral vaccine for protection against Shigella dysenteriae serotype 1

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120058142A1 (en) * 2002-01-16 2012-03-08 Government of The United States of America, as represented by the The Secretary Vaccine for protection against shigella sonnei disease

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
"Abstracts for the general meeting of the American society for microbiology", 2012.06.01, VOL.112, #817, JPN6017020518, ISSN: 0003780584 *
"FEMS Immunology and Medical Microbiology", 2000, VOL.27, PP.357-364, JPN7017001795, ISSN: 0003570232 *
"Infection and Immunity", 1987, VOL.55, NO.11, PP.2797-2801, JPN6017020521, ISSN: 0003780588 *
"Microbial Pathogenesis", 1988, VOL.5, PP.407-418, JPN6017020519, ISSN: 0003570230 *
"Vaccine", 1993, VOL.11, NO.2, PP.126-135, JPN6017020520, ISSN: 0003780587 *
"Vaccine", 2007, VOL.25, PP.6167-6175, JPN6017020517, ISSN: 0003780583 *

Also Published As

Publication number Publication date
EP2895596A4 (en) 2016-07-27
EP2895596A1 (en) 2015-07-22
IL237339A0 (en) 2015-04-30
US9750793B2 (en) 2017-09-05
KR20150058435A (ko) 2015-05-28
HK1211980A1 (en) 2016-06-03
IN2015KN00516A (enExample) 2015-07-17
CN104812890A (zh) 2015-07-29
WO2014043637A1 (en) 2014-03-20
US20150238591A1 (en) 2015-08-27
IL237339B (en) 2019-06-30

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