JP2015531749A5 - - Google Patents
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- Publication number
- JP2015531749A5 JP2015531749A5 JP2015518624A JP2015518624A JP2015531749A5 JP 2015531749 A5 JP2015531749 A5 JP 2015531749A5 JP 2015518624 A JP2015518624 A JP 2015518624A JP 2015518624 A JP2015518624 A JP 2015518624A JP 2015531749 A5 JP2015531749 A5 JP 2015531749A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- oral pharmaceutical
- pharmaceutical composition
- conditions
- itraconazole
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 claims 37
- 239000008203 oral pharmaceutical composition Substances 0.000 claims 33
- VHVPQPYKVGDNFY-DFMJLFEVSA-N 2-[(2r)-butan-2-yl]-4-[4-[4-[4-[[(2r,4s)-2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-1,2,4-triazol-3-one Chemical compound O=C1N([C@H](C)CC)N=CN1C1=CC=C(N2CCN(CC2)C=2C=CC(OC[C@@H]3O[C@](CN4N=CN=C4)(OC3)C=3C(=CC(Cl)=CC=3)Cl)=CC=2)C=C1 VHVPQPYKVGDNFY-DFMJLFEVSA-N 0.000 claims 13
- 229960004130 itraconazole Drugs 0.000 claims 13
- 235000020937 fasting conditions Nutrition 0.000 claims 5
- 239000002202 Polyethylene glycol Substances 0.000 claims 4
- 239000002775 capsule Substances 0.000 claims 4
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 claims 4
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims 4
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 claims 4
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims 4
- 239000011159 matrix material Substances 0.000 claims 4
- 229920001223 polyethylene glycol Polymers 0.000 claims 4
- 229920000642 polymer Polymers 0.000 claims 4
- 230000001747 exhibiting effect Effects 0.000 claims 2
- 230000009246 food effect Effects 0.000 claims 1
- 235000021471 food effect Nutrition 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2012902624 | 2012-06-21 | ||
| AU2012902624A AU2012902624A0 (en) | 2012-06-21 | Itraconazole formulations and uses | |
| PCT/US2013/047135 WO2013192566A1 (en) | 2012-06-21 | 2013-06-21 | Itraconazole compositions and dosage forms, and methods of using the same |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018126027A Division JP6757367B2 (ja) | 2012-06-21 | 2018-07-02 | イトラコナゾール組成物及び投与剤形、並びにその使用方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015531749A JP2015531749A (ja) | 2015-11-05 |
| JP2015531749A5 true JP2015531749A5 (https=) | 2016-08-12 |
Family
ID=49769445
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015518624A Pending JP2015531749A (ja) | 2012-06-21 | 2013-06-21 | イトラコナゾール組成物及び投与剤形、並びにその使用方法 |
| JP2018126027A Active JP6757367B2 (ja) | 2012-06-21 | 2018-07-02 | イトラコナゾール組成物及び投与剤形、並びにその使用方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018126027A Active JP6757367B2 (ja) | 2012-06-21 | 2018-07-02 | イトラコナゾール組成物及び投与剤形、並びにその使用方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (7) | US8921374B2 (https=) |
| EP (1) | EP2863911A4 (https=) |
| JP (2) | JP2015531749A (https=) |
| KR (3) | KR20200065093A (https=) |
| CN (2) | CN104507480A (https=) |
| AU (3) | AU2013278001A1 (https=) |
| BR (1) | BR112014031706A8 (https=) |
| CA (1) | CA2876909C (https=) |
| HK (1) | HK1207288A1 (https=) |
| MX (1) | MX366829B (https=) |
| WO (1) | WO2013192566A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112014031706A8 (pt) | 2012-06-21 | 2021-10-19 | Mayne Pharma Int Pty Ltd | Composições farmacêuticas orais, e composição farmacêutica oral compreendendo itraconazol |
| US9192609B2 (en) | 2013-04-17 | 2015-11-24 | Hedgepath Pharmaceuticals, Inc. | Treatment and prognostic monitoring of proliferation disorders using hedgehog pathway inhibitors |
| US11390613B2 (en) | 2017-08-20 | 2022-07-19 | University Of Connecticut | Azole analogues and methods of use thereof |
| AU2019277362A1 (en) * | 2018-05-30 | 2021-01-21 | Mayne Pharma International Pty Ltd | Hedgehog pathway inhibition for treatment of high-risk basal cell carcinoma or high-risk basal cell carcinoma nevus syndrome |
| WO2021030174A1 (en) | 2019-08-09 | 2021-02-18 | University Of Connecticut | Truncated itraconazole analogues and methods of use thereof |
| CN115768779A (zh) * | 2020-05-07 | 2023-03-07 | 上海偕怡医药科技有限公司 | 伊曲康唑前药及其用途 |
| WO2023007514A1 (en) * | 2021-07-29 | 2023-02-02 | Dr. Reddy's Laboratories Limited | Improved oral bioavailable pharmaceutical compositions |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3110794B2 (ja) | 1991-06-05 | 2000-11-20 | ユーシービージャパン株式会社 | １，４−ジヒドロピリジン誘導体を含有する製剤 |
| US5340591A (en) | 1992-01-24 | 1994-08-23 | Fujisawa Pharmaceutical Co., Ltd. | Method of producing a solid dispersion of the sparingly water-soluble drug, nilvadipine |
| PH30929A (en) * | 1992-09-03 | 1997-12-23 | Janssen Pharmaceutica Nv | Beads having a core coated with an antifungal and a polymer. |
| US6254889B1 (en) | 1995-07-26 | 2001-07-03 | Kyowa Hakko Kogyo Co., Ltd. | Solid dispersion dosage form of amorphous xanthine derivative and enteric-coating polymer |
| ATE255883T1 (de) | 1996-05-20 | 2003-12-15 | Janssen Pharmaceutica Nv | Fungizide mittel mit verbesserter bioverfügbarkeit |
| DE69730241T2 (de) | 1996-06-28 | 2005-08-11 | Schering Corp. | Feste lösung eines fungizids mit erhöhter bioverfügbarkeit |
| CA2317106C (en) | 1997-12-31 | 2004-11-23 | Choongwae Pharma Corporation | Method and composition of an oral preparation of itraconazole |
| KR100336090B1 (ko) | 1998-06-27 | 2002-05-27 | 윤승원 | 오일, 지방산 또는 이들의 혼합물을 함유한 난용성 약물의 고형분산제제 |
| JP2002534371A (ja) | 1999-01-06 | 2002-10-15 | コリア リサーチ インスティテュート オブ ケミカル テクノロジー | 水不溶性薬物を含む医薬的活性成分の製造方法及びそれを含む経口投与用医薬組成物 |
| EP1027886B1 (en) | 1999-02-10 | 2008-07-09 | Pfizer Products Inc. | Pharmaceutical solid dispersions |
| EP2415462A1 (en) * | 1999-12-23 | 2012-02-08 | Mayne Pharma International Pty Ltd. | Improved pharmaceutical compositions for poorly soluble drugs |
| KR100425755B1 (ko) * | 2001-08-27 | 2004-04-03 | 주식회사 원진신약 | 이트라코나졸을 함유하는 조성물 및 그 제조방법 |
| KR100529766B1 (ko) * | 2003-09-09 | 2005-11-17 | 한미약품 주식회사 | 음식물 섭취에 따른 영향이 적은, 이트라코나졸경구투여용 조성물 및 이의 제조 방법 |
| US20050058670A1 (en) | 2003-09-09 | 2005-03-17 | Jong-Soo Woo | Oral itraconazole composition which is not affected by ingested food and process for preparing same |
| JP4342426B2 (ja) * | 2004-11-24 | 2009-10-14 | 科研製薬株式会社 | イトラコナゾール経口投与用製剤 |
| US8486456B2 (en) * | 2005-08-08 | 2013-07-16 | Abbott Gmbh & Co., Kg | Itraconazole compositions with improved bioavailability |
| WO2008002568A2 (en) * | 2006-06-26 | 2008-01-03 | Mutual Pharmaceutical Company, Inc. | Active agent formulations, methods of making, and methods of use |
| US20110262517A1 (en) * | 2007-04-05 | 2011-10-27 | The Johns Hopkins University | Chirally pure isomers of itraconazole and inhibitors of lanosterol 14a-demethylase for use as angiogenesis inhibitors |
| BR112014031706A8 (pt) | 2012-06-21 | 2021-10-19 | Mayne Pharma Int Pty Ltd | Composições farmacêuticas orais, e composição farmacêutica oral compreendendo itraconazol |
-
2013
- 2013-06-21 BR BR112014031706A patent/BR112014031706A8/pt active Search and Examination
- 2013-06-21 WO PCT/US2013/047135 patent/WO2013192566A1/en not_active Ceased
- 2013-06-21 CA CA2876909A patent/CA2876909C/en active Active
- 2013-06-21 AU AU2013278001A patent/AU2013278001A1/en not_active Abandoned
- 2013-06-21 KR KR1020207015341A patent/KR20200065093A/ko not_active Ceased
- 2013-06-21 CN CN201380040270.9A patent/CN104507480A/zh active Pending
- 2013-06-21 KR KR1020217010610A patent/KR20210043721A/ko not_active Abandoned
- 2013-06-21 MX MX2015000179A patent/MX366829B/es active IP Right Grant
- 2013-06-21 KR KR20157001531A patent/KR20150043296A/ko not_active Ceased
- 2013-06-21 CN CN201811419638.3A patent/CN109674795A/zh active Pending
- 2013-06-21 EP EP13806558.6A patent/EP2863911A4/en active Pending
- 2013-06-21 HK HK15107854.3A patent/HK1207288A1/xx unknown
- 2013-06-21 JP JP2015518624A patent/JP2015531749A/ja active Pending
- 2013-06-21 US US13/924,222 patent/US8921374B2/en active Active
-
2014
- 2014-10-10 US US14/511,420 patent/US9272046B2/en active Active
-
2015
- 2015-10-14 US US14/882,662 patent/US9713642B2/en active Active
-
2017
- 2017-06-15 US US15/623,742 patent/US20170348421A1/en not_active Abandoned
-
2018
- 2018-02-22 AU AU2018201298A patent/AU2018201298B2/en active Active
- 2018-07-02 JP JP2018126027A patent/JP6757367B2/ja active Active
- 2018-11-21 US US16/198,645 patent/US10463740B2/en active Active
-
2019
- 2019-11-01 US US16/671,606 patent/US10806792B2/en active Active
-
2020
- 2020-08-14 AU AU2020217438A patent/AU2020217438A1/en not_active Abandoned
- 2020-10-19 US US17/074,497 patent/US11638758B2/en active Active
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