MX360120B - Produccion de virus infecciosos de influenza. - Google Patents
Produccion de virus infecciosos de influenza.Info
- Publication number
- MX360120B MX360120B MX2015001499A MX2015001499A MX360120B MX 360120 B MX360120 B MX 360120B MX 2015001499 A MX2015001499 A MX 2015001499A MX 2015001499 A MX2015001499 A MX 2015001499A MX 360120 B MX360120 B MX 360120B
- Authority
- MX
- Mexico
- Prior art keywords
- production
- influenza viruses
- infectious influenza
- infectious
- relates
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/145—Orthomyxoviridae, e.g. influenza virus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/00051—Methods of production or purification of viral material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/00051—Methods of production or purification of viral material
- C12N2760/00052—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16151—Methods of production or purification of viral material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16161—Methods of inactivation or attenuation
- C12N2760/16164—Methods of inactivation or attenuation by serial passage
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16211—Influenzavirus B, i.e. influenza B virus
- C12N2760/16234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16211—Influenzavirus B, i.e. influenza B virus
- C12N2760/16251—Methods of production or purification of viral material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16211—Influenzavirus B, i.e. influenza B virus
- C12N2760/16261—Methods of inactivation or attenuation
- C12N2760/16264—Methods of inactivation or attenuation by serial passage
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Virology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Plant Pathology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Pharmacology & Pharmacy (AREA)
- Mycology (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
La presente invención se refiere a un método para producir los virus infecciosos de influenza donde las células CHO se infectan con una semilla del virus infeccioso de influenza que se ha generado al transfectar las células con un conjunto apropiado de vectores de expresión. La invención también se relaciona con un casete de recombinación, y con un vector que comprende dicho casete de recombinación, que puede usarse en los métodos para producir los virus infecciosos, y particularmente en el método de acuerdo con la invención.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP12305968 | 2012-08-03 | ||
PCT/EP2013/065920 WO2014019990A1 (en) | 2012-08-03 | 2013-07-29 | Production of infectious influenza viruses |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2015001499A MX2015001499A (es) | 2015-08-20 |
MX360120B true MX360120B (es) | 2018-10-23 |
Family
ID=48900986
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2015001499A MX360120B (es) | 2012-08-03 | 2013-07-29 | Produccion de virus infecciosos de influenza. |
Country Status (11)
Country | Link |
---|---|
US (1) | US9982240B2 (es) |
EP (1) | EP2880154B1 (es) |
JP (1) | JP6335167B2 (es) |
KR (1) | KR20150038374A (es) |
CN (1) | CN104704112A (es) |
AU (1) | AU2013298632B2 (es) |
BR (1) | BR112015002268A2 (es) |
CA (1) | CA2880409A1 (es) |
MX (1) | MX360120B (es) |
SG (1) | SG11201500508XA (es) |
WO (1) | WO2014019990A1 (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SG11201509985XA (en) * | 2013-06-06 | 2016-01-28 | Novartis Ag | Influenza virus reassortment |
CN104232594B (zh) * | 2014-09-11 | 2017-05-31 | 中国农业科学院哈尔滨兽医研究所 | 重组类禽型h1n1流感病毒灭活疫苗株(js40/pr8)及其制备方法和应用 |
CN105754997B (zh) * | 2016-03-30 | 2019-02-26 | 华中农业大学 | 狂犬病毒drv-ah08株的先导rna及其在制备预防与治疗狂犬病毒的药品中的应用 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL122614A0 (en) | 1995-06-15 | 1998-08-16 | Introgene Bv | Packaging systems for human recombinant adenovirus to be used in gene therapy |
TW389999B (en) | 1995-11-21 | 2000-05-11 | Toshiba Corp | Substrate having shallow trench isolation and method of manufacturing the same |
US6544785B1 (en) * | 1998-09-14 | 2003-04-08 | Mount Sinai School Of Medicine Of New York University | Helper-free rescue of recombinant negative strand RNA viruses |
US8715940B2 (en) | 1999-04-06 | 2014-05-06 | Wisconsin Alumni Research Foundation | Method of making recombinant influenza virus |
GB9916794D0 (en) * | 1999-07-16 | 1999-09-22 | Isis Innovation | In vitro virus reconstitution |
GB9923176D0 (en) | 1999-09-30 | 1999-12-01 | Smithkline Beecham Biolog | Novel composition |
PT1317559E (pt) | 2000-04-28 | 2009-02-12 | St Jude Childrens Res Hospital | Sistema de transfecção de adn para a produção de vírus infecciosos de arn de cadeia negativa |
EP1390518B1 (de) | 2001-04-23 | 2004-10-06 | Amaxa GmbH | Pufferlössung für die elektroporation und verfahren umfassend die verwendung derselben |
AU2004308328B2 (en) | 2003-12-23 | 2009-06-04 | Medimmune, Llc | Multi plasmid system for the production of influenza virus |
US20080254065A1 (en) * | 2004-03-09 | 2008-10-16 | Chiron Corporation | Influenza Virus Vaccines |
EP1741778B1 (de) | 2005-07-07 | 2007-12-26 | Amaxa AG | Verfahren zur Behandlung geringer Volumina mit elektrischem Strom |
US20070111309A1 (en) | 2005-10-04 | 2007-05-17 | Daelli Marcelo G | Vero cell line adapted to grow in suspension |
CN100571775C (zh) | 2006-11-09 | 2009-12-23 | 中国农业科学院哈尔滨兽医研究所 | 禽流感病毒标记疫苗及其制备方法和应用 |
US8163523B2 (en) * | 2008-06-11 | 2012-04-24 | Flugen, Inc. | Cell-based systems for producing influenza vaccines |
JP5684122B2 (ja) | 2008-07-15 | 2015-03-11 | クルセル ホランド ベー ヴェー | Per.c6細胞の培養およびそれからの生成物の生産のための拡張可能なプロセス |
-
2013
- 2013-07-29 EP EP13742451.1A patent/EP2880154B1/en active Active
- 2013-07-29 US US14/419,235 patent/US9982240B2/en active Active
- 2013-07-29 JP JP2015524755A patent/JP6335167B2/ja not_active Expired - Fee Related
- 2013-07-29 SG SG11201500508XA patent/SG11201500508XA/en unknown
- 2013-07-29 KR KR1020157004966A patent/KR20150038374A/ko not_active Application Discontinuation
- 2013-07-29 CN CN201380051942.6A patent/CN104704112A/zh active Pending
- 2013-07-29 CA CA2880409A patent/CA2880409A1/en not_active Abandoned
- 2013-07-29 WO PCT/EP2013/065920 patent/WO2014019990A1/en active Application Filing
- 2013-07-29 AU AU2013298632A patent/AU2013298632B2/en not_active Ceased
- 2013-07-29 MX MX2015001499A patent/MX360120B/es active IP Right Grant
- 2013-07-29 BR BR112015002268A patent/BR112015002268A2/pt not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
US9982240B2 (en) | 2018-05-29 |
WO2014019990A1 (en) | 2014-02-06 |
JP6335167B2 (ja) | 2018-05-30 |
CA2880409A1 (en) | 2014-02-06 |
AU2013298632A1 (en) | 2015-02-26 |
AU2013298632B2 (en) | 2018-11-01 |
US20150191703A1 (en) | 2015-07-09 |
BR112015002268A2 (pt) | 2017-11-07 |
JP2015530875A (ja) | 2015-10-29 |
MX2015001499A (es) | 2015-08-20 |
KR20150038374A (ko) | 2015-04-08 |
SG11201500508XA (en) | 2015-02-27 |
EP2880154B1 (en) | 2019-05-15 |
CN104704112A (zh) | 2015-06-10 |
EP2880154A1 (en) | 2015-06-10 |
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