JP2015532928A5 - - Google Patents
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- Publication number
- JP2015532928A5 JP2015532928A5 JP2015533220A JP2015533220A JP2015532928A5 JP 2015532928 A5 JP2015532928 A5 JP 2015532928A5 JP 2015533220 A JP2015533220 A JP 2015533220A JP 2015533220 A JP2015533220 A JP 2015533220A JP 2015532928 A5 JP2015532928 A5 JP 2015532928A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- shell
- type
- therapeutic agent
- biodegradable polymer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 claims 27
- 239000003814 drug Substances 0.000 claims 24
- 229940124597 therapeutic agent Drugs 0.000 claims 24
- 239000003094 microcapsule Substances 0.000 claims 20
- 229920002988 biodegradable polymer Polymers 0.000 claims 18
- 239000004621 biodegradable polymer Substances 0.000 claims 18
- 239000000463 material Substances 0.000 claims 17
- 239000011859 microparticle Substances 0.000 claims 15
- 239000000945 filler Substances 0.000 claims 10
- 239000007788 liquid Substances 0.000 claims 4
- 239000000499 gel Substances 0.000 claims 3
- 238000000034 method Methods 0.000 claims 3
- 239000011162 core material Substances 0.000 claims 2
- 239000012528 membrane Substances 0.000 claims 2
- 229920005597 polymer membrane Polymers 0.000 claims 2
- 229920006237 degradable polymer Polymers 0.000 claims 1
- 239000000017 hydrogel Substances 0.000 claims 1
- 229920001184 polypeptide Polymers 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 238000007789 sealing Methods 0.000 claims 1
- 229920003169 water-soluble polymer Polymers 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261703723P | 2012-09-20 | 2012-09-20 | |
| US61/703,723 | 2012-09-20 | ||
| PCT/US2013/060922 WO2014047439A1 (en) | 2012-09-20 | 2013-09-20 | Biodegradable microcapsules containing filling material |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018178572A Division JP2019014729A (ja) | 2012-09-20 | 2018-09-25 | 充填材料を含有する生体分解可能なマイクロカプセル |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015532928A JP2015532928A (ja) | 2015-11-16 |
| JP2015532928A5 true JP2015532928A5 (enExample) | 2016-10-20 |
Family
ID=50341971
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015533220A Pending JP2015532928A (ja) | 2012-09-20 | 2013-09-20 | 充填材料を含有する生体分解可能なマイクロカプセル |
| JP2018178572A Pending JP2019014729A (ja) | 2012-09-20 | 2018-09-25 | 充填材料を含有する生体分解可能なマイクロカプセル |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018178572A Pending JP2019014729A (ja) | 2012-09-20 | 2018-09-25 | 充填材料を含有する生体分解可能なマイクロカプセル |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US20150265541A1 (enExample) |
| EP (1) | EP2897593A4 (enExample) |
| JP (2) | JP2015532928A (enExample) |
| KR (1) | KR20150090038A (enExample) |
| AU (3) | AU2013317899A1 (enExample) |
| BR (1) | BR112015006087A2 (enExample) |
| HK (1) | HK1214127A1 (enExample) |
| MX (2) | MX2015003665A (enExample) |
| WO (1) | WO2014047439A1 (enExample) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2538929A4 (en) | 2010-02-25 | 2014-07-09 | Univ Johns Hopkins | DELAYED RELEASE OF THERAPIES IN A PART OF THE EYE |
| US10307372B2 (en) | 2010-09-10 | 2019-06-04 | The Johns Hopkins University | Rapid diffusion of large polymeric nanoparticles in the mammalian brain |
| US9327037B2 (en) | 2011-02-08 | 2016-05-03 | The Johns Hopkins University | Mucus penetrating gene carriers |
| WO2013110028A1 (en) | 2012-01-19 | 2013-07-25 | The Johns Hopkins University | Nanoparticle formulations with enhanced mucosal penetration |
| US8962577B2 (en) | 2012-03-16 | 2015-02-24 | The Johns Hopkins University | Controlled release formulations for the delivery of HIF-1 inhibitors |
| EP2825207B1 (en) | 2012-03-16 | 2020-08-19 | The Johns Hopkins University | Non-linear multiblock copolymer-drug conjugates for the delivery of active agents |
| US11596599B2 (en) | 2012-05-03 | 2023-03-07 | The Johns Hopkins University | Compositions and methods for ophthalmic and/or other applications |
| WO2013166408A1 (en) | 2012-05-03 | 2013-11-07 | Kala Pharmaceuticals, Inc. | Pharmaceutical nanoparticles showing improved mucosal transport |
| US9827191B2 (en) | 2012-05-03 | 2017-11-28 | The Johns Hopkins University | Compositions and methods for ophthalmic and/or other applications |
| WO2013166385A1 (en) | 2012-05-03 | 2013-11-07 | Kala Pharmaceuticals, Inc. | Pharmaceutical nanoparticles showing improved mucosal transport |
| HK1208377A1 (en) | 2012-05-04 | 2016-03-04 | The Johns Hopkins University | Lipid-based drug carriers for rapid penetration through mucus linings |
| US10568975B2 (en) | 2013-02-05 | 2020-02-25 | The Johns Hopkins University | Nanoparticles for magnetic resonance imaging tracking and methods of making and using thereof |
| WO2015127368A1 (en) | 2014-02-23 | 2015-08-27 | The Johns Hopkins University | Hypotonic microbicidal formulations and methods of use |
| EP3250184B1 (en) | 2015-01-27 | 2024-12-18 | The Johns Hopkins University | Hypotonic hydrogel formulations for enhanced transport of active agents at mucosal surfaces |
| AR106018A1 (es) | 2015-08-26 | 2017-12-06 | Achillion Pharmaceuticals Inc | Compuestos de arilo, heteroarilo y heterocíclicos para el tratamiento de trastornos médicos |
| ES2908479T3 (es) | 2015-08-26 | 2022-04-29 | Achillion Pharmaceuticals Inc | Compuestos para el tratamiento de trastornos inmunitarios e inflamatorios |
| US20170273911A1 (en) * | 2016-03-23 | 2017-09-28 | Boston Scientific Scimed Inc. | Injectable microspheres |
| CN109790143A (zh) | 2016-05-10 | 2019-05-21 | C4医药公司 | 用于靶蛋白降解的胺连接的c3-戊二酰亚胺降解决定子体 |
| EP3454862B1 (en) | 2016-05-10 | 2024-09-11 | C4 Therapeutics, Inc. | Spirocyclic degronimers for target protein degradation |
| CN109641874A (zh) | 2016-05-10 | 2019-04-16 | C4医药公司 | 用于靶蛋白降解的c3-碳连接的戊二酰亚胺降解决定子体 |
| WO2017197055A1 (en) | 2016-05-10 | 2017-11-16 | C4 Therapeutics, Inc. | Heterocyclic degronimers for target protein degradation |
| SG11201811491YA (en) | 2016-06-27 | 2019-01-30 | Achillion Pharmaceuticals Inc | Quinazoline and indole compounds to treat medical disorders |
| CA3028751A1 (en) | 2016-07-01 | 2018-01-04 | G1 Therapeutics, Inc. | Pyrimidine-based antiproliferative agents |
| EP3532166B1 (en) * | 2016-10-28 | 2020-09-16 | Unilever N.V. | A personal care composition comprising particles |
| EP3532025B1 (en) | 2016-10-28 | 2021-02-24 | Unilever N.V. | Personal care compositions comprising surface-modified particles and non-volatile functionalised silicone |
| KR102632860B1 (ko) | 2017-03-01 | 2024-02-02 | 아칠리온 파르마세우티칼스 인코포레이티드 | 의학적 장애의 치료를 위한 아릴, 헤테로아릴, 및 헤테로사이클릭 약학적 화합물 |
| CN110769822A (zh) | 2017-06-20 | 2020-02-07 | C4医药公司 | 用于蛋白降解的n/o-连接的降解决定子和降解决定子体 |
| JP2021519337A (ja) | 2018-03-26 | 2021-08-10 | シー4 セラピューティクス, インコーポレイテッド | Ikarosの分解のためのセレブロン結合剤 |
| WO2020041301A1 (en) | 2018-08-20 | 2020-02-27 | Achillion Pharmaceuticals, Inc. | Pharmaceutical compounds for the treatment of complement factor d medical disorders |
| EP3846803A4 (en) | 2018-09-06 | 2022-08-10 | Achillion Pharmaceuticals, Inc. | Macrocyclic compounds for the treatment of medical disorders |
| WO2020081723A1 (en) | 2018-10-16 | 2020-04-23 | Georgia State University Research Foundation, Inc. | Carbon monoxide prodrugs for the treatment of medical disorders |
| KR102272566B1 (ko) * | 2019-01-18 | 2021-07-05 | 주식회사 대하맨텍 | 인체에 자극이 없어 안전하고 생분해가 가능한 캡슐 및 그의 제조방법 |
| WO2020149684A2 (ko) * | 2019-01-18 | 2020-07-23 | 주식회사 대하맨텍 | 인체에 자극이 없어 안전하고 생분해가 가능한 캡슐 및 그의 제조방법 |
| FR3091877B1 (fr) | 2019-01-22 | 2023-06-16 | Calyxia | Compositions de detergence avec des propriétés olfactives améliorées |
| FR3091878B1 (fr) | 2019-01-22 | 2023-06-16 | Calyxia | Compositions de produits d’entretien avec des propriétés olfactives améliorées |
| WO2020210805A1 (en) | 2019-04-11 | 2020-10-15 | The Johns Hopkins University | Nanoparticles for drug delivery to brain |
| BR112021019669A2 (pt) | 2019-04-12 | 2021-12-07 | C4 Therapeutics Inc | Composto, composição farmacêutica, método para tratar um transtorno, composto para uso na produção de um medicamento, e, uso de um composto no tratamento de um transtorno |
| EP4107166A4 (en) | 2020-02-20 | 2024-06-26 | Achillion Pharmaceuticals, Inc. | HETEROARYL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT FACTOR D-MEDIATED DISORDERS |
| WO2021178920A1 (en) | 2020-03-05 | 2021-09-10 | C4 Therapeutics, Inc. | Compounds for targeted degradation of brd9 |
| ES3048084T3 (en) | 2020-05-19 | 2025-12-09 | Pharmacosmos Holding As | Cyclin-dependent kinase inhibiting compounds for the treatment of medical disorders |
| JP7787164B2 (ja) | 2020-09-23 | 2025-12-16 | アキリオン ファーマシューティカルズ, インコーポレーテッド | 補体媒介性障害の治療のための医薬化合物 |
| WO2024184188A1 (en) * | 2023-03-03 | 2024-09-12 | Danmarks Tekniske Universitet | A method for preparing microparticles for drug delivery |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4001388A (en) * | 1973-06-14 | 1977-01-04 | Alza Corporation | Ophthalmological bioerodible drug dispensing formulation |
| US4865846A (en) * | 1988-06-03 | 1989-09-12 | Kaufman Herbert E | Drug delivery system |
| AU2001298061A1 (en) * | 2000-12-13 | 2003-07-09 | Purdue Research Foundation | Microencapsulation of drugs by solvent exchange |
| US8425929B2 (en) * | 2004-04-30 | 2013-04-23 | Allergan, Inc. | Sustained release intraocular implants and methods for preventing retinal dysfunction |
| WO2006041942A2 (en) * | 2004-10-04 | 2006-04-20 | Qlt Usa, Inc. | Ocular delivery of polymeric delivery formulations |
| JP4856881B2 (ja) * | 2005-02-01 | 2012-01-18 | 川澄化学工業株式会社 | 薬剤徐放システム |
| EP1931387A4 (en) * | 2005-09-07 | 2012-07-11 | Southwest Res Inst | BIODEGRADABLE MICROTEILED PHARMACEUTICAL FORMULATIONS WITH IMPROVED RELEASE RATES |
| JP5201763B2 (ja) * | 2007-02-28 | 2013-06-05 | 昇一 城武 | 異なる平均粒径サイズの粒子からなる混合微粒子カプセルの製造方法 |
| US8071119B2 (en) * | 2007-05-14 | 2011-12-06 | Sustained Nano Systems Llc | Controlled release implantable dispensing device and method |
| CA2700356C (en) * | 2007-09-27 | 2013-07-09 | Akina, Inc. | Sol-gel phase-reversible hydrogel templates and uses thereof |
| WO2012054498A1 (en) * | 2010-10-18 | 2012-04-26 | Case Western Reserve University | Polymeric microparticles |
-
2013
- 2013-09-20 WO PCT/US2013/060922 patent/WO2014047439A1/en not_active Ceased
- 2013-09-20 HK HK16101050.7A patent/HK1214127A1/zh unknown
- 2013-09-20 EP EP13838732.9A patent/EP2897593A4/en not_active Withdrawn
- 2013-09-20 MX MX2015003665A patent/MX2015003665A/es unknown
- 2013-09-20 KR KR1020157010168A patent/KR20150090038A/ko not_active Ceased
- 2013-09-20 AU AU2013317899A patent/AU2013317899A1/en not_active Abandoned
- 2013-09-20 US US14/429,304 patent/US20150265541A1/en not_active Abandoned
- 2013-09-20 BR BR112015006087A patent/BR112015006087A2/pt not_active IP Right Cessation
- 2013-09-20 JP JP2015533220A patent/JP2015532928A/ja active Pending
-
2015
- 2015-03-20 MX MX2019002575A patent/MX2019002575A/es unknown
-
2017
- 2017-12-05 US US15/832,368 patent/US20180185296A1/en not_active Abandoned
-
2018
- 2018-06-22 AU AU2018204552A patent/AU2018204552A1/en not_active Abandoned
- 2018-09-25 JP JP2018178572A patent/JP2019014729A/ja active Pending
-
2020
- 2020-04-23 AU AU2020202735A patent/AU2020202735A1/en not_active Abandoned
- 2020-05-26 US US16/883,917 patent/US20200390715A1/en not_active Abandoned
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