JP2015530875A5 - - Google Patents
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- Publication number
- JP2015530875A5 JP2015530875A5 JP2015524755A JP2015524755A JP2015530875A5 JP 2015530875 A5 JP2015530875 A5 JP 2015530875A5 JP 2015524755 A JP2015524755 A JP 2015524755A JP 2015524755 A JP2015524755 A JP 2015524755A JP 2015530875 A5 JP2015530875 A5 JP 2015530875A5
- Authority
- JP
- Japan
- Prior art keywords
- vrna
- influenza
- sequence
- cell
- influenza virus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims 21
- 108091034135 Vault RNA Proteins 0.000 claims 17
- 241000712461 unidentified influenza virus Species 0.000 claims 16
- 239000013604 expression vector Substances 0.000 claims 12
- 206010022000 influenza Diseases 0.000 claims 12
- 108091008146 restriction endonucleases Proteins 0.000 claims 12
- 210000004027 cell Anatomy 0.000 claims 10
- 210000004978 chinese hamster ovary cell Anatomy 0.000 claims 10
- 208000015181 infectious disease Diseases 0.000 claims 10
- 230000002458 infectious effect Effects 0.000 claims 10
- 108700007698 Genetic Terminator Regions Proteins 0.000 claims 8
- 241000700605 Viruses Species 0.000 claims 8
- 238000003776 cleavage reaction Methods 0.000 claims 8
- 230000007017 scission Effects 0.000 claims 8
- 239000013598 vector Substances 0.000 claims 8
- 102000017143 RNA Polymerase I Human genes 0.000 claims 7
- 108010013845 RNA Polymerase I Proteins 0.000 claims 7
- 230000000295 complement effect Effects 0.000 claims 7
- 239000013612 plasmid Substances 0.000 claims 6
- 102000004169 proteins and genes Human genes 0.000 claims 6
- 108090000623 proteins and genes Proteins 0.000 claims 6
- 108020004999 messenger RNA Proteins 0.000 claims 5
- 238000005215 recombination Methods 0.000 claims 5
- 230000006798 recombination Effects 0.000 claims 5
- 230000001932 seasonal effect Effects 0.000 claims 5
- 108091081021 Sense strand Proteins 0.000 claims 4
- 101710137500 T7 RNA polymerase Proteins 0.000 claims 4
- 108020004635 Complementary DNA Proteins 0.000 claims 3
- 241000288906 Primates Species 0.000 claims 3
- 239000002299 complementary DNA Substances 0.000 claims 3
- 241000271566 Aves Species 0.000 claims 2
- 241000282465 Canis Species 0.000 claims 2
- 102000053642 Catalytic RNA Human genes 0.000 claims 2
- 108090000994 Catalytic RNA Proteins 0.000 claims 2
- 208000005331 Hepatitis D Diseases 0.000 claims 2
- 208000037262 Hepatitis delta Diseases 0.000 claims 2
- 102000004389 Ribonucleoproteins Human genes 0.000 claims 2
- 108010081734 Ribonucleoproteins Proteins 0.000 claims 2
- 230000000890 antigenic effect Effects 0.000 claims 2
- 230000015572 biosynthetic process Effects 0.000 claims 2
- 208000029570 hepatitis D virus infection Diseases 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 108091092562 ribozyme Proteins 0.000 claims 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
- 241000845082 Panama Species 0.000 claims 1
- 102000009572 RNA Polymerase II Human genes 0.000 claims 1
- 108010009460 RNA Polymerase II Proteins 0.000 claims 1
- 241000283984 Rodentia Species 0.000 claims 1
- 238000010367 cloning Methods 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 241001493065 dsRNA viruses Species 0.000 claims 1
- 238000003306 harvesting Methods 0.000 claims 1
- 230000000415 inactivating effect Effects 0.000 claims 1
- 229960003971 influenza vaccine Drugs 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000012679 serum free medium Substances 0.000 claims 1
- 230000002463 transducing effect Effects 0.000 claims 1
- 210000003501 vero cell Anatomy 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12305968.5 | 2012-08-03 | ||
| EP12305968 | 2012-08-03 | ||
| PCT/EP2013/065920 WO2014019990A1 (en) | 2012-08-03 | 2013-07-29 | Production of infectious influenza viruses |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015530875A JP2015530875A (ja) | 2015-10-29 |
| JP2015530875A5 true JP2015530875A5 (enExample) | 2016-09-08 |
| JP6335167B2 JP6335167B2 (ja) | 2018-05-30 |
Family
ID=48900986
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015524755A Expired - Fee Related JP6335167B2 (ja) | 2012-08-03 | 2013-07-29 | 感染性インフルエンザウイルスの産生 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US9982240B2 (enExample) |
| EP (1) | EP2880154B1 (enExample) |
| JP (1) | JP6335167B2 (enExample) |
| KR (1) | KR20150038374A (enExample) |
| CN (1) | CN104704112A (enExample) |
| AU (1) | AU2013298632B2 (enExample) |
| BR (1) | BR112015002268A2 (enExample) |
| CA (1) | CA2880409A1 (enExample) |
| MX (1) | MX360120B (enExample) |
| SG (1) | SG11201500508XA (enExample) |
| WO (1) | WO2014019990A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112015030582A2 (pt) * | 2013-06-06 | 2017-08-29 | Novartis Ag | Segmento de hemaglutinina da gripe quimérico e de neuraminidase quimérico, proteína de hemaglutinina quimérica, vírus da gripe rearranjado, métodos para preparação de um vírus da gripe rearranjado e para preparação de uma vacina e sistema de expressão |
| CN104232594B (zh) * | 2014-09-11 | 2017-05-31 | 中国农业科学院哈尔滨兽医研究所 | 重组类禽型h1n1流感病毒灭活疫苗株(js40/pr8)及其制备方法和应用 |
| CN105754997B (zh) * | 2016-03-30 | 2019-02-26 | 华中农业大学 | 狂犬病毒drv-ah08株的先导rna及其在制备预防与治疗狂犬病毒的药品中的应用 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1445322B2 (en) | 1995-06-15 | 2012-06-06 | Crucell Holland B.V. | Packaging systems for human recombinant adenovirus to be used in gene therapy |
| TW389999B (en) | 1995-11-21 | 2000-05-11 | Toshiba Corp | Substrate having shallow trench isolation and method of manufacturing the same |
| US6544785B1 (en) | 1998-09-14 | 2003-04-08 | Mount Sinai School Of Medicine Of New York University | Helper-free rescue of recombinant negative strand RNA viruses |
| US8715940B2 (en) | 1999-04-06 | 2014-05-06 | Wisconsin Alumni Research Foundation | Method of making recombinant influenza virus |
| GB9916794D0 (en) * | 1999-07-16 | 1999-09-22 | Isis Innovation | In vitro virus reconstitution |
| GB9923176D0 (en) | 1999-09-30 | 1999-12-01 | Smithkline Beecham Biolog | Novel composition |
| DE60137345D1 (de) | 2000-04-28 | 2009-02-26 | St Jude Childrens Res Hospital | Dna-transfektionssystem zur erzeugung von infektiösen negativsträngigen rna virus |
| ES2230502T3 (es) | 2001-04-23 | 2005-05-01 | Amaxa Gmbh | Disolucion tampon para la electroporacion y procedimiento que incluye el uso de la misma. |
| US20050158342A1 (en) | 2003-12-23 | 2005-07-21 | Medimmune, Inc. | Multi plasmid system for the production of influenza virus |
| US20080254065A1 (en) * | 2004-03-09 | 2008-10-16 | Chiron Corporation | Influenza Virus Vaccines |
| EP1741778B1 (de) | 2005-07-07 | 2007-12-26 | Amaxa AG | Verfahren zur Behandlung geringer Volumina mit elektrischem Strom |
| US20070111309A1 (en) | 2005-10-04 | 2007-05-17 | Daelli Marcelo G | Vero cell line adapted to grow in suspension |
| CN100571775C (zh) * | 2006-11-09 | 2009-12-23 | 中国农业科学院哈尔滨兽医研究所 | 禽流感病毒标记疫苗及其制备方法和应用 |
| EP2296701A1 (en) * | 2008-06-11 | 2011-03-23 | Flugen, Inc. | Cell-based systems for producing influenza vaccines |
| DK2307538T3 (da) | 2008-07-15 | 2016-01-18 | Crucell Holland Bv | Skalérbar fremgangsmåde til dyrkning af per.c6-celler og fremstilling af produkter derfra |
-
2013
- 2013-07-29 SG SG11201500508XA patent/SG11201500508XA/en unknown
- 2013-07-29 AU AU2013298632A patent/AU2013298632B2/en not_active Ceased
- 2013-07-29 EP EP13742451.1A patent/EP2880154B1/en active Active
- 2013-07-29 MX MX2015001499A patent/MX360120B/es active IP Right Grant
- 2013-07-29 WO PCT/EP2013/065920 patent/WO2014019990A1/en not_active Ceased
- 2013-07-29 CN CN201380051942.6A patent/CN104704112A/zh active Pending
- 2013-07-29 BR BR112015002268A patent/BR112015002268A2/pt not_active Application Discontinuation
- 2013-07-29 KR KR1020157004966A patent/KR20150038374A/ko not_active Withdrawn
- 2013-07-29 US US14/419,235 patent/US9982240B2/en active Active
- 2013-07-29 JP JP2015524755A patent/JP6335167B2/ja not_active Expired - Fee Related
- 2013-07-29 CA CA2880409A patent/CA2880409A1/en not_active Abandoned
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