DK2307538T3 - Skalérbar fremgangsmåde til dyrkning af per.c6-celler og fremstilling af produkter derfra - Google Patents

Skalérbar fremgangsmåde til dyrkning af per.c6-celler og fremstilling af produkter derfra Download PDF

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Publication number
DK2307538T3
DK2307538T3 DK09797474.5T DK09797474T DK2307538T3 DK 2307538 T3 DK2307538 T3 DK 2307538T3 DK 09797474 T DK09797474 T DK 09797474T DK 2307538 T3 DK2307538 T3 DK 2307538T3
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DK
Denmark
Prior art keywords
cells
manufacturing products
cultivating
per
scalable procedure
Prior art date
Application number
DK09797474.5T
Other languages
English (en)
Inventor
Maartje Verschuur
Christopher Adam Yallop
Julia Meijer
Original Assignee
Crucell Holland Bv
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Publication date
Application filed by Crucell Holland Bv filed Critical Crucell Holland Bv
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Publication of DK2307538T3 publication Critical patent/DK2307538T3/da

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068General culture methods using substrates
    • C12N5/0075General culture methods using substrates using microcarriers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00Genetically modified cells
    • C12N2510/02Cells for production
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00Genetically modified cells
    • C12N2510/04Immortalised cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00Supports or coatings for cell culture, characterised by material
    • C12N2533/20Small organic molecules

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  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK09797474.5T 2008-07-15 2009-07-09 Skalérbar fremgangsmåde til dyrkning af per.c6-celler og fremstilling af produkter derfra DK2307538T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13499208P 2008-07-15 2008-07-15
EP08160392 2008-07-15
PCT/EP2009/058761 WO2010006989A1 (en) 2008-07-15 2009-07-09 Scalable process for culturing per.c6 cells and producing products therefrom

Publications (1)

Publication Number Publication Date
DK2307538T3 true DK2307538T3 (da) 2016-01-18

Family

ID=40219360

Family Applications (1)

Application Number Title Priority Date Filing Date
DK09797474.5T DK2307538T3 (da) 2008-07-15 2009-07-09 Skalérbar fremgangsmåde til dyrkning af per.c6-celler og fremstilling af produkter derfra

Country Status (11)

Country Link
US (1) US20110159543A1 (da)
EP (1) EP2307538B1 (da)
JP (1) JP5684122B2 (da)
KR (1) KR101639454B1 (da)
CN (1) CN102216449B (da)
AU (1) AU2009272857B2 (da)
CA (1) CA2728477C (da)
DK (1) DK2307538T3 (da)
ES (1) ES2558436T3 (da)
PL (1) PL2307538T3 (da)
WO (1) WO2010006989A1 (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX360120B (es) 2012-08-03 2018-10-23 Sanofi Pasteur Produccion de virus infecciosos de influenza.
TWI480989B (zh) 2012-10-02 2015-04-11 矽品精密工業股份有限公司 半導體封裝件及其製法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4415668A (en) * 1981-04-20 1983-11-15 President And Fellows Of Harvard College Cell culture
US5661008A (en) * 1991-03-15 1997-08-26 Kabi Pharmacia Ab Recombinant human factor VIII derivatives
US5512474A (en) * 1992-05-29 1996-04-30 Bsi Corporation Cell culture support containing a cell adhesion factor and a positively-charged molecule
KR100449181B1 (ko) * 1995-06-15 2005-01-24 크루셀 홀란드 비.브이. 유전자요법에사용할수있는사람의재조합아데노바이러스패키징시스템
JP4210036B2 (ja) * 1999-04-15 2009-01-14 クルセル ホランド ベー ヴェー ヒト細胞における組み換え蛋白質の生産
EP1103610A1 (en) * 1999-11-26 2001-05-30 Introgene B.V. Production of vaccines from immortalised mammalian cell lines
BR0212780A (pt) * 2001-10-02 2004-10-13 Novo Nordisk Healthcare Ag Métodos para produzir polipeptìdeos em células eucarióticas, para cultivar células eucarióticas e para colher polipeptìdeos produzidos por células eucarióticas
DK2102335T3 (da) * 2007-01-04 2012-05-07 Crucell Holland Bv Rensning af faktor XI

Also Published As

Publication number Publication date
KR101639454B1 (ko) 2016-07-13
EP2307538A1 (en) 2011-04-13
CA2728477C (en) 2017-02-28
JP5684122B2 (ja) 2015-03-11
CA2728477A1 (en) 2010-01-21
AU2009272857A1 (en) 2010-01-21
JP2011527894A (ja) 2011-11-10
CN102216449A (zh) 2011-10-12
AU2009272857B2 (en) 2015-06-18
PL2307538T3 (pl) 2016-03-31
US20110159543A1 (en) 2011-06-30
ES2558436T3 (es) 2016-02-04
CN102216449B (zh) 2013-03-06
EP2307538B1 (en) 2015-10-21
WO2010006989A1 (en) 2010-01-21
KR20110041435A (ko) 2011-04-21

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