JP2015532425A - 粘膜治癒を予測及びモニタリングするための方法 - Google Patents
粘膜治癒を予測及びモニタリングするための方法 Download PDFInfo
- Publication number
- JP2015532425A JP2015532425A JP2015535153A JP2015535153A JP2015532425A JP 2015532425 A JP2015532425 A JP 2015532425A JP 2015535153 A JP2015535153 A JP 2015535153A JP 2015535153 A JP2015535153 A JP 2015535153A JP 2015532425 A JP2015532425 A JP 2015532425A
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- Prior art keywords
- asca
- tnfα
- hgf
- ereg
- egf
- Prior art date
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/06—Gastro-intestinal diseases
- G01N2800/065—Bowel diseases, e.g. Crohn, ulcerative colitis, IBS
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
- Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Pathology (AREA)
- General Health & Medical Sciences (AREA)
- Medical Informatics (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- Databases & Information Systems (AREA)
- Data Mining & Analysis (AREA)
- Epidemiology (AREA)
- Primary Health Care (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261710491P | 2012-10-05 | 2012-10-05 | |
| US61/710,491 | 2012-10-05 | ||
| US201361824959P | 2013-05-17 | 2013-05-17 | |
| US61/824,959 | 2013-05-17 | ||
| PCT/IB2013/059077 WO2014054013A1 (en) | 2012-10-05 | 2013-10-02 | Methods for predicting and monitoring mucosal healing |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015532425A true JP2015532425A (ja) | 2015-11-09 |
| JP2015532425A5 JP2015532425A5 (cg-RX-API-DMAC10.html) | 2016-11-24 |
Family
ID=49447587
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015535153A Pending JP2015532425A (ja) | 2012-10-05 | 2013-10-02 | 粘膜治癒を予測及びモニタリングするための方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20150355195A1 (cg-RX-API-DMAC10.html) |
| EP (3) | EP3640645A1 (cg-RX-API-DMAC10.html) |
| JP (1) | JP2015532425A (cg-RX-API-DMAC10.html) |
| CN (1) | CN104838270A (cg-RX-API-DMAC10.html) |
| AU (2) | AU2013326070A1 (cg-RX-API-DMAC10.html) |
| CA (1) | CA2887035A1 (cg-RX-API-DMAC10.html) |
| ES (2) | ES2638971T3 (cg-RX-API-DMAC10.html) |
| HK (1) | HK1213051A1 (cg-RX-API-DMAC10.html) |
| MX (1) | MX358730B (cg-RX-API-DMAC10.html) |
| SG (1) | SG11201502646RA (cg-RX-API-DMAC10.html) |
| WO (1) | WO2014054013A1 (cg-RX-API-DMAC10.html) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2020523560A (ja) * | 2017-05-31 | 2020-08-06 | プロメテウス バイオサイエンシーズ インコーポレイテッド | クローン病患者の粘膜治癒を評価する方法 |
| JP2020198884A (ja) * | 2016-07-05 | 2020-12-17 | ケンブリッジ エンタープライズ リミテッド | 炎症性腸疾患用のバイオマーカー |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3295783A1 (en) | 2011-05-10 | 2026-03-02 | Prometheus Laboratories, Inc. | Methods of disease activity profiling for personalized therapy management |
| WO2016063223A1 (en) * | 2014-10-20 | 2016-04-28 | Nestec S.A. | Methods for predicting clinical outcomes in subjects afflicted with ulcerative colitis |
| US20170258820A1 (en) | 2014-10-29 | 2017-09-14 | Glycom A/S | Synthetic composition and method for promoting mucosal healing |
| GB201501612D0 (en) * | 2015-01-30 | 2015-03-18 | Univ Birmingham | Assay |
| CN109462996A (zh) | 2016-03-17 | 2019-03-12 | 西达-赛奈医疗中心 | 通过rnaset2诊断炎性肠病的方法 |
| WO2020112890A1 (en) | 2018-11-29 | 2020-06-04 | Cedars-Sinai Medical Center | Rnaset2 compositions and methods of treatment therewith |
| CN110646620A (zh) * | 2019-09-29 | 2020-01-03 | 湖北新纵科病毒疾病工程技术有限公司 | 一种同时检测四项炎症标志物的方法及其试剂盒 |
| CN111477325A (zh) * | 2020-04-09 | 2020-07-31 | 赣南师范大学 | 基于粒子群优化算法对引发肠道溃疡疾病进行鉴别的方法 |
| CN120600283B (zh) * | 2025-05-29 | 2026-02-17 | 北京大学第三医院(北京大学第三临床医学院) | 一种基于临床知识图谱的中医生殖内分泌疾病诊断辅助系统 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006521537A (ja) * | 2003-04-01 | 2006-09-21 | ザ プロクター アンド ギャンブル カンパニー | 腸の炎症性疾患の治療の有効性を決定する方法 |
| WO2011066458A2 (en) * | 2009-11-25 | 2011-06-03 | Prometheus Laboratories Inc. | Novel genomic biomarkers for irritable bowel syndrome diagnosis |
| WO2011153501A2 (en) * | 2010-06-04 | 2011-12-08 | Prometheus Laboratories Inc. | Methods for improving inflammatory bowel disease diagnosis |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5830675A (en) | 1993-03-10 | 1998-11-03 | Cedars-Sinai Medical Center | Methods for selectively detecting perinuclear anti-neutrophil cytoplasmic antibody of ulcerative colitis, primary sclerosing cholangitis, or type 1 autoimmune hepatitis |
| EP0615129B1 (en) | 1993-03-10 | 2000-05-31 | Cedars-Sinai Medical Center | Methods for selectively detecting perinuclear anti-neutrophil cytoplasmic antibody of ulcerative colitis or primary sclerosing cholangitis |
| US6218129B1 (en) | 1998-05-15 | 2001-04-17 | Prometheus Laboratories, Inc. | Inflammatory bowel disease first step assay system |
| US6406862B1 (en) | 1998-10-06 | 2002-06-18 | The United States Of America As Represented By The Secretary Of The Army | Dip-stick assay for C-reactive protein |
| FR2802536B1 (fr) | 1999-11-23 | 2003-06-13 | Chru Lille | Oligomannosides de synthese, leur preparation et leur utilisation a la detection d'anticorps et a la prevention d'infections |
| US6838250B2 (en) | 2000-03-31 | 2005-01-04 | Ortho-Clinical Diagnostics, Inc. | Immunoassay for C-reactive protein |
| AU2001253746A1 (en) * | 2000-04-20 | 2001-11-07 | The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services | Inducible plasmid vector encoding tgf-beta and uses thereof |
| US7138237B1 (en) | 2000-05-19 | 2006-11-21 | Cedars-Sinai Medical Center | Diagnosis, prevention and treatment of Crohn's disease using the OmpC antigen |
| EP1581119B1 (en) | 2001-12-17 | 2013-01-30 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of inflammatory bowel disease |
| CA2549971A1 (en) | 2003-11-03 | 2005-05-12 | Duke University | Methods of identifying individuals at risk of perioperative bleeding, renal dysfunction or stroke |
| WO2006012472A1 (en) | 2004-07-21 | 2006-02-02 | Qualyst, Inc. | Apparatus, kits and methods for evaluating binding interactions, for detecting and quantifying binding molecules, and for sample preparation |
| WO2007087576A2 (en) | 2006-01-24 | 2007-08-02 | The Uab Research Foundation | Compositions and methods for the identification and treatment of immune-mediated inflammatory diseases |
| CN104198705B (zh) | 2006-09-21 | 2017-06-09 | 雀巢产品技术援助有限公司 | 检测稀有循环细胞内多种信号转导分子的基于抗体的阵列 |
| NZ582618A (en) | 2007-07-13 | 2012-07-27 | Prometheus Lab Inc | Drug selection for lung cancer therapy using antibody-based arrays |
| ES2553390T3 (es) | 2008-02-25 | 2015-12-09 | Nestec S.A. | Método para la detección de receptores truncados intracelulares |
| CN101780269A (zh) * | 2009-01-21 | 2010-07-21 | 北京三有利科技发展有限公司 | 细胞生长因子治疗溃疡性疾病和肺纤维化疾病的应用 |
| NZ596468A (en) | 2009-05-14 | 2013-11-29 | Nestec Sa | Biomarkers for determining sensitivity of breast cancer cells to her2-targeted therapy |
| JP5795311B2 (ja) | 2009-07-15 | 2015-10-14 | ネステク ソシエテ アノニム | 抗体ベースのアレイを使用する胃癌療法のための薬物選択 |
| DK2491385T3 (en) | 2009-10-20 | 2017-08-28 | Diatech Holdings Inc | PROXIMITY-MEDIED ASSAYS FOR DETECTING ONCOGEN FUSION PROTEINS |
| CN104634955B (zh) | 2009-10-26 | 2016-09-14 | 雀巢产品技术援助有限公司 | 检测抗-tnf药物和自身抗体的试验 |
| WO2012054532A1 (en) | 2010-10-18 | 2012-04-26 | Prometheus Laboratories Inc. | Methods for determining anti-drug antibody isotypes |
| SG191230A1 (en) | 2010-12-23 | 2013-07-31 | Nestec Sa | Drug selection for malignant cancer therapy using antibody-based arrays |
| MX343327B (es) | 2011-02-17 | 2016-11-01 | Nestec Sa | Ensayos para detectar autoanticuerpos contra farmacos anti-tnfa. |
| EP2681552A2 (en) | 2011-03-02 | 2014-01-08 | Nestec S.A. | Prediction of drug sensitivity of lung tumors based on molecular and genetic signatures |
| WO2013006810A1 (en) | 2011-07-06 | 2013-01-10 | Nestec Sa | Assays for detecting neutralizing autoantibodies to biologic therapy with tnf alpha |
| KR101851425B1 (ko) | 2011-09-02 | 2018-04-23 | 네스텍 소시에테아노님 | 치료 효능 결정을 위한 신호 경로 단백질의 프로파일링 |
-
2013
- 2013-10-02 ES ES13779638.9T patent/ES2638971T3/es active Active
- 2013-10-02 CA CA2887035A patent/CA2887035A1/en not_active Abandoned
- 2013-10-02 EP EP19212960.9A patent/EP3640645A1/en not_active Withdrawn
- 2013-10-02 JP JP2015535153A patent/JP2015532425A/ja active Pending
- 2013-10-02 SG SG11201502646RA patent/SG11201502646RA/en unknown
- 2013-10-02 EP EP17167637.2A patent/EP3217179B9/en active Active
- 2013-10-02 HK HK16100852.9A patent/HK1213051A1/zh unknown
- 2013-10-02 AU AU2013326070A patent/AU2013326070A1/en not_active Abandoned
- 2013-10-02 MX MX2015004272A patent/MX358730B/es active IP Right Grant
- 2013-10-02 EP EP13779638.9A patent/EP2904405B1/en not_active Not-in-force
- 2013-10-02 ES ES17167637T patent/ES2771127T3/es active Active
- 2013-10-02 WO PCT/IB2013/059077 patent/WO2014054013A1/en not_active Ceased
- 2013-10-02 CN CN201380063566.2A patent/CN104838270A/zh active Pending
-
2015
- 2015-04-03 US US14/678,455 patent/US20150355195A1/en not_active Abandoned
-
2019
- 2019-06-19 AU AU2019204276A patent/AU2019204276A1/en not_active Abandoned
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006521537A (ja) * | 2003-04-01 | 2006-09-21 | ザ プロクター アンド ギャンブル カンパニー | 腸の炎症性疾患の治療の有効性を決定する方法 |
| WO2011066458A2 (en) * | 2009-11-25 | 2011-06-03 | Prometheus Laboratories Inc. | Novel genomic biomarkers for irritable bowel syndrome diagnosis |
| WO2011153501A2 (en) * | 2010-06-04 | 2011-12-08 | Prometheus Laboratories Inc. | Methods for improving inflammatory bowel disease diagnosis |
Non-Patent Citations (1)
| Title |
|---|
| GEBOES K ET AL.: "Endoscopic and histologic evidence of persistent mucosal healing and correlation with clinical impro", CURR MED RES OPIN., vol. 21, no. 11, JPN6017032788, 2005, pages 1741 - 1754, ISSN: 0003629825 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2020198884A (ja) * | 2016-07-05 | 2020-12-17 | ケンブリッジ エンタープライズ リミテッド | 炎症性腸疾患用のバイオマーカー |
| JP7111630B2 (ja) | 2016-07-05 | 2022-08-02 | ケンブリッジ エンタープライズ リミテッド | 炎症性腸疾患用のバイオマーカー |
| JP2020523560A (ja) * | 2017-05-31 | 2020-08-06 | プロメテウス バイオサイエンシーズ インコーポレイテッド | クローン病患者の粘膜治癒を評価する方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2019204276A1 (en) | 2019-07-04 |
| CA2887035A1 (en) | 2014-04-10 |
| ES2771127T3 (es) | 2020-07-06 |
| MX2015004272A (es) | 2015-08-14 |
| CN104838270A (zh) | 2015-08-12 |
| AU2013326070A1 (en) | 2015-04-23 |
| EP3217179A1 (en) | 2017-09-13 |
| ES2638971T3 (es) | 2017-10-24 |
| SG11201502646RA (en) | 2015-05-28 |
| EP3217179B1 (en) | 2020-01-08 |
| EP2904405B1 (en) | 2017-05-31 |
| EP3217179B9 (en) | 2020-06-10 |
| EP3640645A1 (en) | 2020-04-22 |
| MX358730B (es) | 2018-09-03 |
| WO2014054013A1 (en) | 2014-04-10 |
| US20150355195A1 (en) | 2015-12-10 |
| EP2904405A1 (en) | 2015-08-12 |
| HK1213051A1 (zh) | 2016-06-24 |
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