AU2013295800A1 - Aerosol pirfenidone and pyridone analog compounds - Google Patents
Aerosol pirfenidone and pyridone analog compounds Download PDFInfo
- Publication number
- AU2013295800A1 AU2013295800A1 AU2013295800A AU2013295800A AU2013295800A1 AU 2013295800 A1 AU2013295800 A1 AU 2013295800A1 AU 2013295800 A AU2013295800 A AU 2013295800A AU 2013295800 A AU2013295800 A AU 2013295800A AU 2013295800 A1 AU2013295800 A1 AU 2013295800A1
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- AU
- Australia
- Prior art keywords
- pirfenidone
- pyridone analog
- dose
- lung
- analog compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- 229960003073 pirfenidone Drugs 0.000 title claims abstract description 754
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4418—Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pulmonology (AREA)
- Organic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2018206852A AU2018206852A1 (en) | 2012-07-24 | 2018-07-23 | Aerosol pirfenidone and pyridone analog compounds |
| AU2020201557A AU2020201557B2 (en) | 2012-07-24 | 2020-03-03 | Aerosol pirfenidone and pyridone analog compounds |
| AU2022271417A AU2022271417A1 (en) | 2012-07-24 | 2022-11-16 | Aerosol pirfenidone and pyridone analog compounds |
| AU2024267029A AU2024267029A1 (en) | 2012-07-24 | 2024-11-29 | Aerosol pirfenidone and pyridone analog compounds |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261675286P | 2012-07-24 | 2012-07-24 | |
| US61/675,286 | 2012-07-24 | ||
| US201361756983P | 2013-01-25 | 2013-01-25 | |
| US61/756,983 | 2013-01-25 | ||
| US201361824818P | 2013-05-17 | 2013-05-17 | |
| US61/824,818 | 2013-05-17 | ||
| PCT/US2013/051880 WO2014018668A2 (en) | 2012-07-24 | 2013-07-24 | Aerosol pirfenidone and pyridone analog compounds and uses thereof |
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|---|---|---|---|
| AU2018206852A Division AU2018206852A1 (en) | 2012-07-24 | 2018-07-23 | Aerosol pirfenidone and pyridone analog compounds |
Publications (1)
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|---|---|
| AU2013295800A1 true AU2013295800A1 (en) | 2015-03-19 |
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| AU2013295800A Abandoned AU2013295800A1 (en) | 2012-07-24 | 2013-07-24 | Aerosol pirfenidone and pyridone analog compounds |
| AU2018206852A Abandoned AU2018206852A1 (en) | 2012-07-24 | 2018-07-23 | Aerosol pirfenidone and pyridone analog compounds |
| AU2020201557A Active AU2020201557B2 (en) | 2012-07-24 | 2020-03-03 | Aerosol pirfenidone and pyridone analog compounds |
| AU2022271417A Abandoned AU2022271417A1 (en) | 2012-07-24 | 2022-11-16 | Aerosol pirfenidone and pyridone analog compounds |
| AU2024267029A Pending AU2024267029A1 (en) | 2012-07-24 | 2024-11-29 | Aerosol pirfenidone and pyridone analog compounds |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2018206852A Abandoned AU2018206852A1 (en) | 2012-07-24 | 2018-07-23 | Aerosol pirfenidone and pyridone analog compounds |
| AU2020201557A Active AU2020201557B2 (en) | 2012-07-24 | 2020-03-03 | Aerosol pirfenidone and pyridone analog compounds |
| AU2022271417A Abandoned AU2022271417A1 (en) | 2012-07-24 | 2022-11-16 | Aerosol pirfenidone and pyridone analog compounds |
| AU2024267029A Pending AU2024267029A1 (en) | 2012-07-24 | 2024-11-29 | Aerosol pirfenidone and pyridone analog compounds |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP2877164B1 (enExample) |
| JP (5) | JP6501264B2 (enExample) |
| AU (5) | AU2013295800A1 (enExample) |
| CA (1) | CA2880011C (enExample) |
| ES (1) | ES2959198T3 (enExample) |
| HU (1) | HUE063581T2 (enExample) |
| NZ (1) | NZ705260A (enExample) |
| WO (1) | WO2014018668A2 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US10105356B2 (en) | 2011-01-31 | 2018-10-23 | Avalyn Pharma Inc. | Aerosol pirfenidone and pyridone analog compounds and uses thereof |
| DK2670242T3 (da) | 2011-01-31 | 2022-05-02 | Avalyn Pharma Inc | Aerosolpirfenidon- og pyridonanalogforbindelser og anvendelser deraf |
| AR092742A1 (es) | 2012-10-02 | 2015-04-29 | Intermune Inc | Piridinonas antifibroticas |
| AU2014296032A1 (en) | 2013-07-31 | 2016-03-17 | Windward Pharma, Inc. | Aerosol tyrosine kinase inhibitor compounds and uses thereof |
| AU2015204558B2 (en) | 2014-01-10 | 2020-04-30 | Avalyn Pharma Inc. | Aerosol pirfenidone and pyridone analog compounds and uses thereof |
| RU2692485C2 (ru) | 2014-04-02 | 2019-06-25 | Интермьюн, Инк. | Противофиброзные пиридиноны |
| NZ757763A (en) * | 2016-03-28 | 2025-07-25 | Presage Biosciences Inc | Pharmaceutical combinations for the treatment of cancer |
| WO2018071427A1 (en) * | 2016-10-11 | 2018-04-19 | Microdose Therapeutx, Inc. | Inhaler and methods of use thereof |
| WO2018234527A1 (en) * | 2017-06-22 | 2018-12-27 | Softhale Nv | Aerosol delivery of pirfenidone |
| CN117861026A (zh) * | 2017-06-22 | 2024-04-12 | 索芙特海尔公司 | 用于吡非尼酮气雾剂的吸入装置、储存器以及递送方法 |
| GB201807050D0 (en) * | 2018-04-30 | 2018-06-13 | Cellprotect Nordic Pharmaceuticals Ab | Medical uses |
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| US20220242807A1 (en) * | 2019-05-27 | 2022-08-04 | Dsm Ip Assets B.V. | Selective hydrogenation of alkynes to alkenes in the presence of a phosphorus compound and an organic sulphur compound |
| KR102584268B1 (ko) * | 2020-04-22 | 2023-10-05 | 영진약품 주식회사 | 안전성과 안정성이 개선된 피르페니돈을 포함하는 장용성 제제 및 이의 제조방법 |
| IL303431A (en) * | 2020-12-07 | 2023-08-01 | Mannkind Corp | Method and composition for the treatment of pulmonary fibrosis |
| EP4499095A1 (en) * | 2022-03-30 | 2025-02-05 | The Chinese University of Hong Kong | Pfd loaded microspheres and method for preparing injectable composite microsphere hydrogel solution from same |
| CN115970069B (zh) * | 2022-12-13 | 2024-09-24 | 南通大学附属医院 | 载吡非尼酮纳米粒子复合涂层输尿管支架管的制备方法 |
| CN119548479A (zh) * | 2024-12-31 | 2025-03-04 | 延边大学 | 一种吸入用吡非尼酮溶液及其使用方法 |
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-
2013
- 2013-07-24 ES ES13822166T patent/ES2959198T3/es active Active
- 2013-07-24 CA CA2880011A patent/CA2880011C/en active Active
- 2013-07-24 HU HUE13822166A patent/HUE063581T2/hu unknown
- 2013-07-24 AU AU2013295800A patent/AU2013295800A1/en not_active Abandoned
- 2013-07-24 EP EP13822166.8A patent/EP2877164B1/en active Active
- 2013-07-24 WO PCT/US2013/051880 patent/WO2014018668A2/en not_active Ceased
- 2013-07-24 JP JP2015524425A patent/JP6501264B2/ja active Active
- 2013-07-24 NZ NZ705260A patent/NZ705260A/en unknown
-
2018
- 2018-06-19 JP JP2018116525A patent/JP2018172402A/ja active Pending
- 2018-07-23 AU AU2018206852A patent/AU2018206852A1/en not_active Abandoned
-
2019
- 2019-12-12 JP JP2019224873A patent/JP7120984B2/ja active Active
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2020
- 2020-03-03 AU AU2020201557A patent/AU2020201557B2/en active Active
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2022
- 2022-02-21 JP JP2022024945A patent/JP2022078126A/ja active Pending
- 2022-11-16 AU AU2022271417A patent/AU2022271417A1/en not_active Abandoned
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2024
- 2024-03-14 JP JP2024040308A patent/JP2024095678A/ja active Pending
- 2024-11-29 AU AU2024267029A patent/AU2024267029A1/en active Pending
Also Published As
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|---|---|
| EP2877164A2 (en) | 2015-06-03 |
| NZ705260A (en) | 2017-04-28 |
| HK1210955A1 (en) | 2016-05-13 |
| ES2959198T3 (es) | 2024-02-21 |
| AU2020201557B2 (en) | 2022-08-25 |
| AU2024267029A1 (en) | 2024-12-19 |
| HUE063581T2 (hu) | 2024-01-28 |
| AU2022271417A1 (en) | 2022-12-22 |
| JP2024095678A (ja) | 2024-07-10 |
| EP2877164A4 (en) | 2016-01-13 |
| AU2020201557A1 (en) | 2020-03-26 |
| JP2020073494A (ja) | 2020-05-14 |
| WO2014018668A3 (en) | 2014-10-16 |
| AU2018206852A1 (en) | 2018-08-09 |
| JP7120984B2 (ja) | 2022-08-17 |
| JP2015523395A (ja) | 2015-08-13 |
| EP2877164B1 (en) | 2023-07-05 |
| EP2877164C0 (en) | 2023-07-05 |
| CA2880011A1 (en) | 2014-01-30 |
| JP2022078126A (ja) | 2022-05-24 |
| WO2014018668A2 (en) | 2014-01-30 |
| JP6501264B2 (ja) | 2019-04-17 |
| CA2880011C (en) | 2021-02-16 |
| JP2018172402A (ja) | 2018-11-08 |
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