JP2015532928A - 充填材料を含有する生体分解可能なマイクロカプセル - Google Patents

充填材料を含有する生体分解可能なマイクロカプセル Download PDF

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Publication number
JP2015532928A
JP2015532928A JP2015533220A JP2015533220A JP2015532928A JP 2015532928 A JP2015532928 A JP 2015532928A JP 2015533220 A JP2015533220 A JP 2015533220A JP 2015533220 A JP2015533220 A JP 2015533220A JP 2015532928 A JP2015532928 A JP 2015532928A
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JP
Japan
Prior art keywords
composition
shell
microcapsules
therapeutic agent
type
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Pending
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JP2015533220A
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English (en)
Japanese (ja)
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JP2015532928A5 (enExample
Inventor
キナム パク，
キナム パク，
クリストファー エー． ローズ，
クリストファー エー． ローズ，
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Akina Inc
OHR Pharma LLC
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Akina Inc
OHR Pharma LLC
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Publication of JP2015532928A publication Critical patent/JP2015532928A/ja
Publication of JP2015532928A5 publication Critical patent/JP2015532928A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4833—Encapsulating processes; Filling of capsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Dermatology (AREA)
JP2015533220A 2012-09-20 2013-09-20 充填材料を含有する生体分解可能なマイクロカプセル Pending JP2015532928A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261703723P 2012-09-20 2012-09-20
US61/703,723 2012-09-20
PCT/US2013/060922 WO2014047439A1 (en) 2012-09-20 2013-09-20 Biodegradable microcapsules containing filling material

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2018178572A Division JP2019014729A (ja) 2012-09-20 2018-09-25 充填材料を含有する生体分解可能なマイクロカプセル

Publications (2)

Publication Number Publication Date
JP2015532928A true JP2015532928A (ja) 2015-11-16
JP2015532928A5 JP2015532928A5 (enExample) 2016-10-20

Family

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JP2015533220A Pending JP2015532928A (ja) 2012-09-20 2013-09-20 充填材料を含有する生体分解可能なマイクロカプセル
JP2018178572A Pending JP2019014729A (ja) 2012-09-20 2018-09-25 充填材料を含有する生体分解可能なマイクロカプセル

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Country Link
US (3) US20150265541A1 (enExample)
EP (1) EP2897593A4 (enExample)
JP (2) JP2015532928A (enExample)
KR (1) KR20150090038A (enExample)
AU (3) AU2013317899A1 (enExample)
BR (1) BR112015006087A2 (enExample)
HK (1) HK1214127A1 (enExample)
MX (2) MX2015003665A (enExample)
WO (1) WO2014047439A1 (enExample)

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US10159743B2 (en) 2012-03-16 2018-12-25 The Johns Hopkins University Non-linear multiblock copolymer-drug conjugates for the delivery of active agents
WO2013166408A1 (en) 2012-05-03 2013-11-07 Kala Pharmaceuticals, Inc. Pharmaceutical nanoparticles showing improved mucosal transport
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WO2017197051A1 (en) 2016-05-10 2017-11-16 C4 Therapeutics, Inc. Amine-linked c3-glutarimide degronimers for target protein degradation
WO2017197036A1 (en) 2016-05-10 2017-11-16 C4 Therapeutics, Inc. Spirocyclic degronimers for target protein degradation
JP7057290B2 (ja) 2016-06-27 2022-04-19 アキリオン ファーマシューティカルズ，インコーポレーテッド 医学的障害を治療するためのキナゾリン及びインドール化合物
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DK3985002T3 (da) 2017-03-01 2025-08-18 Achillion Pharmaceuticals Inc Farmaceutiske aryl-, heteroaryl- og heterocyclylforbindelser til behandling af medicinske forstyrrelser
CN110769822A (zh) 2017-06-20 2020-02-07 C4医药公司 用于蛋白降解的n/o-连接的降解决定子和降解决定子体
WO2019191112A1 (en) 2018-03-26 2019-10-03 C4 Therapeutics, Inc. Cereblon binders for the degradation of ikaros
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KR102272566B1 (ko) * 2019-01-18 2021-07-05 주식회사 대하맨텍 인체에 자극이 없어 안전하고 생분해가 가능한 캡슐 및 그의 제조방법
FR3091878B1 (fr) 2019-01-22 2023-06-16 Calyxia Compositions de produits d’entretien avec des propriétés olfactives améliorées
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JP2023515073A (ja) 2020-02-20 2023-04-12 アキリオン ファーマシューティカルズ， インコーポレーテッド 補体因子ｄ媒介障害の処置用のヘテロアリール化合物
CN115279370B (zh) 2020-03-05 2025-01-10 C4医药公司 用于brd9的靶向降解的化合物
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Also Published As

Publication number Publication date
MX2019002575A (es) 2019-10-30
KR20150090038A (ko) 2015-08-05
BR112015006087A2 (pt) 2017-07-04
MX2015003665A (es) 2016-03-08
US20150265541A1 (en) 2015-09-24
AU2013317899A1 (en) 2015-05-07
WO2014047439A1 (en) 2014-03-27
HK1214127A1 (zh) 2016-10-07
EP2897593A1 (en) 2015-07-29
AU2018204552A1 (en) 2018-07-12
EP2897593A4 (en) 2016-04-06
US20180185296A1 (en) 2018-07-05
JP2019014729A (ja) 2019-01-31
US20200390715A1 (en) 2020-12-17
AU2020202735A1 (en) 2020-05-14
AU2013317899A8 (en) 2015-05-28

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