JP2015531749A5 - - Google Patents
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- Publication number
- JP2015531749A5 JP2015531749A5 JP2015518624A JP2015518624A JP2015531749A5 JP 2015531749 A5 JP2015531749 A5 JP 2015531749A5 JP 2015518624 A JP2015518624 A JP 2015518624A JP 2015518624 A JP2015518624 A JP 2015518624A JP 2015531749 A5 JP2015531749 A5 JP 2015531749A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- oral pharmaceutical
- pharmaceutical composition
- conditions
- itraconazole
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 claims 37
- 239000008203 oral pharmaceutical composition Substances 0.000 claims 33
- VHVPQPYKVGDNFY-DFMJLFEVSA-N 2-[(2r)-butan-2-yl]-4-[4-[4-[4-[[(2r,4s)-2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-1,2,4-triazol-3-one Chemical compound O=C1N([C@H](C)CC)N=CN1C1=CC=C(N2CCN(CC2)C=2C=CC(OC[C@@H]3O[C@](CN4N=CN=C4)(OC3)C=3C(=CC(Cl)=CC=3)Cl)=CC=2)C=C1 VHVPQPYKVGDNFY-DFMJLFEVSA-N 0.000 claims 13
- 229960004130 itraconazole Drugs 0.000 claims 13
- 235000020937 fasting conditions Nutrition 0.000 claims 5
- 239000002202 Polyethylene glycol Substances 0.000 claims 4
- 239000002775 capsule Substances 0.000 claims 4
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 claims 4
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims 4
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 claims 4
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims 4
- 239000011159 matrix material Substances 0.000 claims 4
- 229920001223 polyethylene glycol Polymers 0.000 claims 4
- 229920000642 polymer Polymers 0.000 claims 4
- 230000001747 exhibiting effect Effects 0.000 claims 2
- 230000009246 food effect Effects 0.000 claims 1
- 235000021471 food effect Nutrition 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2012902624 | 2012-06-21 | ||
| AU2012902624A AU2012902624A0 (en) | 2012-06-21 | Itraconazole formulations and uses | |
| PCT/US2013/047135 WO2013192566A1 (en) | 2012-06-21 | 2013-06-21 | Itraconazole compositions and dosage forms, and methods of using the same |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018126027A Division JP6757367B2 (ja) | 2012-06-21 | 2018-07-02 | イトラコナゾール組成物及び投与剤形、並びにその使用方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015531749A JP2015531749A (ja) | 2015-11-05 |
| JP2015531749A5 true JP2015531749A5 (https=) | 2016-08-12 |
Family
ID=49769445
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015518624A Pending JP2015531749A (ja) | 2012-06-21 | 2013-06-21 | イトラコナゾール組成物及び投与剤形、並びにその使用方法 |
| JP2018126027A Active JP6757367B2 (ja) | 2012-06-21 | 2018-07-02 | イトラコナゾール組成物及び投与剤形、並びにその使用方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018126027A Active JP6757367B2 (ja) | 2012-06-21 | 2018-07-02 | イトラコナゾール組成物及び投与剤形、並びにその使用方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (7) | US8921374B2 (https=) |
| EP (1) | EP2863911A4 (https=) |
| JP (2) | JP2015531749A (https=) |
| KR (3) | KR20200065093A (https=) |
| CN (2) | CN109674795A (https=) |
| AU (3) | AU2013278001A1 (https=) |
| BR (1) | BR112014031706A8 (https=) |
| CA (1) | CA2876909C (https=) |
| HK (1) | HK1207288A1 (https=) |
| MX (1) | MX366829B (https=) |
| WO (1) | WO2013192566A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20200065093A (ko) | 2012-06-21 | 2020-06-08 | 메인 파마 인터내셔널 프로프라이어터리 리미티드 | 이트라코나졸 조성물 및 투여형, 그리고 이것들의 사용 방법 |
| US9192609B2 (en) | 2013-04-17 | 2015-11-24 | Hedgepath Pharmaceuticals, Inc. | Treatment and prognostic monitoring of proliferation disorders using hedgehog pathway inhibitors |
| CA3073228A1 (en) | 2017-08-20 | 2019-02-28 | University Of Connecticut | Azole analogues and methods of use thereof |
| US20190365743A1 (en) * | 2018-05-30 | 2019-12-05 | Hedgepath Pharmaceuticals, Inc. | Hedgehog pathway inhibition for treatment of high-risk basal cell carcinoma or high-risk basal cell carcinoma nevus syndrome |
| US12435067B2 (en) | 2019-08-09 | 2025-10-07 | University Of Connecticut | Truncated itraconazole analogues and methods of use thereof |
| US20210346506A1 (en) | 2020-05-07 | 2021-11-11 | Guibai Liang | Prodrug of itraconazole and uses thereof |
| WO2023007514A1 (en) * | 2021-07-29 | 2023-02-02 | Dr. Reddy's Laboratories Limited | Improved oral bioavailable pharmaceutical compositions |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3110794B2 (ja) | 1991-06-05 | 2000-11-20 | ユーシービージャパン株式会社 | １，４−ジヒドロピリジン誘導体を含有する製剤 |
| US5340591A (en) | 1992-01-24 | 1994-08-23 | Fujisawa Pharmaceutical Co., Ltd. | Method of producing a solid dispersion of the sparingly water-soluble drug, nilvadipine |
| PH30929A (en) | 1992-09-03 | 1997-12-23 | Janssen Pharmaceutica Nv | Beads having a core coated with an antifungal and a polymer. |
| DE69628276T2 (de) | 1995-07-26 | 2004-04-08 | Kyowa Hakko Kogyo Co., Ltd. | Zubereitung von xanthinderivaten als feste dispersion |
| WO1997044014A1 (en) | 1996-05-20 | 1997-11-27 | Janssen Pharmaceutica N.V. | Antifungal compositions with improved bioavailability |
| ATE273002T1 (de) | 1996-06-28 | 2004-08-15 | Schering Corp | Feste lösung eines fungizids mit erhöhter bioverfügbarkeit |
| PT1039909E (pt) | 1997-12-31 | 2003-02-28 | Choongwae Pharma Corp | Metodo de producao e composicao de uma preparacao oral de itraconazole |
| KR100336090B1 (ko) | 1998-06-27 | 2002-05-27 | 윤승원 | 오일, 지방산 또는 이들의 혼합물을 함유한 난용성 약물의 고형분산제제 |
| WO2000040220A1 (en) | 1999-01-06 | 2000-07-13 | Korea Research Institute Of Chemical Technology | Method of preparing pharmaceutical active ingredient comprising water-insoluble drug and pharmaceutical composition for oral administration comprising the same |
| ATE400252T1 (de) | 1999-02-10 | 2008-07-15 | Pfizer Prod Inc | Pharmazeutische feste dispersionen |
| EP1239831B1 (en) * | 1999-12-23 | 2012-10-31 | Mayne Pharma International Pty Ltd. | Improved pharmaceutical compositions for poorly soluble drugs |
| KR100425755B1 (ko) * | 2001-08-27 | 2004-04-03 | 주식회사 원진신약 | 이트라코나졸을 함유하는 조성물 및 그 제조방법 |
| KR100529766B1 (ko) | 2003-09-09 | 2005-11-17 | 한미약품 주식회사 | 음식물 섭취에 따른 영향이 적은, 이트라코나졸경구투여용 조성물 및 이의 제조 방법 |
| US20050058670A1 (en) | 2003-09-09 | 2005-03-17 | Jong-Soo Woo | Oral itraconazole composition which is not affected by ingested food and process for preparing same |
| JP4342426B2 (ja) * | 2004-11-24 | 2009-10-14 | 科研製薬株式会社 | イトラコナゾール経口投与用製剤 |
| JP5538718B2 (ja) * | 2005-08-08 | 2014-07-02 | アボット ゲーエムベーハー ウント コンパニー カーゲー | 改善された生物学的利用能をもつイトラコナゾール組成物 |
| BRPI0713533A2 (pt) * | 2006-06-26 | 2012-04-17 | Mutual Pharmaceutical Co | formulações de agente ativo, métodos de fabricação, e métodos de uso |
| WO2008124132A1 (en) * | 2007-04-05 | 2008-10-16 | The Johns Hopkins University | Chirally pure isomers of itraconazole and inhibitors of lanosterol 14a- demethylase for use as angiogenesis inhibitors |
| KR20200065093A (ko) | 2012-06-21 | 2020-06-08 | 메인 파마 인터내셔널 프로프라이어터리 리미티드 | 이트라코나졸 조성물 및 투여형, 그리고 이것들의 사용 방법 |
-
2013
- 2013-06-21 KR KR1020207015341A patent/KR20200065093A/ko not_active Ceased
- 2013-06-21 HK HK15107854.3A patent/HK1207288A1/xx unknown
- 2013-06-21 CN CN201811419638.3A patent/CN109674795A/zh active Pending
- 2013-06-21 CN CN201380040270.9A patent/CN104507480A/zh active Pending
- 2013-06-21 EP EP13806558.6A patent/EP2863911A4/en active Pending
- 2013-06-21 JP JP2015518624A patent/JP2015531749A/ja active Pending
- 2013-06-21 AU AU2013278001A patent/AU2013278001A1/en not_active Abandoned
- 2013-06-21 BR BR112014031706A patent/BR112014031706A8/pt active Search and Examination
- 2013-06-21 US US13/924,222 patent/US8921374B2/en active Active
- 2013-06-21 CA CA2876909A patent/CA2876909C/en active Active
- 2013-06-21 KR KR20157001531A patent/KR20150043296A/ko not_active Ceased
- 2013-06-21 MX MX2015000179A patent/MX366829B/es active IP Right Grant
- 2013-06-21 KR KR1020217010610A patent/KR20210043721A/ko not_active Abandoned
- 2013-06-21 WO PCT/US2013/047135 patent/WO2013192566A1/en not_active Ceased
-
2014
- 2014-10-10 US US14/511,420 patent/US9272046B2/en active Active
-
2015
- 2015-10-14 US US14/882,662 patent/US9713642B2/en active Active
-
2017
- 2017-06-15 US US15/623,742 patent/US20170348421A1/en not_active Abandoned
-
2018
- 2018-02-22 AU AU2018201298A patent/AU2018201298B2/en active Active
- 2018-07-02 JP JP2018126027A patent/JP6757367B2/ja active Active
- 2018-11-21 US US16/198,645 patent/US10463740B2/en active Active
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2019
- 2019-11-01 US US16/671,606 patent/US10806792B2/en active Active
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2020
- 2020-08-14 AU AU2020217438A patent/AU2020217438A1/en not_active Abandoned
- 2020-10-19 US US17/074,497 patent/US11638758B2/en active Active