JP2015529681A5 - - Google Patents

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JP2015529681A5
JP2015529681A5 JP2015532068A JP2015532068A JP2015529681A5 JP 2015529681 A5 JP2015529681 A5 JP 2015529681A5 JP 2015532068 A JP2015532068 A JP 2015532068A JP 2015532068 A JP2015532068 A JP 2015532068A JP 2015529681 A5 JP2015529681 A5 JP 2015529681A5
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pharmaceutically acceptable
acceptable salt
hydrate
compound
salt
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JP2015532068A
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JP6246813B2 (ja
JP2015529681A (ja
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Priority claimed from PCT/US2013/059619 external-priority patent/WO2014043446A1/en
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Publication of JP2015529681A5 publication Critical patent/JP2015529681A5/ja
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JP2015532068A 2012-09-13 2013-09-13 アミノキナゾリンキナーゼ阻害剤のプロドラッグ Expired - Fee Related JP6246813B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261700422P 2012-09-13 2012-09-13
US61/700,422 2012-09-13
US201361767387P 2013-02-21 2013-02-21
US61/767,387 2013-02-21
PCT/US2013/059619 WO2014043446A1 (en) 2012-09-13 2013-09-13 Prodrugs of amino quinazoline kinase inhibitor

Publications (3)

Publication Number Publication Date
JP2015529681A JP2015529681A (ja) 2015-10-08
JP2015529681A5 true JP2015529681A5 (enExample) 2016-10-20
JP6246813B2 JP6246813B2 (ja) 2017-12-13

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JP2015532068A Expired - Fee Related JP6246813B2 (ja) 2012-09-13 2013-09-13 アミノキナゾリンキナーゼ阻害剤のプロドラッグ

Country Status (34)

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US (3) US9586953B2 (enExample)
EP (2) EP2895174B1 (enExample)
JP (1) JP6246813B2 (enExample)
KR (1) KR102101527B1 (enExample)
CN (1) CN104619327B (enExample)
AR (1) AR092529A1 (enExample)
AU (1) AU2013315396B2 (enExample)
BR (1) BR112015005694A2 (enExample)
CA (1) CA2886467C (enExample)
CL (1) CL2015000614A1 (enExample)
CR (1) CR20150132A (enExample)
CY (1) CY1120236T1 (enExample)
DK (1) DK2895174T3 (enExample)
DO (1) DOP2015000060A (enExample)
EA (1) EA028146B1 (enExample)
ES (1) ES2663237T3 (enExample)
HK (1) HK1251222A1 (enExample)
HR (1) HRP20180411T1 (enExample)
HU (1) HUE036347T2 (enExample)
IL (1) IL237263B (enExample)
LT (1) LT2895174T (enExample)
ME (1) ME02985B (enExample)
MX (1) MX371356B (enExample)
NZ (1) NZ628452A (enExample)
PE (1) PE20150635A1 (enExample)
PH (1) PH12015500363A1 (enExample)
PL (1) PL2895174T3 (enExample)
PT (1) PT2895174T (enExample)
RS (1) RS57144B1 (enExample)
SG (1) SG11201501139RA (enExample)
SI (1) SI2895174T1 (enExample)
SM (1) SMT201800158T1 (enExample)
TW (1) TWI592417B (enExample)
WO (1) WO2014043446A1 (enExample)

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TWI592417B (zh) 2012-09-13 2017-07-21 葛蘭素史克智慧財產發展有限公司 胺基喹唑啉激酶抑制劑之前藥
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RU2748260C2 (ru) 2016-04-04 2021-05-21 Кемосентрикс, Инк. РАСТВОРИМЫЕ С5аR АНТАГОНИСТЫ
UA123287C2 (uk) 2016-09-15 2021-03-10 Бьорінгер Інгельхайм Інтернаціональ Гмбх Гетероарилкарбоксамідні сполуки як інгібітори ripk2
WO2020043122A1 (zh) * 2018-08-28 2020-03-05 南京明德新药研发有限公司 作为rip2激酶抑制剂的喹唑啉类衍生物
WO2020094613A1 (en) 2018-11-06 2020-05-14 INSERM (Institut National de la Santé et de la Recherche Médicale) Nod2 inhibitors for the treatment of hereditary periodic fevers
CN114014890A (zh) * 2021-03-12 2022-02-08 爱科诺生物医药(香港)有限公司 具有rip2激酶抑制活性的化合物，包含其的药物组合物，及其应用
WO2025078493A1 (en) * 2023-10-11 2025-04-17 Institut National de la Santé et de la Recherche Médicale Local administration of ripk2 inhibitors for the curative treatment of allergic asthma
WO2025092821A1 (zh) * 2023-11-01 2025-05-08 成都赜灵生物医药科技有限公司 喹唑啉衍生物类ripk2抑制剂及其用途

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TWI592417B (zh) 2012-09-13 2017-07-21 葛蘭素史克智慧財產發展有限公司 胺基喹唑啉激酶抑制劑之前藥
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JP6301374B2 (ja) 2013-02-21 2018-03-28 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドＧｌａｘｏｓｍｉｔｈｋｌｉｎｅ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ Ｄｅｖｅｌｏｐｍｅｎｔ Ｌｉｍｉｔｅｄ キナーゼ阻害剤としてのキナゾリン類

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