JP2015523395A5 - - Google Patents

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Publication number
JP2015523395A5
JP2015523395A5 JP2015524425A JP2015524425A JP2015523395A5 JP 2015523395 A5 JP2015523395 A5 JP 2015523395A5 JP 2015524425 A JP2015524425 A JP 2015524425A JP 2015524425 A JP2015524425 A JP 2015524425A JP 2015523395 A5 JP2015523395 A5 JP 2015523395A5
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JP
Japan
Prior art keywords
pharmaceutical composition
aqueous pharmaceutical
composition according
pirfenidone
aqueous
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2015524425A
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English (en)
Japanese (ja)
Other versions
JP6501264B2 (ja
JP2015523395A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2013/051880 external-priority patent/WO2014018668A2/en
Publication of JP2015523395A publication Critical patent/JP2015523395A/ja
Publication of JP2015523395A5 publication Critical patent/JP2015523395A5/ja
Application granted granted Critical
Publication of JP6501264B2 publication Critical patent/JP6501264B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2015524425A 2012-07-24 2013-07-24 エアロゾルのピルフェニドン及びピリドンのアナログの化合物、及び、その使用 Active JP6501264B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201261675286P 2012-07-24 2012-07-24
US61/675,286 2012-07-24
US201361756983P 2013-01-25 2013-01-25
US61/756,983 2013-01-25
US201361824818P 2013-05-17 2013-05-17
US61/824,818 2013-05-17
PCT/US2013/051880 WO2014018668A2 (en) 2012-07-24 2013-07-24 Aerosol pirfenidone and pyridone analog compounds and uses thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2018116525A Division JP2018172402A (ja) 2012-07-24 2018-06-19 エアロゾルのピルフェニドン及びピリドンのアナログの化合物、及び、その使用

Publications (3)

Publication Number Publication Date
JP2015523395A JP2015523395A (ja) 2015-08-13
JP2015523395A5 true JP2015523395A5 (enExample) 2016-09-08
JP6501264B2 JP6501264B2 (ja) 2019-04-17

Family

ID=49997965

Family Applications (5)

Application Number Title Priority Date Filing Date
JP2015524425A Active JP6501264B2 (ja) 2012-07-24 2013-07-24 エアロゾルのピルフェニドン及びピリドンのアナログの化合物、及び、その使用
JP2018116525A Pending JP2018172402A (ja) 2012-07-24 2018-06-19 エアロゾルのピルフェニドン及びピリドンのアナログの化合物、及び、その使用
JP2019224873A Active JP7120984B2 (ja) 2012-07-24 2019-12-12 エアロゾルのピルフェニドン及びピリドンのアナログの化合物、及び、その使用
JP2022024945A Pending JP2022078126A (ja) 2012-07-24 2022-02-21 エアロゾルのピルフェニドン及びピリドンのアナログの化合物、及び、その使用
JP2024040308A Pending JP2024095678A (ja) 2012-07-24 2024-03-14 エアロゾルのピルフェニドン及びピリドンのアナログの化合物、及び、その使用

Family Applications After (4)

Application Number Title Priority Date Filing Date
JP2018116525A Pending JP2018172402A (ja) 2012-07-24 2018-06-19 エアロゾルのピルフェニドン及びピリドンのアナログの化合物、及び、その使用
JP2019224873A Active JP7120984B2 (ja) 2012-07-24 2019-12-12 エアロゾルのピルフェニドン及びピリドンのアナログの化合物、及び、その使用
JP2022024945A Pending JP2022078126A (ja) 2012-07-24 2022-02-21 エアロゾルのピルフェニドン及びピリドンのアナログの化合物、及び、その使用
JP2024040308A Pending JP2024095678A (ja) 2012-07-24 2024-03-14 エアロゾルのピルフェニドン及びピリドンのアナログの化合物、及び、その使用

Country Status (8)

Country Link
EP (1) EP2877164B1 (enExample)
JP (5) JP6501264B2 (enExample)
AU (5) AU2013295800A1 (enExample)
CA (1) CA2880011C (enExample)
ES (1) ES2959198T3 (enExample)
HU (1) HUE063581T2 (enExample)
NZ (1) NZ705260A (enExample)
WO (1) WO2014018668A2 (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10105356B2 (en) 2011-01-31 2018-10-23 Avalyn Pharma Inc. Aerosol pirfenidone and pyridone analog compounds and uses thereof
WO2012106382A1 (en) 2011-01-31 2012-08-09 Genoa Pharmaceuticals, Inc. Aerosol pirfenidone and pyridone analog compounds and uses thereof
AR092742A1 (es) 2012-10-02 2015-04-29 Intermune Inc Piridinonas antifibroticas
AU2014296032A1 (en) 2013-07-31 2016-03-17 Windward Pharma, Inc. Aerosol tyrosine kinase inhibitor compounds and uses thereof
NZ722927A (en) 2014-01-10 2022-07-29 Avalyn Pharma Inc Aerosol pirfenidone and pyridone analog compounds and uses thereof
MX382781B (es) 2014-04-02 2025-03-13 Intermune Inc Piridinonas anti-fibroticas.
KR102599512B1 (ko) * 2016-03-28 2023-11-07 프레시지 바이오싸이언시스, 인크. 암 치료를 위한 제약학적 조합물
WO2018071443A1 (en) * 2016-10-11 2018-04-19 Microdose Therapeutx, Inc. Inhaler and methods of use thereof
WO2018234527A1 (en) * 2017-06-22 2018-12-27 Softhale Nv Aerosol delivery of pirfenidone
ES3032673T3 (en) 2017-06-22 2025-07-23 Invox Belgium Nv Aerosol delivery of pirfenidone
GB201807050D0 (en) * 2018-04-30 2018-06-13 Cellprotect Nordic Pharmaceuticals Ab Medical uses
EP4424379A3 (en) 2019-04-24 2024-10-30 Convergene Llc Small molecule bromodomain inhibitors and uses thereof
EP3976569B1 (en) * 2019-05-27 2023-11-08 DSM IP Assets B.V. Selective hydrogenation of alkynols to alkenols in the presence of a phosphorus compound
KR102584268B1 (ko) * 2020-04-22 2023-10-05 영진약품 주식회사 안전성과 안정성이 개선된 피르페니돈을 포함하는 장용성 제제 및 이의 제조방법
IL303431A (en) * 2020-12-07 2023-08-01 Mannkind Corp Method and composition for the treatment of pulmonary fibrosis
US20230310322A1 (en) * 2022-03-30 2023-10-05 The Chinese University Of Hong Kong Pfd loaded microspheres and method for preparing injectable composite microsphere hydrogel solution from same
CN115970069B (zh) * 2022-12-13 2024-09-24 南通大学附属医院 载吡非尼酮纳米粒子复合涂层输尿管支架管的制备方法
CN119548479A (zh) * 2024-12-31 2025-03-04 延边大学 一种吸入用吡非尼酮溶液及其使用方法

Family Cites Families (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3826255A (en) 1972-06-22 1974-07-30 Hudson Oxygen Therapy Sales Co Intermittent positive pressure breathing manifold
YU41046B (en) 1974-08-22 1986-10-31 Schering Ag Medicine inholating device
ZA757570B (en) 1974-12-09 1977-07-27 Affiliated Med Res A useful n-substituted pyridone
US4268460A (en) 1977-12-12 1981-05-19 Warner-Lambert Company Nebulizer
US4253468A (en) 1978-08-14 1981-03-03 Steven Lehmbeck Nebulizer attachment
US4263907A (en) 1979-05-14 1981-04-28 Lindsey Joseph W Respirator nebulizer
US4510929A (en) 1982-04-30 1985-04-16 Bordoni Maurice E Disposable radioactive aerosol inhalation apparatus
US4649911A (en) 1983-09-08 1987-03-17 Baylor College Of Medicine Small particle aerosol generator for treatment of respiratory disease including the lungs
US4624251A (en) 1984-09-13 1986-11-25 Riker Laboratories, Inc. Apparatus for administering a nebulized substance
US5152456A (en) 1989-12-12 1992-10-06 Bespak, Plc Dispensing apparatus having a perforate outlet member and a vibrating device
US5164740A (en) 1991-04-24 1992-11-17 Yehuda Ivri High frequency printing mechanism
EP0540775B1 (de) 1991-11-07 1997-07-23 PAUL RITZAU PARI-WERK GmbH Vernebler insbesondere zur Anwendung in Geräten für die Inhalationstherapie
ATE131421T1 (de) 1991-12-04 1995-12-15 The Technology Partnership Plc Vorrichtung und verfahren zur erzeugung von fluessigkeitstroepfchen
US5558085A (en) 1993-01-29 1996-09-24 Aradigm Corporation Intrapulmonary delivery of peptide drugs
US5934272A (en) 1993-01-29 1999-08-10 Aradigm Corporation Device and method of creating aerosolized mist of respiratory drug
US5709202A (en) 1993-05-21 1998-01-20 Aradigm Corporation Intrapulmonary delivery of aerosolized formulations
CA2213638C (en) 1995-02-24 2004-05-04 Nanosystems L.L.C. Aerosols containing nanoparticle dispersions
US6427682B1 (en) 1995-04-05 2002-08-06 Aerogen, Inc. Methods and apparatus for aerosolizing a substance
US5758637A (en) 1995-08-31 1998-06-02 Aerogen, Inc. Liquid dispensing apparatus and methods
US5586550A (en) 1995-08-31 1996-12-24 Fluid Propulsion Technologies, Inc. Apparatus and methods for the delivery of therapeutic liquids to the respiratory system
US5823179A (en) 1996-02-13 1998-10-20 1263152 Ontario Inc. Nebulizer apparatus and method
US6083922A (en) 1996-04-02 2000-07-04 Pathogenesis, Corp. Method and a tobramycin aerosol formulation for treatment prevention and containment of tuberculosis
US5906202A (en) 1996-11-21 1999-05-25 Aradigm Corporation Device and method for directing aerosolized mist to a specific area of the respiratory tract
US6349719B2 (en) 1997-02-24 2002-02-26 Aradigm Corporation Formulation and devices for monitoring the efficacy of the delivery of aerosols
DE19713636A1 (de) 1997-04-02 1998-10-08 Pari Gmbh Atemzugsimulator
US5855564A (en) 1997-08-20 1999-01-05 Aradigm Corporation Aerosol extrusion mechanism
ATE215820T1 (de) 1997-10-08 2002-04-15 Sepracor Inc Dosierungsform zur verabreichung von aerosolen
EP1129741B1 (en) 1997-11-19 2006-04-12 Microflow Engineering SA Spray device for an inhaler
US6192876B1 (en) 1997-12-12 2001-02-27 Astra Aktiebolag Inhalation apparatus and method
WO2000016775A1 (en) 1998-09-18 2000-03-30 Mepha Ag Topical formulation of alkyl-, phenyl-pyridone
GB2343122B (en) 1998-10-26 2003-01-08 Medic Aid Ltd Improvements in and relating to nebulisers
US6070575A (en) 1998-11-16 2000-06-06 Aradigm Corporation Aerosol-forming porous membrane with certain pore structure
US6584971B1 (en) 1999-01-04 2003-07-01 Medic-Aid Limited Drug delivery apparatus
US6338443B1 (en) 1999-06-18 2002-01-15 Mercury Enterprises, Inc. High efficiency medical nebulizer
US6962151B1 (en) 1999-11-05 2005-11-08 Pari GmbH Spezialisten für effektive Inhalation Inhalation nebulizer
CA2919286A1 (en) 2000-04-11 2001-10-18 Trudell Medical International Respiratory apparatus
US6601581B1 (en) 2000-11-01 2003-08-05 Advanced Medical Applications, Inc. Method and device for ultrasound drug delivery
DE10102846B4 (de) 2001-01-23 2012-04-12 Pari Pharma Gmbh Aerosolgenerator
ATE298600T1 (de) 2001-10-18 2005-07-15 Pari Gmbh Inhalationstherapievorrichtung
EP1304130B1 (de) 2001-10-18 2004-06-23 PARI GmbH Spezialisten für effektive Inhalation Inhalationstherapievorrichtung
MXPA04003879A (es) 2001-10-24 2005-02-17 Pari Gmbh Equipo para la preparacion de una composicion farmaceutica.
US7550133B2 (en) * 2002-11-26 2009-06-23 Alexza Pharmaceuticals, Inc. Respiratory drug condensation aerosols and methods of making and using them
JP4542743B2 (ja) * 2002-12-26 2010-09-15 Ｋｄｌ株式会社 ピリドン誘導体の溶液状医薬組成物
US7838532B2 (en) 2005-05-18 2010-11-23 Mpex Pharmaceuticals, Inc. Aerosolized fluoroquinolones and uses thereof
CA2693771A1 (en) * 2007-07-13 2009-01-22 Abbott Biotechnology Ltd. Methods and compositions for pulmonary administration of a tnf.alpha. inhibitor
JP2011507968A (ja) * 2007-12-27 2011-03-10 エイヤーズ ファーマシューティカルズ、インク． エアロゾル化ニトライトおよび一酸化窒素供与性化合物ならびにそれらの使用
NO2344129T3 (enExample) * 2008-10-07 2018-07-21
EP2483244A1 (en) * 2009-10-02 2012-08-08 AstraZeneca AB 2-pyridone compounds used as inhibitors of neutrophil elastase
JP6239054B2 (ja) * 2010-11-26 2017-11-29 東芝メディカルシステムズ株式会社 磁気共鳴診断装置
WO2012106382A1 (en) * 2011-01-31 2012-08-09 Genoa Pharmaceuticals, Inc. Aerosol pirfenidone and pyridone analog compounds and uses thereof

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